| Gene Symbol | Megf8 |
| Entrez Gene ID | 114029 |
| Full Name | multiple EGF-like-domains 8 |
| Synonyms | Egfl4 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Megf8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Megf8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa12249 | |
| Clone ID Related Accession (Same CDS sequence) | NM_053628.2 | |
| Accession Version | NM_053628.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 8370bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-06-07 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | multiple epidermal growth factor-like domains protein 8 precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC121639.5. On Sep 11, 2014 this sequence version replaced NM_053628.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments and orthologous data. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCCTTGG GCGGAGCTCT GGCCGCGGCC CTTGCACTGG CCTTCGCTGT GCTGGGGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_446080.1 |
| CDS | 344..8713 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_053628.2 |
1 | ATGGCCTTGG GCGGAGCTCT GGCCGCGGCC CTTGCACTGG CCTTCGCTGT GCTGGGGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa22369 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006228364.3 | |
| Accession Version | XM_006228364.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 8361bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | multiple epidermal growth factor-like domains protein 8 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228364.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCCTTGG GCGGAGCTCT GGCCGCGGCC CTTGCACTGG CCTTCGCTGT GCTGGGGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006228426.1 |
| CDS | 707..9067 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006228364.3 |
1 | ATGGCCTTGG GCGGAGCTCT GGCCGCGGCC CTTGCACTGG CCTTCGCTGT GCTGGGGCCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CRISPR Screens Uncover Genes that Regulate Target Cell Sensitivity to the Morphogen Sonic Hedgehog. |
Global genetic analysis in mice unveils central role for cilia in congenital heart disease. |
MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons. |
Mutations in multidomain protein MEGF8 identify a Carpenter syndrome subtype associated with defective lateralization. |
Massively parallel sequencing identifies the gene Megf8 with ENU-induced mutation causing heterotaxy. |
