Gene Symbol | FAM173B |
Entrez Gene ID | 134145 |
Full Name | family with sequence similarity 173 member B |
Synonyms | JS-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » FAM173B cDNA ORF clone
Gene Symbol | FAM173B |
Entrez Gene ID | 134145 |
Full Name | family with sequence similarity 173 member B |
Synonyms | JS-2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001258388.1 | NP_001245317.1 | ATP synthase subunit C lysine N-methyltransferase isoform 2 |
NM_001258389.1 | NP_001245318.1 | ATP synthase subunit C lysine N-methyltransferase isoform 3 |
XM_011513964.2 | XP_011512266.1 | ATP synthase subunit C lysine N-methyltransferase isoform X1 |
NM_199133.4 | NP_954584.2 | ATP synthase subunit C lysine N-methyltransferase isoform 1 |
XM_011513964.1 | XP_011512266.1 | protein FAM173B isoform X1 |
NM_199133.3 | NP_954584.2 | protein FAM173B isoform 1 |
Bos taurus (cattle) | FAM173B | XP_002696485.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002286 | XP_307892.4 |
Rattus norvegicus (Norway rat) | Fam173b | NP_001102648.1 |
Gallus gallus (chicken) | FAM173B | XP_426055.4 |
Drosophila melanogaster (fruit fly) | CG3337 | NP_650957.1 |
Homo sapiens (human) | FAM173B | NP_954584.2 |
Mus musculus (house mouse) | Fam173b | NP_080822.1 |
Pan troglodytes (chimpanzee) | FAM173B | NP_001230024.1 |
Canis lupus familiaris (dog) | FAM173B | XP_535794.3 |
Danio rerio (zebrafish) | fam173b | NP_001007392.1 |
Caenorhabditis elegans (roundworm) | CELE_Y39A1A.21 | NP_001022840.1 |
Xenopus tropicalis (tropical clawed frog) | fam173b | NP_001016023.2 |
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region.
Peters MJ, Broer L, Willemen HL, Eiriksdottir G, Hocking LJ, Holliday KL, Horan MA, Meulenbelt I, Neogi T, Popham M, Schmidt CO, Soni A, Valdes AM, Amin N, Dennison EM, Eijkelkamp N, Harris TB, Hart DJ, Hofman A, Huygen FJ, Jameson KA, Jones GT, Launer LJ, Kerkhof HJ, de Kruijf M, McBeth J, Kloppenburg M, Ollier WE, Oostra B, Payton A, Rivadeneira F, Smith BH, Smith AV, Stolk L, Teumer A, Thomson W, Uitterlinden AG, Wang K, van Wingerden SH, Arden NK, Cooper C, Felson D, Gudnason V, Macfarlane GJ, Pendleton N, Slagboom PE, Spector TD, V?lzke H, Kavelaars A, van Duijn CM, Williams FM, van Meurs JB
Annals of the rheumatic diseases72(3)427-36(2013 Mar)
Altered JS-2 expression in colorectal cancers and its clinical pathological relevance.
Lam AK, Gopalan V, Nassiri MR, Kasim K, Dissanayake J, Tang JC, Smith RA
Molecular oncology5(5)475-81(2011 Oct)
The transcriptome of human CD34+ hematopoietic stem-progenitor cells.
Kim YC, Wu Q, Chen J, Xuan Z, Jung YC, Zhang MQ, Rowley JD, Wang SM
Proceedings of the National Academy of Sciences of the United States of America106(20)8278-83(2009 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Genetic alteration of JS-2 was found to be related to location, pathological subtypes and staging of colorectal cancer.
Title: Altered JS-2 expression in colorectal cancers and its clinical pathological relevance.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
The following FAM173B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the FAM173B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu00344 | |
Clone ID Related Accession (Same CDS sequence) | NM_001258388.1 | |
Accession Version | NM_001258388.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 651bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Homo sapiens(human) | |
Product | ATP synthase subunit C lysine N-methyltransferase isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GD160552.1, DW420473.1, AK302012.1 and AC034229.4. Transcript Variant: This variant (2) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.32000.1, SRR1163658.349520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001245317.1 |
CDS | 37..687 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001258388.1 |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00358 | |
Clone ID Related Accession (Same CDS sequence) | NM_199133.4 , NM_199133.3 | |
Accession Version | NM_199133.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-03 | |
Organism | Homo sapiens(human) | |
Product | ATP synthase subunit C lysine N-methyltransferase isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GD160552.1, AK300042.1 and AC034229.4. On Nov 22, 2018 this sequence version replaced NM_199133.3. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.92490.1, SRR1660809.104696.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000511437.6/ ENSP00000422338.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_954584.2 |
CDS | 16..717 |
Translation |
Target ORF information:
Target ORF information:
|
NM_199133.4 |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00358 | |
Clone ID Related Accession (Same CDS sequence) | NM_199133.4 , NM_199133.3 | |
Accession Version | NM_199133.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 702bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | protein FAM173B isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GD160552.1, AK300042.1 and AC034229.4. On May 1, 2012 this sequence version replaced NM_199133.2. Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.104696.1, SRR1803613.100737.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2155371 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_954584.2 |
CDS | 37..738 |
Translation |
Target ORF information:
Target ORF information:
|
NM_199133.3 |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00763 | |
Clone ID Related Accession (Same CDS sequence) | NM_001258389.1 | |
Accession Version | NM_001258389.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 477bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Homo sapiens(human) | |
Product | ATP synthase subunit C lysine N-methyltransferase isoform 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from GD160552.1, DA523490.1 and AC034229.4. Transcript Variant: This variant (3) uses an alternate splice site in the coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.83094.1, SRR1660805.94818.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2155371 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001245318.1 |
CDS | 37..513 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001258389.1 |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu75732 | |
Clone ID Related Accession (Same CDS sequence) | XM_011513964.2 , XM_011513964.1 | |
Accession Version | XM_011513964.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | ATP synthase subunit C lysine N-methyltransferase isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011513964.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011512266.1 |
CDS | 16..552 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011513964.2 |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu75732 | |
Clone ID Related Accession (Same CDS sequence) | XM_011513964.2 , XM_011513964.1 | |
Accession Version | XM_011513964.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | protein FAM173B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000005.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011512266.1 |
CDS | 24..560 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011513964.1 |
1 | ATGGAGGGAG GAGGAGGTAT ACCCCTAGAA ACACTTAAAG AAGAAAGTCA GTCAAGACAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome-wide association study meta-analysis of chronic widespread pain: evidence for involvement of the 5p15.2 region. |
Altered JS-2 expression in colorectal cancers and its clinical pathological relevance. |
The transcriptome of human CD34+ hematopoietic stem-progenitor cells. |