Enpp3 cDNA ORF clone, Rattus norvegicus(Norway rat)
Gene Symbol | Enpp3 |
Entrez Gene ID | 54410 |
Full Name | ectonucleotide pyrophosphatase/phosphodiesterase 3 |
Synonyms | B10,E-NPP 3,Npp3,PD-Ibeta,RB13-6 |
General protein information |
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Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | alkaline phosphodiesterase I; may be involved in regulation of vascular smooth muscle cell growth [RGD, Feb 2006]. |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_019370.2 | NP_062243.2 | ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |

Arabidopsis thaliana (thale cress) | AT4G29690 | NP_194698.1 |
Canis lupus familiaris (dog) | ENPP3 | XP_005627149.1 |
Mus musculus (house mouse) | Enpp3 | NP_598766.2 |
ENPP3 | XP_001103528.1 | |
Gallus gallus (chicken) | ENPP3 | XP_003641087.1 |
Arabidopsis thaliana (thale cress) | AT4G29700 | NP_194699.1 |
Xenopus tropicalis (tropical clawed frog) | enpp3 | XP_002936359.2 |
Pan troglodytes (chimpanzee) | ENPP3 | XP_518741.2 |
Homo sapiens (human) | ENPP3 | NP_005012.2 |
Bos taurus (cattle) | ENPP3 | NP_001069391.1 |
Rattus norvegicus (Norway rat) | Enpp3 | NP_062243.2 |

Related articles in PubMed
The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells.
Tsai SH, Kinoshita M, Kusu T, Kayama H, Okumura R, Ikeda K, Shimada Y, Takeda A, Yoshikawa S, Obata-Ninomiya K, Kurashima Y, Sato S, Umemoto E, Kiyono H, Karasuyama H, Takeda K
Immunity42(2)279-293(2015 Feb)
Expression of membrane-bound NPP-type ecto-phosphodiesterases in rat podocytes cultured at normal and high glucose concentrations.
Jankowski M, Piwkowska A, Rogacka D, Audzeyenka I, Janaszak-Jasiecka A, Angielski S
Biochemical and biophysical research communications416(1-2)64-9(2011 Dec)
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ecto-nucleotide pyrophosphatase/phosphodiesterase 1 and 3 are expressed on podocytes, but changes in expression of these enzymes are most likely not involved in etiology of insulin resistance in podocytes.
Title: Expression of membrane-bound NPP-type ecto-phosphodiesterases in rat podocytes cultured at normal and high glucose concentrations.
The expression of NPP3 decreased during the aging mainly on cerebellum, hippocampus, and olfactory bulb.
Title: Expression mapping of ectonucleotide pyrophosphatase/phosphodiesterase 1-3 (E-NPP1-3) in different brain structures during rat development.
Lubrol resistance is an intrinsic property of NPP3 but not NPP1, which is acquired early during the biosynthetic process irrespective of its final destination, and depends on positively charged residues in its cytoplasmic tail.
Title: Differential detergent resistance of the apical and basolateral NPPases: relationship with polarized targeting.
The following Enpp3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Enpp3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa04583 | |
Clone ID Related Accession (Same CDS sequence) | NM_019370.2 | |
Accession Version | NM_019370.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2628bp) Protein sequence SNP |
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Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | ectonucleotide pyrophosphatase/phosphodiesterase family member 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC097326.1. On Dec 11, 2007 this sequence version replaced NM_019370.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC097326.1, U78787.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689596, SAMEA2689597 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGATTCCA GGCTAGCTTT AGCCACGGAG GAGCCCATTA AGAAAGACAG CCTGAAGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_062243.2 |
CDS | 57..2684 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGGATTCCA GGCTAGCTTT AGCCACGGAG GAGCCCATTA AGAAAGACAG CCTGAAGAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells. |
![]() |
Expression of membrane-bound NPP-type ecto-phosphodiesterases in rat podocytes cultured at normal and high glucose concentrations. |
![]() |
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). |