Adam1a cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Adam1a
Entrez Gene ID	280668
Full Name	a disintegrin and metallopeptidase domain 1a
Synonyms	Adam1,Ftna
General protein information	Preferred Names a disintegrin and metallopeptidase domain 1a Names disintegrin and metalloproteinase domain-containing protein 1a ADAM 1a PH-30 alpha a disintegrin and metalloproteinase domain 1a (fertilin alpha) fertilin alpha fertilin subunit alpha-a
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 5 Map Location: 5 F\|5 61.84 cM

mRNA and Protein(s)

mRNA	Protein	Name
NM_172126.2	NP_742124.2	disintegrin and metalloproteinase domain-containing protein 1a precursor

Pathways from BioSystems

Homologies

	ADAM1	XP_001109414.1
Canis lupus familiaris (dog)	LOC477481	XP_534679.4
Rattus norvegicus (Norway rat)	Adam1a	NP_064463.1
Mus musculus (house mouse)	Adam1a	NP_742124.2
Canis lupus familiaris (dog)	LOC100683375	XP_003433462.1

Gene Ontology
Bibliography

Related articles in PubMed

Positive selection in the adhesion domain of Mus sperm Adam genes through gene duplications and function-driven gene complex formations.
Grayson P, Civetta A
BMC evolutionary biology13217(2013 Sep)

Reduced fertility of mouse epididymal sperm lacking Prss21/Tesp5 is rescued by sperm exposure to uterine microenvironment.
Yamashita M, Honda A, Ogura A, Kashiwabara S, Fukami K, Baba T
Genes to cells : devoted to molecular & cellular mechanisms13(10)1001-13(2008 Oct)

Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface.
Nishimura H, Kim E, Nakanishi T, Baba T
The Journal of biological chemistry279(33)34957-62(2004 Aug)

Differential localization of ADAM1a and ADAM1b in the endoplasmic reticulum of testicular germ cells and on the surface of epididymal sperm.
Kim E, Nishimura H, Baba T
Biochemical and biophysical research communications304(2)313-9(2003 May)

The ADAM1a and ADAM1b genes, instead of the ADAM1 (fertilin alpha) gene, are localized on mouse chromosome 5.
Nishimura H, Kim E, Fujimori T, Kashiwabara S, Kuroiwa A, Matsuda Y, Baba T
Gene291(1-2)67-76(2002 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

ADAM1a/ADAM2 Fertilin complex has roles in expression of ADAM3 on the cell surface of mouse sperm
Title: Possible function of the ADAM1a/ADAM2 Fertilin complex in the appearance of ADAM3 on the sperm surface.

Localization of ADAM1a in the endoplasmic reticulum of testicular germ cells and on the surface of epididymal sperm.
Title: Differential localization of ADAM1a and ADAM1b in the endoplasmic reticulum of testicular germ cells and on the surface of epididymal sperm.

The following Adam1a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Adam1a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu58069	NM_172126.2 Latest version!	Mus musculus a disintegrin and metallopeptidase domain 1a (Adam1a), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$391.30 $559.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Adam1a ( NM_172126.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_742124.2 Mus musculus a disintegrin and metallopeptidase domain 1a (Adam1a), mRNA.

Price & Availability↑

CloneID	OMu58069
Clone ID Related Accession (Same CDS sequence)	NM_172126.2
Accession Version	NM_172126.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Mus musculus(house mouse)
Product	disintegrin and metalloproteinase domain-containing protein 1a precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC052093.1. On Jun 10, 2003 this sequence version replaced NM_172126.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript is intronless :: BC052093.1 [ECO:0000345] ##Evidence-Data-END##

ATGTCAGTGG CAGCAGCGGG GAGAGGGTTT GCCTCCAGTC TGTCTTCCCC ACAGATCAGG 
CGAATAGCCT TAAAAGAAGC TAAGCTAACA CCTCACATCT GGGCGGCACT GCACTGGAAC 
TTGGGACTGA GACTAGTGCC ATCTGTCAGA GTAGGGATTT TGGTGCTACT GATTTTTCTC 
CCGAGCACGT TCTGTGACAT TGGATCTGTA TATAATTCTT CCTATGAAAC TGTCATCCCT 
GAGAGACTGC CAGGCAAGGG GGGGAAAGAC CCTGGAGGGA AGGTGTCCTA CATGCTATTG 
ATGCAAGGCC AAAAGCAGCT GCTTCACCTC GAGGTAAAGG GACACTACCC TGAGAATAAC 
TTCCCAGTCT ACAGTTACCA CAATGGCATC CTGAGGCAAG AAATGCCTCT CCTCTCCCAG 
GACTGCCACT ATGAAGGCTA CATGGAAGGG GTGCCAGGCT CCTTTGTTTC TGTCAACATC 
TGTTCAGGCC TCAGGGGGGT CTTGATTAAA GAGGAAACAT CCTATGGCAT TGAGCCCATG 
CTCTCTTCCA AAAACTTTGA ACATGTCCTC TACACCATGG AGCATCAGCC TGTGGTCTCC 
TGCAGTGTCA CTCCCAAAGA CAGCCCTGGG GACACCAGCC ATCCACCAAG GAGCAGGAAG 
CCCGATGACC TACTGGTTCT GACTGACTGG TGGTCACACA CCAAGTATGT GGAGATGTTT 
GTGGTGGTCA ACCACCAGCG GTTCCAGATG TGGGGCAGTA ACATCAACGA GACGGTCCAG 
GCAGTAATGG ACATCATTGC TCTGGCCAAC AGCTTCACTA GGGGGATAAA CACAGAGGTG 
GTGCTGGTGG GCCTGGAAAT CTGGACAGAG GGGGACCCGA TAGAGGTCCC AGTGGACCTG 
CAGACCACAC TCAGGAATTT CAACTTCTGG AGACAGGAGA AACTCGTGGG CCGGGTCAGG 
CACGATGTGG CACACTTGAT CGTCGGGCAT CGCCCAGGAG AGAACGAGGG CCAGGCGTTT 
CTCCGTGGTG CCTGTTCGGG TGAGTTTGCG GCGGCCGTGG AGGCCTTCCA TCATGAAGAT 
GTCCTCCTGT TCGCGGCTCT CATGGCCCAC GAGCTCGGGC ACAACCTGGG TATCCAGCAC 
GACCACCCGA CCTGCACCTG TGGTCCCAAG CACTTCTGCC TCATGGGTGA GAAGATCGGT 
AAGGACAGTG GCTTCAGCAA CTGCAGCTCT GACCACTTCC TCCGTTTCCT CCATGACCAC 
AGAGGGGCGT GCCTGCTTGA TGAGCCTGGG CGCCAGAGCC GCATGCGCAG AGCTGCCAAT 
TGTGGGAATG GTGTGGTGGA GGACTTGGAG GAGTGTGACT GCGGCAGTGA CTGTGACAGT 
CACCCGTGCT GTTCGCCAAC ATGTACGCTT AAGGAGGGTG CGCAGTGCAG TGAGGGACTC 
TGCTGCTACA ACTGTACATT CAAGAAGAAA GGGAGCTTAT GCCGTCCTGC TGAGGATGTG 
TGTGACCTTC CCGAGTATTG TGACGGCAGT ACTCAGGAAT GCCCTGCAAA CAGCTACATG 
CAGGATGGCA CACAGTGTGA TAGGATTTAT TACTGCTTGG GGGGTTGGTG TAAGAACCCT 
GATAAACAAT GTTCAAGGAT CTATGGGTAT CCTGCAAGAT CTGCCCCTGA GGAATGTTAC 
ATTTCAGTTA ATACTAAGGC GAACCGGTTT GGAAACTGTG GCCATCCCAC CTCCGCTAAC 
TTCAGATATG AAACATGTTC CGATGAGGAT GTATTTTGTG GGAAACTGGT GTGTACAGAT 
GTTAGATACC TGCCCAAAGT CAAACCCCTA CACTCACTCC TCCAGGTTCC TTATGGAGAG 
GACTGGTGTT GGAGTATGGA TGCCTATAAC ATCACAGATG TCCCGGATGA CGGAGATGTA 
CAGAGCGGCA CCTTCTGTGC CCCAAACAAA GTCTGCATGG AGTATATCTG CACTGGTCGT 
GGGGTGCTCC AGTACAACTG TGAGCCACAG GAAATGTGTC ACGGGAATGG AGTGTGCAAC 
AATTTCAAGC ACTGTCACTG CGATGCTGGC TTCGCCCCTC CTGACTGTAG CAGTCCAGGA 
AATGGGGGGA GTGTGGACAG TGGTCCTGTT GGTAAGCCCG CTGATCGACA CTTGAGTCTC 
TCTTTTCTGG CTGAAGAGAG TCCAGATGAT AAAATGGAGG ATGAAGAGGT AAACCTGAAA 
GTGATGGTGC TTGTGGTCCC TATATTTCTT GTCGTTTTAC TGTGCTGTCT AATGCTGATC 
GCCTACCTCT GGTCTGAAGT ACAAGAAGTA GTATCTCCAC CGAGTTCATC AGAGTCTTCG 
TCTTCATCAT CCTGGTCAGA CTCTGACTCT CAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_742124.2
CDS	468..2843
Translation	MSVAAAGRGFASSLSSPQIRRIALKEAKLTPHIWAALHWNLGLRLVPSVRVGILVLLIFLPSTFCDIGSVYNSSYETVIPERLPGKGGKDPGGKVSYMLLMQGQKQLLHLEVKGHYPENNFPVYSYHNGILRQEMPLLSQDCHYEGYMEGVPGSFVSVNICSGLRGVLIKEETSYGIEPMLSSKNFEHVLYTMEHQPVVSCSVTPKDSPGDTSHPPRSRKPDDLLVLTDWWSHTKYVEMFVVVNHQRFQMWGSNINETVQAVMDIIALANSFTRGINTEVVLVGLEIWTEGDPIEVPVDLQTTLRNFNFWRQEKLVGRVRHDVAHLIVGHRPGENEGQAFLRGACSGEFAAAVEAFHHEDVLLFAALMAHELGHNLGIQHDHPTCTCGPKHFCLMGEKIGKDSGFSNCSSDHFLRFLHDHRGACLLDEPGRQSRMRRAANCGNGVVEDLEECDCGSDCDSHPCCSPTCTLKEGAQCSEGLCCYNCTFKKKGSLCRPAEDVCDLPEYCDGSTQECPANSYMQDGTQCDRIYYCLGGWCKNPDKQCSRIYGYPARSAPEECYISVNTKANRFGNCGHPTSANFRYETCSDEDVFCGKLVCTDVRYLPKVKPLHSLLQVPYGEDWCWSMDAYNITDVPDDGDVQSGTFCAPNKVCMEYICTGRGVLQYNCEPQEMCHGNGVCNNFKHCHCDAGFAPPDCSSPGNGGSVDSGPVGKPADRHLSLSFLAEESPDDKMEDEEVNLKVMVLVVPIFLVVLLCCLMLIAYLWSEVQEVVSPPSSSESSSSSSWSDSDSQ

Target ORF information:

RefSeq Version	NM_172126.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus a disintegrin and metallopeptidase domain 1a (Adam1a), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_172126.2

ORF Insert Sequence:

ATGTCAGTGG CAGCAGCGGG GAGAGGGTTT GCCTCCAGTC TGTCTTCCCC ACAGATCAGG 
CGAATAGCCT TAAAAGAAGC TAAGCTAACA CCTCACATCT GGGCGGCACT GCACTGGAAC 
TTGGGACTGA GACTAGTGCC ATCTGTCAGA GTAGGGATTT TGGTGCTACT GATTTTTCTC 
CCGAGCACGT TCTGTGACAT TGGATCTGTA TATAATTCTT CCTATGAAAC TGTCATCCCT 
GAGAGACTGC CAGGCAAGGG GGGGAAAGAC CCTGGAGGGA AGGTGTCCTA CATGCTATTG 
ATGCAAGGCC AAAAGCAGCT GCTTCACCTC GAGGTAAAGG GACACTACCC TGAGAATAAC 
TTCCCAGTCT ACAGTTACCA CAATGGCATC CTGAGGCAAG AAATGCCTCT CCTCTCCCAG 
GACTGCCACT ATGAAGGCTA CATGGAAGGG GTGCCAGGCT CCTTTGTTTC TGTCAACATC 
TGTTCAGGCC TCAGGGGGGT CTTGATTAAA GAGGAAACAT CCTATGGCAT TGAGCCCATG 
CTCTCTTCCA AAAACTTTGA ACATGTCCTC TACACCATGG AGCATCAGCC TGTGGTCTCC 
TGCAGTGTCA CTCCCAAAGA CAGCCCTGGG GACACCAGCC ATCCACCAAG GAGCAGGAAG 
CCCGATGACC TACTGGTTCT GACTGACTGG TGGTCACACA CCAAGTATGT GGAGATGTTT 
GTGGTGGTCA ACCACCAGCG GTTCCAGATG TGGGGCAGTA ACATCAACGA GACGGTCCAG 
GCAGTAATGG ACATCATTGC TCTGGCCAAC AGCTTCACTA GGGGGATAAA CACAGAGGTG 
GTGCTGGTGG GCCTGGAAAT CTGGACAGAG GGGGACCCGA TAGAGGTCCC AGTGGACCTG 
CAGACCACAC TCAGGAATTT CAACTTCTGG AGACAGGAGA AACTCGTGGG CCGGGTCAGG 
CACGATGTGG CACACTTGAT CGTCGGGCAT CGCCCAGGAG AGAACGAGGG CCAGGCGTTT 
CTCCGTGGTG CCTGTTCGGG TGAGTTTGCG GCGGCCGTGG AGGCCTTCCA TCATGAAGAT 
GTCCTCCTGT TCGCGGCTCT CATGGCCCAC GAGCTCGGGC ACAACCTGGG TATCCAGCAC 
GACCACCCGA CCTGCACCTG TGGTCCCAAG CACTTCTGCC TCATGGGTGA GAAGATCGGT 
AAGGACAGTG GCTTCAGCAA CTGCAGCTCT GACCACTTCC TCCGTTTCCT CCATGACCAC 
AGAGGGGCGT GCCTGCTTGA TGAGCCTGGG CGCCAGAGCC GCATGCGCAG AGCTGCCAAT 
TGTGGGAATG GTGTGGTGGA GGACTTGGAG GAGTGTGACT GCGGCAGTGA CTGTGACAGT 
CACCCGTGCT GTTCGCCAAC ATGTACGCTT AAGGAGGGTG CGCAGTGCAG TGAGGGACTC 
TGCTGCTACA ACTGTACATT CAAGAAGAAA GGGAGCTTAT GCCGTCCTGC TGAGGATGTG 
TGTGACCTTC CCGAGTATTG TGACGGCAGT ACTCAGGAAT GCCCTGCAAA CAGCTACATG 
CAGGATGGCA CACAGTGTGA TAGGATTTAT TACTGCTTGG GGGGTTGGTG TAAGAACCCT 
GATAAACAAT GTTCAAGGAT CTATGGGTAT CCTGCAAGAT CTGCCCCTGA GGAATGTTAC 
ATTTCAGTTA ATACTAAGGC GAACCGGTTT GGAAACTGTG GCCATCCCAC CTCCGCTAAC 
TTCAGATATG AAACATGTTC CGATGAGGAT GTATTTTGTG GGAAACTGGT GTGTACAGAT 
GTTAGATACC TGCCCAAAGT CAAACCCCTA CACTCACTCC TCCAGGTTCC TTATGGAGAG 
GACTGGTGTT GGAGTATGGA TGCCTATAAC ATCACAGATG TCCCGGATGA CGGAGATGTA 
CAGAGCGGCA CCTTCTGTGC CCCAAACAAA GTCTGCATGG AGTATATCTG CACTGGTCGT 
GGGGTGCTCC AGTACAACTG TGAGCCACAG GAAATGTGTC ACGGGAATGG AGTGTGCAAC 
AATTTCAAGC ACTGTCACTG CGATGCTGGC TTCGCCCCTC CTGACTGTAG CAGTCCAGGA 
AATGGGGGGA GTGTGGACAG TGGTCCTGTT GGTAAGCCCG CTGATCGACA CTTGAGTCTC 
TCTTTTCTGG CTGAAGAGAG TCCAGATGAT AAAATGGAGG ATGAAGAGGT AAACCTGAAA 
GTGATGGTGC TTGTGGTCCC TATATTTCTT GTCGTTTTAC TGTGCTGTCT AATGCTGATC 
GCCTACCTCT GGTCTGAAGT ACAAGAAGTA GTATCTCCAC CGAGTTCATC AGAGTCTTCG 
TCTTCATCAT CCTGGTCAGA CTCTGACTCT CAGTGA