Gene Symbol | Tnfsf12 |
Entrez Gene ID | 360548 |
Full Name | TNF superfamily member 12 |
Synonyms | TWEAK,Tnlg4a |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Tnfsf12 cDNA ORF clone
Gene Symbol | Tnfsf12 |
Entrez Gene ID | 360548 |
Full Name | TNF superfamily member 12 |
Synonyms | TWEAK,Tnlg4a |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001001513.2 | NP_001001513.2 | tumor necrosis factor ligand superfamily member 12 |
XM_006246745.3 | XP_006246807.1 | tumor necrosis factor ligand superfamily member 12 isoform X1 |
Pan troglodytes (chimpanzee) | TNFSF12 | NP_001192058.1 |
Rattus norvegicus (Norway rat) | Tnfsf12 | NP_001001513.2 |
Danio rerio (zebrafish) | tnfsf12 | NP_001070075.1 |
Canis lupus familiaris (dog) | TNFSF12 | NP_001192097.1 |
Mus musculus (house mouse) | Tnfsf12 | NP_035744.1 |
Homo sapiens (human) | TNFSF12 | NP_003800.1 |
Bos taurus (cattle) | TNFSF12 | NP_001192072.1 |
The role of the tumor necrosis factor (TNF)-related weak inducer of apoptosis (TWEAK) in offspring exposed to prenatal hypoxia.
Reyes LM, Shah A, Quon A, Morton JS, Davidge ST
Journal of developmental origins of health and disease1-9(2017 Dec)
Long-term exercise training prevents mammary tumorigenesis-induced muscle wasting in rats through the regulation of TWEAK signalling.
Padr?o AI, Figueira AC, Faustino-Rocha AI, Gama A, Loureiro MM, Neuparth MJ, Moreira-Gon?alves D, Vitorino R, Amado F, Santos LL, Oliveira PA, Duarte JA, Ferreira R
Acta physiologica (Oxford, England)219(4)803-813(2017 Apr)
Comparative genomic analysis of eutherian tumor necrosis factor ligand genes.
Premzl M
Immunogenetics68(2)125-32(2016 Feb)
Endurance training prevents TWEAK but not myostatin-mediated cardiac remodelling in cancer cachexia.
Padr?o AI, Moreira-Gon?alves D, Oliveira PA, Teixeira C, Faustino-Rocha AI, Helguero L, Vitorino R, Santos LL, Amado F, Duarte JA, Ferreira R
Archives of biochemistry and biophysics56713-21(2015 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the present study provides molecular evidences that the interaction between endurance training and mammary tumorigenesis is mediated by TWEAK signalling
Title: Long-term exercise training prevents mammary tumorigenesis-induced muscle wasting in rats through the regulation of TWEAK signalling.
Endurance training prevents TWEAK but not myostatin-mediated cardiac remodelling in cancer cachexia
Title: Endurance training prevents TWEAK but not myostatin-mediated cardiac remodelling in cancer cachexia.
TWEAK acts as a potent astrocyte mitogen through the induction of a TGF-alpha/EGFR signaling pathway.
Title: Tumor necrosis factor-like weak inducer of apoptosis induces astrocyte proliferation through the activation of transforming-growth factor-?/epidermal growth factor receptor signaling pathway.
TWEAK/Fn14 axis increased cell proliferation and collagen synthesis by activating the NF-small ka, CyrillicB pathway and increasing MMP-9 activity
Title: TWEAK/Fn14 promotes the proliferation and collagen synthesis of rat cardiac fibroblasts via the NF-?B pathway.
Results suggest that the cardiac TWEAK/Fn14 pathway is modified in response to myocardial injury, inflammation and pressure overload.
Title: Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats.
The following Tnfsf12 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tnfsf12 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa09659 | |
Clone ID Related Accession (Same CDS sequence) | NM_001001513.2 | |
Accession Version | NM_001001513.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 750bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-03 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tumor necrosis factor ligand superfamily member 12 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079107.1. On Mar 27, 2005 this sequence version replaced NM_001001513.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079107.1, FQ221626.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00632252, SAMN01906352 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCCGCCC GTCGGAGCCA GAGGCGGAGG GGGCGCCGGG GGGAGCCGGG CACCGCCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001001513.2 |
CDS | 294..1043 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001001513.2 |
1 | ATGGCCGCCC GTCGGAGCCA GAGGCGGAGG GGGCGCCGGG GGGAGCCGGG CACCGCCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa33347 | |
Clone ID Related Accession (Same CDS sequence) | XM_006246745.3 | |
Accession Version | XM_006246745.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 753bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tumor necrosis factor ligand superfamily member 12 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006246745.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCGCCC GTCGGAGCCA GAGGCGGAGG GGGCGCCGGG GGGAGCCGGG CACCGCCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006246807.1 |
CDS | 354..1106 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006246745.3 |
1 | ATGGCCGCCC GTCGGAGCCA GAGGCGGAGG GGGCGCCGGG GGGAGCCGGG CACCGCCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The role of the tumor necrosis factor (TNF)-related weak inducer of apoptosis (TWEAK) in offspring exposed to prenatal hypoxia. |
Long-term exercise training prevents mammary tumorigenesis-induced muscle wasting in rats through the regulation of TWEAK signalling. |
Comparative genomic analysis of eutherian tumor necrosis factor ligand genes. |
Endurance training prevents TWEAK but not myostatin-mediated cardiac remodelling in cancer cachexia. |