Melk cDNA ORF clone, Rattus norvegicus(Norway rat)
Gene Symbol | Melk |
Entrez Gene ID | 362510 |
Full Name | maternal embryonic leucine zipper kinase |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_001108662.1 | NP_001102132.1 | maternal embryonic leucine zipper kinase |
XM_006238082.3 | XP_006238144.1 | maternal embryonic leucine zipper kinase isoform X1 |

Canis lupus familiaris (dog) | MELK | XP_538730.2 |
Gallus gallus (chicken) | MELK | NP_001026680.1 |
Xenopus tropicalis (tropical clawed frog) | melk | NP_001016390.1 |
Rattus norvegicus (Norway rat) | Melk | NP_001102132.1 |
Pan troglodytes (chimpanzee) | MELK | XP_001169038.1 |
Mus musculus (house mouse) | Melk | NP_034920.2 |
Danio rerio (zebrafish) | melk | NP_996771.2 |
Arabidopsis thaliana (thale cress) | CIPK7 | NP_188940.1 |
Homo sapiens (human) | MELK | NP_055606.1 |
MELK | XP_001115076.2 | |
Bos taurus (cattle) | MELK | NP_001104730.1 |
Caenorhabditis elegans (roundworm) | pig-1 | NP_001023420.2 |
Arabidopsis thaliana (thale cress) | CIPK4 | NP_193194.1 |

Related articles in PubMed
Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids.
Moravcevic K, Mendrola JM, Schmitz KR, Wang YH, Slochower D, Janmey PA, Lemmon MA
Cell143(6)966-77(2010 Dec)
Defining the membrane proteome of NK cells.
Ghosh D, Lippert D, Krokhin O, Cortens JP, Wilkins JA
Journal of mass spectrometry : JMS45(1)1-25(2010 Jan)
Murine protein serine/threonine kinase 38 activates apoptosis signal-regulating kinase 1 via Thr 838 phosphorylation.
Jung H, Seong HA, Ha H
The Journal of biological chemistry283(50)34541-53(2008 Dec)
Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
Lin ML, Park JH, Nishidate T, Nakamura Y, Katagiri T
Breast cancer research : BCR9(1)R17(2007)
Substrate specificity and activity regulation of protein kinase MELK.
Beullens M, Vancauwenbergh S, Morrice N, Derua R, Ceulemans H, Waelkens E, Bollen M
The Journal of biological chemistry280(48)40003-11(2005 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Melk gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Melk cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa08064 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108662.1 | |
Accession Version | NM_001108662.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | maternal embryonic leucine zipper kinase | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473962.1. On or before Oct 4, 2007 this sequence version replaced XM_342828.3, XM_001064686.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA2689604, SAMN01906347 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGAAAGATT ATGACGAGCT CCTTAAATAC TATGAATTAT ATGAAACTAT TGGGACAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102132.1 |
CDS | 126..1214 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGAAAGATT ATGACGAGCT CCTTAAATAC TATGAATTAT ATGAAACTAT TGGGACAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa28150 | |
Clone ID Related Accession (Same CDS sequence) | XM_006238082.3 | |
Accession Version | XM_006238082.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1932bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | maternal embryonic leucine zipper kinase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006238082.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAAGATT ATGACGAGCT CCTTAAATAC TATGAATTAT ATGAAACTAT TGGGACAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006238144.1 |
CDS | 181..2112 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGAAAGATT ATGACGAGCT CCTTAAATAC TATGAATTAT ATGAAACTAT TGGGACAGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids. |
![]() |
Defining the membrane proteome of NK cells. |
![]() |
Murine protein serine/threonine kinase 38 activates apoptosis signal-regulating kinase 1 via Thr 838 phosphorylation. |
![]() |
Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family. |
![]() |
Substrate specificity and activity regulation of protein kinase MELK. |