Zmpste24 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Gene Symbol	Zmpste24
Entrez Gene ID	313564
Full Name	zinc metallopeptidase STE24
General protein information	Preferred Names zinc metallopeptidase STE24 Names CAAX prenyl protease 1 homolog zinc metallopeptidase, STE24 homolog zinc metalloproteinase, STE24 homolog
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 5 Map Location: 5q36

mRNA and Protein(s)

mRNA Protein Name

NM_001107974.1 NP_001101444.1 CAAX prenyl protease 1 homolog

XM_017593398.1 XP_017448887.1 CAAX prenyl protease 1 homolog isoform X1
Pathways from BioSystems

mRNA	Protein	Name
NM_001107974.1	NP_001101444.1	CAAX prenyl protease 1 homolog
XM_017593398.1	XP_017448887.1	CAAX prenyl protease 1 homolog isoform X1

Homologies

Pan troglodytes (chimpanzee)	ZMPSTE24	XP_513352.2
Mus musculus (house mouse)	Zmpste24	NP_766288.1
Rattus norvegicus (Norway rat)	Zmpste24	NP_001101444.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004470	XP_313769.4
Arabidopsis thaliana (thale cress)	ATSTE24	NP_567212.1
Xenopus tropicalis (tropical clawed frog)	zmpste24	NP_001017255.1
Bos taurus (cattle)	ZMPSTE24	NP_001179857.1
Danio rerio (zebrafish)	zmpste24	NP_956186.1
Saccharomyces cerevisiae (baker's yeast)	STE24	NP_012651.1
Oryza sativa (rice)	Os02g0680400	NP_001047739.1
Schizosaccharomyces pombe (fission yeast)	SPAC3H1.05	NP_593547.1
Magnaporthe oryzae (rice blast fungus)	MGG_06951	XP_003709694.1
Neurospora crassa	NCU03637	XP_961364.2
Homo sapiens (human)	ZMPSTE24	NP_005848.2
	ZMPSTE24	XP_001082852.1
Gallus gallus (chicken)	ZMPSTE24	XP_417720.1
Canis lupus familiaris (dog)	ZMPSTE24	XP_539577.3
Drosophila melanogaster (fruit fly)	ste24a	NP_611175.1
Caenorhabditis elegans (roundworm)	fce-1	NP_492582.1
Kluyveromyces lactis	KLLA0D10846g	XP_453545.1

Gene Ontology
Bibliography

Related articles in PubMed

ZMPSTE24 defends against influenza and other pathogenic viruses.
Fu B, Wang L, Li S, Dorf ME
The Journal of experimental medicine214(4)919-929(2017 Apr)

Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations.
Rivera-Torres J, Calvo CJ, Llach A, Guzm?n-Mart?nez G, Caballero R, Gonz?lez-G?mez C, Jim?nez-Borreguero LJ, Guadix JA, Osorio FG, L?pez-Ot?n C, Herraiz-Mart?nez A, Cabello N, Vallmitjana A, Ben?tez R, Gordon LB, Jalife J, P?rez-Pomares JM, Tamargo J, Delp?n E, Hove-Madsen L, Filgueiras-Rama D, Andr?s V
Proceedings of the National Academy of Sciences of the United States of America113(46)E7250-E7259(2016 Nov)

Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.
Wang M, Fu Y, Gao C, Jia Y, Huang Y, Liu L, Wang X, Wang W, Kong W
Biochemical and biophysical research communications478(2)1006-13(2016 09)

Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.
Ibrahim MX, Sayin VI, Akula MK, Liu M, Fong LG, Young SG, Bergo MO
Science (New York, N.Y.)340(6138)1330-3(2013 Jun)

Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model.
Liu B, Wang Z, Zhang L, Ghosh S, Zheng H, Zhou Z
Nature communications41868(2013)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Zmpste24 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Zmpste24 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
ORa06399	NM_001107974.1 Latest version!	Rattus norvegicus zinc metallopeptidase STE24 (Zmpste24), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$279.30 $399.00
ORa61235	XM_017593398.1 Latest version!	Rattus norvegicus zinc metallopeptidase STE24 (Zmpste24), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

ORF Online Only Promotion

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5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Zmpste24 ( NM_001107974.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001101444.1 Rattus norvegicus zinc metallopeptidase STE24 (Zmpste24), mRNA.

Price & Availability↑

CloneID	ORa06399
Clone ID Related Accession (Same CDS sequence)	NM_001107974.1
Accession Version	NM_001107974.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-18
Organism	Rattus norvegicus(Norway rat)
Product	CAAX prenyl protease 1 homolog
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473968.1. On or before Oct 4, 2007 this sequence version replaced XM_001053840.1, XM_233483.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGGGGATGT GGGCATCGGT GGACGCTATG TGGGACTTCC CTGCGGAGAA GCGAATCTTC 
GGGGCGGTGT TGCTCTTTTC CTGGACCGTG TATCTTTGGG AGACCTTCCT AGCACAGCGG 
CAGAGAAGGA TATACAAAAC AACGACTCAT GTACCACCAG AGTTAGAACA GATCATGGAT 
TCGGACACAT TTGAGAAATC ACGACTGTAT CAACTGGATA AAAGTACATT CAGCTTCTGG 
TCAGGACTCT ATTCAGAGGT GGAAGGCACT TTTATTCTTC TCTTTGGAGG AATCCCTTAC 
CTCTGGAGAC TTTCTGGACG GTTCTGTAGT TCTGCTGGCT TCGGACCAGA ATATGAGATC 
ATTCAGTCGT TGGTGTTCCT GCTGTTGGCT ACACTCTTCA GTGCACTGAC TGGCTTGCCA 
TGGAGTCTGT ACAATACTTT CGTGATAGAA GAAAAGCATG GCTTCAATCA CCAGACTTTG 
GAGTTTTTTA TGAAAGATGC AATCAAAAAA TTTATTGTGA CTCAGTGTAT TTTATTGCCT 
GTGTCTTCCC TTCTGCTTTA CATTATTAAA ATCGGAGGTG ACTACTTTTT TATCTATGCC 
TGGCTGTTCA CATTAGTTGT TTCTCTGGTT CTTGTCACAA TTTATGCTGA TTATATTGCC 
CCTTTGTTTG ACAAGTTCAC ACCTCTACCG GAGGGGAAAC TTAAGCAGGA AATCGAAGTG 
ATGGCGAAGA GTATTGACTT CCCCCTGACT AAGGTGTATG TCGTTGAAGG ATCTAAGCGC 
TCCTCCCACA GCAATGCTTA CTTTTATGGC TTCTTCAAGA ACAAGAGAAT AGTTTTGTTT 
GACACTCTAC TAGAAGAGTA CTCTGTACCA AACAAAGACA ACCAGGAGGA GCCTGGCCTG 
GAGCCCCGCA ATGAAGGCGA AGGGGACAGT GAAGAAGTAA AGTCTAAAGT GAAAAATAAG 
AAACAAGGAT GTAAAAATGA GGAGGTACTA GCTGTACTTG GCCATGAACT GGGGCACTGG 
AAGTTGGGAC ACACAGTAAA AAATATCATT ATTAGTCAGA TGAATTCTTT CCTGTGTTTT 
TTCTTGTTTG CTGTATTAAT TGGTCGAAGG GAACTTTTTG CCGCCTTTGG TTTTTATGAC 
AGCCAACCCA CTCTGATCGG ACTTTTGATC ATCTTTCAGT TTATTTTCTC ACCTTACAAT 
GAGGTTCTGT CTTTCTGCCT AACAGTCCTG AGCCGCAGAT TTGAATTTCA AGCCGACGCT 
TTTGCCAAGA AACTTGGGAA GGCTAAAGAC TTATATTCTG CTTTGATCAA GCTAAACAAA 
GATAACCTGG GCTTCCCAGT CTCTGACTGG CTGTTCTCAA CATGGCACTA TTCTCACCCT 
CCGCTTCTGG AGAGGCTTCA GGCTCTGAAA AATGCAAAAC GAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001101444.1
CDS	322..1749
Translation	MGMWASVDAMWDFPAEKRIFGAVLLFSWTVYLWETFLAQRQRRIYKTTTHVPPELEQIMDSDTFEKSRLYQLDKSTFSFWSGLYSEVEGTFILLFGGIPYLWRLSGRFCSSAGFGPEYEIIQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNHQTLEFFMKDAIKKFIVTQCILLPVSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKQEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFYGFFKNKRIVLFDTLLEEYSVPNKDNQEEPGLEPRNEGEGDSEEVKSKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRRELFAAFGFYDSQPTLIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSTWHYSHPPLLERLQALKNAKRD

Target ORF information:

RefSeq Version	NM_001107974.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc metallopeptidase STE24 (Zmpste24), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107974.1

ORF Insert Sequence:

ATGGGGATGT GGGCATCGGT GGACGCTATG TGGGACTTCC CTGCGGAGAA GCGAATCTTC 
GGGGCGGTGT TGCTCTTTTC CTGGACCGTG TATCTTTGGG AGACCTTCCT AGCACAGCGG 
CAGAGAAGGA TATACAAAAC AACGACTCAT GTACCACCAG AGTTAGAACA GATCATGGAT 
TCGGACACAT TTGAGAAATC ACGACTGTAT CAACTGGATA AAAGTACATT CAGCTTCTGG 
TCAGGACTCT ATTCAGAGGT GGAAGGCACT TTTATTCTTC TCTTTGGAGG AATCCCTTAC 
CTCTGGAGAC TTTCTGGACG GTTCTGTAGT TCTGCTGGCT TCGGACCAGA ATATGAGATC 
ATTCAGTCGT TGGTGTTCCT GCTGTTGGCT ACACTCTTCA GTGCACTGAC TGGCTTGCCA 
TGGAGTCTGT ACAATACTTT CGTGATAGAA GAAAAGCATG GCTTCAATCA CCAGACTTTG 
GAGTTTTTTA TGAAAGATGC AATCAAAAAA TTTATTGTGA CTCAGTGTAT TTTATTGCCT 
GTGTCTTCCC TTCTGCTTTA CATTATTAAA ATCGGAGGTG ACTACTTTTT TATCTATGCC 
TGGCTGTTCA CATTAGTTGT TTCTCTGGTT CTTGTCACAA TTTATGCTGA TTATATTGCC 
CCTTTGTTTG ACAAGTTCAC ACCTCTACCG GAGGGGAAAC TTAAGCAGGA AATCGAAGTG 
ATGGCGAAGA GTATTGACTT CCCCCTGACT AAGGTGTATG TCGTTGAAGG ATCTAAGCGC 
TCCTCCCACA GCAATGCTTA CTTTTATGGC TTCTTCAAGA ACAAGAGAAT AGTTTTGTTT 
GACACTCTAC TAGAAGAGTA CTCTGTACCA AACAAAGACA ACCAGGAGGA GCCTGGCCTG 
GAGCCCCGCA ATGAAGGCGA AGGGGACAGT GAAGAAGTAA AGTCTAAAGT GAAAAATAAG 
AAACAAGGAT GTAAAAATGA GGAGGTACTA GCTGTACTTG GCCATGAACT GGGGCACTGG 
AAGTTGGGAC ACACAGTAAA AAATATCATT ATTAGTCAGA TGAATTCTTT CCTGTGTTTT 
TTCTTGTTTG CTGTATTAAT TGGTCGAAGG GAACTTTTTG CCGCCTTTGG TTTTTATGAC 
AGCCAACCCA CTCTGATCGG ACTTTTGATC ATCTTTCAGT TTATTTTCTC ACCTTACAAT 
GAGGTTCTGT CTTTCTGCCT AACAGTCCTG AGCCGCAGAT TTGAATTTCA AGCCGACGCT 
TTTGCCAAGA AACTTGGGAA GGCTAAAGAC TTATATTCTG CTTTGATCAA GCTAAACAAA 
GATAACCTGG GCTTCCCAGT CTCTGACTGG CTGTTCTCAA CATGGCACTA TTCTCACCCT 
CCGCTTCTGG AGAGGCTTCA GGCTCTGAAA AATGCAAAAC GAGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Zmpste24 ( XM_017593398.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017448887.1 Rattus norvegicus zinc metallopeptidase STE24 (Zmpste24), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa61235
Clone ID Related Accession (Same CDS sequence)	XM_017593398.1
Accession Version	XM_017593398.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1281bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	CAAX prenyl protease 1 homolog isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGATGT GGGCATCGGT GGACGCTATG TGGGACTTCC CTGCGGAGAA GCGAATCTTC 
GGGGCGGTGT TGCTCTTTTC CTGGACCGTG TATCTTTGGG AGACCTTCCT AGCACAGCGG 
CAGTTTATTC TTCTCTTTGG AGGAATCCCT TACCTCTGGA GACTTTCTGG ACGGTTCTGT 
AGTTCTGCTG GCTTCGGACC AGAATATGAG ATCATTCAGT CGTTGGTGTT CCTGCTGTTG 
GCTACACTCT TCAGTGCACT GACTGGCTTG CCATGGAGTC TGTACAATAC TTTCGTGATA 
GAAGAAAAGC ATGGCTTCAA TCACCAGACT TTGGAGTTTT TTATGAAAGA TGCAATCAAA 
AAATTTATTG TGACTCAGTG TATTTTATTG CCTGTGTCTT CCCTTCTGCT TTACATTATT 
AAAATCGGAG GTGACTACTT TTTTATCTAT GCCTGGCTGT TCACATTAGT TGTTTCTCTG 
GTTCTTGTCA CAATTTATGC TGATTATATT GCCCCTTTGT TTGACAAGTT CACACCTCTA 
CCGGAGGGGA AACTTAAGCA GGAAATCGAA GTGATGGCGA AGAGTATTGA CTTCCCCCTG 
ACTAAGGTGT ATGTCGTTGA AGGATCTAAG CGCTCCTCCC ACAGCAATGC TTACTTTTAT 
GGCTTCTTCA AGAACAAGAG AATAGTTTTG TTTGACACTC TACTAGAAGA GTACTCTGTA 
CCAAACAAAG ACAACCAGGA GGAGCCTGGC CTGGAGCCCC GCAATGAAGG CGAAGGGGAC 
AGTGAAGAAG TAAAGTCTAA AGTGAAAAAT AAGAAACAAG GATGTAAAAA TGAGGAGGTA 
CTAGCTGTAC TTGGCCATGA ACTGGGGCAC TGGAAGTTGG GACACACAGT AAAAAATATC 
ATTATTAGTC AGATGAATTC TTTCCTGTGT TTTTTCTTGT TTGCTGTATT AATTGGTCGA 
AGGGAACTTT TTGCCGCCTT TGGTTTTTAT GACAGCCAAC CCACTCTGAT CGGACTTTTG 
ATCATCTTTC AGTTTATTTT CTCACCTTAC AATGAGGTTC TGTCTTTCTG CCTAACAGTC 
CTGAGCCGCA GATTTGAATT TCAAGCCGAC GCTTTTGCCA AGAAACTTGG GAAGGCTAAA 
GACTTATATT CTGCTTTGAT CAAGCTAAAC AAAGATAACC TGGGCTTCCC AGTCTCTGAC 
TGGCTGTTCT CAACATGGCA CTATTCTCAC CCTCCGCTTC TGGAGAGGCT TCAGGCTCTG 
AAAAATGCAA AACGAGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017448887.1
CDS	230..1510
Translation	MGMWASVDAMWDFPAEKRIFGAVLLFSWTVYLWETFLAQRQFILLFGGIPYLWRLSGRFCSSAGFGPEYEIIQSLVFLLLATLFSALTGLPWSLYNTFVIEEKHGFNHQTLEFFMKDAIKKFIVTQCILLPVSSLLLYIIKIGGDYFFIYAWLFTLVVSLVLVTIYADYIAPLFDKFTPLPEGKLKQEIEVMAKSIDFPLTKVYVVEGSKRSSHSNAYFYGFFKNKRIVLFDTLLEEYSVPNKDNQEEPGLEPRNEGEGDSEEVKSKVKNKKQGCKNEEVLAVLGHELGHWKLGHTVKNIIISQMNSFLCFFLFAVLIGRRELFAAFGFYDSQPTLIGLLIIFQFIFSPYNEVLSFCLTVLSRRFEFQADAFAKKLGKAKDLYSALIKLNKDNLGFPVSDWLFSTWHYSHPPLLERLQALKNAKRD

Target ORF information:

RefSeq Version	XM_017593398.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus zinc metallopeptidase STE24 (Zmpste24), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017593398.1

ORF Insert Sequence:

ATGGGGATGT GGGCATCGGT GGACGCTATG TGGGACTTCC CTGCGGAGAA GCGAATCTTC 
GGGGCGGTGT TGCTCTTTTC CTGGACCGTG TATCTTTGGG AGACCTTCCT AGCACAGCGG 
CAGTTTATTC TTCTCTTTGG AGGAATCCCT TACCTCTGGA GACTTTCTGG ACGGTTCTGT 
AGTTCTGCTG GCTTCGGACC AGAATATGAG ATCATTCAGT CGTTGGTGTT CCTGCTGTTG 
GCTACACTCT TCAGTGCACT GACTGGCTTG CCATGGAGTC TGTACAATAC TTTCGTGATA 
GAAGAAAAGC ATGGCTTCAA TCACCAGACT TTGGAGTTTT TTATGAAAGA TGCAATCAAA 
AAATTTATTG TGACTCAGTG TATTTTATTG CCTGTGTCTT CCCTTCTGCT TTACATTATT 
AAAATCGGAG GTGACTACTT TTTTATCTAT GCCTGGCTGT TCACATTAGT TGTTTCTCTG 
GTTCTTGTCA CAATTTATGC TGATTATATT GCCCCTTTGT TTGACAAGTT CACACCTCTA 
CCGGAGGGGA AACTTAAGCA GGAAATCGAA GTGATGGCGA AGAGTATTGA CTTCCCCCTG 
ACTAAGGTGT ATGTCGTTGA AGGATCTAAG CGCTCCTCCC ACAGCAATGC TTACTTTTAT 
GGCTTCTTCA AGAACAAGAG AATAGTTTTG TTTGACACTC TACTAGAAGA GTACTCTGTA 
CCAAACAAAG ACAACCAGGA GGAGCCTGGC CTGGAGCCCC GCAATGAAGG CGAAGGGGAC 
AGTGAAGAAG TAAAGTCTAA AGTGAAAAAT AAGAAACAAG GATGTAAAAA TGAGGAGGTA 
CTAGCTGTAC TTGGCCATGA ACTGGGGCAC TGGAAGTTGG GACACACAGT AAAAAATATC 
ATTATTAGTC AGATGAATTC TTTCCTGTGT TTTTTCTTGT TTGCTGTATT AATTGGTCGA 
AGGGAACTTT TTGCCGCCTT TGGTTTTTAT GACAGCCAAC CCACTCTGAT CGGACTTTTG 
ATCATCTTTC AGTTTATTTT CTCACCTTAC AATGAGGTTC TGTCTTTCTG CCTAACAGTC 
CTGAGCCGCA GATTTGAATT TCAAGCCGAC GCTTTTGCCA AGAAACTTGG GAAGGCTAAA 
GACTTATATT CTGCTTTGAT CAAGCTAAAC AAAGATAACC TGGGCTTCCC AGTCTCTGAC 
TGGCTGTTCT CAACATGGCA CTATTCTCAC CCTCCGCTTC TGGAGAGGCT TCAGGCTCTG 
AAAAATGCAA AACGAGACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ZMPSTE24 defends against influenza and other pathogenic viruses.
The Journal of experimental medicine214(4)919-929(2017 Apr)
Fu B,Wang L,Li S,Dorf ME

Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations.
Proceedings of the National Academy of Sciences of the United States of America113(46)E7250-E7259(2016 Nov)
Rivera-Torres J,Calvo CJ,Llach A,Guzm?n-Mart?nez G,Caballero R,Gonz?lez-G?mez C,Jim?nez-Borreguero LJ,Guadix JA,Osorio FG,L?pez-Ot?n C,Herraiz-Mart?nez A,Cabello N,Vallmitjana A,Ben?tez R,Gordon LB,Jalife J,P?rez-Pomares JM,Tamargo J,Delp?n E,Hove-Madsen L,Filgueiras-Rama D,Andr?s V

Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.
Biochemical and biophysical research communications478(2)1006-13(2016 09)
Wang M,Fu Y,Gao C,Jia Y,Huang Y,Liu L,Wang X,Wang W,Kong W

Targeting isoprenylcysteine methylation ameliorates disease in a mouse model of progeria.
Science (New York, N.Y.)340(6138)1330-3(2013 Jun)
Ibrahim MX,Sayin VI,Akula MK,Liu M,Fong LG,Young SG,Bergo MO

Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model.
Nature communications41868(2013)
Liu B,Wang Z,Zhang L,Ghosh S,Zheng H,Zhou Z

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Zmpste24 cDNA ORF clone, Rattus norvegicus(Norway rat)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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