Gene Symbol | calr |
Entrez Gene ID | 325317 |
Full Name | calreticulin |
Synonyms | calrl2,fc66d10,wu:fc66d10,wu:fj50c03,zgc:66153 |
General protein information |
|
Gene Type | protein-coding |
Organism | Danio rerio(zebrafish) |
ORF » Species Summary » Danio rerio » calr cDNA ORF clone
Gene Symbol | calr |
Entrez Gene ID | 325317 |
Full Name | calreticulin |
Synonyms | calrl2,fc66d10,wu:fc66d10,wu:fj50c03,zgc:66153 |
General protein information |
|
Gene Type | protein-coding |
Organism | Danio rerio(zebrafish) |
mRNA | Protein | Name |
---|---|---|
NM_199713.2 | NP_956007.2 | calreticulin precursor |
Bos taurus (cattle) | CALR | NP_776425.1 |
Danio rerio (zebrafish) | calrl2 | NP_956007.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP004212 | XP_313116.1 |
Arabidopsis thaliana (thale cress) | CRT1b | NP_172392.1 |
Mus musculus (house mouse) | Calr | NP_031617.1 |
Rattus norvegicus (Norway rat) | Calr | NP_071794.1 |
Gallus gallus (chicken) | CALR3 | XP_418262.3 |
Arabidopsis thaliana (thale cress) | CRT1a | NP_176030.1 |
Homo sapiens (human) | CALR | NP_004334.1 |
Oryza sativa (rice) | Os03g0832200 | NP_001051799.1 |
Pan troglodytes (chimpanzee) | CALR | XP_003316194.1 |
Canis lupus familiaris (dog) | CALR | XP_867310.2 |
Caenorhabditis elegans (roundworm) | crt-1 | NP_504575.1 |
Oryza sativa (rice) | Os07g0246200 | NP_001059283.1 |
Xenopus tropicalis (tropical clawed frog) | calr | NP_001001253.1 |
CALR | XP_001110217.1 | |
Drosophila melanogaster (fruit fly) | Crc | NP_001262430.1 |
Activation of the
Sun Y, Wang Q, Fang Y, Wu C, Lu G, Chen Z
Disease models & mechanisms10(10)1217-1227(2017 Oct)
Evolution of complexity in the zebrafish synapse proteome.
Bay?s ?, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG
Nature communications814613(2017 Mar)
Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish.
Lim KH, Chang YC, Chiang YH, Lin HC, Chang CY, Lin CS, Huang L, Wang WT, Gon-Shen Chen C, Chou WC, Kuo YY
Blood cancer journal6(10)e481(2016 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These findings showed that mutant CALR activates jak-stat signaling through an mpl-dependent mechanism to mediate pathogenic thrombopoiesis in zebrafish, and illustrated that the signaling machinery related to mutant CALR tumorigenesis are conserved between human and zebrafish.
Title: Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish.
The following calr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the calr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | ODa39843 | |
Clone ID Related Accession (Same CDS sequence) | NM_199713.2 | |
Accession Version | NM_199713.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-05 | |
Organism | Danio rerio(zebrafish) | |
Product | calreticulin precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CU467861.7 and EH505639.1. On Jun 19, 2015 this sequence version replaced NM_199713.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GFIL01002922.1, BC057469.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476737 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACTGCGT TATCCCTACT GTTTATGGCC GTGTCCGTCG CTTTAATAAC CGCAGAGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_956007.2 |
CDS | 170..1423 |
Translation |
Target ORF information:
Target ORF information:
|
NM_199713.2 |
1 | ATGACTGCGT TATCCCTACT GTTTATGGCC GTGTCCGTCG CTTTAATAAC CGCAGAGTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Activation of the |
Evolution of complexity in the zebrafish synapse proteome. |
Expression of CALR mutants causes mpl-dependent thrombocytosis in zebrafish. |