Gene Symbol | Tjp3 |
Entrez Gene ID | 27375 |
Full Name | tight junction protein 3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Tjp3 cDNA ORF clone
Gene Symbol | Tjp3 |
Entrez Gene ID | 27375 |
Full Name | tight junction protein 3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_013769.3 | NP_038797.2 | tight junction protein ZO-3 isoform 2 |
XM_006513708.3 | XP_006513771.1 | tight junction protein ZO-3 isoform X1 |
NM_001282095.1 | NP_001269024.1 | tight junction protein ZO-3 isoform 2 |
NM_001282096.1 | NP_001269025.1 | tight junction protein ZO-3 isoform 1 |
Pan troglodytes (chimpanzee) | TJP3 | XP_001135804.2 |
Mus musculus (house mouse) | Tjp3 | NP_001269025.1 |
Rattus norvegicus (Norway rat) | Tjp3 | NP_001101543.1 |
Xenopus tropicalis (tropical clawed frog) | tjp3 | XP_002941439.2 |
TJP3 | XP_001117962.1 | |
Bos taurus (cattle) | TJP3 | NP_001039339.1 |
Homo sapiens (human) | TJP3 | NP_001254490.1 |
Canis lupus familiaris (dog) | TJP3 | NP_001003202.1 |
Gallus gallus (chicken) | TJP3 | XP_003642888.2 |
Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion.
Qiao X, Roth I, F?raille E, Hasler U
Cell cycle (Georgetown, Tex.)13(19)3059-75(2014)
Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation.
Capaldo CT, Koch S, Kwon M, Laur O, Parkos CA, Nusrat A
Molecular biology of the cell22(10)1677-85(2011 May)
Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.
Tsukita S, Katsuno T, Yamazaki Y, Umeda K, Tamura A, Tsukita S
Annals of the New York Academy of Sciences116544-52(2009 May)
Serum response factor is required for sprouting angiogenesis and vascular integrity.
Franco CA, Mericskay M, Parlakian A, Gary-Bobo G, Gao-Li J, Paulin D, Gustafsson E, Li Z
Developmental cell15(3)448-61(2008 Sep)
Identification of transcripts with enriched expression in the developing and adult pancreas.
Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD
Genome biology9(6)R99(2008)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ZO-3 shows an epithelial-specific Tight junctions localization
Title: Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function.
Early embryonic lethality of mice lacking Tjp2, but not Tjp3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development.
Title: Early embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development.
ZO-3 (-/-) mice were viable and fertile and their tight junctions did not appear to be affected.
Title: Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein.
The following Tjp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tjp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu09924 | |
Clone ID Related Accession (Same CDS sequence) | NM_013769.3 , XM_006513708.3 , NM_001282095.1 | |
Accession Version | NM_013769.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2715bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-11 | |
Organism | Mus musculus(house mouse) | |
Product | tight junction protein ZO-3 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK134100.1, AK029083.1 and AV236903.1. On Aug 18, 2013 this sequence version replaced NM_013769.2. Transcript Variant: This variant (3) differs in the 5' UTR and coding region, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK134100.1, BC012518.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAAGAGC TGACCATCTG GGAACAACAC ACAGCCACAC TGTACAAGGA CCCCCGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_038797.2 |
CDS | 230..2944 |
Translation |
Target ORF information:
Target ORF information:
|
NM_013769.3 |
1 | ATGGAAGAGC TGACCATCTG GGAACAACAC ACAGCCACAC TGTACAAGGA CCCCCGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09924 | |
Clone ID Related Accession (Same CDS sequence) | NM_013769.3 , XM_006513708.3 , NM_001282095.1 | |
Accession Version | NM_001282095.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2715bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-11 | |
Organism | Mus musculus(house mouse) | |
Product | tight junction protein ZO-3 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK167587.1, AK029083.1 and AV236903.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. The encoded isoform (2) has a shorter and distinct N-terminus, compared to isoform 1. Both variants 2 and 3 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK167587.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAAGAGC TGACCATCTG GGAACAACAC ACAGCCACAC TGTACAAGGA CCCCCGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001269024.1 |
CDS | 128..2842 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001282095.1 |
1 | ATGGAAGAGC TGACCATCTG GGAACAACAC ACAGCCACAC TGTACAAGGA CCCCCGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09924 | |
Clone ID Related Accession (Same CDS sequence) | NM_013769.3 , XM_006513708.3 , NM_001282095.1 | |
Accession Version | XM_006513708.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2715bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | tight junction protein ZO-3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006513708.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAAGAGC TGACCATCTG GGAACAACAC ACAGCCACAC TGTACAAGGA CCCCCGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006513771.1 |
CDS | 307..3021 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006513708.3 |
1 | ATGGAAGAGC TGACCATCTG GGAACAACAC ACAGCCACAC TGTACAAGGA CCCCCGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu08435 | |
Clone ID Related Accession (Same CDS sequence) | NM_001282096.1 | |
Accession Version | NM_001282096.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2742bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-11 | |
Organism | Mus musculus(house mouse) | |
Product | tight junction protein ZO-3 isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC155937.4, BY102203.1, AK029083.1 and AV236903.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCGGTGA GATTCCAGGT GGCAGACATG GAAGAGCTGA CCATCTGGGA ACAACACACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001269025.1 |
CDS | 164..2905 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001282096.1 |
1 | ATGGCGGTGA GATTCCAGGT GGCAGACATG GAAGAGCTGA CCATCTGGGA ACAACACACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Different effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion. |
Tight function zonula occludens-3 regulates cyclin D1-dependent cell proliferation. |
Roles of ZO-1 and ZO-2 in establishment of the belt-like adherens and tight junctions with paracellular permselective barrier function. |
Serum response factor is required for sprouting angiogenesis and vascular integrity. |
Identification of transcripts with enriched expression in the developing and adult pancreas. |