| Gene Symbol | Numbl |
| Entrez Gene ID | 292732 |
| Full Name | NUMB-like, endocytic adaptor protein |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Numbl gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Numbl cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa08693 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001033888.1 | |
| Accession Version | NM_001033888.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1854bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | numb-like protein | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AB210107.1. On Sep 30, 2005 this sequence version replaced XM_218360.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB210107.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTCCCGCA GCGCGGCGGC CAGCGGCGGA CCCAGGAGAC CTGATCAGCA TTTGCCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001029060.1 |
| CDS | 1..1854 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001033888.1 |
1 | ATGTCCCGCA GCGCGGCGGC CAGCGGCGGA CCCAGGAGAC CTGATCAGCA TTTGCCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa22474 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006228565.3 | |
| Accession Version | XM_006228565.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | numb-like protein isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228565.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGACTACCA GGTTTCCTAC TAGGGAGCCT GAGATGGAGG GGGCTGAAGA GGGGACCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006228627.1 |
| CDS | 3079..5004 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006228565.3 |
1 | ATGACTACCA GGTTTCCTAC TAGGGAGCCT GAGATGGAGG GGGCTGAAGA GGGGACCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa22475 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006228566.3 | |
| Accession Version | XM_006228566.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1923bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | numb-like protein isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228566.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGACTACCA GGTTTCCTAC TAGGGAGCCT GAGATGGAGG GGGCTGAAGA GGGGACCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006228628.1 |
| CDS | 3079..5001 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006228566.3 |
1 | ATGACTACCA GGTTTCCTAC TAGGGAGCCT GAGATGGAGG GGGCTGAAGA GGGGACCAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa22476 | |
| Clone ID Related Accession (Same CDS sequence) | XM_006228567.3 | |
| Accession Version | XM_006228567.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1845bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | numb-like protein isoform X3 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006228567.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTCCCGCA GCGCGGCGGC CAGCGGCGGA CCCAGGAGAC CTGATCAGCA TTTGCCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_006228629.1 |
| CDS | 208..2052 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_006228567.3 |
1 | ATGTCCCGCA GCGCGGCGGC CAGCGGCGGA CCCAGGAGAC CTGATCAGCA TTTGCCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Dynamic change of Numbl expression after sciatic nerve crush and its role in Schwann cell differentiation. |
Expression of Numb and Numb-like in the development of mammalian auditory sensory epithelium. |
NUMBL interacts with TRAF6 and promotes the degradation of TRAF6. |
NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation. |
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. |
