| Gene Symbol | Cngb3 |
| Entrez Gene ID | 500418 |
| Full Name | cyclic nucleotide gated channel beta 3 |
| Synonyms | Cng6,RGD1565364 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
The following Cngb3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cngb3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa10701 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001271238.1 | |
| Accession Version | NM_001271238.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2073bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-07-09 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cyclic nucleotide-gated cation channel beta-3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AABR07047458.1, AABR07047466.1, AABR07047471.1 and AABR07047477.1. On Sep 8, 2012 this sequence version replaced XM_001057513.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMD00052296, SAMD00052297 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTTAAAAT CTCTGACAGT AAAATGCAAC AAAGTGAAGC CCATGGAAGG GAGGACCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001258167.1 |
| CDS | 1..2073 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001271238.1 |
1 | ATGTTAAAAT CTCTGACAGT AAAATGCAAC AAAGTGAAGC CCATGGAAGG GAGGACCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa61348 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017593570.1 | |
| Accession Version | XM_017593570.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | cyclic nucleotide-gated cation channel beta-3 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005104.4) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGTTAAAAT CTCTGACAGT AAAATGCAAC AAAGTGAAGC CCATGGAAGG GAGGACCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017449059.1 |
| CDS | 302..2386 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017593570.1 |
1 | ATGTTAAAAT CTCTGACAGT AAAATGCAAC AAAGTGAAGC CCATGGAAGG GAGGACCGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating. |
Calcium signalling remodelling and disease. |
Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy. |
Achromatopsia: the CNGB3 p.T383fsX mutation results from a founder effect and is responsible for the visual phenotype in the original report of uniparental disomy 14. |
Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1. |
