Gene Symbol | THOC5 |
Entrez Gene ID | 8563 |
Full Name | THO complex 5 |
Synonyms | C22orf19,Fmip,PK1.3,fSAP79 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » THOC5 cDNA ORF clone
gRNAs
Gene Symbol | THOC5 |
Entrez Gene ID | 8563 |
Full Name | THO complex 5 |
Synonyms | C22orf19,Fmip,PK1.3,fSAP79 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_003678.4 | NP_003669.4 | THO complex subunit 5 homolog |
XM_005261798.1 | XP_005261855.1 | THO complex subunit 5 homolog isoform X1 |
XM_006724347.1 | XP_006724410.1 | THO complex subunit 5 homolog isoform X1 |
XM_024452296.1 | XP_024308064.1 | THO complex subunit 5 homolog isoform X2 |
NM_001002878.1 | NP_001002878.1 | THO complex subunit 5 homolog |
NM_001002877.2 | NP_001002877.1 | THO complex subunit 5 homolog |
NM_001002877.1 | NP_001002877.1 | THO complex subunit 5 homolog |
XM_005261797.1 | XP_005261854.1 | THO complex subunit 5 homolog isoform X1 |
XM_005261799.1 | XP_005261856.1 | THO complex subunit 5 homolog isoform X1 |
XM_005261801.4 | XP_005261858.1 | THO complex subunit 5 homolog isoform X3 |
XM_017029027.1 | XP_016884516.1 | THO complex subunit 5 homolog isoform X1 |
XM_005261801.3 | XP_005261858.1 | THO complex subunit 5 homolog isoform X2 |
NM_001002879.1 | NP_001002879.1 | THO complex subunit 5 homolog |
XM_017029027.2 | XP_016884516.1 | THO complex subunit 5 homolog isoform X1 |
NM_003678.5 | NP_003669.4 | THO complex subunit 5 homolog |
Pan troglodytes (chimpanzee) | THOC5 | XP_001135376.2 |
Canis lupus familiaris (dog) | THOC5 | XP_534728.2 |
Danio rerio (zebrafish) | thoc5 | NP_997857.1 |
Homo sapiens (human) | THOC5 | NP_001002877.1 |
Bos taurus (cattle) | THOC5 | NP_001077185.1 |
Mus musculus (house mouse) | Thoc5 | NP_766026.1 |
Rattus norvegicus (Norway rat) | Thoc5 | NP_001012153.1 |
Gallus gallus (chicken) | THOC5 | NP_001006195.1 |
Drosophila melanogaster (fruit fly) | thoc5 | NP_611856.1 |
LOC714842 | XP_002808014.1 | |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004746 | XP_001689094.1 |
Xenopus tropicalis (tropical clawed frog) | thoc5 | NP_001016827.1 |
Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)
Depletion of three combined THOC5 mRNA export protein target genes synergistically induces human hepatocellular carcinoma cell death.
Saran S, Tran DD, Ewald F, Koch A, Hoffmann A, Koch M, Nashan B, Tamura T
Oncogene35(29)3872-9(2016 Jul)
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)
mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3.
Gebhardt A, Habjan M, Benda C, Meiler A, Haas DA, Hein MY, Mann A, Mann M, Habermann B, Pichlmair A
Nature communications68192(2015 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest that the suppression of the multiple THOC5 target genes may represent a novel strategy for hepatocellular carcinoma (HCC) therapy.
Title: Depletion of three combined THOC5 mRNA export protein target genes synergistically induces human hepatocellular carcinoma cell death.
THOC5 to be a novel gene involved in the regulation of serum HDL-C levels
Title: THOC5: a novel gene involved in HDL-cholesterol metabolism.
Authors suggest a model in which human Thoc5 controls polyadenylation site choice through the co-transcriptional loading of CFIm68 onto target genes.
Title: Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I.
show that THOC5 Y225 phosphorylation governs mRNA binding. In addition, CXCL12 is shown to induce THOC5 Y225 phosphorylation, and site-directed mutagenesis demonstrates that this modulates motile response
Title: A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.
show here that DNA damage drastically decreased the cytoplasmic pool of a set of THOC5-dependent mRNAs and impaired the THOC5/mRNA complex formation
Title: An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5.
The following THOC5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the THOC5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OHu53727 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261801.4 , XM_005261801.3 | |
Accession Version | XM_005261801.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005261801.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAAGA GGCACCCACT GTCTGTCATG CTCGACCTGA AGTGCAAAGA TGACAGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261858.1 |
CDS | 1241..2275 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTGAAGA GGCACCCACT GTCTGTCATG CTCGACCTGA AGTGCAAAGA TGACAGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53727 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261801.4 , XM_005261801.3 | |
Accession Version | XM_005261801.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1035bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005261801.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGAAGA GGCACCCACT GTCTGTCATG CTCGACCTGA AGTGCAAAGA TGACAGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261858.1 |
CDS | 1212..2246 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGCTGAAGA GGCACCCACT GTCTGTCATG CTCGACCTGA AGTGCAAAGA TGACAGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25415 | |
Clone ID Related Accession (Same CDS sequence) | NM_003678.4 , XM_024452296.1 , NM_001002878.1 , NM_001002877.2 , NM_001002877.1 , NM_001002879.1 , NM_003678.5 | |
Accession Version | NM_003678.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-15 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX404329.2, CR456542.1, BX400943.2, AB023200.1 and BQ184247.1. On Aug 4, 2004 this sequence version replaced NM_003678.3. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.142158.1, SRR1803615.75622.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_003669.4 |
CDS | 89..2140 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25415 | |
Clone ID Related Accession (Same CDS sequence) | NM_003678.4 , XM_024452296.1 , NM_001002878.1 , NM_001002877.2 , NM_001002877.1 , NM_001002879.1 , NM_003678.5 | |
Accession Version | NM_001002878.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-09 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CN387648.1, BX404329.2, CR456542.1, BX400943.2, AB023200.1 and BQ184247.1. Transcript Variant: This variant (1) represents the longest transcript. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.231505.1, SRR1803612.79886.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001002878.1 |
CDS | 336..2387 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25415 | |
Clone ID Related Accession (Same CDS sequence) | NM_003678.4 , XM_024452296.1 , NM_001002878.1 , NM_001002877.2 , NM_001002877.1 , NM_001002879.1 , NM_003678.5 | |
Accession Version | NM_001002877.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-09 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC005529.7, BX404329.2, BX381026.2, CR456542.1, BX400943.2, AB023200.1 and BQ184247.1. On Jun 2, 2019 this sequence version replaced NM_001002877.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.127012.1, SRR1803617.226157.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001002877.1 |
CDS | 215..2266 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25415 | |
Clone ID Related Accession (Same CDS sequence) | NM_003678.4 , XM_024452296.1 , NM_001002878.1 , NM_001002877.2 , NM_001002877.1 , NM_001002879.1 , NM_003678.5 | |
Accession Version | NM_001002877.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-15 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BX404329.2, BX381026.2, CR456542.1, BX400943.2, AB023200.1 and BQ184247.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.127012.1, SRR5189667.138030.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001002877.1 |
CDS | 205..2256 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25415 | |
Clone ID Related Accession (Same CDS sequence) | NM_003678.4 , XM_024452296.1 , NM_001002878.1 , NM_001002877.2 , NM_001002877.1 , NM_001002879.1 , NM_003678.5 | |
Accession Version | NM_001002879.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-10 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU187531.1, BX404329.2, CR456542.1, BX400943.2, AB023200.1 and BQ184247.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: AB023200.1, SRR1803612.129529.1 [ECO:0000331] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001002879.1 |
CDS | 220..2271 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25415 | |
Clone ID Related Accession (Same CDS sequence) | NM_003678.4 , XM_024452296.1 , NM_001002878.1 , NM_001002877.2 , NM_001002877.1 , NM_001002879.1 , NM_003678.5 | |
Accession Version | NM_003678.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-09 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC005529.7, BX404329.2, CR456542.1, BX400943.2, AB023200.1 and BQ184247.1. On Jun 2, 2019 this sequence version replaced NM_003678.4. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. All four variants encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB023200.1, SRR1660807.93699.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_003669.4 |
CDS | 99..2150 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25415 | |
Clone ID Related Accession (Same CDS sequence) | NM_003678.4 , XM_024452296.1 , NM_001002878.1 , NM_001002877.2 , NM_001002877.1 , NM_001002879.1 , NM_003678.5 | |
Accession Version | XM_024452296.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2052bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_024308064.1 |
CDS | 207..2258 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53725 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261798.1 , XM_006724347.1 , XM_005261797.1 , XM_005261799.1 , XM_017029027.1 , XM_017029027.2 | |
Accession Version | XM_005261798.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261855.1 |
CDS | 218..2302 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53725 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261798.1 , XM_006724347.1 , XM_005261797.1 , XM_005261799.1 , XM_017029027.1 , XM_017029027.2 | |
Accession Version | XM_006724347.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006724410.1 |
CDS | 332..2416 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53725 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261798.1 , XM_006724347.1 , XM_005261797.1 , XM_005261799.1 , XM_017029027.1 , XM_017029027.2 | |
Accession Version | XM_005261797.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261854.1 |
CDS | 102..2186 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53725 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261798.1 , XM_006724347.1 , XM_005261797.1 , XM_005261799.1 , XM_017029027.1 , XM_017029027.2 | |
Accession Version | XM_005261799.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261856.1 |
CDS | 245..2329 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53725 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261798.1 , XM_006724347.1 , XM_005261797.1 , XM_005261799.1 , XM_017029027.1 , XM_017029027.2 | |
Accession Version | XM_017029027.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016884516.1 |
CDS | 704..2788 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53725 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261798.1 , XM_006724347.1 , XM_005261797.1 , XM_005261799.1 , XM_017029027.1 , XM_017029027.2 | |
Accession Version | XM_017029027.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | THO complex subunit 5 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017029027.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016884516.1 |
CDS | 207..2291 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCATCAG AATCGAGCAA AAAACGGAAG CCCAAAGTGA TCCGAAGCGA TGGAGCCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Architecture of the human interactome defines protein communities and disease networks. |
Depletion of three combined THOC5 mRNA export protein target genes synergistically induces human hepatocellular carcinoma cell death. |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. |
mRNA export through an additional cap-binding complex consisting of NCBP1 and NCBP3. |