| Gene Symbol | Wdr48 |
| Entrez Gene ID | 363164 |
| Full Name | WD repeat domain 48 |
| Synonyms | RGD1309702 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
gRNAs
The following Wdr48 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Wdr48 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa03100 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001135895.2 | |
| Accession Version | NM_001135895.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2031bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-05-27 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | WD repeat-containing protein 48 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07071739.1. On Jul 11, 2009 this sequence version replaced NM_001135895.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGCGGCCC ATCACCGGCA GAACACAGCC GGGCGGAGAA AAGTGCAGGT TTCCTATGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001129367.1 |
| CDS | 20..2050 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001135895.2 |
1 | ATGGCGGCCC ATCACCGGCA GAACACAGCC GGGCGGAGAA AAGTGCAGGT TTCCTATGTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa62474 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017595770.1 | |
| Accession Version | XM_017595770.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2076bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | WD repeat-containing protein 48 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGCCTAC TGCCCGCTCA CCTGCCTCTG CTCTCGGCCG CCTTCCTCCG GAACAGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017451259.1 |
| CDS | 93..2168 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017595770.1 |
1 | ATGGGCCTAC TGCCCGCTCA CCTGCCTCTG CTCTCGGCCG CCTTCCTCCG GAACAGCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
WD repeat protein WDR48 in complex with deubiquitinase USP12 suppresses Akt-dependent cell survival signaling by stabilizing PH domain leucine-rich repeat protein phosphatase 1 (PHLPP1). |
Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice. |
UAF1 is a subunit of multiple deubiquitinating enzyme complexes. |
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. |
