Gene Symbol | Crkl |
Entrez Gene ID | 287942 |
Full Name | v-crk avian sarcoma virus CT10 oncogene homolog-like |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Crkl cDNA ORF clone
Gene Symbol | Crkl |
Entrez Gene ID | 287942 |
Full Name | v-crk avian sarcoma virus CT10 oncogene homolog-like |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001008284.1 | NP_001008285.1 | crk-like protein |
CRKL | XP_001086123.1 | |
Gallus gallus (chicken) | CRKL | XP_415233.1 |
Pan troglodytes (chimpanzee) | CRKL | XP_525530.2 |
Canis lupus familiaris (dog) | CRKL | XP_849949.1 |
Xenopus tropicalis (tropical clawed frog) | crkl | NP_989060.1 |
Mus musculus (house mouse) | Crkl | NP_031790.2 |
Homo sapiens (human) | CRKL | NP_005198.1 |
Rattus norvegicus (Norway rat) | Crkl | NP_001008285.1 |
Rattus norvegicus (Norway rat) | LOC100911248 | XP_003751143.1 |
Danio rerio (zebrafish) | crkl | NP_998703.1 |
Murine model indicates 22q11.2 signaling adaptor
Haller M, Mo Q, Imamoto A, Lamb DJ
Proceedings of the National Academy of Sciences of the United States of America114(19)4981-4986(2017 May)
Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation.
Hallock PT, Chin S, Blais S, Neubert TA, Glass DJ
Molecular and cellular biology36(2)262-70(2015 Nov)
CRK proteins selectively regulate T cell migration into inflamed tissues.
Huang Y, Clarke F, Karimi M, Roy NH, Williamson EK, Okumura M, Mochizuki K, Chen EJ, Park TJ, Debes GF, Zhang Y, Curran T, Kambayashi T, Burkhardt JK
The Journal of clinical investigation125(3)1019-32(2015 Mar)
Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation.
Racedo SE, McDonald-McGinn DM, Chung JH, Goldmuntz E, Zackai E, Emanuel BS, Zhou B, Funke B, Morrow BE
American journal of human genetics96(2)235-44(2015 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Crkl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Crkl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa34495 | |
Clone ID Related Accession (Same CDS sequence) | NM_001008284.1 | |
Accession Version | NM_001008284.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 912bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | crk-like protein | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085865.1. On Dec 16, 2004 this sequence version replaced XM_221260.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC085865.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCCTCCG CCAGGTTTGA TTCTTCAGAC CGTTCTGCCT GGTACATGGG GCCAGTGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001008285.1 |
CDS | 483..1394 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001008284.1 |
1 | ATGTCCTCCG CCAGGTTTGA TTCTTCAGAC CGTTCTGCCT GGTACATGGG GCCAGTGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Murine model indicates 22q11.2 signaling adaptor |
Sorbs1 and -2 Interact with CrkL and Are Required for Acetylcholine Receptor Cluster Formation. |
CRK proteins selectively regulate T cell migration into inflamed tissues. |
Mouse and human CRKL is dosage sensitive for cardiac outflow tract formation. |