Slc4a8 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	Slc4a8
Entrez Gene ID	315311
Full Name	solute carrier family 4 member 8
General protein information	Preferred Names solute carrier family 4 member 8 Names electroneutral sodium bicarbonate exchanger 1 Na-driven Cl-HCO3 exchanger NDCBE1-A Na-driven Cl-HCO3 exchanger NDCBE1-B Na-driven Cl-HCO3 exchanger NDCBE1-C electroneutral Na+-driven Cl-HCO3 exchanger k-NBC3 solute carrier family 4 (anion exchanger), member 8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 7 Map Location: 7q36
Summary	may act as a bicarbonate transporter [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
XM_017594897.1	XP_017450386.1	electroneutral sodium bicarbonate exchanger 1 isoform X1
XM_017594898.1	XP_017450387.1	electroneutral sodium bicarbonate exchanger 1 isoform X2
NM_001270794.1	NP_001257723.1	electroneutral sodium bicarbonate exchanger 1 isoform 2
NM_001270795.1	NP_001257724.1	electroneutral sodium bicarbonate exchanger 1 isoform 3
NM_199497.2	NP_955791.1	electroneutral sodium bicarbonate exchanger 1 isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SLC4A8	XP_005636865.1
Mus musculus (house mouse)	Slc4a8	NP_067505.2
Danio rerio (zebrafish)	slc4a8	XP_685666.5
Homo sapiens (human)	SLC4A8	NP_001035049.1
	SLC4A8	XP_001090180.1
Bos taurus (cattle)	SLC4A8	XP_002687339.3
Gallus gallus (chicken)	LOC425441	XP_004949806.1
Rattus norvegicus (Norway rat)	Slc4a8	NP_001257723.1
Xenopus tropicalis (tropical clawed frog)	slc4a8	XP_002933752.2

Gene Ontology
Bibliography

Related articles in PubMed

Effect of prediabetes on membrane bicarbonate transporters in testis and epididymis.
Bernardino RL, Martins AD, Socorro S, Alves MG, Oliveira PF
The Journal of membrane biology246(12)877-83(2013 Dec)

Immunocytochemical identification of electroneutral Na?-coupled HCO?? transporters in freshly dissociated mouse medullary raph? neurons.
Coley AA, Ruffin VA, Moss FJ, Hopfer U, Boron WF
Neuroscience246451-67(2013 Aug)

The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals.
Burette AC, Weinberg RJ, Sassani P, Abuladze N, Kao L, Kurtz I
The Journal of comparative neurology520(7)1481-92(2012 May)

The sodium-driven chloride/bicarbonate exchanger NDCBE in rat brain is upregulated by chronic metabolic acidosis.
Lee HJ, Park HJ, Lee S, Kim YH, Choi I
Brain research137713-20(2011 Mar)

Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNS.
Chen LM, Kelly ML, Parker MD, Bouyer P, Gill HS, Felie JM, Davis BA, Boron WF
Neuroscience153(1)162-74(2008 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These findings suggest that NDCBE can regulate glutamatergic transmission throughout the brain
Title: The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals.

The sodium-driven chloride/bicarbonate exchanger NDCBE is upregulated in multiple neurons in a cell type-specific manner.
Title: The sodium-driven chloride/bicarbonate exchanger NDCBE in rat brain is upregulated by chronic metabolic acidosis.

Results suggest that Na(+)-driven Cl(-)/HCO(3)(-) exchanger (NCBE) activity is inhibited by protein kinase A and depends on the integrity of the actin cytoskeleton within a multiprotein complex at the plasma membrane.
Title: Regulation of the rat brain Na+ -driven Cl-/HCO3 - exchanger involves protein kinase A and a multiprotein signaling complex.

The following Slc4a8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Slc4a8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa62027	XM_017594898.1 Latest version!	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
ORa62026	XM_017594897.1 Latest version!	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
ORa05379	NM_199497.2 Latest version!	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$783.30 $1119.00
ORa09808	NM_001270794.1 Latest version!	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
ORa09813	NM_001270795.1 Latest version!	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Slc4a8 ( XM_017594898.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450387.1 Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant X2, mRNA.

Price & Availability↑

CloneID	ORa62027
Clone ID Related Accession (Same CDS sequence)	XM_017594898.1
Accession Version	XM_017594898.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2736bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	electroneutral sodium bicarbonate exchanger 1 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGCACAA GCAGCATAGA GGAGATCTCA GACCTGATCC TGGACCAGCA GGAGCTGCTC 
CGGGACCTGA GCGACAGCGT GCGGGTTAAG GTGCGGGAAG CCTTGCTGAA GAAGCATCAC 
CATCAGAACG AGAAGAAGAG GAACAACCTC ATCCCCATCG TCCGCTCCTT TGCCGAGGTC 
GGCAAGAAGC AGTCTGACCC GCATTCCATG GACAGAGATG GGCAAACCGT GTCTCCTCAG 
TCTGCTCCAG CTACCAACCT TGAAGTGAAG AATGGTGTGA ACTGTGAACA CAGCCCTGTG 
GATCTAAGCA AGGCGGACCT CCATTTCATG AAAAAGATTC CCGCAGGGGC AGAGGCCTCC 
AATGTCCTGG TTGGCGAGGT GGACACTCTG GACCGGCCCA TCGTCGCTTT CGTGAGGCTC 
TCCCCGGCCG TGCTCCTCTC TGGACTGACA GAAGTGCCCA TCCCAACGAG GTTTTTGTTT 
ATCTTACTGG GTCCGGTAGG AAAAGGGCAG CAGTACCATG AGATTGGCAG ATCCATGGCC 
ACCATCATGA CGGATGAGAT TTTTCACGAT GTGGCGTATA AAGCGAAAGA ACGGGATGAT 
CTCCTGGCTG GGATCGATGA GTTCCTGGAT CAAGTGACGG TGCTCCCACC AGGGGAGTGG 
GACCCGTCCA TTAGAATTGA GCCACCCAAG AATGTCCCTT CCCAGGAAAA AAGGAAGATG 
CCTGGCGTTC CAAACGGAAA CATTTGCCAC GTAGAACCTG AGCCACATGG GGGACACAGC 
GGGCCGGAAC TTGAGCGGAC GGGGCGGCTG TTTGGGGGCT TGGTGCTGGA TGTCAAACGG 
AAGGCTCCCT GGTACTGGAG TGACTACCGG GATGCTCTCA GCTTACAGTG TCTGGCCTCC 
TTCCTGTTCC TGTACTGTGC CTGCATGTCG CCTGTTATCA CCTTCGGGGG ACTGCTGGGA 
GAAGCCACGG AAGGACGCAT AAGTGCAATC GAATCGTTGT TTGGAGCCTC CATGACGGGG 
ATTGCCTACT CTCTGTTTGC TGGGCAGCCT CTCACCATCC TGGGAAGCAC GGGCCCTGTG 
CTGGTGTTTG AAAAGATTTT GTTCAAATTC TGCAAGGACT ACGCCCTTTC ATACCTCTCC 
TTGCGTGCTT GTATCGGGCT GTGGACCGCC TTCCTGTGTA TTGTCCTGGT GGCGACTGAT 
GCCAGTTCCC TCGTCTGCTA CATTACCCGC TTCACCGAGG AAGCCTTTGC CTCCCTGATT 
TGCATTATTT TCATCTATGA AGCCATAGAA AAGCTGATTC ACCTGGCCGA GACCTACCCC 
ATCCACATGC ACAGCCAGCT GGACCACCTG AGCCTTTATT ACTGCAGGTG TGCGCTCCCC 
GAGAATCCCA ACAACCACAC CTTACAGTAC TGGAAGGAGC ACAGCATCCC GACTGCAGAC 
GTGAACTGGG CAAACCTGAC TGTCAGCGAA TGCCAGGAGA TGCACGGGGA GTTCATAGGA 
TCGGCCTGTG GTCACCATGG GCCCTACACG CCTGACGTGC TCTTCTGGTC CTGTATTCTG 
TTCTTCGCTA CCTTCATCGT CTCAAGCACC TTGAAGACGT TTAAGACGAG CCGCTACTTC 
CCAACGAGGG TTCGCTCCAC GGTGAGTGAC TTCGCTGTGT TCCTCACCAT CTTTACTATG 
GTGATCCTAG ACTTTCTGAT TGGCGTCCCC TCGCCCAAGC TTCAGGTCCC CAGCGTGTTC 
AAGCCAACGA GGGATGATCG AGGATGGTTC ATTAGTCCCA TCGGCCCCAA TCCCTGGTGG 
ACCGTGATAG CCGCGATTAT CCCAGCTCTC CTGTGCACCA TCTTGATATT CATGGACCAG 
CAGATCACCG CCGTCATCAT TAACCGGAAG GAGCACAAGC TCAAGAAAGG CTGTGGCTAC 
CATCTGGACC TGCTCGTGGT GGCCATCATG CTGGGGGTCT GCTCCCTCAT GGGCCTGCCT 
TGGTTCGTGG CTGCGACCGT GCTGTCCATT ACTCATGTGA ATAGCCTCAA GCTGGAATCT 
GAATGCTCTG CTCCGGGGGA GCAGCCTAAG TTTCTGGGCA TCCGAGAACA GAGAGTCACG 
GGCCTCATGA TCTTTGTGCT GATGGGCTGC TCCGTCTTCA TGACAGCGGT CTTAAAGTTT 
ATCCCAATGC CAGTGCTCTA CGGAGTTTTC CTCTACATGG GAGTCTCTTC TCTACAAGGA 
ATCCAGTTCT TTGACCGTCT GAAGCTTTTT GGGATGCCTG CAAAACACCA GCCAGACTTC 
ATCTACCTGC GGCACGTGCC GCTGCGCAAA GTGCACCTCT TCACGCTGGT CCAGCTCACC 
TGCCTCGTCC TGCTCTGGGT CATTAAGGCG TCACCGGCTG CCATTGTTTT CCCAATGATG 
GTCCTGGCCT TGGTCTTCGT GAGGAAGGTC ATGGACCTCT GCTTCTCCAA GCGTGAGCTG 
AGCTGGCTGG ACGACCTCAT GCCTGAGAGC AAAAAGAAGA AGCTGGATGA TGCGAAGAAG 
AAGGAGGAGG AGGAGGAGGC TGAGAAGATG TTGGATATTG GGGGTGATAA GTTCCCCCTG 
GAAAGCAGGA AGTTGCTAAG TAGTCCTGGC AAGAACAACA GCTTCAGATG TGACCCTTCT 
GAGATTAATA TATCAGATGA AATGCCTAAA ACCACAGTCT GGAAGGCTCT CAGCATAAAT 
TCTGGAAACA CGAAAGAAAA AAGCCCCTTC AATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450387.1
CDS	62..2797
Translation	MRTSSIEEISDLILDQQELLRDLSDSVRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHSMDRDGQTVSPQSAPATNLEVKNGVNCEHSPVDLSKADLHFMKKIPAGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNICHVEPEPHGGHSGPELERTGRLFGGLVLDVKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCALPENPNNHTLQYWKEHSIPTADVNWANLTVSECQEMHGEFIGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSRYFPTRVRSTVSDFAVFLTIFTMVILDFLIGVPSPKLQVPSVFKPTRDDRGWFISPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAIMLGVCSLMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKEEEEEAEKMLDIGGDKFPLESRKLLSSPGKNNSFRCDPSEINISDEMPKTTVWKALSINSGNTKEKSPFN

Target ORF information:

RefSeq Version	XM_017594898.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594898.1

ORF Insert Sequence:

ATGCGCACAA GCAGCATAGA GGAGATCTCA GACCTGATCC TGGACCAGCA GGAGCTGCTC 
CGGGACCTGA GCGACAGCGT GCGGGTTAAG GTGCGGGAAG CCTTGCTGAA GAAGCATCAC 
CATCAGAACG AGAAGAAGAG GAACAACCTC ATCCCCATCG TCCGCTCCTT TGCCGAGGTC 
GGCAAGAAGC AGTCTGACCC GCATTCCATG GACAGAGATG GGCAAACCGT GTCTCCTCAG 
TCTGCTCCAG CTACCAACCT TGAAGTGAAG AATGGTGTGA ACTGTGAACA CAGCCCTGTG 
GATCTAAGCA AGGCGGACCT CCATTTCATG AAAAAGATTC CCGCAGGGGC AGAGGCCTCC 
AATGTCCTGG TTGGCGAGGT GGACACTCTG GACCGGCCCA TCGTCGCTTT CGTGAGGCTC 
TCCCCGGCCG TGCTCCTCTC TGGACTGACA GAAGTGCCCA TCCCAACGAG GTTTTTGTTT 
ATCTTACTGG GTCCGGTAGG AAAAGGGCAG CAGTACCATG AGATTGGCAG ATCCATGGCC 
ACCATCATGA CGGATGAGAT TTTTCACGAT GTGGCGTATA AAGCGAAAGA ACGGGATGAT 
CTCCTGGCTG GGATCGATGA GTTCCTGGAT CAAGTGACGG TGCTCCCACC AGGGGAGTGG 
GACCCGTCCA TTAGAATTGA GCCACCCAAG AATGTCCCTT CCCAGGAAAA AAGGAAGATG 
CCTGGCGTTC CAAACGGAAA CATTTGCCAC GTAGAACCTG AGCCACATGG GGGACACAGC 
GGGCCGGAAC TTGAGCGGAC GGGGCGGCTG TTTGGGGGCT TGGTGCTGGA TGTCAAACGG 
AAGGCTCCCT GGTACTGGAG TGACTACCGG GATGCTCTCA GCTTACAGTG TCTGGCCTCC 
TTCCTGTTCC TGTACTGTGC CTGCATGTCG CCTGTTATCA CCTTCGGGGG ACTGCTGGGA 
GAAGCCACGG AAGGACGCAT AAGTGCAATC GAATCGTTGT TTGGAGCCTC CATGACGGGG 
ATTGCCTACT CTCTGTTTGC TGGGCAGCCT CTCACCATCC TGGGAAGCAC GGGCCCTGTG 
CTGGTGTTTG AAAAGATTTT GTTCAAATTC TGCAAGGACT ACGCCCTTTC ATACCTCTCC 
TTGCGTGCTT GTATCGGGCT GTGGACCGCC TTCCTGTGTA TTGTCCTGGT GGCGACTGAT 
GCCAGTTCCC TCGTCTGCTA CATTACCCGC TTCACCGAGG AAGCCTTTGC CTCCCTGATT 
TGCATTATTT TCATCTATGA AGCCATAGAA AAGCTGATTC ACCTGGCCGA GACCTACCCC 
ATCCACATGC ACAGCCAGCT GGACCACCTG AGCCTTTATT ACTGCAGGTG TGCGCTCCCC 
GAGAATCCCA ACAACCACAC CTTACAGTAC TGGAAGGAGC ACAGCATCCC GACTGCAGAC 
GTGAACTGGG CAAACCTGAC TGTCAGCGAA TGCCAGGAGA TGCACGGGGA GTTCATAGGA 
TCGGCCTGTG GTCACCATGG GCCCTACACG CCTGACGTGC TCTTCTGGTC CTGTATTCTG 
TTCTTCGCTA CCTTCATCGT CTCAAGCACC TTGAAGACGT TTAAGACGAG CCGCTACTTC 
CCAACGAGGG TTCGCTCCAC GGTGAGTGAC TTCGCTGTGT TCCTCACCAT CTTTACTATG 
GTGATCCTAG ACTTTCTGAT TGGCGTCCCC TCGCCCAAGC TTCAGGTCCC CAGCGTGTTC 
AAGCCAACGA GGGATGATCG AGGATGGTTC ATTAGTCCCA TCGGCCCCAA TCCCTGGTGG 
ACCGTGATAG CCGCGATTAT CCCAGCTCTC CTGTGCACCA TCTTGATATT CATGGACCAG 
CAGATCACCG CCGTCATCAT TAACCGGAAG GAGCACAAGC TCAAGAAAGG CTGTGGCTAC 
CATCTGGACC TGCTCGTGGT GGCCATCATG CTGGGGGTCT GCTCCCTCAT GGGCCTGCCT 
TGGTTCGTGG CTGCGACCGT GCTGTCCATT ACTCATGTGA ATAGCCTCAA GCTGGAATCT 
GAATGCTCTG CTCCGGGGGA GCAGCCTAAG TTTCTGGGCA TCCGAGAACA GAGAGTCACG 
GGCCTCATGA TCTTTGTGCT GATGGGCTGC TCCGTCTTCA TGACAGCGGT CTTAAAGTTT 
ATCCCAATGC CAGTGCTCTA CGGAGTTTTC CTCTACATGG GAGTCTCTTC TCTACAAGGA 
ATCCAGTTCT TTGACCGTCT GAAGCTTTTT GGGATGCCTG CAAAACACCA GCCAGACTTC 
ATCTACCTGC GGCACGTGCC GCTGCGCAAA GTGCACCTCT TCACGCTGGT CCAGCTCACC 
TGCCTCGTCC TGCTCTGGGT CATTAAGGCG TCACCGGCTG CCATTGTTTT CCCAATGATG 
GTCCTGGCCT TGGTCTTCGT GAGGAAGGTC ATGGACCTCT GCTTCTCCAA GCGTGAGCTG 
AGCTGGCTGG ACGACCTCAT GCCTGAGAGC AAAAAGAAGA AGCTGGATGA TGCGAAGAAG 
AAGGAGGAGG AGGAGGAGGC TGAGAAGATG TTGGATATTG GGGGTGATAA GTTCCCCCTG 
GAAAGCAGGA AGTTGCTAAG TAGTCCTGGC AAGAACAACA GCTTCAGATG TGACCCTTCT 
GAGATTAATA TATCAGATGA AATGCCTAAA ACCACAGTCT GGAAGGCTCT CAGCATAAAT 
TCTGGAAACA CGAAAGAAAA AAGCCCCTTC AATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc4a8 ( XM_017594897.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_017450386.1 Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa62026
Clone ID Related Accession (Same CDS sequence)	XM_017594897.1
Accession Version	XM_017594897.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3279bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	electroneutral sodium bicarbonate exchanger 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005106.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGG CTGTTTGGGG GCTTGGTGCT GGATGTCAAA 
CGGAAGGCTC CCTGGTACTG GAGTGACTAC CGGGATGCTC TCAGCTTACA GTGTCTGGCC 
TCCTTCCTGT TCCTGTACTG TGCCTGCATG TCGCCTGTTA TCACCTTCGG GGGACTGCTG 
GGAGAAGCCA CGGAAGGACG CATAAGTGCA ATCGAATCGT TGTTTGGAGC CTCCATGACG 
GGGATTGCCT ACTCTCTGTT TGCTGGGCAG CCTCTCACCA TCCTGGGAAG CACGGGCCCT 
GTGCTGGTGT TTGAAAAGAT TTTGTTCAAA TTCTGCAAGG ACTACGCCCT TTCATACCTC 
TCCTTGCGTG CTTGTATCGG GCTGTGGACC GCCTTCCTGT GTATTGTCCT GGTGGCGACT 
GATGCCAGTT CCCTCGTCTG CTACATTACC CGCTTCACCG AGGAAGCCTT TGCCTCCCTG 
ATTTGCATTA TTTTCATCTA TGAAGCCATA GAAAAGCTGA TTCACCTGGC CGAGACCTAC 
CCCATCCACA TGCACAGCCA GCTGGACCAC CTGAGCCTTT ATTACTGCAG GTGTGCGCTC 
CCCGAGAATC CCAACAACCA CACCTTACAG TACTGGAAGG AGCACAGCAT CCCGACTGCA 
GACGTGAACT GGGCAAACCT GACTGTCAGC GAATGCCAGG AGATGCACGG GGAGTTCATA 
GGATCGGCCT GTGGTCACCA TGGGCCCTAC ACGCCTGACG TGCTCTTCTG GTCCTGTATT 
CTGTTCTTCG CTACCTTCAT CGTCTCAAGC ACCTTGAAGA CGTTTAAGAC GAGCCGCTAC 
TTCCCAACGA GGGTTCGCTC CACGGTGAGT GACTTCGCTG TGTTCCTCAC CATCTTTACT 
ATGGTGATCC TAGACTTTCT GATTGGCGTC CCCTCGCCCA AGCTTCAGGT CCCCAGCGTG 
TTCAAGCCAA CGAGGGATGA TCGAGGATGG TTCATTAGTC CCATCGGCCC CAATCCCTGG 
TGGACCGTGA TAGCCGCGAT TATCCCAGCT CTCCTGTGCA CCATCTTGAT ATTCATGGAC 
CAGCAGATCA CCGCCGTCAT CATTAACCGG AAGGAGCACA AGCTCAAGAA AGGCTGTGGC 
TACCATCTGG ACCTGCTCGT GGTGGCCATC ATGCTGGGGG TCTGCTCCCT CATGGGCCTG 
CCTTGGTTCG TGGCTGCGAC CGTGCTGTCC ATTACTCATG TGAATAGCCT CAAGCTGGAA 
TCTGAATGCT CTGCTCCGGG GGAGCAGCCT AAGTTTCTGG GCATCCGAGA ACAGAGAGTC 
ACGGGCCTCA TGATCTTTGT GCTGATGGGC TGCTCCGTCT TCATGACAGC GGTCTTAAAG 
TTTATCCCAA TGCCAGTGCT CTACGGAGTT TTCCTCTACA TGGGAGTCTC TTCTCTACAA 
GGAATCCAGT TCTTTGACCG TCTGAAGCTT TTTGGGATGC CTGCAAAACA CCAGCCAGAC 
TTCATCTACC TGCGGCACGT GCCGCTGCGC AAAGTGCACC TCTTCACGCT GGTCCAGCTC 
ACCTGCCTCG TCCTGCTCTG GGTCATTAAG GCGTCACCGG CTGCCATTGT TTTCCCAATG 
ATGGTCCTGG CCTTGGTCTT CGTGAGGAAG GTCATGGACC TCTGCTTCTC CAAGCGTGAG 
CTGAGCTGGC TGGACGACCT CATGCCTGAG AGCAAAAAGA AGAAGCTGGA TGATGCGAAG 
AAGAAGGAGG AGGAGGAGGA GGCTGAGAAG ATGTTGGATA TTGGGGGTGA TAAGTTCCCC 
CTGGAAAGCA GGAAGTTGCT AAGTAGTCCT GGCAAGAACA ACAGCTTCAG ATGTGACCCT 
TCTGAGATTA ATATATCAGA TGAAATGCCT AAAACCACAG TCTGGAAGGC TCTCAGCATA 
AATTCTGGAA ACACGAAAGA AAAAAGCCCC TTCAATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_017450386.1
CDS	180..3458
Translation	MPAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGGRGKGASQGEEGLEASAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEEAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGSVLLDMRASSIEEISDLILDQQELLRDLSDSVRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHSMDRDGQTVSPQSAPATNLEVKNGVNCEHSPVDLSKADLHFMKKIPAGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNICHVEPEPHGGHSGPELERTGRLFGGLVLDVKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCALPENPNNHTLQYWKEHSIPTADVNWANLTVSECQEMHGEFIGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSRYFPTRVRSTVSDFAVFLTIFTMVILDFLIGVPSPKLQVPSVFKPTRDDRGWFISPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAIMLGVCSLMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKEEEEEAEKMLDIGGDKFPLESRKLLSSPGKNNSFRCDPSEINISDEMPKTTVWKALSINSGNTKEKSPFN

Target ORF information:

RefSeq Version	XM_017594897.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017594897.1

ORF Insert Sequence:

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGG CTGTTTGGGG GCTTGGTGCT GGATGTCAAA 
CGGAAGGCTC CCTGGTACTG GAGTGACTAC CGGGATGCTC TCAGCTTACA GTGTCTGGCC 
TCCTTCCTGT TCCTGTACTG TGCCTGCATG TCGCCTGTTA TCACCTTCGG GGGACTGCTG 
GGAGAAGCCA CGGAAGGACG CATAAGTGCA ATCGAATCGT TGTTTGGAGC CTCCATGACG 
GGGATTGCCT ACTCTCTGTT TGCTGGGCAG CCTCTCACCA TCCTGGGAAG CACGGGCCCT 
GTGCTGGTGT TTGAAAAGAT TTTGTTCAAA TTCTGCAAGG ACTACGCCCT TTCATACCTC 
TCCTTGCGTG CTTGTATCGG GCTGTGGACC GCCTTCCTGT GTATTGTCCT GGTGGCGACT 
GATGCCAGTT CCCTCGTCTG CTACATTACC CGCTTCACCG AGGAAGCCTT TGCCTCCCTG 
ATTTGCATTA TTTTCATCTA TGAAGCCATA GAAAAGCTGA TTCACCTGGC CGAGACCTAC 
CCCATCCACA TGCACAGCCA GCTGGACCAC CTGAGCCTTT ATTACTGCAG GTGTGCGCTC 
CCCGAGAATC CCAACAACCA CACCTTACAG TACTGGAAGG AGCACAGCAT CCCGACTGCA 
GACGTGAACT GGGCAAACCT GACTGTCAGC GAATGCCAGG AGATGCACGG GGAGTTCATA 
GGATCGGCCT GTGGTCACCA TGGGCCCTAC ACGCCTGACG TGCTCTTCTG GTCCTGTATT 
CTGTTCTTCG CTACCTTCAT CGTCTCAAGC ACCTTGAAGA CGTTTAAGAC GAGCCGCTAC 
TTCCCAACGA GGGTTCGCTC CACGGTGAGT GACTTCGCTG TGTTCCTCAC CATCTTTACT 
ATGGTGATCC TAGACTTTCT GATTGGCGTC CCCTCGCCCA AGCTTCAGGT CCCCAGCGTG 
TTCAAGCCAA CGAGGGATGA TCGAGGATGG TTCATTAGTC CCATCGGCCC CAATCCCTGG 
TGGACCGTGA TAGCCGCGAT TATCCCAGCT CTCCTGTGCA CCATCTTGAT ATTCATGGAC 
CAGCAGATCA CCGCCGTCAT CATTAACCGG AAGGAGCACA AGCTCAAGAA AGGCTGTGGC 
TACCATCTGG ACCTGCTCGT GGTGGCCATC ATGCTGGGGG TCTGCTCCCT CATGGGCCTG 
CCTTGGTTCG TGGCTGCGAC CGTGCTGTCC ATTACTCATG TGAATAGCCT CAAGCTGGAA 
TCTGAATGCT CTGCTCCGGG GGAGCAGCCT AAGTTTCTGG GCATCCGAGA ACAGAGAGTC 
ACGGGCCTCA TGATCTTTGT GCTGATGGGC TGCTCCGTCT TCATGACAGC GGTCTTAAAG 
TTTATCCCAA TGCCAGTGCT CTACGGAGTT TTCCTCTACA TGGGAGTCTC TTCTCTACAA 
GGAATCCAGT TCTTTGACCG TCTGAAGCTT TTTGGGATGC CTGCAAAACA CCAGCCAGAC 
TTCATCTACC TGCGGCACGT GCCGCTGCGC AAAGTGCACC TCTTCACGCT GGTCCAGCTC 
ACCTGCCTCG TCCTGCTCTG GGTCATTAAG GCGTCACCGG CTGCCATTGT TTTCCCAATG 
ATGGTCCTGG CCTTGGTCTT CGTGAGGAAG GTCATGGACC TCTGCTTCTC CAAGCGTGAG 
CTGAGCTGGC TGGACGACCT CATGCCTGAG AGCAAAAAGA AGAAGCTGGA TGATGCGAAG 
AAGAAGGAGG AGGAGGAGGA GGCTGAGAAG ATGTTGGATA TTGGGGGTGA TAAGTTCCCC 
CTGGAAAGCA GGAAGTTGCT AAGTAGTCCT GGCAAGAACA ACAGCTTCAG ATGTGACCCT 
TCTGAGATTA ATATATCAGA TGAAATGCCT AAAACCACAG TCTGGAAGGC TCTCAGCATA 
AATTCTGGAA ACACGAAAGA AAAAAGCCCC TTCAATTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc4a8 ( NM_199497.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_955791.1 Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 1, mRNA.

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CloneID	ORa05379
Clone ID Related Accession (Same CDS sequence)	NM_199497.2
Accession Version	NM_199497.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3204bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-22
Organism	Rattus norvegicus(Norway rat)
Product	electroneutral sodium bicarbonate exchanger 1 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058908.1 and AABR07058912.1. On Aug 1, 2012 this sequence version replaced NM_199497.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AY489025.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGC TTACAGTGTC TGGCCTCCTT CCTGTTCCTG 
TACTGTGCCT GCATGTCGCC TGTTATCACC TTCGGGGGAC TGCTGGGAGA AGCCACGGAA 
GGACGCATAA GTGCAATCGA ATCGTTGTTT GGAGCCTCCA TGACGGGGAT TGCCTACTCT 
CTGTTTGCTG GGCAGCCTCT CACCATCCTG GGAAGCACGG GCCCTGTGCT GGTGTTTGAA 
AAGATTTTGT TCAAATTCTG CAAGGACTAC GCCCTTTCAT ACCTCTCCTT GCGTGCTTGT 
ATCGGGCTGT GGACCGCCTT CCTGTGTATT GTCCTGGTGG CGACTGATGC CAGTTCCCTC 
GTCTGCTACA TTACCCGCTT CACCGAGGAA GCCTTTGCCT CCCTGATTTG CATTATTTTC 
ATCTATGAAG CCATAGAAAA GCTGATTCAC CTGGCCGAGA CCTACCCCAT CCACATGCAC 
AGCCAGCTGG ACCACCTGAG CCTTTATTAC TGCAGGTGTG CGCTCCCCGA GAATCCCAAC 
AACCACACCT TACAGTACTG GAAGGAGCAC AGCATCCCGA CTGCAGACGT GAACTGGGCA 
AACCTGACTG TCAGCGAATG CCAGGAGATG CACGGGGAGT TCATAGGATC GGCCTGTGGT 
CACCATGGGC CCTACACGCC TGACGTGCTC TTCTGGTCCT GTATTCTGTT CTTCGCTACC 
TTCATCGTCT CAAGCACCTT GAAGACGTTT AAGACGAGCC GCTACTTCCC AACGAGGGTT 
CGCTCCACGG TGAGTGACTT CGCTGTGTTC CTCACCATCT TTACTATGGT GATCCTAGAC 
TTTCTGATTG GCGTCCCCTC GCCCAAGCTT CAGGTCCCCA GCGTGTTCAA GCCAACGAGG 
GATGATCGAG GATGGTTCAT TAGTCCCATC GGCCCCAATC CCTGGTGGAC CGTGATAGCC 
GCGATTATCC CAGCTCTCCT GTGCACCATC TTGATATTCA TGGACCAGCA GATCACCGCC 
GTCATCATTA ACCGGAAGGA GCACAAGCTC AAGAAAGGCT GTGGCTACCA TCTGGACCTG 
CTCGTGGTGG CCATCATGCT GGGGGTCTGC TCCCTCATGG GCCTGCCTTG GTTCGTGGCT 
GCGACCGTGC TGTCCATTAC TCATGTGAAT AGCCTCAAGC TGGAATCTGA ATGCTCTGCT 
CCGGGGGAGC AGCCTAAGTT TCTGGGCATC CGAGAACAGA GAGTCACGGG CCTCATGATC 
TTTGTGCTGA TGGGCTGCTC CGTCTTCATG ACAGCGGTCT TAAAGTTTAT CCCAATGCCA 
GTGCTCTACG GAGTTTTCCT CTACATGGGA GTCTCTTCTC TACAAGGAAT CCAGTTCTTT 
GACCGTCTGA AGCTTTTTGG GATGCCTGCA AAACACCAGC CAGACTTCAT CTACCTGCGG 
CACGTGCCGC TGCGCAAAGT GCACCTCTTC ACGCTGGTCC AGCTCACCTG CCTCGTCCTG 
CTCTGGGTCA TTAAGGCGTC ACCGGCTGCC ATTGTTTTCC CAATGATGGT CCTGGCCTTG 
GTCTTCGTGA GGAAGGTCAT GGACCTCTGC TTCTCCAAGC GTGAGCTGAG CTGGCTGGAC 
GACCTCATGC CTGAGAGCAA AAAGAAGAAG CTGGATGATG CGAAGAAGAA GGAGGAGGAG 
GAGGAGGCTG AGAAGATGTT GGATATTGGG GGTGATAAGT TCCCCCTGGA AAGCAGGAAG 
TTGCTAAGTA GTCCTGGCAA GAACAACAGC TTCAGATGTG ACCCTTCTGA GATTAATATA 
TCAGATGAAA TGCCTAAAAC CACAGTCTGG AAGGCTCTCA GCATAAATTC TGGAAACACG 
AAAGAAAAAA GCCCCTTCAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_955791.1
CDS	119..3322
Translation	MPAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGGRGKGASQGEEGLEASAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEEAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGSVLLDMRASSIEEISDLILDQQELLRDLSDSVRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHSMDRDGQTVSPQSAPATNLEVKNGVNCEHSPVDLSKADLHFMKKIPAGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNICHVEPEPHGGHSGPELERTGRLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCALPENPNNHTLQYWKEHSIPTADVNWANLTVSECQEMHGEFIGSACGHHGPYTPDVLFWSCILFFATFIVSSTLKTFKTSRYFPTRVRSTVSDFAVFLTIFTMVILDFLIGVPSPKLQVPSVFKPTRDDRGWFISPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAIMLGVCSLMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKEEEEEAEKMLDIGGDKFPLESRKLLSSPGKNNSFRCDPSEINISDEMPKTTVWKALSINSGNTKEKSPFN

Target ORF information:

RefSeq Version	NM_199497.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_199497.2

ORF Insert Sequence:

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGC TTACAGTGTC TGGCCTCCTT CCTGTTCCTG 
TACTGTGCCT GCATGTCGCC TGTTATCACC TTCGGGGGAC TGCTGGGAGA AGCCACGGAA 
GGACGCATAA GTGCAATCGA ATCGTTGTTT GGAGCCTCCA TGACGGGGAT TGCCTACTCT 
CTGTTTGCTG GGCAGCCTCT CACCATCCTG GGAAGCACGG GCCCTGTGCT GGTGTTTGAA 
AAGATTTTGT TCAAATTCTG CAAGGACTAC GCCCTTTCAT ACCTCTCCTT GCGTGCTTGT 
ATCGGGCTGT GGACCGCCTT CCTGTGTATT GTCCTGGTGG CGACTGATGC CAGTTCCCTC 
GTCTGCTACA TTACCCGCTT CACCGAGGAA GCCTTTGCCT CCCTGATTTG CATTATTTTC 
ATCTATGAAG CCATAGAAAA GCTGATTCAC CTGGCCGAGA CCTACCCCAT CCACATGCAC 
AGCCAGCTGG ACCACCTGAG CCTTTATTAC TGCAGGTGTG CGCTCCCCGA GAATCCCAAC 
AACCACACCT TACAGTACTG GAAGGAGCAC AGCATCCCGA CTGCAGACGT GAACTGGGCA 
AACCTGACTG TCAGCGAATG CCAGGAGATG CACGGGGAGT TCATAGGATC GGCCTGTGGT 
CACCATGGGC CCTACACGCC TGACGTGCTC TTCTGGTCCT GTATTCTGTT CTTCGCTACC 
TTCATCGTCT CAAGCACCTT GAAGACGTTT AAGACGAGCC GCTACTTCCC AACGAGGGTT 
CGCTCCACGG TGAGTGACTT CGCTGTGTTC CTCACCATCT TTACTATGGT GATCCTAGAC 
TTTCTGATTG GCGTCCCCTC GCCCAAGCTT CAGGTCCCCA GCGTGTTCAA GCCAACGAGG 
GATGATCGAG GATGGTTCAT TAGTCCCATC GGCCCCAATC CCTGGTGGAC CGTGATAGCC 
GCGATTATCC CAGCTCTCCT GTGCACCATC TTGATATTCA TGGACCAGCA GATCACCGCC 
GTCATCATTA ACCGGAAGGA GCACAAGCTC AAGAAAGGCT GTGGCTACCA TCTGGACCTG 
CTCGTGGTGG CCATCATGCT GGGGGTCTGC TCCCTCATGG GCCTGCCTTG GTTCGTGGCT 
GCGACCGTGC TGTCCATTAC TCATGTGAAT AGCCTCAAGC TGGAATCTGA ATGCTCTGCT 
CCGGGGGAGC AGCCTAAGTT TCTGGGCATC CGAGAACAGA GAGTCACGGG CCTCATGATC 
TTTGTGCTGA TGGGCTGCTC CGTCTTCATG ACAGCGGTCT TAAAGTTTAT CCCAATGCCA 
GTGCTCTACG GAGTTTTCCT CTACATGGGA GTCTCTTCTC TACAAGGAAT CCAGTTCTTT 
GACCGTCTGA AGCTTTTTGG GATGCCTGCA AAACACCAGC CAGACTTCAT CTACCTGCGG 
CACGTGCCGC TGCGCAAAGT GCACCTCTTC ACGCTGGTCC AGCTCACCTG CCTCGTCCTG 
CTCTGGGTCA TTAAGGCGTC ACCGGCTGCC ATTGTTTTCC CAATGATGGT CCTGGCCTTG 
GTCTTCGTGA GGAAGGTCAT GGACCTCTGC TTCTCCAAGC GTGAGCTGAG CTGGCTGGAC 
GACCTCATGC CTGAGAGCAA AAAGAAGAAG CTGGATGATG CGAAGAAGAA GGAGGAGGAG 
GAGGAGGCTG AGAAGATGTT GGATATTGGG GGTGATAAGT TCCCCCTGGA AAGCAGGAAG 
TTGCTAAGTA GTCCTGGCAA GAACAACAGC TTCAGATGTG ACCCTTCTGA GATTAATATA 
TCAGATGAAA TGCCTAAAAC CACAGTCTGG AAGGCTCTCA GCATAAATTC TGGAAACACG 
AAAGAAAAAA GCCCCTTCAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc4a8 ( NM_001270794.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257723.1 Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 2, mRNA.

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CloneID	ORa09808
Clone ID Related Accession (Same CDS sequence)	NM_001270794.1
Accession Version	NM_001270794.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3114bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-22
Organism	Rattus norvegicus(Norway rat)
Product	electroneutral sodium bicarbonate exchanger 1 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058908.1 and AABR07058912.1. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) contains an alternate segment and lacks another alternate segment compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AY489024.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGG CTGTTTGGGG GCTTGGTGCT GGATGTCAAA 
CGGAAGGCTC CCTGGTACTG GAGTGACTAC CGGGATGCTC TCAGCTTACA GTGTCTGGCC 
TCCTTCCTGT TCCTGTACTG TGCCTGCATG TCGCCTGTTA TCACCTTCGG GGGACTGCTG 
GGAGAAGCCA CGGAAGGACG CATAAGTGCA ATCGAATCGT TGTTTGGAGC CTCCATGACG 
GGGATTGCCT ACTCTCTGTT TGCTGGGCAG CCTCTCACCA TCCTGGGAAG CACGGGCCCT 
GTGCTGGTGT TTGAAAAGAT TTTGTTCAAA TTCTGCAAGG ACTACGCCCT TTCATACCTC 
TCCTTGCGTG CTTGTATCGG GCTGTGGACC GCCTTCCTGT GTATTGTCCT GGTGGCGACT 
GATGCCAGTT CCCTCGTCTG CTACATTACC CGCTTCACCG AGGAAGCCTT TGCCTCCCTG 
ATTTGCATTA TTTTCATCTA TGAAGCCATA GAAAAGCTGA TTCACCTGGC CGAGACCTAC 
CCCATCCACA TGCACAGCCA GCTGGACCAC CTGAGCCTTT ATTACTGCAG GTGTGCGCTC 
CCCGAGAATC CCAACAACCA CACCTTACAG TACTGGAAGG AGCACAGCAT CCCGACTGCA 
GACGTGAACT GGGCAAACCT GACTGTCAGC GTTCGCTCCA CGGTGAGTGA CTTCGCTGTG 
TTCCTCACCA TCTTTACTAT GGTGATCCTA GACTTTCTGA TTGGCGTCCC CTCGCCCAAG 
CTTCAGGTCC CCAGCGTGTT CAAGCCAACG AGGGATGATC GAGGATGGTT CATTAGTCCC 
ATCGGCCCCA ATCCCTGGTG GACCGTGATA GCCGCGATTA TCCCAGCTCT CCTGTGCACC 
ATCTTGATAT TCATGGACCA GCAGATCACC GCCGTCATCA TTAACCGGAA GGAGCACAAG 
CTCAAGAAAG GCTGTGGCTA CCATCTGGAC CTGCTCGTGG TGGCCATCAT GCTGGGGGTC 
TGCTCCCTCA TGGGCCTGCC TTGGTTCGTG GCTGCGACCG TGCTGTCCAT TACTCATGTG 
AATAGCCTCA AGCTGGAATC TGAATGCTCT GCTCCGGGGG AGCAGCCTAA GTTTCTGGGC 
ATCCGAGAAC AGAGAGTCAC GGGCCTCATG ATCTTTGTGC TGATGGGCTG CTCCGTCTTC 
ATGACAGCGG TCTTAAAGTT TATCCCAATG CCAGTGCTCT ACGGAGTTTT CCTCTACATG 
GGAGTCTCTT CTCTACAAGG AATCCAGTTC TTTGACCGTC TGAAGCTTTT TGGGATGCCT 
GCAAAACACC AGCCAGACTT CATCTACCTG CGGCACGTGC CGCTGCGCAA AGTGCACCTC 
TTCACGCTGG TCCAGCTCAC CTGCCTCGTC CTGCTCTGGG TCATTAAGGC GTCACCGGCT 
GCCATTGTTT TCCCAATGAT GGTCCTGGCC TTGGTCTTCG TGAGGAAGGT CATGGACCTC 
TGCTTCTCCA AGCGTGAGCT GAGCTGGCTG GACGACCTCA TGCCTGAGAG CAAAAAGAAG 
AAGCTGGATG ATGCGAAGAA GAAGGAGGAG GAGGAGGCTG AGAAGATGTT GGATATTGGG 
GGTGATAAGT TCCCCCTGGA AAGCAGGAAG TTGCTAAGTA GTCCTGGCAA GAACAACAGC 
TTCAGATGTG ACCCTTCTGA GATTAATATA TCAGATGAAA TGCCTAAAAC CACAGTCTGG 
AAGGCTCTCA GCATAAATTC TGGAAACACG AAAGAAAAAA GCCCCTTCAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257723.1
CDS	119..3232
Translation	MPAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGGRGKGASQGEEGLEASAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEEAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGSVLLDMRASSIEEISDLILDQQELLRDLSDSVRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHSMDRDGQTVSPQSAPATNLEVKNGVNCEHSPVDLSKADLHFMKKIPAGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNICHVEPEPHGGHSGPELERTGRLFGGLVLDVKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCALPENPNNHTLQYWKEHSIPTADVNWANLTVSVRSTVSDFAVFLTIFTMVILDFLIGVPSPKLQVPSVFKPTRDDRGWFISPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAIMLGVCSLMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKEEEEAEKMLDIGGDKFPLESRKLLSSPGKNNSFRCDPSEINISDEMPKTTVWKALSINSGNTKEKSPFN

Target ORF information:

RefSeq Version	NM_001270794.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270794.1

ORF Insert Sequence:

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGG CTGTTTGGGG GCTTGGTGCT GGATGTCAAA 
CGGAAGGCTC CCTGGTACTG GAGTGACTAC CGGGATGCTC TCAGCTTACA GTGTCTGGCC 
TCCTTCCTGT TCCTGTACTG TGCCTGCATG TCGCCTGTTA TCACCTTCGG GGGACTGCTG 
GGAGAAGCCA CGGAAGGACG CATAAGTGCA ATCGAATCGT TGTTTGGAGC CTCCATGACG 
GGGATTGCCT ACTCTCTGTT TGCTGGGCAG CCTCTCACCA TCCTGGGAAG CACGGGCCCT 
GTGCTGGTGT TTGAAAAGAT TTTGTTCAAA TTCTGCAAGG ACTACGCCCT TTCATACCTC 
TCCTTGCGTG CTTGTATCGG GCTGTGGACC GCCTTCCTGT GTATTGTCCT GGTGGCGACT 
GATGCCAGTT CCCTCGTCTG CTACATTACC CGCTTCACCG AGGAAGCCTT TGCCTCCCTG 
ATTTGCATTA TTTTCATCTA TGAAGCCATA GAAAAGCTGA TTCACCTGGC CGAGACCTAC 
CCCATCCACA TGCACAGCCA GCTGGACCAC CTGAGCCTTT ATTACTGCAG GTGTGCGCTC 
CCCGAGAATC CCAACAACCA CACCTTACAG TACTGGAAGG AGCACAGCAT CCCGACTGCA 
GACGTGAACT GGGCAAACCT GACTGTCAGC GTTCGCTCCA CGGTGAGTGA CTTCGCTGTG 
TTCCTCACCA TCTTTACTAT GGTGATCCTA GACTTTCTGA TTGGCGTCCC CTCGCCCAAG 
CTTCAGGTCC CCAGCGTGTT CAAGCCAACG AGGGATGATC GAGGATGGTT CATTAGTCCC 
ATCGGCCCCA ATCCCTGGTG GACCGTGATA GCCGCGATTA TCCCAGCTCT CCTGTGCACC 
ATCTTGATAT TCATGGACCA GCAGATCACC GCCGTCATCA TTAACCGGAA GGAGCACAAG 
CTCAAGAAAG GCTGTGGCTA CCATCTGGAC CTGCTCGTGG TGGCCATCAT GCTGGGGGTC 
TGCTCCCTCA TGGGCCTGCC TTGGTTCGTG GCTGCGACCG TGCTGTCCAT TACTCATGTG 
AATAGCCTCA AGCTGGAATC TGAATGCTCT GCTCCGGGGG AGCAGCCTAA GTTTCTGGGC 
ATCCGAGAAC AGAGAGTCAC GGGCCTCATG ATCTTTGTGC TGATGGGCTG CTCCGTCTTC 
ATGACAGCGG TCTTAAAGTT TATCCCAATG CCAGTGCTCT ACGGAGTTTT CCTCTACATG 
GGAGTCTCTT CTCTACAAGG AATCCAGTTC TTTGACCGTC TGAAGCTTTT TGGGATGCCT 
GCAAAACACC AGCCAGACTT CATCTACCTG CGGCACGTGC CGCTGCGCAA AGTGCACCTC 
TTCACGCTGG TCCAGCTCAC CTGCCTCGTC CTGCTCTGGG TCATTAAGGC GTCACCGGCT 
GCCATTGTTT TCCCAATGAT GGTCCTGGCC TTGGTCTTCG TGAGGAAGGT CATGGACCTC 
TGCTTCTCCA AGCGTGAGCT GAGCTGGCTG GACGACCTCA TGCCTGAGAG CAAAAAGAAG 
AAGCTGGATG ATGCGAAGAA GAAGGAGGAG GAGGAGGCTG AGAAGATGTT GGATATTGGG 
GGTGATAAGT TCCCCCTGGA AAGCAGGAAG TTGCTAAGTA GTCCTGGCAA GAACAACAGC 
TTCAGATGTG ACCCTTCTGA GATTAATATA TCAGATGAAA TGCCTAAAAC CACAGTCTGG 
AAGGCTCTCA GCATAAATTC TGGAAACACG AAAGAAAAAA GCCCCTTCAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Slc4a8 ( NM_001270795.1 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_001257724.1 Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 3, mRNA.

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CloneID	ORa09813
Clone ID Related Accession (Same CDS sequence)	NM_001270795.1
Accession Version	NM_001270795.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3042bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-22
Organism	Rattus norvegicus(Norway rat)
Product	electroneutral sodium bicarbonate exchanger 1 isoform 3
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07058908.1 and AABR07058912.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) lacks an alternate internal segment compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AY489026.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END##

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGC TTACAGTGTC TGGCCTCCTT CCTGTTCCTG 
TACTGTGCCT GCATGTCGCC TGTTATCACC TTCGGGGGAC TGCTGGGAGA AGCCACGGAA 
GGACGCATAA GTGCAATCGA ATCGTTGTTT GGAGCCTCCA TGACGGGGAT TGCCTACTCT 
CTGTTTGCTG GGCAGCCTCT CACCATCCTG GGAAGCACGG GCCCTGTGCT GGTGTTTGAA 
AAGATTTTGT TCAAATTCTG CAAGGACTAC GCCCTTTCAT ACCTCTCCTT GCGTGCTTGT 
ATCGGGCTGT GGACCGCCTT CCTGTGTATT GTCCTGGTGG CGACTGATGC CAGTTCCCTC 
GTCTGCTACA TTACCCGCTT CACCGAGGAA GCCTTTGCCT CCCTGATTTG CATTATTTTC 
ATCTATGAAG CCATAGAAAA GCTGATTCAC CTGGCCGAGA CCTACCCCAT CCACATGCAC 
AGCCAGCTGG ACCACCTGAG CCTTTATTAC TGCAGGTGTG CGCTCCCCGA GAATCCCAAC 
AACCACACCT TACAGTACTG GAAGGAGCAC AGCATCCCGA CTGCAGACGT GAACTGGGCA 
AACCTGACTG TCAGCGTTCG CTCCACGGTG AGTGACTTCG CTGTGTTCCT CACCATCTTT 
ACTATGGTGA TCCTAGACTT TCTGATTGGC GTCCCCTCGC CCAAGCTTCA GGTCCCCAGC 
GTGTTCAAGC CAACGAGGGA TGATCGAGGA TGGTTCATTA GTCCCATCGG CCCCAATCCC 
TGGTGGACCG TGATAGCCGC GATTATCCCA GCTCTCCTGT GCACCATCTT GATATTCATG 
GACCAGCAGA TCACCGCCGT CATCATTAAC CGGAAGGAGC ACAAGCTCAA GAAAGGCTGT 
GGCTACCATC TGGACCTGCT CGTGGTGGCC ATCATGCTGG GGGTCTGCTC CCTCATGGGC 
CTGCCTTGGT TCGTGGCTGC GACCGTGCTG TCCATTACTC ATGTGAATAG CCTCAAGCTG 
GAATCTGAAT GCTCTGCTCC GGGGGAGCAG CCTAAGTTTC TGGGCATCCG AGAACAGAGA 
GTCACGGGCC TCATGATCTT TGTGCTGATG GGCTGCTCCG TCTTCATGAC AGCGGTCTTA 
AAGTTTATCC CAATGCCAGT GCTCTACGGA GTTTTCCTCT ACATGGGAGT CTCTTCTCTA 
CAAGGAATCC AGTTCTTTGA CCGTCTGAAG CTTTTTGGGA TGCCTGCAAA ACACCAGCCA 
GACTTCATCT ACCTGCGGCA CGTGCCGCTG CGCAAAGTGC ACCTCTTCAC GCTGGTCCAG 
CTCACCTGCC TCGTCCTGCT CTGGGTCATT AAGGCGTCAC CGGCTGCCAT TGTTTTCCCA 
ATGATGGTCC TGGCCTTGGT CTTCGTGAGG AAGGTCATGG ACCTCTGCTT CTCCAAGCGT 
GAGCTGAGCT GGCTGGACGA CCTCATGCCT GAGAGCAAAA AGAAGAAGCT GGATGATGCG 
AAGAAGAAGG AGGAGGAGGA GGAGGCTGAG AAGATGTTGG ATATTGGGGG TGATAAGTTC 
CCCCTGGAAA GCAGGAAGTT GCTAAGTAGT CCTGGCAAGA ACAACAGCTT CAGATGTGAC 
CCTTCTGAGA TTAATATATC AGATGAAATG CCTAAAACCA CAGTCTGGAA GGCTCTCAGC 
ATAAATTCTG GAAACACGAA AGAAAAAAGC CCCTTCAATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257724.1
CDS	119..3160
Translation	MPAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGGRGKGASQGEEGLEASAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEEAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGSVLLDMRASSIEEISDLILDQQELLRDLSDSVRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHSMDRDGQTVSPQSAPATNLEVKNGVNCEHSPVDLSKADLHFMKKIPAGAEASNVLVGEVDTLDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNICHVEPEPHGGHSGPELERTGRLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCALPENPNNHTLQYWKEHSIPTADVNWANLTVSVRSTVSDFAVFLTIFTMVILDFLIGVPSPKLQVPSVFKPTRDDRGWFISPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLVVAIMLGVCSLMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAVLKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLVQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKEEEEEAEKMLDIGGDKFPLESRKLLSSPGKNNSFRCDPSEINISDEMPKTTVWKALSINSGNTKEKSPFN

Target ORF information:

RefSeq Version	NM_001270795.1
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus solute carrier family 4 member 8 (Slc4a8), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270795.1

ORF Insert Sequence:

ATGCCCGCCG GGAGCAACGA GCCGGACGGC GTCCTCAGCT ATCAGAGACC AGATGAGGAA 
GCTGTGGTGG ATCAGGGTGG GACCAGCACG ATTCTCAACA TTCACTATGA GAAAGAAGAG 
TTGGAAGGTC ATAGAACTCT GTATGTGGGG GTTCGGATGC CACTGGGGAG GCAGAGCCAT 
CGTCACCACC GAACTCATGG CCAGAAGCAC CGGAGACGAG GAGGGCGGGG CAAAGGAGCC 
AGCCAGGGCG AGGAGGGCTT GGAAGCCTCC GCCCACGACA CCCCGTCTCA GCGCGTACAG 
TTCATTCTTG GCACTGAGGA AGATGAGGAG CACGTTCCTC ATGAGCTGTT CACAGAGCTG 
GACGAGATCT GTATGAAAGA GGGGGAAGAA GCCGAATGGA AGGAAACGGC CAGGTGGCTG 
AAGTTTGAAG AGGACGTGGA GGACGGGGGA GAGCGCTGGA GCAAGCCTTA CGTGGCCACA 
CTTTCTCTGC ACAGCCTGTT TGAGCTGAGG AGCTGCCTCA TCAATGGCTC CGTCCTCCTG 
GACATGCGCG CAAGCAGCAT AGAGGAGATC TCAGACCTGA TCCTGGACCA GCAGGAGCTG 
CTCCGGGACC TGAGCGACAG CGTGCGGGTT AAGGTGCGGG AAGCCTTGCT GAAGAAGCAT 
CACCATCAGA ACGAGAAGAA GAGGAACAAC CTCATCCCCA TCGTCCGCTC CTTTGCCGAG 
GTCGGCAAGA AGCAGTCTGA CCCGCATTCC ATGGACAGAG ATGGGCAAAC CGTGTCTCCT 
CAGTCTGCTC CAGCTACCAA CCTTGAAGTG AAGAATGGTG TGAACTGTGA ACACAGCCCT 
GTGGATCTAA GCAAGGCGGA CCTCCATTTC ATGAAAAAGA TTCCCGCAGG GGCAGAGGCC 
TCCAATGTCC TGGTTGGCGA GGTGGACACT CTGGACCGGC CCATCGTCGC TTTCGTGAGG 
CTCTCCCCGG CCGTGCTCCT CTCTGGACTG ACAGAAGTGC CCATCCCAAC GAGGTTTTTG 
TTTATCTTAC TGGGTCCGGT AGGAAAAGGG CAGCAGTACC ATGAGATTGG CAGATCCATG 
GCCACCATCA TGACGGATGA GATTTTTCAC GATGTGGCGT ATAAAGCGAA AGAACGGGAT 
GATCTCCTGG CTGGGATCGA TGAGTTCCTG GATCAAGTGA CGGTGCTCCC ACCAGGGGAG 
TGGGACCCGT CCATTAGAAT TGAGCCACCC AAGAATGTCC CTTCCCAGGA AAAAAGGAAG 
ATGCCTGGCG TTCCAAACGG AAACATTTGC CACGTAGAAC CTGAGCCACA TGGGGGACAC 
AGCGGGCCGG AACTTGAGCG GACGGGGCGC TTACAGTGTC TGGCCTCCTT CCTGTTCCTG 
TACTGTGCCT GCATGTCGCC TGTTATCACC TTCGGGGGAC TGCTGGGAGA AGCCACGGAA 
GGACGCATAA GTGCAATCGA ATCGTTGTTT GGAGCCTCCA TGACGGGGAT TGCCTACTCT 
CTGTTTGCTG GGCAGCCTCT CACCATCCTG GGAAGCACGG GCCCTGTGCT GGTGTTTGAA 
AAGATTTTGT TCAAATTCTG CAAGGACTAC GCCCTTTCAT ACCTCTCCTT GCGTGCTTGT 
ATCGGGCTGT GGACCGCCTT CCTGTGTATT GTCCTGGTGG CGACTGATGC CAGTTCCCTC 
GTCTGCTACA TTACCCGCTT CACCGAGGAA GCCTTTGCCT CCCTGATTTG CATTATTTTC 
ATCTATGAAG CCATAGAAAA GCTGATTCAC CTGGCCGAGA CCTACCCCAT CCACATGCAC 
AGCCAGCTGG ACCACCTGAG CCTTTATTAC TGCAGGTGTG CGCTCCCCGA GAATCCCAAC 
AACCACACCT TACAGTACTG GAAGGAGCAC AGCATCCCGA CTGCAGACGT GAACTGGGCA 
AACCTGACTG TCAGCGTTCG CTCCACGGTG AGTGACTTCG CTGTGTTCCT CACCATCTTT 
ACTATGGTGA TCCTAGACTT TCTGATTGGC GTCCCCTCGC CCAAGCTTCA GGTCCCCAGC 
GTGTTCAAGC CAACGAGGGA TGATCGAGGA TGGTTCATTA GTCCCATCGG CCCCAATCCC 
TGGTGGACCG TGATAGCCGC GATTATCCCA GCTCTCCTGT GCACCATCTT GATATTCATG 
GACCAGCAGA TCACCGCCGT CATCATTAAC CGGAAGGAGC ACAAGCTCAA GAAAGGCTGT 
GGCTACCATC TGGACCTGCT CGTGGTGGCC ATCATGCTGG GGGTCTGCTC CCTCATGGGC 
CTGCCTTGGT TCGTGGCTGC GACCGTGCTG TCCATTACTC ATGTGAATAG CCTCAAGCTG 
GAATCTGAAT GCTCTGCTCC GGGGGAGCAG CCTAAGTTTC TGGGCATCCG AGAACAGAGA 
GTCACGGGCC TCATGATCTT TGTGCTGATG GGCTGCTCCG TCTTCATGAC AGCGGTCTTA 
AAGTTTATCC CAATGCCAGT GCTCTACGGA GTTTTCCTCT ACATGGGAGT CTCTTCTCTA 
CAAGGAATCC AGTTCTTTGA CCGTCTGAAG CTTTTTGGGA TGCCTGCAAA ACACCAGCCA 
GACTTCATCT ACCTGCGGCA CGTGCCGCTG CGCAAAGTGC ACCTCTTCAC GCTGGTCCAG 
CTCACCTGCC TCGTCCTGCT CTGGGTCATT AAGGCGTCAC CGGCTGCCAT TGTTTTCCCA 
ATGATGGTCC TGGCCTTGGT CTTCGTGAGG AAGGTCATGG ACCTCTGCTT CTCCAAGCGT 
GAGCTGAGCT GGCTGGACGA CCTCATGCCT GAGAGCAAAA AGAAGAAGCT GGATGATGCG 
AAGAAGAAGG AGGAGGAGGA GGAGGCTGAG AAGATGTTGG ATATTGGGGG TGATAAGTTC 
CCCCTGGAAA GCAGGAAGTT GCTAAGTAGT CCTGGCAAGA ACAACAGCTT CAGATGTGAC 
CCTTCTGAGA TTAATATATC AGATGAAATG CCTAAAACCA CAGTCTGGAA GGCTCTCAGC 
ATAAATTCTG GAAACACGAA AGAAAAAAGC CCCTTCAATT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Effect of prediabetes on membrane bicarbonate transporters in testis and epididymis.
The Journal of membrane biology246(12)877-83(2013 Dec)
Bernardino RL,Martins AD,Socorro S,Alves MG,Oliveira PF

Immunocytochemical identification of electroneutral Na?-coupled HCO?? transporters in freshly dissociated mouse medullary raph? neurons.
Neuroscience246451-67(2013 Aug)
Coley AA,Ruffin VA,Moss FJ,Hopfer U,Boron WF

The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals.
The Journal of comparative neurology520(7)1481-92(2012 May)
Burette AC,Weinberg RJ,Sassani P,Abuladze N,Kao L,Kurtz I

The sodium-driven chloride/bicarbonate exchanger NDCBE in rat brain is upregulated by chronic metabolic acidosis.
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Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNS.
Neuroscience153(1)162-74(2008 Apr)
Chen LM,Kelly ML,Parker MD,Bouyer P,Gill HS,Felie JM,Davis BA,Boron WF

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Slc4a8 cDNA ORF clone, Rattus norvegicus(Norway rat)

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