| Gene Symbol | Mlh1 |
| Entrez Gene ID | 81685 |
| Full Name | mutL homolog 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome | |
| Summary | may be involved in DNA mismatch repair [RGD, Feb 2006]. |
The following Mlh1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mlh1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa07475 | |
| Clone ID Related Accession (Same CDS sequence) | NM_031053.1 | |
| Accession Version | NM_031053.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2274bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-23 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | DNA mismatch repair protein Mlh1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from U80054.1. On Jan 12, 2005 this sequence version replaced XM_346837.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U80054.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMD00052296, SAMD00052297 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGTCATTTG TAGCAGGAGT TATTCGGCGC CTGGACGAGA CGGTAGTGAA TCGCATAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_112315.1 |
| CDS | 1..2274 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_031053.1 |
1 | ATGTCATTTG TAGCAGGAGT TATTCGGCGC CTGGACGAGA CGGTAGTGAA TCGCATAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa62561 | |
| Clone ID Related Accession (Same CDS sequence) | XM_017595929.1 | |
| Accession Version | XM_017595929.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | DNA mismatch repair protein Mlh1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005107.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGAATGGCT ATATCTCGAA TGCAAACTAC TCAGTGAAGA AGTGCATTTT CCTACTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017451418.1 |
| CDS | 679..2232 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017595929.1 |
1 | ATGAATGGCT ATATCTCGAA TGCAAACTAC TCAGTGAAGA AGTGCATTTT CCTACTCTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein. |
MCM9 Is Required for Mammalian DNA Mismatch Repair. |
Meikin is a conserved regulator of meiosis-I-specific kinetochore function. |
Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites. |
Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair. |
