S100P cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	S100P
Entrez Gene ID	6286
Full Name	S100 calcium binding protein P
Synonyms	MIG9
General protein information	Preferred Names S100 calcium binding protein P Names protein S100-P migration-inducing gene 9 protein protein S100-E
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p16.1
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008].
Disorder MIM:	600614

mRNA and Protein(s)

mRNA	Protein	Name
NM_005980.3	NP_005971.1	protein S100-P
NM_005980.2	NP_005971.1	protein S100-P

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	S100P	XP_003310290.1
	S100P	XP_001091876.1
Canis lupus familiaris (dog)	S100P	XP_852856.2
Xenopus tropicalis (tropical clawed frog)	s100p	XP_002938306.1
Homo sapiens (human)	S100P	NP_005971.1

Gene Ontology
Bibliography

Related articles in PubMed

S100P in Duodenal Fluid Is a Useful Diagnostic Marker for Pancreatic Ductal Adenocarcinoma.
Matsunaga T, Ohtsuka T, Asano K, Kimura H, Ohuchida K, Kitada H, Ideno N, Mori Y, Tokunaga S, Oda Y, Guha S, Raimondo M, Nakamura M, Tanaka M
Pancreas46(10)1288-1295(2017 Nov/Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

activation of tissue plasminogen activator via the C-terminal lysine of S100P contributes to the enhancement of cell invasion by S100P and thus potentially to its metastasis-promoting activity.
Title: Activation of tissue plasminogen activator by metastasis-inducing S100P protein.

Novel positive feedback loop between Trx-1 and S100P promotes colorectal cancer invasion and metastasis.
Title: Thioredoxin-1 promotes colorectal cancer invasion and metastasis through crosstalk with S100P.

We established a novel quantitative analysis for the S100P protein in EUS-FNA samples which, when combined with EUS-FNA cytology, could provide promising results for the reliable diagnosis of pancreatic adenocarcinoma (PCA)
Title: Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma.

This study reveals significant association between blood-based decreased S100P methylation and Breast cancer (BC), and provides another proof for the application of altered DNA methylation signatures from blood cells as potential markers for the detection of BC, especially for the early stage.
Title: The association between breast cancer and S100P methylation in peripheral blood by multicenter case-control studies.

An S100P-positive biliary epithelial field is a preinvasive intraepithelial neoplasm in nodular-sclerosing cholangiocarcinoma.
Title: An S100P-positive biliary epithelial field is a preinvasive intraepithelial neoplasm in nodular-sclerosing cholangiocarcinoma.

The following S100P gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S100P cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu13068	NM_005980.2 Latest version!	Homo sapiens S100 calcium binding protein P (S100P), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu106840	NM_005980.3 Latest version!	Homo sapiens S100 calcium binding protein P (S100P), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

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2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

S100P ( NM_005980.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_005971.1 Homo sapiens S100 calcium binding protein P (S100P), mRNA.

Price & Availability↑

CloneID	OHu13068
Clone ID Related Accession (Same CDS sequence)	NM_005980.2
Accession Version	NM_005980.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 288bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-17
Organism	Homo sapiens(human)
Product	protein S100-P
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI259919.1, X65614.1 and AI202505.1. On Mar 30, 2004 this sequence version replaced NM_005980.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI259919.1, BE536069.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACGGAAC TAGAGACAGC CATGGGCATG ATCATAGACG TCTTTTCCCG ATATTCGGGC 
AGCGAGGGCA GCACGCAGAC CCTGACCAAG GGGGAGCTCA AGGTGCTGAT GGAGAAGGAG 
CTACCAGGCT TCCTGCAGAG TGGAAAAGAC AAGGATGCCG TGGATAAATT GCTCAAGGAC 
CTGGACGCCA ATGGAGATGC CCAGGTGGAC TTCAGTGAGT TCATCGTGTT CGTGGCTGCA 
ATCACGTCTG CCTGTCACAA GTACTTTGAG AAGGCAGGAC TCAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005971.1
CDS	95..382
Translation	MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAITSACHKYFEKAGLK

Target ORF information:

RefSeq Version	NM_005980.2
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein P (S100P), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005980.2

ORF Insert Sequence:

ATGACGGAAC TAGAGACAGC CATGGGCATG ATCATAGACG TCTTTTCCCG ATATTCGGGC 
AGCGAGGGCA GCACGCAGAC CCTGACCAAG GGGGAGCTCA AGGTGCTGAT GGAGAAGGAG 
CTACCAGGCT TCCTGCAGAG TGGAAAAGAC AAGGATGCCG TGGATAAATT GCTCAAGGAC 
CTGGACGCCA ATGGAGATGC CCAGGTGGAC TTCAGTGAGT TCATCGTGTT CGTGGCTGCA 
ATCACGTCTG CCTGTCACAA GTACTTTGAG AAGGCAGGAC TCAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

S100P ( NM_005980.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005971.1 Homo sapiens S100 calcium binding protein P (S100P), mRNA.

Price & Availability↑

CloneID	OHu106840
Clone ID Related Accession (Same CDS sequence)	NM_005980.3
Accession Version	NM_005980.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 288bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-15
Organism	Homo sapiens(human)
Product	protein S100-P
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC093323.3 and KF495696.1. On Aug 25, 2018 this sequence version replaced NM_005980.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM783029.1, BM854679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000296370.4/ ENSP00000296370.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGACGGAAC TAGAGACAGC CATGGGCATG ATCATAGACG TCTTTTCCCG ATATTCGGGC 
AGCGAGGGCA GCACGCAGAC CCTGACCAAG GGGGAGCTCA AGGTGCTGAT GGAGAAGGAG 
CTACCAGGCT TCCTGCAGAG TGGAAAAGAC AAGGATGCCG TGGATAAATT GCTCAAGGAC 
CTGGACGCCA ATGGAGATGC CCAGGTGGAC TTCAGTGAGT TCATAGTGTT CGTGGCTGCA 
ATCACGTCTG CCTGTCACAA GTACTTTGAG AAGGCAGGAC TCAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005971.1
CDS	56..343
Translation	MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVAAITSACHKYFEKAGLK

Target ORF information:

RefSeq Version	NM_005980.3
Organism	Homo sapiens(human)
Definition	Homo sapiens S100 calcium binding protein P (S100P), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005980.3

ORF Insert Sequence:

ATGACGGAAC TAGAGACAGC CATGGGCATG ATCATAGACG TCTTTTCCCG ATATTCGGGC 
AGCGAGGGCA GCACGCAGAC CCTGACCAAG GGGGAGCTCA AGGTGCTGAT GGAGAAGGAG 
CTACCAGGCT TCCTGCAGAG TGGAAAAGAC AAGGATGCCG TGGATAAATT GCTCAAGGAC 
CTGGACGCCA ATGGAGATGC CCAGGTGGAC TTCAGTGAGT TCATAGTGTT CGTGGCTGCA 
ATCACGTCTG CCTGTCACAA GTACTTTGAG AAGGCAGGAC TCAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

S100P in Duodenal Fluid Is a Useful Diagnostic Marker for Pancreatic Ductal Adenocarcinoma.
Pancreas46(10)1288-1295(2017 Nov/Dec)
Matsunaga T,Ohtsuka T,Asano K,Kimura H,Ohuchida K,Kitada H,Ideno N,Mori Y,Tokunaga S,Oda Y,Guha S,Raimondo M,Nakamura M,Tanaka M

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S100P cDNA ORF clone, Homo sapiens(human)

Gene

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Related articles in PubMed

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Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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