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TARDBP cDNA ORF clone, Homo sapiens(Human)

Gene Symbol TARDBP
Entrez Gene ID 23435
Full Name TAR DNA binding protein
Synonyms ALS10,TDP-43
General protein information
Preferred Names

TAR DNA binding protein

Names

TAR DNA-binding protein 43
TAR DNA-binding protein-43

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

1

1p36.22

Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008].
Disorder MIM:

605078

Disorder Html: Amyotrophic lateral sclerosis 10, with or without FTD, 612069 (3);

mRNA and Protein(s)

mRNA Protein Name
XM_017000864.1 XP_016856353.1 TAR DNA-binding protein 43 isoform X1
XM_017000865.1 XP_016856354.1 TAR DNA-binding protein 43 isoform X1
XM_017000868.1 XP_016856357.1 TAR DNA-binding protein 43 isoform X1
NM_007375.3 NP_031401.1 TAR DNA-binding protein 43
XM_017000863.1 XP_016856352.1 TAR DNA-binding protein 43 isoform X1
XM_017000866.1 XP_016856355.1 TAR DNA-binding protein 43 isoform X1
XM_017000867.1 XP_016856356.1 TAR DNA-binding protein 43 isoform X1



Homo sapiens (human) TARDBP NP_031401.1
Bos taurus (cattle) TARDBP NP_001039950.2
Macaca mulatta (rhesus monkey) TARDBP XP_001102660.1
Pan troglodytes (chimpanzee) TARDBP XP_514380.2
Danio rerio (zebrafish) tardbp NP_958884.1
Xenopus tropicalis (tropical clawed frog) tardbp NP_989054.2
Canis lupus familiaris (dog) TARDBP XP_005618063.1
Mus musculus (house mouse) Tardbp NP_663531.1
Gallus gallus (chicken) TARDBP NP_001026049.1


Related articles in PubMed

TAR DNA-binding protein 43 inhibits inflammatory response and protects chondrocyte function by modulating RACK1 expression in osteoarthritis.
Huang Y, Huang Q, Su H, Mai X, Feng E, Cao Z, Zeng X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie85362-371(2017 Jan)

Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.
Mashiko T, Sakashita E, Kasashima K, Tominaga K, Kuroiwa K, Nozaki Y, Matsuura T, Hamamoto T, Endo H
The Journal of biological chemistry291(29)14996-5007(2016 07)

Inter-domain interactions of TDP-43 as decoded by NMR.
Wei Y, Lim L, Wang L, Song J
Biochemical and biophysical research communications473(2)614-9(2016 Apr)

USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock.
Hirano A, Nakagawa T, Yoshitane H, Oyama M, Kozuka-Hata H, Lanjakornsiripan D, Fukada Y
PloS one11(4)e0154263(2016)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These results suggest that Perry syndrome may be distinctive type of TDP-43 proteinopathy.
Title: Perry Syndrome: A Distinctive Type of TDP-43 Proteinopathy.

TDP-43 pathologic burden in amyotrophic lateral sclerosis is associated with cognitive impairment and c9orf72-associated amyotrophic lateral sclerosis , but not duration of disease or rate of progression
Title: Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis.

results from this study suggest that TDP-43 represents a translational repressor not only for specific mRNAs but for overall translation and that its binding to polyribosomes through RACK1 may promote, under conditions inducingAmyotrophic Lateral Sclerosis pathogenesis, the formation of cytoplasmic inclusions.
Title: Increased cytoplasmic TDP-43 reduces global protein synthesis by interacting with RACK1 on polyribosomes.

Data suggest that transitions of TDP-43 among soluble, droplet, and aggregate phases are involved in pathological aggregation; TDP-43 prion-like domain appears to wobble at a cusp of the protein folding energy landscape where any number of factors can tip the balance and trigger the conversion from its native function to its pathological one. [REVIEW]
Title: Phase to Phase with TDP-43.

Taken together, inhibition of nuclear import of TDP-43 by cytoplasmic poly-GA inclusions causally links the two main aggregating proteins in C9orf72 amyotrophic lateral sclerosis /lobar degeneration pathogenesis.
Title: Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.

The following TARDBP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TARDBP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Online Only Promotion

Up to 50% OFF! Starting
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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu19093 NM_007375.3
Latest version!
Homo sapiens TAR DNA binding protein (TARDBP), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu19093 XM_017000866.1
Latest version!
Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu19093 XM_017000867.1
Latest version!
Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X5, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu19093 XM_017000864.1
Latest version!
Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu19093 XM_017000863.1
Latest version!
Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu19093 XM_017000865.1
Latest version!
Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu19093 XM_017000868.1
Latest version!
Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X6, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu19093
Clone ID Related Accession (Same CDS sequence) XM_017000864.1 , XM_017000865.1 , XM_017000868.1 , NM_007375.3 , XM_017000863.1 , XM_017000866.1 , XM_017000867.1
Accession Version NM_007375.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1245bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-26
Organism Homo sapiens(Human)
Product TAR DNA-binding protein 43
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI464234.1, CD703666.1, BC001487.2, AL050265.1, AL045296.1, BC059955.1, AF311304.1 and BM716882.1. This sequence is a reference standard in the RefSeqGene project. On or before Feb 23, 2004 this sequence version replaced NM_031214.1, NM_007375.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.131063.1, SRR1803611.43235.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
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121
181
241
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361
421
481
541
601
661
721
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841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_031401.1
CDS135..1379
Misc Feature(1)129..131
Exon (1)1..122
Exon (2)123..372
Translation

Target ORF information:

RefSeq Version NM_007375.3
Organism Homo sapiens(Human)
Definition Homo sapiens TAR DNA binding protein (TARDBP), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_007375.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19093
Clone ID Related Accession (Same CDS sequence) XM_017000864.1 , XM_017000865.1 , XM_017000868.1 , NM_007375.3 , XM_017000863.1 , XM_017000866.1 , XM_017000867.1
Accession Version XM_017000864.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1245bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product TAR DNA-binding protein 43 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016856353.1
CDS123..1367
Translation

Target ORF information:

RefSeq Version XM_017000864.1
Organism Homo sapiens(Human)
Definition Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017000864.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19093
Clone ID Related Accession (Same CDS sequence) XM_017000864.1 , XM_017000865.1 , XM_017000868.1 , NM_007375.3 , XM_017000863.1 , XM_017000866.1 , XM_017000867.1
Accession Version XM_017000865.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1245bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product TAR DNA-binding protein 43 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016856354.1
CDS123..1367
Translation

Target ORF information:

RefSeq Version XM_017000865.1
Organism Homo sapiens(Human)
Definition Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017000865.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19093
Clone ID Related Accession (Same CDS sequence) XM_017000864.1 , XM_017000865.1 , XM_017000868.1 , NM_007375.3 , XM_017000863.1 , XM_017000866.1 , XM_017000867.1
Accession Version XM_017000868.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1245bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product TAR DNA-binding protein 43 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016856357.1
CDS123..1367
Translation

Target ORF information:

RefSeq Version XM_017000868.1
Organism Homo sapiens(Human)
Definition Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X6, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017000868.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19093
Clone ID Related Accession (Same CDS sequence) XM_017000864.1 , XM_017000865.1 , XM_017000868.1 , NM_007375.3 , XM_017000863.1 , XM_017000866.1 , XM_017000867.1
Accession Version XM_017000863.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1245bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product TAR DNA-binding protein 43 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016856352.1
CDS123..1367
Translation

Target ORF information:

RefSeq Version XM_017000863.1
Organism Homo sapiens(Human)
Definition Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017000863.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19093
Clone ID Related Accession (Same CDS sequence) XM_017000864.1 , XM_017000865.1 , XM_017000868.1 , NM_007375.3 , XM_017000863.1 , XM_017000866.1 , XM_017000867.1
Accession Version XM_017000866.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1245bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product TAR DNA-binding protein 43 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016856355.1
CDS123..1367
Translation

Target ORF information:

RefSeq Version XM_017000866.1
Organism Homo sapiens(Human)
Definition Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017000866.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu19093
Clone ID Related Accession (Same CDS sequence) XM_017000864.1 , XM_017000865.1 , XM_017000868.1 , NM_007375.3 , XM_017000863.1 , XM_017000866.1 , XM_017000867.1
Accession Version XM_017000867.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1245bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product TAR DNA-binding protein 43 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016856356.1
CDS123..1367
Translation

Target ORF information:

RefSeq Version XM_017000867.1
Organism Homo sapiens(Human)
Definition Homo sapiens TAR DNA binding protein (TARDBP), transcript variant X5, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_017000867.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGTCTGAAT ATATTCGGGT AACCGAAGAT GAGAACGATG AGCCCATTGA AATACCATCG 
GAAGACGATG GGACGGTGCT GCTCTCCACG GTTACAGCCC AGTTTCCAGG GGCGTGTGGG
CTTCGCTACA GGAATCCAGT GTCTCAGTGT ATGAGAGGTG TCCGGCTGGT AGAAGGAATT
CTGCATGCCC CAGATGCTGG CTGGGGAAAT CTGGTGTATG TTGTCAACTA TCCAAAAGAT
AACAAAAGAA AAATGGATGA GACAGATGCT TCATCAGCAG TGAAAGTGAA AAGAGCAGTC
CAGAAAACAT CCGATTTAAT AGTGTTGGGT CTCCCATGGA AAACAACCGA ACAGGACCTG
AAAGAGTATT TTAGTACCTT TGGAGAAGTT CTTATGGTGC AGGTCAAGAA AGATCTTAAG
ACTGGTCATT CAAAGGGGTT TGGCTTTGTT CGTTTTACGG AATATGAAAC ACAAGTGAAA
GTAATGTCAC AGCGACATAT GATAGATGGA CGATGGTGTG ACTGCAAACT TCCTAATTCT
AAGCAAAGCC AAGATGAGCC TTTGAGAAGC AGAAAAGTGT TTGTGGGGCG CTGTACAGAG
GACATGACTG AGGATGAGCT GCGGGAGTTC TTCTCTCAGT ACGGGGATGT GATGGATGTC
TTCATCCCCA AGCCATTCAG GGCCTTTGCC TTTGTTACAT TTGCAGATGA TCAGATTGCG
CAGTCTCTTT GTGGAGAGGA CTTGATCATT AAAGGAATCA GCGTTCATAT ATCCAATGCC
GAACCTAAGC ACAATAGCAA TAGACAGTTA GAAAGAAGTG GAAGATTTGG TGGTAATCCA
GGTGGCTTTG GGAATCAGGG TGGATTTGGT AATAGCAGAG GGGGTGGAGC TGGTTTGGGA
AACAATCAAG GTAGTAATAT GGGTGGTGGG ATGAACTTTG GTGCGTTCAG CATTAATCCA
GCCATGATGG CTGCCGCCCA GGCAGCACTA CAGAGCAGTT GGGGTATGAT GGGCATGTTA
GCCAGCCAGC AGAACCAGTC AGGCCCATCG GGTAATAACC AAAACCAAGG CAACATGCAG
AGGGAGCCAA ACCAGGCCTT CGGTTCTGGA AATAACTCTT ATAGTGGCTC TAATTCTGGT
GCAGCAATTG GTTGGGGATC AGCATCCAAT GCAGGGTCGG GCAGTGGTTT TAATGGAGGC
TTTGGCTCAA GCATGGATTC TAAGTCTTCT GGCTGGGGAA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

TAR DNA-binding protein 43 inhibits inflammatory response and protects chondrocyte function by modulating RACK1 expression in osteoarthritis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie85362-371(2017 Jan)
Huang Y,Huang Q,Su H,Mai X,Feng E,Cao Z,Zeng X


book

Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.
The Journal of biological chemistry291(29)14996-5007(2016 07)
Mashiko T,Sakashita E,Kasashima K,Tominaga K,Kuroiwa K,Nozaki Y,Matsuura T,Hamamoto T,Endo H


book

Inter-domain interactions of TDP-43 as decoded by NMR.
Biochemical and biophysical research communications473(2)614-9(2016 Apr)
Wei Y,Lim L,Wang L,Song J


book

USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock.
PloS one11(4)e0154263(2016)
Hirano A,Nakagawa T,Yoshitane H,Oyama M,Kozuka-Hata H,Lanjakornsiripan D,Fukada Y


 
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