Gene Symbol | Tmeff2 |
Entrez Gene ID | 363228 |
Full Name | transmembrane protein with EGF-like and two follistatin-like domains 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
ORF » Species Summary » Rattus norvegicus » Tmeff2 cDNA ORF clone
Gene Symbol | Tmeff2 |
Entrez Gene ID | 363228 |
Full Name | transmembrane protein with EGF-like and two follistatin-like domains 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017596515.1 | XP_017452004.1 | tomoregulin-2 isoform X1 |
NM_001108795.1 | NP_001102265.1 | tomoregulin-2 |
The TMEFF2 tumor suppressor modulates integrin expression, RhoA activation and migration of prostate cancer cells.
Chen X, Corbin JM, Tipton GJ, Yang LV, Asch AS, Ruiz-Echevarr?a MJ
Biochimica et biophysica acta1843(6)1216-24(2014 Jun)
Refined mapping of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models.
Kumarasamy S, Gopalakrishnan K, Toland EJ, Yerga-Woolwine S, Farms P, Morgan EE, Joe B
Hypertension research : official journal of the Japanese Society of Hypertension34(12)1263-70(2011 Dec)
Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo.
Chen Q, Watson JT, Marengo SR, Decker KS, Coleman I, Nelson PS, Sikes RA
Cancer letters244(2)274-88(2006 Dec)
Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer.
Afar DE, Bhaskar V, Ibsen E, Breinberg D, Henshall SM, Kench JG, Drobnjak M, Powers R, Wong M, Evangelista F, O'Hara C, Powers D, DuBridge RB, Caras I, Winter R, Anderson T, Solvason N, Stricker PD, Cordon-Cardo C, Scher HI, Grygiel JJ, Sutherland RL, Murray R, Ramakrishnan V, Law DA
Molecular cancer therapeutics3(8)921-32(2004 Aug)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Tmeff2 can be prioritized as a candidate gene for hypertension and associated cardiac hypertrophy in both rats and in humans
Title: Refined mapping of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models.
The following Tmeff2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tmeff2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13489 | |
Clone ID Related Accession (Same CDS sequence) | NM_001108795.1 | |
Accession Version | NM_001108795.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tomoregulin-2 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473965.2. On or before Oct 4, 2007 this sequence version replaced XM_343566.3, XM_001064388.1. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGTGCTGT GGGAGTCCCC GCGGCAGTGC AGCAGCTGGA CACTTTGCGA GGGCTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001102265.1 |
CDS | 431..1252 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001108795.1 |
1 | ATGGTGCTGT GGGAGTCCCC GCGGCAGTGC AGCAGCTGGA CACTTTGCGA GGGCTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa62806 | |
Clone ID Related Accession (Same CDS sequence) | XM_017596515.1 | |
Accession Version | XM_017596515.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1125bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | tomoregulin-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005108.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCTGT GGGAGTCCCC GCGGCAGTGC AGCAGCTGGA CACTTTGCGA GGGCTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017452004.1 |
CDS | 428..1552 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017596515.1 |
1 | ATGGTGCTGT GGGAGTCCCC GCGGCAGTGC AGCAGCTGGA CACTTTGCGA GGGCTTCTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The TMEFF2 tumor suppressor modulates integrin expression, RhoA activation and migration of prostate cancer cells. |
Refined mapping of blood pressure quantitative trait loci using congenic strains developed from two genetically hypertensive rat models. |
Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo. |
Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer. |