Gene Symbol | Hcls1 |
Entrez Gene ID | 288077 |
Full Name | hematopoietic cell specific Lyn substrate 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Hcls1 cDNA ORF clone
Gene Symbol | Hcls1 |
Entrez Gene ID | 288077 |
Full Name | hematopoietic cell specific Lyn substrate 1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001011898.1 | NP_001011898.1 | hematopoietic lineage cell-specific protein |
Homo sapiens (human) | HCLS1 | NP_005326.2 |
Mus musculus (house mouse) | Hcls1 | NP_032251.2 |
Rattus norvegicus (Norway rat) | Hcls1 | NP_001011898.1 |
Bos taurus (cattle) | HCLS1 | NP_001030229.1 |
Gallus gallus (chicken) | HCLS1 | NP_001026572.1 |
Pan troglodytes (chimpanzee) | HCLS1 | XP_516684.2 |
HCLS1 | XP_001111514.1 | |
Canis lupus familiaris (dog) | HCLS1 | XP_005639607.1 |
Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis.
Skokowa J, Klimiankou M, Klimenkova O, Lan D, Gupta K, Hussein K, Carrizosa E, Kusnetsova I, Li Z, Sustmann C, Ganser A, Zeidler C, Kreipe HH, Burkhardt J, Grosschedl R, Welte K
Nature medicine18(10)1550-9(2012 Oct)
Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation.
Samuels AL, Klinken SP, Ingley E
Blood113(16)3845-56(2009 Apr)
HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells.
Ingley E, Sarna MK, Beaumont JG, Tilbrook PA, Tsai S, Takemoto Y, Williams JH, Klinken SP
The Journal of biological chemistry275(11)7887-93(2000 Mar)
Examining the specificity of Src homology 3 domain--ligand interactions with alkaline phosphatase fusion proteins.
Yamabhai M, Kay BK
Analytical biochemistry247(1)143-51(1997 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Hcls1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hcls1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa01463 | |
Clone ID Related Accession (Same CDS sequence) | NM_001011898.1 | |
Accession Version | NM_001011898.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | hematopoietic lineage cell-specific protein | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079081.1. On Feb 11, 2005 this sequence version replaced XM_221421.2. ##Evidence-Data-START## Transcript exon combination :: BC079081.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTGGAAGT CTGTAGTGGG GCACAATGTA TCGGTTTCCG TGGAGACCCA GGGTGATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001011898.1 |
CDS | 32..1462 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001011898.1 |
1 | ATGTGGAAGT CTGTAGTGGG GCACAATGTA TCGGTTTCCG TGGAGACCCA GGGTGATGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis. |
Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. |
HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells. |
Examining the specificity of Src homology 3 domain--ligand interactions with alkaline phosphatase fusion proteins. |