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Thoc5 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Thoc5
Entrez Gene ID 360972
Full Name THO complex 5
Synonyms Fmip
General protein information
Preferred Names

THO complex 5

Names

THO complex subunit 5 homolog
Fms interacting protein
fms-interacting protein
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

14

14q21

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006251338.3 XP_006251400.1 THO complex subunit 5 homolog isoform X1
NM_001012153.1 NP_001012153.1 THO complex subunit 5 homolog
XM_006251339.3 XP_006251401.1 THO complex subunit 5 homolog isoform X2

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) THOC5 XP_001135376.2
Canis lupus familiaris (dog) THOC5 XP_534728.2
Danio rerio (zebrafish) thoc5 NP_997857.1
Homo sapiens (human) THOC5 NP_001002877.1
Bos taurus (cattle) THOC5 NP_001077185.1
Mus musculus (house mouse) Thoc5 NP_766026.1
Rattus norvegicus (Norway rat) Thoc5 NP_001012153.1
Gallus gallus (chicken) THOC5 NP_001006195.1
Drosophila melanogaster (fruit fly) thoc5 NP_611856.1
LOC714842 XP_002808014.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP004746 XP_001689094.1
Xenopus tropicalis (tropical clawed frog) thoc5 NP_001016827.1

Gene Ontology


Bibliography

Related articles in PubMed

The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming.
Wang L, Miao YL, Zheng X, Lackford B, Zhou B, Han L, Yao C, Ward JM, Burkholder A, Lipchina I, Fargo DC, Hochedlinger K, Shi Y, Williams CJ, Hu G
Cell stem cell13(6)676-90(2013 Dec)

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Grolimund L, Aeby E, Hamelin R, Armand F, Chiappe D, Moniatte M, Lingner J
Nature communications42848(2013)

mRNA export and the TREX complex.
Katahira J
Biochimica et biophysica acta1819(6)507-13(2012 Jun)

Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.
Dom?nguez-S?nchez MS, Barroso S, G?mez-Gonz?lez B, Luna R, Aguilera A
PLoS genetics7(12)e1002386(2011 Dec)

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo.
Mancini A, Niemann-Seyde SC, Pankow R, El Bounkari O, Klebba-F?rber S, Koch A, Jaworska E, Spooncer E, Gruber AD, Whetton AD, Tamura T
BMC biology81(2010 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Thoc5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Thoc5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa02489 NM_001012153.1
Latest version!		 Rattus norvegicus THO complex 5 (Thoc5), mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $391.30
$559.00
ORa36321 XM_006251338.3
Latest version!		 Rattus norvegicus THO complex 5 (Thoc5), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 12-14 $391.30
$559.00
ORa36322 XM_006251339.3
Latest version!		 Rattus norvegicus THO complex 5 (Thoc5), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 12-14 $391.30
$559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa02489
Clone ID Related Accession (Same CDS sequence) NM_001012153.1
Accession Version NM_001012153.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2049bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-16
Organism Rattus norvegicus(Norway rat)
Product THO complex subunit 5 homolog
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC079058.1. On Feb 11, 2005 this sequence version replaced XM_341250.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC079058.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
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361
421
481
541
601
661
721
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841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGTCATCAG AATCCAGCAA AAAAAGGAAA CCCAAAGTGA TCCGAAGTGA TGGAACCCCA 
ACTGAAGGGA AACGGAATCG ATCTGACACA GAGCAGGAAG GCAGATACTA TAGCGAGGAG 
GCTGAGGTTG ACCTGCGGGA CCCCGGCAGA GACTATGAGT TGTACAAGTA CACTTGCCAG 
GAGCTACAGA GGTTGATGGC TGAGATCCAG GACCTGAAGA GCAAGGGCAG CAAGGACGTG 
GCCATTGAAA TAGAAGAACG AAGGATCCAG AGCTGTGTGC ATTTCATGAC TCTAAAGAAG 
CTTAACCGAT TAGCCCATAT CAGGTTAAAG AAAGGAAGAG ATCAGACCCA CGAGGCCAAG 
CAGAAAGTCG ATGCCTACCA CCTACAGCTG CAGAACCTGC TCTACGAAGT GATGCACCTG 
CAGAAGGAGA TCACCAAGTG TCTGGAGTTC AAGTCAAAGC ATGAAGAAAT CGATCTGGTC 
AGTTTAGAGG AATTTTATTC AGAAGCTCCA CCAAACATCA GCAAGGCCGA GATCACCATG 
GGAGACCCTC ACCAACAGAC GCTGGCACGT TTGGACTGGG AGCTGGAGCA GCGGAAAAGG 
CTGGCAGAGA AGTACCGAGA GTGTCTGTCC AACAAGGAGA AGATCCTGAA GGAGATCGAG 
GTGAAGAAGG AGTATCTCAG CAGCCTCCAG CCCCGCCTCA ACAGCATCAT GCAGGCTTCC 
CTGCCGGTGC AAGAGTACCT GTTCATGCCA TTCGACCAGG CTCACAAGCA GTACGAGACC 
GCCAGGCACC TGCCGCCTCC CCTCTACGTG CTCTTTGTGC AGGCCACCGC ATACGGGCAG 
GCCTGTGATA AGACGTTGTC TGTGGCGATT GAAGGCAGTG TGGATGAAGC CAAAGCCCTT 
TTCAAGCCCC CCGAGGACTC CCAAGATGAT GAGAGTGACT CGGATGCTGA AGAGGAGCAG 
ACCACGAGGC GTCGGCCCAC ACTCGGGGTT CAGTTGGATG ATAAGCGCAA GGAGATGCTG 
AAAAGGCACC CGCTGTCTGT CCTGCTGGAT CTGAAGTGCA AAGACAACAG TGTGCTCCAT 
CTGACTTTCT TCTATCTCAT GAACCTCAAC ATCATGACAG TGAAAGCCAA AGTGACGACC 
GCCATGGAGC TGATCACCCC CATCAGTGCA GGCGACTTAC TGTCTCCTGA CTCGGTCTTG 
AGCTGCTTGT ATCCTGGAGA TCATGGAAAG AAAACTCCAA ATCCAGCCAA TCAGTATCAG 
TTTGATAAAG TTGGCATCCT GACTTTGAGA GACTATGTAC TTGAGTTAGG TCACCCCTAC 
TTGTGGGTAC AGAAGCTGGG TGGCCTCCAC TTCCCCAAAG AGCAGCCCCA GCACACGGTG 
ATGGCTGACC ACTCACAGAG CGCTAGCCAC ATGGAGACCA CCATGAAACT GCTCAAGACT 
AGGGTACAGT CCCGCCTGGC TCTCCACAAA CAGTTCGCAT CTCTGGAACA TGGCATTGTG 
CCAGTCACCA GCGAGTGCCA GTACCTCTTC CCTGCCAAGG TTGTTTCCCG ACTGGTAAAG 
TGGATGATAA TGGCCCATGA AGATTACATG GAGCTGCACT TCACTAAGGA CATTGTAGAG 
GCCGGCCTGG CTGGGGACAC CAACCTCTAC TACCTGGCGC TTATCGAAAG GGGAACAGCT 
AAGCTTCAGG CTGCTGTGGT ACTGAACCCT GGCTACTCCT CCATCCCACC TGTTTTCCGA 
CTCTGTCTAA ACTGGAAAGG GGAGAAAACC AACAGCAACG ATGACAACAT TCGGGCTATG 
GAGAGTGAAG TCAATGTGTG CTATCGGGAG CTCTGCGGCC CTCGGCCCAG TCACCAGCTC 
TTGACCAACC AGCTGCAGAG GCTGTGTGTG CTGCTGGATG TCTACCTGGA GACCGAGAGC 
CATGATGACA GTGTAGAGGG CCCCAAGGAA TTTCCCCAGG AGAAGATGTG CCTGCGGCTC 
TTTAGGGGTC CAAGTAGGAT GAAGCCGTTT AAATATAACC ACCCTCAGGG ATTCTTCAGC 
CACCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001012153.1
CDS21..2069
Translation

Target ORF information:

RefSeq Version NM_001012153.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus THO complex 5 (Thoc5), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001012153.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGTCATCAG AATCCAGCAA AAAAAGGAAA CCCAAAGTGA TCCGAAGTGA TGGAACCCCA 
ACTGAAGGGA AACGGAATCG ATCTGACACA GAGCAGGAAG GCAGATACTA TAGCGAGGAG 
GCTGAGGTTG ACCTGCGGGA CCCCGGCAGA GACTATGAGT TGTACAAGTA CACTTGCCAG 
GAGCTACAGA GGTTGATGGC TGAGATCCAG GACCTGAAGA GCAAGGGCAG CAAGGACGTG 
GCCATTGAAA TAGAAGAACG AAGGATCCAG AGCTGTGTGC ATTTCATGAC TCTAAAGAAG 
CTTAACCGAT TAGCCCATAT CAGGTTAAAG AAAGGAAGAG ATCAGACCCA CGAGGCCAAG 
CAGAAAGTCG ATGCCTACCA CCTACAGCTG CAGAACCTGC TCTACGAAGT GATGCACCTG 
CAGAAGGAGA TCACCAAGTG TCTGGAGTTC AAGTCAAAGC ATGAAGAAAT CGATCTGGTC 
AGTTTAGAGG AATTTTATTC AGAAGCTCCA CCAAACATCA GCAAGGCCGA GATCACCATG 
GGAGACCCTC ACCAACAGAC GCTGGCACGT TTGGACTGGG AGCTGGAGCA GCGGAAAAGG 
CTGGCAGAGA AGTACCGAGA GTGTCTGTCC AACAAGGAGA AGATCCTGAA GGAGATCGAG 
GTGAAGAAGG AGTATCTCAG CAGCCTCCAG CCCCGCCTCA ACAGCATCAT GCAGGCTTCC 
CTGCCGGTGC AAGAGTACCT GTTCATGCCA TTCGACCAGG CTCACAAGCA GTACGAGACC 
GCCAGGCACC TGCCGCCTCC CCTCTACGTG CTCTTTGTGC AGGCCACCGC ATACGGGCAG 
GCCTGTGATA AGACGTTGTC TGTGGCGATT GAAGGCAGTG TGGATGAAGC CAAAGCCCTT 
TTCAAGCCCC CCGAGGACTC CCAAGATGAT GAGAGTGACT CGGATGCTGA AGAGGAGCAG 
ACCACGAGGC GTCGGCCCAC ACTCGGGGTT CAGTTGGATG ATAAGCGCAA GGAGATGCTG 
AAAAGGCACC CGCTGTCTGT CCTGCTGGAT CTGAAGTGCA AAGACAACAG TGTGCTCCAT 
CTGACTTTCT TCTATCTCAT GAACCTCAAC ATCATGACAG TGAAAGCCAA AGTGACGACC 
GCCATGGAGC TGATCACCCC CATCAGTGCA GGCGACTTAC TGTCTCCTGA CTCGGTCTTG 
AGCTGCTTGT ATCCTGGAGA TCATGGAAAG AAAACTCCAA ATCCAGCCAA TCAGTATCAG 
TTTGATAAAG TTGGCATCCT GACTTTGAGA GACTATGTAC TTGAGTTAGG TCACCCCTAC 
TTGTGGGTAC AGAAGCTGGG TGGCCTCCAC TTCCCCAAAG AGCAGCCCCA GCACACGGTG 
ATGGCTGACC ACTCACAGAG CGCTAGCCAC ATGGAGACCA CCATGAAACT GCTCAAGACT 
AGGGTACAGT CCCGCCTGGC TCTCCACAAA CAGTTCGCAT CTCTGGAACA TGGCATTGTG 
CCAGTCACCA GCGAGTGCCA GTACCTCTTC CCTGCCAAGG TTGTTTCCCG ACTGGTAAAG 
TGGATGATAA TGGCCCATGA AGATTACATG GAGCTGCACT TCACTAAGGA CATTGTAGAG 
GCCGGCCTGG CTGGGGACAC CAACCTCTAC TACCTGGCGC TTATCGAAAG GGGAACAGCT 
AAGCTTCAGG CTGCTGTGGT ACTGAACCCT GGCTACTCCT CCATCCCACC TGTTTTCCGA 
CTCTGTCTAA ACTGGAAAGG GGAGAAAACC AACAGCAACG ATGACAACAT TCGGGCTATG 
GAGAGTGAAG TCAATGTGTG CTATCGGGAG CTCTGCGGCC CTCGGCCCAG TCACCAGCTC 
TTGACCAACC AGCTGCAGAG GCTGTGTGTG CTGCTGGATG TCTACCTGGA GACCGAGAGC 
CATGATGACA GTGTAGAGGG CCCCAAGGAA TTTCCCCAGG AGAAGATGTG CCTGCGGCTC 
TTTAGGGGTC CAAGTAGGAT GAAGCCGTTT AAATATAACC ACCCTCAGGG ATTCTTCAGC 
CACCGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa36321
Clone ID Related Accession (Same CDS sequence) XM_006251338.3
Accession Version XM_006251338.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2085bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product THO complex subunit 5 homolog isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251338.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
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481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGTCATCAG AATCCAGCAA AAAAAGGAAA CCCAAAGTGA TCCGAAGTGA TGGAACCCCA 
ACTGAAGGGA AACGGAATCG ATCTGACACA GAGCAGGAAG GCAGATACTA TAGCGAGGAG 
GCTGAGGTTG ACCTGCGGGA CCCCGGCAGA GACTATGAGT TGTACAAGTA CACTTGCCAG 
GAGCTACAGA GGTTGATGGC TGAGATCCAG GACCTGAAGA GCAAGGGCAG CAAGGACGTG 
GCCATTGAAA TAGAAGAACG AAGGATCCAG AGCTGTGTGC ATTTCATGAC TCTAAAGAAG 
CTTAACCGAT TAGCCCATAT CAGGTTAAAG AAAGGAAGAG ATCAGACCCA CGAGGCCAAG 
CAGAAAGTCG ATGCCTACCA CCTACAGCTG CAGAACCTGC TCTACGAAGT GATGCACCTG 
CAGAAGGAGA TCACCAAGTG TCTGGAGTTC AAGTCAAAGC ATGAAGAAAT CGATCTGGTC 
AGTTTAGAGG AATTTTATTC AGAAGCTCCA CCAAACATCA GCAAGGCCGA GATCACCATG 
GGAGACCCTC ACCAACAGAC GCTGGCACGT TTGGACTGGG AGCTGGAGCA GCGGAAAAGG 
CTGGCAGAGA AGTACCGAGA GTGTCTGTCC AACAAGGAGA AGATCCTGAA GGAGATCGAG 
GTGAAGAAGG AGTATCTCAG CAGCCTCCAG CCCCGCCTCA ACAGCATCAT GCAGGCTTCC 
CTGCCGGTGC AAGAGTACCT GTTCATGCCA TTCGACCAGG CTCACAAGCA GTACGAGACC 
GCCAGGCACC TGCCGCCTCC CCTCTACGTG CTCTTTGTGC AGGCCACCGC ATACGGGCAG 
GCCTGTGCTC ATATGACCTC CTCCCAGCCC CCTAGACAGG ATAAGACGTT GTCTGTGGCG 
ATTGAAGGCA GTGTGGATGA AGCCAAAGCC CTTTTCAAGC CCCCCGAGGA CTCCCAAGAT 
GATGAGAGTG ACTCGGATGC TGAAGAGGAG CAGACCACGA AGAGGCGTCG GCCCACACTC 
GGGGTTCAGT TGGATGATAA GCGCAAGGAG ATGCTGAAAA GGCACCCGCT GTCTGTCCTG 
CTGGATCTGA AGTGCAAAGA CAACAGTGTG CTCCATCTGA CTTTCTTCTA TCTCATGAAC 
CTCAACATCA TGACAGTGAA AGCCAAAGTG ACGACCGCCA TGGAGCTGAT CACCCCCATC 
AGTGCAGGCG ACTTACTGTC TCCTGACTCG GTCTTGAGCT GCTTGTATCC TGGAGATCAT 
GGAAAGAAAA CTCCAAATCC AGCCAATCAG TATCAGTTTG ATAAAGTTGG CATCCTGACT 
TTGAGAGACT ATGTACTTGA GTTAGGTCAC CCCTACTTGT GGGTACAGAA GCTGGGTGGC 
CTCCACTTCC CCAAAGAGCA GCCCCAGCAC ACGGTGATGG CTGACCACTC ACAGAGCGCT 
AGCCACATGG AGACCACCAT GAAACTGCTC AAGACTAGGG TACAGTCCCG CCTGGCTCTC 
CACAAACAGT TCGCATCTCT GGAACATGGC ATTGTGCCAG TCACCAGCGA GTGCCAGTAC 
CTCTTCCCTG CCAAGGTTGT TTCCCGACTG GTAAAGTGGA TGATAATGGC CCATGAAGAT 
TACATGGAGC TGCACTTCAC TAAGGACATT GTAGAGGCCG GCCTGGCTGG GGACACCAAC 
CTCTACTACC TGGCGCTTAT CGAAAGGGGA ACAGCTAAGC TTCAGGCTGC TGTGGTACTG 
AACCCTGGCT ACTCCTCCAT CCCACCTGTT TTCCGACTCT GTCTAAACTG GAAAGGGGAG 
AAAACCAACA GCAACGATGA CAACATTCGG GCTATGGAGA GTGAAGTCAA TGTGTGCTAT 
CGGGAGCTCT GCGGCCCTCG GCCCAGTCAC CAGCTCTTGA CCAACCAGCT GCAGAGGCTG 
TGTGTGCTGC TGGATGTCTA CCTGGAGACC GAGAGCCATG ATGACAGTGT AGAGGGCCCC 
AAGGAATTTC CCCAGGAGAA GATGTGCCTG CGGCTCTTTA GGGGTCCAAG TAGGATGAAG 
CCGTTTAAAT ATAACCACCC TCAGGGATTC TTCAGCCACC GCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006251400.1
CDS117..2201
Translation

Target ORF information:

RefSeq Version XM_006251338.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus THO complex 5 (Thoc5), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006251338.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGTCATCAG AATCCAGCAA AAAAAGGAAA CCCAAAGTGA TCCGAAGTGA TGGAACCCCA 
ACTGAAGGGA AACGGAATCG ATCTGACACA GAGCAGGAAG GCAGATACTA TAGCGAGGAG 
GCTGAGGTTG ACCTGCGGGA CCCCGGCAGA GACTATGAGT TGTACAAGTA CACTTGCCAG 
GAGCTACAGA GGTTGATGGC TGAGATCCAG GACCTGAAGA GCAAGGGCAG CAAGGACGTG 
GCCATTGAAA TAGAAGAACG AAGGATCCAG AGCTGTGTGC ATTTCATGAC TCTAAAGAAG 
CTTAACCGAT TAGCCCATAT CAGGTTAAAG AAAGGAAGAG ATCAGACCCA CGAGGCCAAG 
CAGAAAGTCG ATGCCTACCA CCTACAGCTG CAGAACCTGC TCTACGAAGT GATGCACCTG 
CAGAAGGAGA TCACCAAGTG TCTGGAGTTC AAGTCAAAGC ATGAAGAAAT CGATCTGGTC 
AGTTTAGAGG AATTTTATTC AGAAGCTCCA CCAAACATCA GCAAGGCCGA GATCACCATG 
GGAGACCCTC ACCAACAGAC GCTGGCACGT TTGGACTGGG AGCTGGAGCA GCGGAAAAGG 
CTGGCAGAGA AGTACCGAGA GTGTCTGTCC AACAAGGAGA AGATCCTGAA GGAGATCGAG 
GTGAAGAAGG AGTATCTCAG CAGCCTCCAG CCCCGCCTCA ACAGCATCAT GCAGGCTTCC 
CTGCCGGTGC AAGAGTACCT GTTCATGCCA TTCGACCAGG CTCACAAGCA GTACGAGACC 
GCCAGGCACC TGCCGCCTCC CCTCTACGTG CTCTTTGTGC AGGCCACCGC ATACGGGCAG 
GCCTGTGCTC ATATGACCTC CTCCCAGCCC CCTAGACAGG ATAAGACGTT GTCTGTGGCG 
ATTGAAGGCA GTGTGGATGA AGCCAAAGCC CTTTTCAAGC CCCCCGAGGA CTCCCAAGAT 
GATGAGAGTG ACTCGGATGC TGAAGAGGAG CAGACCACGA AGAGGCGTCG GCCCACACTC 
GGGGTTCAGT TGGATGATAA GCGCAAGGAG ATGCTGAAAA GGCACCCGCT GTCTGTCCTG 
CTGGATCTGA AGTGCAAAGA CAACAGTGTG CTCCATCTGA CTTTCTTCTA TCTCATGAAC 
CTCAACATCA TGACAGTGAA AGCCAAAGTG ACGACCGCCA TGGAGCTGAT CACCCCCATC 
AGTGCAGGCG ACTTACTGTC TCCTGACTCG GTCTTGAGCT GCTTGTATCC TGGAGATCAT 
GGAAAGAAAA CTCCAAATCC AGCCAATCAG TATCAGTTTG ATAAAGTTGG CATCCTGACT 
TTGAGAGACT ATGTACTTGA GTTAGGTCAC CCCTACTTGT GGGTACAGAA GCTGGGTGGC 
CTCCACTTCC CCAAAGAGCA GCCCCAGCAC ACGGTGATGG CTGACCACTC ACAGAGCGCT 
AGCCACATGG AGACCACCAT GAAACTGCTC AAGACTAGGG TACAGTCCCG CCTGGCTCTC 
CACAAACAGT TCGCATCTCT GGAACATGGC ATTGTGCCAG TCACCAGCGA GTGCCAGTAC 
CTCTTCCCTG CCAAGGTTGT TTCCCGACTG GTAAAGTGGA TGATAATGGC CCATGAAGAT 
TACATGGAGC TGCACTTCAC TAAGGACATT GTAGAGGCCG GCCTGGCTGG GGACACCAAC 
CTCTACTACC TGGCGCTTAT CGAAAGGGGA ACAGCTAAGC TTCAGGCTGC TGTGGTACTG 
AACCCTGGCT ACTCCTCCAT CCCACCTGTT TTCCGACTCT GTCTAAACTG GAAAGGGGAG 
AAAACCAACA GCAACGATGA CAACATTCGG GCTATGGAGA GTGAAGTCAA TGTGTGCTAT 
CGGGAGCTCT GCGGCCCTCG GCCCAGTCAC CAGCTCTTGA CCAACCAGCT GCAGAGGCTG 
TGTGTGCTGC TGGATGTCTA CCTGGAGACC GAGAGCCATG ATGACAGTGT AGAGGGCCCC 
AAGGAATTTC CCCAGGAGAA GATGTGCCTG CGGCTCTTTA GGGGTCCAAG TAGGATGAAG 
CCGTTTAAAT ATAACCACCC TCAGGGATTC TTCAGCCACC GCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa36322
Clone ID Related Accession (Same CDS sequence) XM_006251339.3
Accession Version XM_006251339.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2052bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product THO complex subunit 5 homolog isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005113.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006251339.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGTCATCAG AATCCAGCAA AAAAAGGAAA CCCAAAGTGA TCCGAAGTGA TGGAACCCCA 
ACTGAAGGGA AACGGAATCG ATCTGACACA GAGCAGGAAG GCAGATACTA TAGCGAGGAG 
GCTGAGGTTG ACCTGCGGGA CCCCGGCAGA GACTATGAGT TGTACAAGTA CACTTGCCAG 
GAGCTACAGA GGTTGATGGC TGAGATCCAG GACCTGAAGA GCAAGGGCAG CAAGGACGTG 
GCCATTGAAA TAGAAGAACG AAGGATCCAG AGCTGTGTGC ATTTCATGAC TCTAAAGAAG 
CTTAACCGAT TAGCCCATAT CAGGTTAAAG AAAGGAAGAG ATCAGACCCA CGAGGCCAAG 
CAGAAAGTCG ATGCCTACCA CCTACAGCTG CAGAACCTGC TCTACGAAGT GATGCACCTG 
CAGAAGGAGA TCACCAAGTG TCTGGAGTTC AAGTCAAAGC ATGAAGAAAT CGATCTGGTC 
AGTTTAGAGG AATTTTATTC AGAAGCTCCA CCAAACATCA GCAAGGCCGA GATCACCATG 
GGAGACCCTC ACCAACAGAC GCTGGCACGT TTGGACTGGG AGCTGGAGCA GCGGAAAAGG 
CTGGCAGAGA AGTACCGAGA GTGTCTGTCC AACAAGGAGA AGATCCTGAA GGAGATCGAG 
GTGAAGAAGG AGTATCTCAG CAGCCTCCAG CCCCGCCTCA ACAGCATCAT GCAGGCTTCC 
CTGCCGGTGC AAGAGTACCT GTTCATGCCA TTCGACCAGG CTCACAAGCA GTACGAGACC 
GCCAGGCACC TGCCGCCTCC CCTCTACGTG CTCTTTGTGC AGGCCACCGC ATACGGGCAG 
GCCTGTGATA AGACGTTGTC TGTGGCGATT GAAGGCAGTG TGGATGAAGC CAAAGCCCTT 
TTCAAGCCCC CCGAGGACTC CCAAGATGAT GAGAGTGACT CGGATGCTGA AGAGGAGCAG 
ACCACGAAGA GGCGTCGGCC CACACTCGGG GTTCAGTTGG ATGATAAGCG CAAGGAGATG 
CTGAAAAGGC ACCCGCTGTC TGTCCTGCTG GATCTGAAGT GCAAAGACAA CAGTGTGCTC 
CATCTGACTT TCTTCTATCT CATGAACCTC AACATCATGA CAGTGAAAGC CAAAGTGACG 
ACCGCCATGG AGCTGATCAC CCCCATCAGT GCAGGCGACT TACTGTCTCC TGACTCGGTC 
TTGAGCTGCT TGTATCCTGG AGATCATGGA AAGAAAACTC CAAATCCAGC CAATCAGTAT 
CAGTTTGATA AAGTTGGCAT CCTGACTTTG AGAGACTATG TACTTGAGTT AGGTCACCCC 
TACTTGTGGG TACAGAAGCT GGGTGGCCTC CACTTCCCCA AAGAGCAGCC CCAGCACACG 
GTGATGGCTG ACCACTCACA GAGCGCTAGC CACATGGAGA CCACCATGAA ACTGCTCAAG 
ACTAGGGTAC AGTCCCGCCT GGCTCTCCAC AAACAGTTCG CATCTCTGGA ACATGGCATT 
GTGCCAGTCA CCAGCGAGTG CCAGTACCTC TTCCCTGCCA AGGTTGTTTC CCGACTGGTA 
AAGTGGATGA TAATGGCCCA TGAAGATTAC ATGGAGCTGC ACTTCACTAA GGACATTGTA 
GAGGCCGGCC TGGCTGGGGA CACCAACCTC TACTACCTGG CGCTTATCGA AAGGGGAACA 
GCTAAGCTTC AGGCTGCTGT GGTACTGAAC CCTGGCTACT CCTCCATCCC ACCTGTTTTC 
CGACTCTGTC TAAACTGGAA AGGGGAGAAA ACCAACAGCA ACGATGACAA CATTCGGGCT 
ATGGAGAGTG AAGTCAATGT GTGCTATCGG GAGCTCTGCG GCCCTCGGCC CAGTCACCAG 
CTCTTGACCA ACCAGCTGCA GAGGCTGTGT GTGCTGCTGG ATGTCTACCT GGAGACCGAG 
AGCCATGATG ACAGTGTAGA GGGCCCCAAG GAATTTCCCC AGGAGAAGAT GTGCCTGCGG 
CTCTTTAGGG GTCCAAGTAG GATGAAGCCG TTTAAATATA ACCACCCTCA GGGATTCTTC 
AGCCACCGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006251401.1
CDS117..2168
Translation

Target ORF information:

RefSeq Version XM_006251339.3
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus THO complex 5 (Thoc5), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006251339.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
ATGTCATCAG AATCCAGCAA AAAAAGGAAA CCCAAAGTGA TCCGAAGTGA TGGAACCCCA 
ACTGAAGGGA AACGGAATCG ATCTGACACA GAGCAGGAAG GCAGATACTA TAGCGAGGAG 
GCTGAGGTTG ACCTGCGGGA CCCCGGCAGA GACTATGAGT TGTACAAGTA CACTTGCCAG 
GAGCTACAGA GGTTGATGGC TGAGATCCAG GACCTGAAGA GCAAGGGCAG CAAGGACGTG 
GCCATTGAAA TAGAAGAACG AAGGATCCAG AGCTGTGTGC ATTTCATGAC TCTAAAGAAG 
CTTAACCGAT TAGCCCATAT CAGGTTAAAG AAAGGAAGAG ATCAGACCCA CGAGGCCAAG 
CAGAAAGTCG ATGCCTACCA CCTACAGCTG CAGAACCTGC TCTACGAAGT GATGCACCTG 
CAGAAGGAGA TCACCAAGTG TCTGGAGTTC AAGTCAAAGC ATGAAGAAAT CGATCTGGTC 
AGTTTAGAGG AATTTTATTC AGAAGCTCCA CCAAACATCA GCAAGGCCGA GATCACCATG 
GGAGACCCTC ACCAACAGAC GCTGGCACGT TTGGACTGGG AGCTGGAGCA GCGGAAAAGG 
CTGGCAGAGA AGTACCGAGA GTGTCTGTCC AACAAGGAGA AGATCCTGAA GGAGATCGAG 
GTGAAGAAGG AGTATCTCAG CAGCCTCCAG CCCCGCCTCA ACAGCATCAT GCAGGCTTCC 
CTGCCGGTGC AAGAGTACCT GTTCATGCCA TTCGACCAGG CTCACAAGCA GTACGAGACC 
GCCAGGCACC TGCCGCCTCC CCTCTACGTG CTCTTTGTGC AGGCCACCGC ATACGGGCAG 
GCCTGTGATA AGACGTTGTC TGTGGCGATT GAAGGCAGTG TGGATGAAGC CAAAGCCCTT 
TTCAAGCCCC CCGAGGACTC CCAAGATGAT GAGAGTGACT CGGATGCTGA AGAGGAGCAG 
ACCACGAAGA GGCGTCGGCC CACACTCGGG GTTCAGTTGG ATGATAAGCG CAAGGAGATG 
CTGAAAAGGC ACCCGCTGTC TGTCCTGCTG GATCTGAAGT GCAAAGACAA CAGTGTGCTC 
CATCTGACTT TCTTCTATCT CATGAACCTC AACATCATGA CAGTGAAAGC CAAAGTGACG 
ACCGCCATGG AGCTGATCAC CCCCATCAGT GCAGGCGACT TACTGTCTCC TGACTCGGTC 
TTGAGCTGCT TGTATCCTGG AGATCATGGA AAGAAAACTC CAAATCCAGC CAATCAGTAT 
CAGTTTGATA AAGTTGGCAT CCTGACTTTG AGAGACTATG TACTTGAGTT AGGTCACCCC 
TACTTGTGGG TACAGAAGCT GGGTGGCCTC CACTTCCCCA AAGAGCAGCC CCAGCACACG 
GTGATGGCTG ACCACTCACA GAGCGCTAGC CACATGGAGA CCACCATGAA ACTGCTCAAG 
ACTAGGGTAC AGTCCCGCCT GGCTCTCCAC AAACAGTTCG CATCTCTGGA ACATGGCATT 
GTGCCAGTCA CCAGCGAGTG CCAGTACCTC TTCCCTGCCA AGGTTGTTTC CCGACTGGTA 
AAGTGGATGA TAATGGCCCA TGAAGATTAC ATGGAGCTGC ACTTCACTAA GGACATTGTA 
GAGGCCGGCC TGGCTGGGGA CACCAACCTC TACTACCTGG CGCTTATCGA AAGGGGAACA 
GCTAAGCTTC AGGCTGCTGT GGTACTGAAC CCTGGCTACT CCTCCATCCC ACCTGTTTTC 
CGACTCTGTC TAAACTGGAA AGGGGAGAAA ACCAACAGCA ACGATGACAA CATTCGGGCT 
ATGGAGAGTG AAGTCAATGT GTGCTATCGG GAGCTCTGCG GCCCTCGGCC CAGTCACCAG 
CTCTTGACCA ACCAGCTGCA GAGGCTGTGT GTGCTGCTGG ATGTCTACCT GGAGACCGAG 
AGCCATGATG ACAGTGTAGA GGGCCCCAAG GAATTTCCCC AGGAGAAGAT GTGCCTGCGG 
CTCTTTAGGG GTCCAAGTAG GATGAAGCCG TTTAAATATA ACCACCCTCA GGGATTCTTC 
AGCCACCGCT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

The THO complex regulates pluripotency gene mRNA export and controls embryonic stem cell self-renewal and somatic cell reprogramming.
Cell stem cell13(6)676-90(2013 Dec)
Wang L,Miao YL,Zheng X,Lackford B,Zhou B,Han L,Yao C,Ward JM,Burkholder A,Lipchina I,Fargo DC,Hochedlinger K,Shi Y,Williams CJ,Hu G


book

A quantitative telomeric chromatin isolation protocol identifies different telomeric states.
Nature communications42848(2013)
Grolimund L,Aeby E,Hamelin R,Armand F,Chiappe D,Moniatte M,Lingner J


book

mRNA export and the TREX complex.
Biochimica et biophysica acta1819(6)507-13(2012 Jun)
Katahira J


book

Genome instability and transcription elongation impairment in human cells depleted of THO/TREX.
PLoS genetics7(12)e1002386(2011 Dec)
Dom?nguez-S?nchez MS,Barroso S,G?mez-Gonz?lez B,Luna R,Aguilera A


book

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo.
BMC biology81(2010 Jan)
Mancini A,Niemann-Seyde SC,Pankow R,El Bounkari O,Klebba-F?rber S,Koch A,Jaworska E,Spooncer E,Gruber AD,Whetton AD,Tamura T