Gene Symbol | Retnla |
Entrez Gene ID | 81712 |
Full Name | resistin like alpha |
Synonyms | Himf |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | may act as a hormone [RGD, Feb 2006]. |
ORF » Species Summary » Rattus norvegicus » Retnla cDNA ORF clone
Gene Symbol | Retnla |
Entrez Gene ID | 81712 |
Full Name | resistin like alpha |
Synonyms | Himf |
General protein information |
|
Gene Type | protein-coding |
Organism | Rattus norvegicus(Norway rat) |
Genome | |
Summary | may act as a hormone [RGD, Feb 2006]. |
mRNA | Protein | Name |
---|---|---|
NM_053333.1 | NP_445785.1 | resistin-like alpha precursor |
XM_006248283.3 | XP_006248345.1 | resistin-like alpha isoform X1 |
Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension.
Zeng X, Zhu L, Xiao R, Liu B, Sun M, Liu F, Hao Q, Lu Y, Zhang J, Li J, Wang T, Wei X, Hu Q
Hypertension (Dallas, Tex. : 1979)69(5)844-854(2017 05)
Resistin-Like Molecule-? Causes Lung Injury in Rats with Acute Pancreatitis by Activating the PI-3K/Akt-NF-?B Pathway and Promoting Inflammatory Cytokine Release.
Wang WY, Chen Y, Su X, Tang D, Ben QW, Yao WY, Chen P, Yuan YZ
Current molecular medicine16(7)677-687(2016)
FIZZ1 could enhance the angiogenic ability of rat aortic endothelial cells.
Li X, Yang Y, Fang J, Zhang H
International journal of clinical and experimental pathology6(9)1847-53(2013)
[Roles of FIZZ1 and NOTCH1 in asthma].
Luan B, Feng XX, Yang YX, Zhang ZY
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics13(3)219-22(2011 Mar)
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension.
Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Skinner JT, Champion HC, Crow MT, Johns RA
American journal of physiology. Lung cellular and molecular physiology296(4)L582-93(2009 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The binding of HIMF enhanced the activity of extracellular CaSR and mediated hypoxia-evoked proliferation of pulmonary artery smooth cells and the development of pulmonary vascular remodeling and pulmonary hypertension
Title: Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension.
RELMalpha augments inflammatory activity by increasing inflammatory cytokine release.
Title: Resistin-Like Molecule-? Causes Lung Injury in Rats with Acute Pancreatitis by Activating the PI-3K/Akt-NF-?B Pathway and Promoting Inflammatory Cytokine Release.
FIZZ1 could enhance angiogenesis of rat aortic endothelial cells by up-regulating Gng8 and Atg9a.
Title: FIZZ1 could enhance the angiogenic ability of rat aortic endothelial cells.
FIZZl and NOTCH1 may induce an increase in a-SMA expression. FIZZl and NOTCH1 play a critical role in the process of airway remodeling.
Title: [Roles of FIZZ1 and NOTCH1 in asthma].
HIMF represents a critical cytokine-like growth factor in the development of pulmonary hypertension.
Title: Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension.
The following Retnla gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Retnla cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ORa13027 | |
Clone ID Related Accession (Same CDS sequence) | NM_053333.1 , XM_006248283.3 | |
Accession Version | NM_053333.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | resistin-like alpha precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF323085.1. ##Evidence-Data-START## Transcript exon combination :: AF323085.1, AW917630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689599 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGACTG CAACCTGTTC CCTTCTCATC TGCGTCTTCC TTCTCCAGCT GATGGTCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_445785.1 |
CDS | 30..365 |
Translation |
Target ORF information:
Target ORF information:
|
NM_053333.1 |
1 | ATGAAGACTG CAACCTGTTC CCTTCTCATC TGCGTCTTCC TTCTCCAGCT GATGGTCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | ORa13027 | |
Clone ID Related Accession (Same CDS sequence) | NM_053333.1 , XM_006248283.3 | |
Accession Version | XM_006248283.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 336bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-07-25 | |
Organism | Rattus norvegicus(Norway rat) | |
Product | resistin-like alpha isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005110.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_006248283.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGACTG CAACCTGTTC CCTTCTCATC TGCGTCTTCC TTCTCCAGCT GATGGTCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006248345.1 |
CDS | 135..470 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006248283.3 |
1 | ATGAAGACTG CAACCTGTTC CCTTCTCATC TGCGTCTTCC TTCTCCAGCT GATGGTCCCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Hypoxia-Induced Mitogenic Factor Acts as a Nonclassical Ligand of Calcium-Sensing Receptor, Therapeutically Exploitable for Intermittent Hypoxia-Induced Pulmonary Hypertension. |
Resistin-Like Molecule-? Causes Lung Injury in Rats with Acute Pancreatitis by Activating the PI-3K/Akt-NF-?B Pathway and Promoting Inflammatory Cytokine Release. |
FIZZ1 could enhance the angiogenic ability of rat aortic endothelial cells. |
[Roles of FIZZ1 and NOTCH1 in asthma]. |
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMalpha) induces the vascular and hemodynamic changes of pulmonary hypertension. |