Gene Symbol | COPG1 |
Entrez Gene ID | 22820 |
Full Name | coatomer protein complex subunit gamma 1 |
Synonyms | COPG |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » COPG1 cDNA ORF clone
Gene Symbol | COPG1 |
Entrez Gene ID | 22820 |
Full Name | coatomer protein complex subunit gamma 1 |
Synonyms | COPG |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_016128.4 | NP_057212.1 | coatomer subunit gamma-1 |
NM_016128.3 | NP_057212.1 | coatomer subunit gamma-1 |
XM_011512549.2 | XP_011510851.1 | coatomer subunit gamma-1 isoform X1 |
Pan troglodytes (chimpanzee) | COPG1 | XP_001141317.1 |
LOC705387 | XP_002798755.1 | |
Bos taurus (cattle) | COPG1 | NP_001032904.1 |
Gallus gallus (chicken) | COPG | NP_001025768.1 |
Canis lupus familiaris (dog) | COPG1 | XP_533723.2 |
Homo sapiens (human) | COPG1 | NP_057212.1 |
Mus musculus (house mouse) | Copg1 | NP_059505.1 |
Rattus norvegicus (Norway rat) | Copg1 | NP_001026992.1 |
Xenopus tropicalis (tropical clawed frog) | copg1 | NP_989174.1 |
?-COPI mediates the retention of kAE1 G701D protein in Golgi apparatus - a mechanistic explanation of distal renal tubular acidosis associated with the G701D mutation.
Duangtum N, Junking M, Phadngam S, Sawasdee N, Castiglioni A, Charngkaew K, Limjindaporn T, Isidoro C, Yenchitsomanus PT
The Biochemical journal474(15)2573-2584(2017 07)
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.
Taipale M, Tucker G, Peng J, Krykbaeva I, Lin ZY, Larsen B, Choi H, Berger B, Gingras AC, Lindquist S
Cell158(2)434-448(2014 Jul)
Golgi-situated endoplasmic reticulum ?-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with ?-COP.
Pan S, Cheng X, Sifers RN
Molecular biology of the cell24(8)1111-21(2013 Apr)
Association study of 182 candidate genes in anorexia nervosa.
Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics153B(5)1070-80(2010 Jul)
A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor.
Deng Y, Golinelli-Cohen MP, Smirnova E, Jackson CL
EMBO reports10(1)58-64(2009 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These data unveil the molecular mechanism of Golgi retention of kAE1 G701D and suggest that disruption of the COPI-kAE1 G701D interaction could be a therapeutic strategy to treat distal renal tubular acidosis caused by this mutant.
Title: ?-COPI mediates the retention of kAE1 G701D protein in Golgi apparatus - a mechanistic explanation of distal renal tubular acidosis associated with the G701D mutation.
ERManI and gamma-COP contribute to a golgi-based quality control module that facilitates the retrieval of captured ERAD substrates back to the endoplasmic reticulum.
Title: Golgi-situated endoplasmic reticulum ?-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with ?-COP.
Observational study of gene-disease association. (HuGE Navigator)
Title: Association study of 182 candidate genes in anorexia nervosa.
Results describe the structure of the appendage domain of gamma-COP and show that it has a similar overall fold as the alpha-appendage of AP2.
Title: Gamma-COP appendage domain - structure and function.
The D1 receptor associates with the gamma-subunit of the COPI coatomer complex. Association between the coatomer complex and hydrophobic residues within the proximal C-terminus of the D1 receptor may serve an important role in receptor transport.
Title: Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus.
The following COPG1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COPG1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu29546 | |
Clone ID Related Accession (Same CDS sequence) | NM_016128.4 , NM_016128.3 | |
Accession Version | NM_016128.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2625bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-28 | |
Organism | Homo sapiens(human) | |
Product | coatomer subunit gamma-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC137695.3, BU521557.1, AB047846.1 and AK025147.1. On Nov 22, 2018 this sequence version replaced NM_016128.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291693.1, SRR1803611.232327.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000314797.10/ ENSP00000325002.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGTTGAAGA AATTCGACAA GAAGGATGAG GAGTCAGGTG GAGGCTCCAA CCCATTCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_057212.1 |
CDS | 105..2729 |
Translation |
Target ORF information:
Target ORF information:
|
NM_016128.4 |
1 | ATGTTGAAGA AATTCGACAA GAAGGATGAG GAGTCAGGTG GAGGCTCCAA CCCATTCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu29546 | |
Clone ID Related Accession (Same CDS sequence) | NM_016128.4 , NM_016128.3 | |
Accession Version | NM_016128.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2625bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Homo sapiens(human) | |
Product | coatomer subunit gamma-1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU521557.1, AB047846.1 and AK025147.1. On Sep 25, 2003 this sequence version replaced NM_016128.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF100756.1, AK291693.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTTGAAGA AATTCGACAA GAAGGATGAG GAGTCAGGTG GAGGCTCCAA CCCATTCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_057212.1 |
CDS | 101..2725 |
Translation |
Target ORF information:
Target ORF information:
|
NM_016128.3 |
1 | ATGTTGAAGA AATTCGACAA GAAGGATGAG GAGTCAGGTG GAGGCTCCAA CCCATTCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu64956 | |
Clone ID Related Accession (Same CDS sequence) | XM_011512549.2 | |
Accession Version | XM_011512549.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1611bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | coatomer subunit gamma-1 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011512549.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTGAAGA AATTCGACAA GAAGGATGAG GAGTCAGGTG GAGGCTCCAA CCCATTCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011510851.1 |
CDS | 136..1746 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011512549.2 |
1 | ATGTTGAAGA AATTCGACAA GAAGGATGAG GAGTCAGGTG GAGGCTCCAA CCCATTCCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
?-COPI mediates the retention of kAE1 G701D protein in Golgi apparatus - a mechanistic explanation of distal renal tubular acidosis associated with the G701D mutation. |
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways. |
Golgi-situated endoplasmic reticulum ?-1, 2-mannosidase contributes to the retrieval of ERAD substrates through a direct interaction with ?-COP. |
Association study of 182 candidate genes in anorexia nervosa. |
A COPI coat subunit interacts directly with an early-Golgi localized Arf exchange factor. |