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Il2rg cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Il2rg
Entrez Gene ID 140924
Full Name interleukin 2 receptor subunit gamma
Synonyms Ab2-183,Cd132
General protein information
Preferred Names

interleukin 2 receptor subunit gamma

Names

cytokine receptor common subunit gamma
interleukin 2 receptor, gamma (severe combined immunodeficiency)
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

X

Xq22
Summary cytokine receptor which contributes to ligand binding and signal transduction [RGD, Feb 2006].

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_017601899.1 XP_017457388.1 cytokine receptor common subunit gamma isoform X1
NM_080889.1 NP_543165.1 cytokine receptor common subunit gamma precursor

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) Il2rg NP_543165.1
Gallus gallus (chicken) IL2RG NP_989858.1
Danio rerio (zebrafish) il2rgb NP_001116522.1
Pan troglodytes (chimpanzee) LOC101059843 XP_003954068.1
Canis lupus familiaris (dog) IL2RG NP_001003201.1
IL2RG NP_001030606.1
Homo sapiens (human) IL2RG NP_000197.1
Mus musculus (house mouse) Il2rg NP_038591.1
Danio rerio (zebrafish) il2rga NP_001121743.1
Xenopus tropicalis (tropical clawed frog) LOC100492995 XP_002934932.1
Bos taurus (cattle) IL2RG NP_776784.1

Gene Ontology


Bibliography

Related articles in PubMed

Conditionals by inversion provide a universal method for the generation of conditional alleles.
Economides AN, Frendewey D, Yang P, Dominguez MG, Dore AT, Lobov IB, Persaud T, Rojas J, McClain J, Lengyel P, Droguett G, Chernomorsky R, Stevens S, Auerbach W, Dechiara TM, Pouyemirou W, Cruz JM Jr, Feeley K, Mellis IA, Yasenchack J, Hatsell SJ, Xie L, Latres E, Huang L, Zhang Y, Pefanis E, Skokos D, Deckelbaum RA, Croll SD, Davis S, Valenzuela DM, Gale NW, Murphy AJ, Yancopoulos GD
Proceedings of the National Academy of Sciences of the United States of America110(34)E3179-88(2013 Aug)

Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)

Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.
Mashimo T, Takizawa A, Voigt B, Yoshimi K, Hiai H, Kuramoto T, Serikawa T
PloS one5(1)e8870(2010 Jan)

E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene.
Jia J, Dai M, Zhuang Y
European journal of immunology38(10)2806-20(2008 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain
Title: Structural basis for binding multiple ligands by the common cytokine receptor gamma-chain.

The following Il2rg gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il2rg cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa00232 NM_080889.1
Latest version!		 Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
ORa62996 XM_017601899.1
Latest version!		 Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa00232
Clone ID Related Accession (Same CDS sequence) NM_080889.1
Accession Version NM_080889.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1107bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-04-18
Organism Rattus norvegicus(Norway rat)
Product cytokine receptor common subunit gamma precursor
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079343.1. On Apr 19, 2005 this sequence version replaced XM_343800.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079343.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTGTACACA 
TTTCGGGTTC GGAGCCGCTT TAACCCGATC TGTGGAAGTA CTCAACAGTG GAGTAAATGG 
AGCCAACCAA TCCACTGGGG GAGCCATACT GCAGAGGAGA ATCCTTCCTT GTTTGCACTG 
GAAGCTGTGC TTATCCCTGT TGGCACCATG GGGTTGATTA TTACCCTGAT CTTTGTGTAC 
TGTTGGTTGG AACGAATGCC TCGAATTCCC GCCATCAAGA ATCTAGAGGA TCTGGTTACT 
GAATACCATG GGAACTTTTC GGCCTGGAGT GGTGTGTCTA AAGGGCTGAC TGAGAGTCTG 
CAGCCAGACT ACAGTGAACG GTTCTGCCAC GTCAGTGAGA TTCCCCCGAA AGGAGGAGCC 
CTAGGAGAGG GGCCTGGAGG CTCTCCTTGC AGCCTTCATA GCCCTTACTG GCCTCCCCCA 
TGTTATTCTC TGAAGCCTGA AGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_543165.1
CDS15..1121
Translation

Target ORF information:

RefSeq Version NM_080889.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_080889.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTGTACACA 
TTTCGGGTTC GGAGCCGCTT TAACCCGATC TGTGGAAGTA CTCAACAGTG GAGTAAATGG 
AGCCAACCAA TCCACTGGGG GAGCCATACT GCAGAGGAGA ATCCTTCCTT GTTTGCACTG 
GAAGCTGTGC TTATCCCTGT TGGCACCATG GGGTTGATTA TTACCCTGAT CTTTGTGTAC 
TGTTGGTTGG AACGAATGCC TCGAATTCCC GCCATCAAGA ATCTAGAGGA TCTGGTTACT 
GAATACCATG GGAACTTTTC GGCCTGGAGT GGTGTGTCTA AAGGGCTGAC TGAGAGTCTG 
CAGCCAGACT ACAGTGAACG GTTCTGCCAC GTCAGTGAGA TTCCCCCGAA AGGAGGAGCC 
CTAGGAGAGG GGCCTGGAGG CTCTCCTTGC AGCCTTCATA GCCCTTACTG GCCTCCCCCA 
TGTTATTCTC TGAAGCCTGA AGCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa62996
Clone ID Related Accession (Same CDS sequence) XM_017601899.1
Accession Version XM_017601899.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 798bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product cytokine receptor common subunit gamma isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005120.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTAGAATCC 
TTCCTTGTTT GCACTGGAAG CTGTGCTTAT CCCTGTTGGC ACCATGGGGT TGATTATTAC 
CCTGATCTTT GTGTACTGTT GGTTGGAACG AATGCCTCGA ATTCCCGCCA TCAAGAATCT 
AGAGGATCTG GTTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017457388.1
CDS55..852
Translation

Target ORF information:

RefSeq Version XM_017601899.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus interleukin 2 receptor subunit gamma (Il2rg), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017601899.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
ATGTTGAAAC CATTATTGCC ATCTAGATCC TTCTTACTCC TTCAGCTGCT TCTGCTGAGG 
GTAGGGTGGA GCTCCAAGGT CCTCATGTCC AGTGGGAATG AAGACACCAA ATCTGATCTC 
TTGCTGACTT CTATGGACCT TAAACATCTC AGTGTTCCTA CTCTGCCCCT CCCAGAGGTT 
CAATGCTTTG TGTTCAATGT CGAGTATATG AATTGCACTT GGAATAGCAG TTCTGAGCCT 
CAGCCGACCA ACCTCACTAT GCACTATAGG TACAAGGGAT CTGATAATAA TACATTCCAG 
GAGTGCAGCC ACTATCTGTT CTCAAAAGAG ATTACTTCTG GCTGTCAGAT ACAAAAAGAA 
GATATCCAGC TCTACCAGAC ATTTGTTGTC CAGCTTCAGG ACCCCCAGAA ACCCCAGAGG 
CGAGCCGAAC AGAAGCTAAA CCTACAGAAT CTTGTGATCC CATGGGCTCC AGAGAATCTA 
ACACTTTATA ACCTGAGTGA ATCTCAGGTA GAACTGAGGT GGAAAAGCAG ATACATAGAA 
CGCTGTTTAC AATACTTGGT GCAGTACCGG AGCAACCGAG ATCGAAGCTG GACGGAACAA 
ATAGTGGATC ATGAGCCTAG ATTCTCCCTG CCTAGTGTGG ATGAACAGAA GCTAGAATCC 
TTCCTTGTTT GCACTGGAAG CTGTGCTTAT CCCTGTTGGC ACCATGGGGT TGATTATTAC 
CCTGATCTTT GTGTACTGTT GGTTGGAACG AATGCCTCGA ATTCCCGCCA TCAAGAATCT 
AGAGGATCTG GTTACTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Conditionals by inversion provide a universal method for the generation of conditional alleles.
Proceedings of the National Academy of Sciences of the United States of America110(34)E3179-88(2013 Aug)
Economides AN,Frendewey D,Yang P,Dominguez MG,Dore AT,Lobov IB,Persaud T,Rojas J,McClain J,Lengyel P,Droguett G,Chernomorsky R,Stevens S,Auerbach W,Dechiara TM,Pouyemirou W,Cruz JM Jr,Feeley K,Mellis IA,Yasenchack J,Hatsell SJ,Xie L,Latres E,Huang L,Zhang Y,Pefanis E,Skokos D,Deckelbaum RA,Croll SD,Davis S,Valenzuela DM,Gale NW,Murphy AJ,Yancopoulos GD


book

Defining the membrane proteome of NK cells.
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Ghosh D,Lippert D,Krokhin O,Cortens JP,Wilkins JA


book

Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases.
PloS one5(1)e8870(2010 Jan)
Mashimo T,Takizawa A,Voigt B,Yoshimi K,Hiai H,Kuramoto T,Serikawa T


book

E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene.
European journal of immunology38(10)2806-20(2008 Oct)
Jia J,Dai M,Zhuang Y