Gene Symbol | Orai2 |
Entrez Gene ID | 304592 |
Full Name | ORAI calcium release-activated calcium modulator 2 |
Synonyms | RGD1310213 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Orai2 cDNA ORF clone
gRNAs
Gene Symbol | Orai2 |
Entrez Gene ID | 304592 |
Full Name | ORAI calcium release-activated calcium modulator 2 |
Synonyms | RGD1310213 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017598356.1 | XP_017453845.1 | protein orai-2 isoform X1 |
NM_001170403.1 | NP_001163874.1 | protein orai-2 |
Pan troglodytes (chimpanzee) | ORAI2 | XP_001155376.2 |
ORAI2 | XP_001108554.2 | |
Rattus norvegicus (Norway rat) | Orai2 | NP_001163874.1 |
Bos taurus (cattle) | ORAI2 | NP_001178277.1 |
Mus musculus (house mouse) | Orai2 | NP_848866.2 |
Homo sapiens (human) | ORAI2 | NP_001119812.1 |
Gallus gallus (chicken) | ORAI2 | NP_001025881.1 |
Xenopus tropicalis (tropical clawed frog) | orai1 | NP_001096448.1 |
Canis lupus familiaris (dog) | ORAI2 | XP_850105.1 |
Danio rerio (zebrafish) | orai2 | NP_001159919.1 |
Orai-2 is localized on secretory granules and regulates antigen-evoked Ca?? mobilization and exocytosis in mast cells.
Ikeya M, Yamanoue K, Mochizuki Y, Konishi H, Tadokoro S, Tanaka M, Suzuki R, Hirashima N
Biochemical and biophysical research communications451(1)62-7(2014 Aug)
STIM proteins: dynamic calcium signal transducers.
Soboloff J, Rothberg BS, Madesh M, Gill DL
Nature reviews. Molecular cell biology13(9)549-65(2012 Sep)
STIM1 is necessary for store-operated calcium entry in turning growth cones.
Mitchell CB, Gasperini RJ, Small DH, Foa L
Journal of neurochemistry122(6)1155-66(2012 Sep)
Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry.
Takahashi Y, Murakami M, Watanabe H, Hasegawa H, Ohba T, Munehisa Y, Nobori K, Ono K, Iijima T, Ito H
Biochemical and biophysical research communications356(1)45-52(2007 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Orai-2 is localized on secretory granules in mast cells.Orai-2 regulates degranulation by affecting Ca release from Ca store.
Title: Orai-2 is localized on secretory granules and regulates antigen-evoked Ca?? mobilization and exocytosis in mast cells.
The following Orai2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Orai2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa06186 | |
Clone ID Related Accession (Same CDS sequence) | NM_001170403.1 | |
Accession Version | NM_001170403.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 942bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-28 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein orai-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EU644750.1, BC158835.1 and AABR07035819.1. On or before Dec 19, 2009 this sequence version replaced XM_222288.4, XM_001077075.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: EU644750.1, BC158835.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGTCACG TGACGGCGGC GCAGCGTTGC CTAGGCAGCG GCTGCGGGCG GAAAGAGGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001163874.1 |
CDS | 1..942 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGGTCACG TGACGGCGGC GCAGCGTTGC CTAGGCAGCG GCTGCGGGCG GAAAGAGGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa57830 | |
Clone ID Related Accession (Same CDS sequence) | XM_017598356.1 | |
Accession Version | XM_017598356.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | protein orai-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005111.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGGAGG TGCAGCTGGA GACCAAGTAC CAGTACCCTC AGCCCCTGCT CATCGCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017453845.1 |
CDS | 92..613 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGTGGAGG TGCAGCTGGA GACCAAGTAC CAGTACCCTC AGCCCCTGCT CATCGCCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Orai-2 is localized on secretory granules and regulates antigen-evoked Ca?? mobilization and exocytosis in mast cells. |
STIM proteins: dynamic calcium signal transducers. |
STIM1 is necessary for store-operated calcium entry in turning growth cones. |
Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry. |