| Gene Symbol | Dock1 |
| Entrez Gene ID | 330662 |
| Full Name | dedicator of cytokinesis 1 |
| Synonyms | 9130006G06Rik,AI854900,D630004B07Rik,b2b3190Clo |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
The following Dock1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Dock1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu21588 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001033420.2 | |
| Accession Version | NM_001033420.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5598bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-04 | |
| Organism | Mus musculus(house mouse) | |
| Product | dedicator of cytokinesis protein 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC129300.3, AC100208.16, AC127574.3, AC136515.3 and AC136641.3. On Nov 17, 2006 this sequence version replaced NM_001033420.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001028592.1 |
| CDS | 113..5710 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001033420.2 |
1 | ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu39730 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006507965.3 | |
| Accession Version | XM_006507965.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 5661bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-06-21 | |
| Organism | Mus musculus(house mouse) | |
| Product | dedicator of cytokinesis protein 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507965.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006508028.1 |
| CDS | 195..5855 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006507965.3 |
1 | ATGACGCGCT GGGTCCCCAC CAAGCGAGAG GAGAAGTACG GCGTGGCCTT TTACAACTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1. |
Global genetic analysis in mice unveils central role for cilia in congenital heart disease. |
Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling. |
Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. |
The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo. |
