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MSH6 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol MSH6
Entrez Gene ID 2956
Full Name mutS homolog 6
Synonyms GTBP,GTMBP,HNPCC5,HSAP,p160
General protein information
Preferred Names

mutS homolog 6

Names

DNA mismatch repair protein Msh6
G/T mismatch-binding protein
mutS protein homolog 6
mutS-alpha 160 kDa subunit
sperm-associated protein

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

2

2p16.3

Summary This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013].
Disorder MIM:

600678

Disorder Html: Colorectal cancer, hereditary nonpolyposis, type 5 (3); Endometrial

mRNA and Protein(s)

mRNA Protein Name
XM_011532798.1 XP_011531100.1 DNA mismatch repair protein Msh6 isoform X1
XM_011532799.1 XP_011531101.1 DNA mismatch repair protein Msh6 isoform X2
NM_001281493.1 NP_001268422.1 DNA mismatch repair protein Msh6 isoform 3
NM_001281492.1 NP_001268421.1 DNA mismatch repair protein Msh6 isoform 2
NM_001281494.1 NP_001268423.1 DNA mismatch repair protein Msh6 isoform 3
NM_000179.2 NP_000170.1 DNA mismatch repair protein Msh6 isoform 1



Danio rerio (zebrafish) msh6 NP_878280.1
Drosophila melanogaster (fruit fly) Msh6 NP_648755.1
Caenorhabditis elegans (roundworm) msh-6 NP_491163.1
Saccharomyces cerevisiae (baker's yeast) MSH6 NP_010382.3
Kluyveromyces lactis KLLA0C17732g XP_452992.1
Xenopus tropicalis (tropical clawed frog) msh6 XP_002935421.2
Pan troglodytes (chimpanzee) MSH6 XP_003309101.1
Mus musculus (house mouse) Msh6 NP_034960.1
Eremothecium gossypii AGOS_AGR116W NP_986782.2
Canis lupus familiaris (dog) MSH6 XP_531814.2
Gallus gallus (chicken) MSH6 XP_419359.3
Schizosaccharomyces pombe (fission yeast) msh6 NP_588344.1
Magnaporthe oryzae (rice blast fungus) MGG_00704 XP_003718302.1
Homo sapiens (human) MSH6 NP_000170.1
Bos taurus (cattle) MSH6 NP_001179666.1
Rattus norvegicus (Norway rat) LOC100360342 XP_006239796.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP003190 XP_312887.5
Neurospora crassa NCU08135 XP_959678.2
Arabidopsis thaliana (thale cress) MSH6 NP_192116.1
Macaca mulatta (rhesus monkey) MSH6 XP_001113749.1


Related articles in PubMed

Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer.
Ghanipour L, Jirström K, Sundström M, Glimelius B, Birgisson H
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology43(2)311-321(2017 Feb)

WT1, MSH6, GATA5 and PAX5 as epigenetic oral squamous cell carcinoma biomarkers - a short report.
Ribeiro IP, Caramelo F, Marques F, Domingues A, Mesquita M, Barroso L, Prazeres H, Julião MJ, Baptista IP, Ferreira A, Melo JB, Carreira IM
Cellular oncology (Dordrecht)39(6)573-582(2016 Dec)

Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population.
Lagerstedt-Robinson K, Rohlin A, Aravidis C, Melin B, Nordling M, Stenmark-Askmalm M, Lindblom A, Nilbert M
Oncology reports36(5)2823-2835(2016 Nov)

HMSH2 and HMSH6 gene expression profiles in colorectal adenocarcinoma in patients up to 50 years of age.
Germini D, Gehrke F, Lira D, Alves B, Azzalis L, Perez M, Fonseca F, Waisberg J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie83602-606(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

High MSH6 expression is associated with the development of genetic instability and is linked to tumor aggressiveness and early PSA recurrence in prostate cancer.
Title: Up-regulation of mismatch repair genes MSH6, PMS2 and MLH1 parallels development of genetic instability and is linked to tumor aggressiveness and early PSA recurrence in prostate cancer.

we identified gene promoter methylation signatures (WT1, MSH6, GATA5 and PAX5) that are strongly correlated to, and can have a predictive value for the clinical outcome of oral squamous cell carcinoma patients
Title: WT1, MSH6, GATA5 and PAX5 as epigenetic oral squamous cell carcinoma biomarkers - a short report.

human Pol alpha interacts with MSH2-MSH6 complex
Title: Human DNA polymerase α interacts with mismatch repair proteins MSH2 and MSH6.

A total of 201 unique disease-predisposing mismatch repair gene mutations were identified in 369 Lynch syndrome families. These mutations affected MLH1 in 40%, MSH2 in 36%, MSH6 in 18% and PMS2 in 6% of the families
Title: Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population.

There is a positive correlation between the expressions of hMSH2 and hMSH6 between males (RHO=0.673 and p=0.001) and females with colorectal adenocarcinoma.
Title: HMSH2 and HMSH6 gene expression profiles in colorectal adenocarcinoma in patients up to 50 years of age.

The following MSH6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MSH6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu22411 NM_001281493.1
Latest version!
Homo sapiens mutS homolog 6 (MSH6), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 $559.30
$799.00
OHu22411 NM_001281494.1
Latest version!
Homo sapiens mutS homolog 6 (MSH6), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 16 $559.30
$799.00
OHu27543 NM_001281492.1
Latest version!
Homo sapiens mutS homolog 6 (MSH6), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 $643.30
$919.00
OHu35371 XM_011532799.1
Latest version!
Homo sapiens mutS homolog 6 (MSH6), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 $643.30
$919.00
OHu58146 XM_011532798.1
Latest version!
Homo sapiens mutS homolog 6 (MSH6), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 $643.30
$919.00
OHu25314 NM_000179.2
Latest version!
Homo sapiens mutS homolog 6 (MSH6), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 25 $69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu22411
Clone ID Related Accession (Same CDS sequence) NM_001281493.1 , NM_001281494.1
Accession Version NM_001281493.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3177bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product DNA mismatch repair protein Msh6 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC071594.1 and AC006509.15. Transcript Variant: This variant (3) lacks an alternate in-frame exon and initiates translation at a downstream start codon compared to variant 1. The resulting protein (isoform 3) is shorter and has a distinct N-terminus compared to isoform 1. Variants 3 and 4 encode the same protein (isoform 3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC071594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGTGACTG GAAATGGCTC TCTTAAAAGG AAAAGCTCTA GGAAGGAAAC GCCCTCAGCC 
ACCAAACAAG CAACTAGCAT TTCATCAGAA ACCAAGAATA CTTTGAGAGC TTTCTCTGCC
CCTCAAAATT CTGAATCCCA AGCCCACGTT AGTGGAGGTG GTGATGACAG TAGTCGCCCT
ACTGTTTGGT ATCATGAAAC TTTAGAATGG CTTAAGGAGG AAAAGAGAAG AGATGAGCAC
AGGAGGAGGC CTGATCACCC CGATTTTGAT GCATCTACAC TCTATGTGCC TGAGGATTTC
CTCAATTCTT GTACTCCTGG GATGAGGAAG TGGTGGCAGA TTAAGTCTCA GAACTTTGAT
CTTGTCATCT GTTACAAGGT GGGGAAATTT TATGAGCTGT ACCACATGGA TGCTCTTATT
GGAGTCAGTG AACTGGGGCT GGTATTCATG AAAGGCAACT GGGCCCATTC TGGCTTTCCT
GAAATTGCAT TTGGCCGTTA TTCAGATTCC CTGGTGCAGA AGGGCTATAA AGTAGCACGA
GTGGAACAGA CTGAGACTCC AGAAATGATG GAGGCACGAT GTAGAAAGAT GGCACATATA
TCCAAGTATG ATAGAGTGGT GAGGAGGGAG ATCTGTAGGA TCATTACCAA GGGTACACAG
ACTTACAGTG TGCTGGAAGG TGATCCCTCT GAGAACTACA GTAAGTATCT TCTTAGCCTC
AAAGAAAAAG AGGAAGATTC TTCTGGCCAT ACTCGTGCAT ATGGTGTGTG CTTTGTTGAT
ACTTCACTGG GAAAGTTTTT CATAGGTCAG TTTTCAGATG ATCGCCATTG TTCGAGATTT
AGGACTCTAG TGGCACACTA TCCCCCAGTA CAAGTTTTAT TTGAAAAAGG AAATCTCTCA
AAGGAAACTA AAACAATTCT AAAGAGTTCA TTGTCCTGTT CTCTTCAGGA AGGTCTGATA
CCCGGCTCCC AGTTTTGGGA TGCATCCAAA ACTTTGAGAA CTCTCCTTGA GGAAGAATAT
TTTAGGGAAA AGCTAAGTGA TGGCATTGGG GTGATGTTAC CCCAGGTGCT TAAAGGTATG
ACTTCAGAGT CTGATTCCAT TGGGTTGACA CCAGGAGAGA AAAGTGAATT GGCCCTCTCT
GCTCTAGGTG GTTGTGTCTT CTACCTCAAA AAATGCCTTA TTGATCAGGA GCTTTTATCA
ATGGCTAATT TTGAAGAATA TATTCCCTTG GATTCTGACA CAGTCAGCAC TACAAGATCT
GGTGCTATCT TCACCAAAGC CTATCAACGA ATGGTGCTAG ATGCAGTGAC ATTAAACAAC
TTGGAGATTT TTCTGAATGG AACAAATGGT TCTACTGAAG GAACCCTACT AGAGAGGGTT
GATACTTGCC ATACTCCTTT TGGTAAGCGG CTCCTAAAGC AATGGCTTTG TGCCCCACTC
TGTAACCATT ATGCTATTAA TGATCGTCTA GATGCCATAG AAGACCTCAT GGTTGTGCCT
GACAAAATCT CCGAAGTTGT AGAGCTTCTA AAGAAGCTTC CAGATCTTGA GAGGCTACTC
AGTAAAATTC ATAATGTTGG GTCTCCCCTG AAGAGTCAGA ACCACCCAGA CAGCAGGGCT
ATAATGTATG AAGAAACTAC ATACAGCAAG AAGAAGATTA TTGATTTTCT TTCTGCTCTG
GAAGGATTCA AAGTAATGTG TAAAATTATA GGGATCATGG AAGAAGTTGC TGATGGTTTT
AAGTCTAAAA TCCTTAAGCA GGTCATCTCT CTGCAGACAA AAAATCCTGA AGGTCGTTTT
CCTGATTTGA CTGTAGAATT GAACCGATGG GATACAGCCT TTGACCATGA AAAGGCTCGA
AAGACTGGAC TTATTACTCC CAAAGCAGGC TTTGACTCTG ATTATGACCA AGCTCTTGCT
GACATAAGAG AAAATGAACA GAGCCTCCTG GAATACCTAG AGAAACAGCG CAACAGAATT
GGCTGTAGGA CCATAGTCTA TTGGGGGATT GGTAGGAACC GTTACCAGCT GGAAATTCCT
GAGAATTTCA CCACTCGCAA TTTGCCAGAA GAATACGAGT TGAAATCTAC CAAGAAGGGC
TGTAAACGAT ACTGGACCAA AACTATTGAA AAGAAGTTGG CTAATCTCAT AAATGCTGAA
GAACGGAGGG ATGTATCATT GAAGGACTGC ATGCGGCGAC TGTTCTATAA CTTTGATAAA
AATTACAAGG ACTGGCAGTC TGCTGTAGAG TGTATCGCAG TGTTGGATGT TTTACTGTGC
CTGGCTAACT ATAGTCGAGG GGGTGATGGT CCTATGTGTC GCCCAGTAAT TCTGTTGCCG
GAAGATACCC CCCCCTTCTT AGAGCTTAAA GGATCACGCC ATCCTTGCAT TACGAAGACT
TTTTTTGGAG ATGATTTTAT TCCTAATGAC ATTCTAATAG GCTGTGAGGA AGAGGAGCAG
GAAAATGGCA AAGCCTATTG TGTGCTTGTT ACTGGACCAA ATATGGGGGG CAAGTCTACG
CTTATGAGAC AGGCTGGCTT ATTAGCTGTA ATGGCCCAGA TGGGTTGTTA CGTCCCTGCT
GAAGTGTGCA GGCTCACACC AATTGATAGA GTGTTTACTA GACTTGGTGC CTCAGACAGA
ATAATGTCAG GTGAAAGTAC ATTTTTTGTT GAATTAAGTG AAACTGCCAG CATACTCATG
CATGCAACAG CACATTCTCT GGTGCTTGTG GATGAATTAG GAAGAGGTAC TGCAACATTT
GATGGGACGG CAATAGCAAA TGCAGTTGTT AAAGAACTTG CTGAGACTAT AAAATGTCGT
ACATTATTTT CAACTCACTA CCATTCATTA GTAGAAGATT ATTCTCAAAA TGTTGCTGTG
CGCCTAGGAC ATATGGCATG CATGGTAGAA AATGAATGTG AAGACCCCAG CCAGGAGACT
ATTACGTTCC TCTATAAATT CATTAAGGGA GCTTGTCCTA AAAGCTATGG CTTTAATGCA
GCAAGGCTTG CTAATCTCCC AGAGGAAGTT ATTCAAAAGG GACATAGAAA AGCAAGAGAA
TTTGAGAAGA TGAATCAGTC ACTACGATTA TTTCGGGAAG TTTGCCTGGC TAGTGAAAGG
TCAACTGTAG ATGCTGAAGC TGTCCATAAA TTGCTGACTT TGATTAAGGA ATTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001268422.1
CDS889..4065
Misc Feature(1)595..597
Misc Feature(2)1201..3990
Misc Feature(3)1201..1557
Misc Feature(4)1594..2058
Misc Feature(5)2197..>2463
Misc Feature(6)2776..3054
Misc Feature(7)3253..3921
Misc Feature(8)3382..3405
Misc Feature(9)order(3391..3396,3400..3408,3514..3516,3619..3624,3724..3726)
Misc Feature(10)3505..3516
Misc Feature(11)3529..3570
Misc Feature(12)3607..3624
Misc Feature(13)3631..3642
Misc Feature(14)3712..3732
Exon (1)1..412
Exon (2)413..609
Exon (3)610..3154
Exon (4)3155..3420
Exon (5)3421..3538
Exon (6)3539..3628
Exon (7)3629..3783
Exon (8)3784..3983
Exon (9)3984..4158
Translation

Target ORF information:

RefSeq Version NM_001281493.1
Organism Homo sapiens(Human)
Definition Homo sapiens mutS homolog 6 (MSH6), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001281493.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGTGACTG GAAATGGCTC TCTTAAAAGG AAAAGCTCTA GGAAGGAAAC GCCCTCAGCC 
ACCAAACAAG CAACTAGCAT TTCATCAGAA ACCAAGAATA CTTTGAGAGC TTTCTCTGCC
CCTCAAAATT CTGAATCCCA AGCCCACGTT AGTGGAGGTG GTGATGACAG TAGTCGCCCT
ACTGTTTGGT ATCATGAAAC TTTAGAATGG CTTAAGGAGG AAAAGAGAAG AGATGAGCAC
AGGAGGAGGC CTGATCACCC CGATTTTGAT GCATCTACAC TCTATGTGCC TGAGGATTTC
CTCAATTCTT GTACTCCTGG GATGAGGAAG TGGTGGCAGA TTAAGTCTCA GAACTTTGAT
CTTGTCATCT GTTACAAGGT GGGGAAATTT TATGAGCTGT ACCACATGGA TGCTCTTATT
GGAGTCAGTG AACTGGGGCT GGTATTCATG AAAGGCAACT GGGCCCATTC TGGCTTTCCT
GAAATTGCAT TTGGCCGTTA TTCAGATTCC CTGGTGCAGA AGGGCTATAA AGTAGCACGA
GTGGAACAGA CTGAGACTCC AGAAATGATG GAGGCACGAT GTAGAAAGAT GGCACATATA
TCCAAGTATG ATAGAGTGGT GAGGAGGGAG ATCTGTAGGA TCATTACCAA GGGTACACAG
ACTTACAGTG TGCTGGAAGG TGATCCCTCT GAGAACTACA GTAAGTATCT TCTTAGCCTC
AAAGAAAAAG AGGAAGATTC TTCTGGCCAT ACTCGTGCAT ATGGTGTGTG CTTTGTTGAT
ACTTCACTGG GAAAGTTTTT CATAGGTCAG TTTTCAGATG ATCGCCATTG TTCGAGATTT
AGGACTCTAG TGGCACACTA TCCCCCAGTA CAAGTTTTAT TTGAAAAAGG AAATCTCTCA
AAGGAAACTA AAACAATTCT AAAGAGTTCA TTGTCCTGTT CTCTTCAGGA AGGTCTGATA
CCCGGCTCCC AGTTTTGGGA TGCATCCAAA ACTTTGAGAA CTCTCCTTGA GGAAGAATAT
TTTAGGGAAA AGCTAAGTGA TGGCATTGGG GTGATGTTAC CCCAGGTGCT TAAAGGTATG
ACTTCAGAGT CTGATTCCAT TGGGTTGACA CCAGGAGAGA AAAGTGAATT GGCCCTCTCT
GCTCTAGGTG GTTGTGTCTT CTACCTCAAA AAATGCCTTA TTGATCAGGA GCTTTTATCA
ATGGCTAATT TTGAAGAATA TATTCCCTTG GATTCTGACA CAGTCAGCAC TACAAGATCT
GGTGCTATCT TCACCAAAGC CTATCAACGA ATGGTGCTAG ATGCAGTGAC ATTAAACAAC
TTGGAGATTT TTCTGAATGG AACAAATGGT TCTACTGAAG GAACCCTACT AGAGAGGGTT
GATACTTGCC ATACTCCTTT TGGTAAGCGG CTCCTAAAGC AATGGCTTTG TGCCCCACTC
TGTAACCATT ATGCTATTAA TGATCGTCTA GATGCCATAG AAGACCTCAT GGTTGTGCCT
GACAAAATCT CCGAAGTTGT AGAGCTTCTA AAGAAGCTTC CAGATCTTGA GAGGCTACTC
AGTAAAATTC ATAATGTTGG GTCTCCCCTG AAGAGTCAGA ACCACCCAGA CAGCAGGGCT
ATAATGTATG AAGAAACTAC ATACAGCAAG AAGAAGATTA TTGATTTTCT TTCTGCTCTG
GAAGGATTCA AAGTAATGTG TAAAATTATA GGGATCATGG AAGAAGTTGC TGATGGTTTT
AAGTCTAAAA TCCTTAAGCA GGTCATCTCT CTGCAGACAA AAAATCCTGA AGGTCGTTTT
CCTGATTTGA CTGTAGAATT GAACCGATGG GATACAGCCT TTGACCATGA AAAGGCTCGA
AAGACTGGAC TTATTACTCC CAAAGCAGGC TTTGACTCTG ATTATGACCA AGCTCTTGCT
GACATAAGAG AAAATGAACA GAGCCTCCTG GAATACCTAG AGAAACAGCG CAACAGAATT
GGCTGTAGGA CCATAGTCTA TTGGGGGATT GGTAGGAACC GTTACCAGCT GGAAATTCCT
GAGAATTTCA CCACTCGCAA TTTGCCAGAA GAATACGAGT TGAAATCTAC CAAGAAGGGC
TGTAAACGAT ACTGGACCAA AACTATTGAA AAGAAGTTGG CTAATCTCAT AAATGCTGAA
GAACGGAGGG ATGTATCATT GAAGGACTGC ATGCGGCGAC TGTTCTATAA CTTTGATAAA
AATTACAAGG ACTGGCAGTC TGCTGTAGAG TGTATCGCAG TGTTGGATGT TTTACTGTGC
CTGGCTAACT ATAGTCGAGG GGGTGATGGT CCTATGTGTC GCCCAGTAAT TCTGTTGCCG
GAAGATACCC CCCCCTTCTT AGAGCTTAAA GGATCACGCC ATCCTTGCAT TACGAAGACT
TTTTTTGGAG ATGATTTTAT TCCTAATGAC ATTCTAATAG GCTGTGAGGA AGAGGAGCAG
GAAAATGGCA AAGCCTATTG TGTGCTTGTT ACTGGACCAA ATATGGGGGG CAAGTCTACG
CTTATGAGAC AGGCTGGCTT ATTAGCTGTA ATGGCCCAGA TGGGTTGTTA CGTCCCTGCT
GAAGTGTGCA GGCTCACACC AATTGATAGA GTGTTTACTA GACTTGGTGC CTCAGACAGA
ATAATGTCAG GTGAAAGTAC ATTTTTTGTT GAATTAAGTG AAACTGCCAG CATACTCATG
CATGCAACAG CACATTCTCT GGTGCTTGTG GATGAATTAG GAAGAGGTAC TGCAACATTT
GATGGGACGG CAATAGCAAA TGCAGTTGTT AAAGAACTTG CTGAGACTAT AAAATGTCGT
ACATTATTTT CAACTCACTA CCATTCATTA GTAGAAGATT ATTCTCAAAA TGTTGCTGTG
CGCCTAGGAC ATATGGCATG CATGGTAGAA AATGAATGTG AAGACCCCAG CCAGGAGACT
ATTACGTTCC TCTATAAATT CATTAAGGGA GCTTGTCCTA AAAGCTATGG CTTTAATGCA
GCAAGGCTTG CTAATCTCCC AGAGGAAGTT ATTCAAAAGG GACATAGAAA AGCAAGAGAA
TTTGAGAAGA TGAATCAGTC ACTACGATTA TTTCGGGAAG TTTGCCTGGC TAGTGAAAGG
TCAACTGTAG ATGCTGAAGC TGTCCATAAA TTGCTGACTT TGATTAAGGA ATTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22411
Clone ID Related Accession (Same CDS sequence) NM_001281493.1 , NM_001281494.1
Accession Version NM_001281494.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3177bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product DNA mismatch repair protein Msh6 isoform 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK304735.1, AC006509.15 and BC071594.1. Transcript Variant: This variant (4) contains an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a dowstream start codon compared to variant 1. The encoded isoform (3) is shorter and has a distinct N-terminus compared to isoform 1. Variants 3 and 4 encode the same protein (isoform 3). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304735.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2142853 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGTGACTG GAAATGGCTC TCTTAAAAGG AAAAGCTCTA GGAAGGAAAC GCCCTCAGCC 
ACCAAACAAG CAACTAGCAT TTCATCAGAA ACCAAGAATA CTTTGAGAGC TTTCTCTGCC
CCTCAAAATT CTGAATCCCA AGCCCACGTT AGTGGAGGTG GTGATGACAG TAGTCGCCCT
ACTGTTTGGT ATCATGAAAC TTTAGAATGG CTTAAGGAGG AAAAGAGAAG AGATGAGCAC
AGGAGGAGGC CTGATCACCC CGATTTTGAT GCATCTACAC TCTATGTGCC TGAGGATTTC
CTCAATTCTT GTACTCCTGG GATGAGGAAG TGGTGGCAGA TTAAGTCTCA GAACTTTGAT
CTTGTCATCT GTTACAAGGT GGGGAAATTT TATGAGCTGT ACCACATGGA TGCTCTTATT
GGAGTCAGTG AACTGGGGCT GGTATTCATG AAAGGCAACT GGGCCCATTC TGGCTTTCCT
GAAATTGCAT TTGGCCGTTA TTCAGATTCC CTGGTGCAGA AGGGCTATAA AGTAGCACGA
GTGGAACAGA CTGAGACTCC AGAAATGATG GAGGCACGAT GTAGAAAGAT GGCACATATA
TCCAAGTATG ATAGAGTGGT GAGGAGGGAG ATCTGTAGGA TCATTACCAA GGGTACACAG
ACTTACAGTG TGCTGGAAGG TGATCCCTCT GAGAACTACA GTAAGTATCT TCTTAGCCTC
AAAGAAAAAG AGGAAGATTC TTCTGGCCAT ACTCGTGCAT ATGGTGTGTG CTTTGTTGAT
ACTTCACTGG GAAAGTTTTT CATAGGTCAG TTTTCAGATG ATCGCCATTG TTCGAGATTT
AGGACTCTAG TGGCACACTA TCCCCCAGTA CAAGTTTTAT TTGAAAAAGG AAATCTCTCA
AAGGAAACTA AAACAATTCT AAAGAGTTCA TTGTCCTGTT CTCTTCAGGA AGGTCTGATA
CCCGGCTCCC AGTTTTGGGA TGCATCCAAA ACTTTGAGAA CTCTCCTTGA GGAAGAATAT
TTTAGGGAAA AGCTAAGTGA TGGCATTGGG GTGATGTTAC CCCAGGTGCT TAAAGGTATG
ACTTCAGAGT CTGATTCCAT TGGGTTGACA CCAGGAGAGA AAAGTGAATT GGCCCTCTCT
GCTCTAGGTG GTTGTGTCTT CTACCTCAAA AAATGCCTTA TTGATCAGGA GCTTTTATCA
ATGGCTAATT TTGAAGAATA TATTCCCTTG GATTCTGACA CAGTCAGCAC TACAAGATCT
GGTGCTATCT TCACCAAAGC CTATCAACGA ATGGTGCTAG ATGCAGTGAC ATTAAACAAC
TTGGAGATTT TTCTGAATGG AACAAATGGT TCTACTGAAG GAACCCTACT AGAGAGGGTT
GATACTTGCC ATACTCCTTT TGGTAAGCGG CTCCTAAAGC AATGGCTTTG TGCCCCACTC
TGTAACCATT ATGCTATTAA TGATCGTCTA GATGCCATAG AAGACCTCAT GGTTGTGCCT
GACAAAATCT CCGAAGTTGT AGAGCTTCTA AAGAAGCTTC CAGATCTTGA GAGGCTACTC
AGTAAAATTC ATAATGTTGG GTCTCCCCTG AAGAGTCAGA ACCACCCAGA CAGCAGGGCT
ATAATGTATG AAGAAACTAC ATACAGCAAG AAGAAGATTA TTGATTTTCT TTCTGCTCTG
GAAGGATTCA AAGTAATGTG TAAAATTATA GGGATCATGG AAGAAGTTGC TGATGGTTTT
AAGTCTAAAA TCCTTAAGCA GGTCATCTCT CTGCAGACAA AAAATCCTGA AGGTCGTTTT
CCTGATTTGA CTGTAGAATT GAACCGATGG GATACAGCCT TTGACCATGA AAAGGCTCGA
AAGACTGGAC TTATTACTCC CAAAGCAGGC TTTGACTCTG ATTATGACCA AGCTCTTGCT
GACATAAGAG AAAATGAACA GAGCCTCCTG GAATACCTAG AGAAACAGCG CAACAGAATT
GGCTGTAGGA CCATAGTCTA TTGGGGGATT GGTAGGAACC GTTACCAGCT GGAAATTCCT
GAGAATTTCA CCACTCGCAA TTTGCCAGAA GAATACGAGT TGAAATCTAC CAAGAAGGGC
TGTAAACGAT ACTGGACCAA AACTATTGAA AAGAAGTTGG CTAATCTCAT AAATGCTGAA
GAACGGAGGG ATGTATCATT GAAGGACTGC ATGCGGCGAC TGTTCTATAA CTTTGATAAA
AATTACAAGG ACTGGCAGTC TGCTGTAGAG TGTATCGCAG TGTTGGATGT TTTACTGTGC
CTGGCTAACT ATAGTCGAGG GGGTGATGGT CCTATGTGTC GCCCAGTAAT TCTGTTGCCG
GAAGATACCC CCCCCTTCTT AGAGCTTAAA GGATCACGCC ATCCTTGCAT TACGAAGACT
TTTTTTGGAG ATGATTTTAT TCCTAATGAC ATTCTAATAG GCTGTGAGGA AGAGGAGCAG
GAAAATGGCA AAGCCTATTG TGTGCTTGTT ACTGGACCAA ATATGGGGGG CAAGTCTACG
CTTATGAGAC AGGCTGGCTT ATTAGCTGTA ATGGCCCAGA TGGGTTGTTA CGTCCCTGCT
GAAGTGTGCA GGCTCACACC AATTGATAGA GTGTTTACTA GACTTGGTGC CTCAGACAGA
ATAATGTCAG GTGAAAGTAC ATTTTTTGTT GAATTAAGTG AAACTGCCAG CATACTCATG
CATGCAACAG CACATTCTCT GGTGCTTGTG GATGAATTAG GAAGAGGTAC TGCAACATTT
GATGGGACGG CAATAGCAAA TGCAGTTGTT AAAGAACTTG CTGAGACTAT AAAATGTCGT
ACATTATTTT CAACTCACTA CCATTCATTA GTAGAAGATT ATTCTCAAAA TGTTGCTGTG
CGCCTAGGAC ATATGGCATG CATGGTAGAA AATGAATGTG AAGACCCCAG CCAGGAGACT
ATTACGTTCC TCTATAAATT CATTAAGGGA GCTTGTCCTA AAAGCTATGG CTTTAATGCA
GCAAGGCTTG CTAATCTCCC AGAGGAAGTT ATTCAAAAGG GACATAGAAA AGCAAGAGAA
TTTGAGAAGA TGAATCAGTC ACTACGATTA TTTCGGGAAG TTTGCCTGGC TAGTGAAAGG
TCAACTGTAG ATGCTGAAGC TGTCCATAAA TTGCTGACTT TGATTAAGGA ATTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001268423.1
CDS794..3970
Misc Feature(1)482..484
Misc Feature(2)1106..3895
Misc Feature(3)1106..1462
Misc Feature(4)1499..1963
Misc Feature(5)2102..>2368
Misc Feature(6)2681..2959
Misc Feature(7)3158..3826
Misc Feature(8)3287..3310
Misc Feature(9)order(3296..3301,3305..3313,3419..3421,3524..3529,3629..3631)
Misc Feature(10)3410..3421
Misc Feature(11)3434..3475
Misc Feature(12)3512..3529
Misc Feature(13)3536..3547
Misc Feature(14)3617..3637
Exon (1)1..151
Exon (2)152..348
Exon (3)349..518
Exon (4)519..3059
Exon (5)3060..3325
Exon (6)3326..3443
Exon (7)3444..3533
Exon (8)3534..3688
Exon (9)3689..3888
Exon (10)3889..4063
Translation

Target ORF information:

RefSeq Version NM_001281494.1
Organism Homo sapiens(Human)
Definition Homo sapiens mutS homolog 6 (MSH6), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001281494.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
ATGGTGACTG GAAATGGCTC TCTTAAAAGG AAAAGCTCTA GGAAGGAAAC GCCCTCAGCC 
ACCAAACAAG CAACTAGCAT TTCATCAGAA ACCAAGAATA CTTTGAGAGC TTTCTCTGCC
CCTCAAAATT CTGAATCCCA AGCCCACGTT AGTGGAGGTG GTGATGACAG TAGTCGCCCT
ACTGTTTGGT ATCATGAAAC TTTAGAATGG CTTAAGGAGG AAAAGAGAAG AGATGAGCAC
AGGAGGAGGC CTGATCACCC CGATTTTGAT GCATCTACAC TCTATGTGCC TGAGGATTTC
CTCAATTCTT GTACTCCTGG GATGAGGAAG TGGTGGCAGA TTAAGTCTCA GAACTTTGAT
CTTGTCATCT GTTACAAGGT GGGGAAATTT TATGAGCTGT ACCACATGGA TGCTCTTATT
GGAGTCAGTG AACTGGGGCT GGTATTCATG AAAGGCAACT GGGCCCATTC TGGCTTTCCT
GAAATTGCAT TTGGCCGTTA TTCAGATTCC CTGGTGCAGA AGGGCTATAA AGTAGCACGA
GTGGAACAGA CTGAGACTCC AGAAATGATG GAGGCACGAT GTAGAAAGAT GGCACATATA
TCCAAGTATG ATAGAGTGGT GAGGAGGGAG ATCTGTAGGA TCATTACCAA GGGTACACAG
ACTTACAGTG TGCTGGAAGG TGATCCCTCT GAGAACTACA GTAAGTATCT TCTTAGCCTC
AAAGAAAAAG AGGAAGATTC TTCTGGCCAT ACTCGTGCAT ATGGTGTGTG CTTTGTTGAT
ACTTCACTGG GAAAGTTTTT CATAGGTCAG TTTTCAGATG ATCGCCATTG TTCGAGATTT
AGGACTCTAG TGGCACACTA TCCCCCAGTA CAAGTTTTAT TTGAAAAAGG AAATCTCTCA
AAGGAAACTA AAACAATTCT AAAGAGTTCA TTGTCCTGTT CTCTTCAGGA AGGTCTGATA
CCCGGCTCCC AGTTTTGGGA TGCATCCAAA ACTTTGAGAA CTCTCCTTGA GGAAGAATAT
TTTAGGGAAA AGCTAAGTGA TGGCATTGGG GTGATGTTAC CCCAGGTGCT TAAAGGTATG
ACTTCAGAGT CTGATTCCAT TGGGTTGACA CCAGGAGAGA AAAGTGAATT GGCCCTCTCT
GCTCTAGGTG GTTGTGTCTT CTACCTCAAA AAATGCCTTA TTGATCAGGA GCTTTTATCA
ATGGCTAATT TTGAAGAATA TATTCCCTTG GATTCTGACA CAGTCAGCAC TACAAGATCT
GGTGCTATCT TCACCAAAGC CTATCAACGA ATGGTGCTAG ATGCAGTGAC ATTAAACAAC
TTGGAGATTT TTCTGAATGG AACAAATGGT TCTACTGAAG GAACCCTACT AGAGAGGGTT
GATACTTGCC ATACTCCTTT TGGTAAGCGG CTCCTAAAGC AATGGCTTTG TGCCCCACTC
TGTAACCATT ATGCTATTAA TGATCGTCTA GATGCCATAG AAGACCTCAT GGTTGTGCCT
GACAAAATCT CCGAAGTTGT AGAGCTTCTA AAGAAGCTTC CAGATCTTGA GAGGCTACTC
AGTAAAATTC ATAATGTTGG GTCTCCCCTG AAGAGTCAGA ACCACCCAGA CAGCAGGGCT
ATAATGTATG AAGAAACTAC ATACAGCAAG AAGAAGATTA TTGATTTTCT TTCTGCTCTG
GAAGGATTCA AAGTAATGTG TAAAATTATA GGGATCATGG AAGAAGTTGC TGATGGTTTT
AAGTCTAAAA TCCTTAAGCA GGTCATCTCT CTGCAGACAA AAAATCCTGA AGGTCGTTTT
CCTGATTTGA CTGTAGAATT GAACCGATGG GATACAGCCT TTGACCATGA AAAGGCTCGA
AAGACTGGAC TTATTACTCC CAAAGCAGGC TTTGACTCTG ATTATGACCA AGCTCTTGCT
GACATAAGAG AAAATGAACA GAGCCTCCTG GAATACCTAG AGAAACAGCG CAACAGAATT
GGCTGTAGGA CCATAGTCTA TTGGGGGATT GGTAGGAACC GTTACCAGCT GGAAATTCCT
GAGAATTTCA CCACTCGCAA TTTGCCAGAA GAATACGAGT TGAAATCTAC CAAGAAGGGC
TGTAAACGAT ACTGGACCAA AACTATTGAA AAGAAGTTGG CTAATCTCAT AAATGCTGAA
GAACGGAGGG ATGTATCATT GAAGGACTGC ATGCGGCGAC TGTTCTATAA CTTTGATAAA
AATTACAAGG ACTGGCAGTC TGCTGTAGAG TGTATCGCAG TGTTGGATGT TTTACTGTGC
CTGGCTAACT ATAGTCGAGG GGGTGATGGT CCTATGTGTC GCCCAGTAAT TCTGTTGCCG
GAAGATACCC CCCCCTTCTT AGAGCTTAAA GGATCACGCC ATCCTTGCAT TACGAAGACT
TTTTTTGGAG ATGATTTTAT TCCTAATGAC ATTCTAATAG GCTGTGAGGA AGAGGAGCAG
GAAAATGGCA AAGCCTATTG TGTGCTTGTT ACTGGACCAA ATATGGGGGG CAAGTCTACG
CTTATGAGAC AGGCTGGCTT ATTAGCTGTA ATGGCCCAGA TGGGTTGTTA CGTCCCTGCT
GAAGTGTGCA GGCTCACACC AATTGATAGA GTGTTTACTA GACTTGGTGC CTCAGACAGA
ATAATGTCAG GTGAAAGTAC ATTTTTTGTT GAATTAAGTG AAACTGCCAG CATACTCATG
CATGCAACAG CACATTCTCT GGTGCTTGTG GATGAATTAG GAAGAGGTAC TGCAACATTT
GATGGGACGG CAATAGCAAA TGCAGTTGTT AAAGAACTTG CTGAGACTAT AAAATGTCGT
ACATTATTTT CAACTCACTA CCATTCATTA GTAGAAGATT ATTCTCAAAA TGTTGCTGTG
CGCCTAGGAC ATATGGCATG CATGGTAGAA AATGAATGTG AAGACCCCAG CCAGGAGACT
ATTACGTTCC TCTATAAATT CATTAAGGGA GCTTGTCCTA AAAGCTATGG CTTTAATGCA
GCAAGGCTTG CTAATCTCCC AGAGGAAGTT ATTCAAAAGG GACATAGAAA AGCAAGAGAA
TTTGAGAAGA TGAATCAGTC ACTACGATTA TTTCGGGAAG TTTGCCTGGC TAGTGAAAGG
TCAACTGTAG ATGCTGAAGC TGTCCATAAA TTGCTGACTT TGATTAAGGA ATTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27543
Clone ID Related Accession (Same CDS sequence) NM_001281492.1
Accession Version NM_001281492.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3693bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-23
Organism Homo sapiens(Human)
Product DNA mismatch repair protein Msh6 isoform 2
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC071594.1 and AK293921.1. Transcript Variant: This variant (2) uses an alternate splice site and lacks two exons in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK293921.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
ATGTCGCGAC AGAGCACCCT GTACAGCTTC TTCCCCAAGT CTCCGGCGCT GAGTGATGCC 
AACAAGGCCT CGGCCAGGGC CTCACGCGAA GGCGGCCGTG CCGCCGCTGC CCCCGGGGCC
TCTCCTTCCC CAGGCGGGGA TGCGGCCTGG AGCGAGGCTG GGCCTGGGCC CAGGCCCTTG
GCGCGCTCCG CGTCACCGCC CAAGGCGAAG AACCTCAACG GAGGGCTGCG GAGATCGGTA
GGCACAACTT ACGTAACAGA TAAGAGTGAA GAAGATAATG AAATTGAGAG TGAAGAGGAA
GTACAGCCTA AGACACAAGG ATCTAGGCGA AGTAGCCGCC AAATAAAAAA ACGAAGGGTC
ATATCAGATT CTGAGAGTGA CATTGGTGGC TCTGATGTGG AATTTAAGCC AGACACTAAG
GAGGAAGGAA GCAGTGATGA AATAAGCAGT GGAGTGGGGG ATAGTGAGAG TGAAGGCCTG
AACAGCCCTG TCAAAGTTGC TCGAAAGCGG AAGAGAATGG TGACTGGAAA TGGCTCTCTT
AAAAGGAAAA GCTCTAGGAA GGAAACGCCC TCAGCCACCA AACAAGCAAC TAGCATTTCA
TCAGAAACCA AGAATACTTT GAGAGCTTTC TCTGCCCCTC AAAATTCTGA ATCCCAAGCC
CACGTTAGTG GAGGTGGTGA TGACAGTAGT CGCCCTACTG TTTGGTATCA TGAAACTTTA
GAATGGCTTA AGGAGGAAAA GAGAAGAGAT GAGCACAGGA GGAGGCCTGA TCACCCCGAT
TTTGATGCAT CTACACTCTA TGTGCCTGAG GATTTCCTCA ATTCTTGTAC TCCTGGGATG
AGGAAGTGGT GGCAGATTAA GTCTCAGAAC TTTGATCTTG TCATCTGTTA CAAGGTGGGG
AAATTTTATG AGCTGTACCA CATGGATGCT CTTATTGGAG TCAGTGAACT GGGGCTGGTA
TTCATGAAAG GCAACTGGGC CCATTCTGGC TTTCCTGAAA TTGCATTTGG CCGTTATTCA
GATTCCCTGG TGCAGAAGGG CTATAAAGTA GCACGAGTGG AACAGACTGA GACTCCAGAA
ATGATGGAGG CACGATGTAG AAAGATGGCA CATATATCCA AGTATGATAG AGTGGTGAGG
AGGGAGATCT GTAGGATCAT TACCAAGGGT ACACAGACTT ACAGTGTGCT GGAAGGTGAT
CCCTCTGAGA ACTACAGTAA GTATCTTCTT AGCCTCAAAG AAAAAGAGGA AGATTCTTCT
GGCCATACTC GTGCATATGG TGTGTGCTTT GTTGATACTT CACTGGGAAA GTTTTTCATA
GGTCAGTTTT CAGATGATCG CCATTGTTCG AGATTTAGGA CTCTAGTGGC ACACTATCCC
CCAGTACAAG TTTTATTTGA AAAAGGAAAT CTCTCAAAGG AAACTAAAAC AATTCTAAAG
AGTTCATTGT CCTGTTCTCT TCAGGAAGGT CTGATACCCG GCTCCCAGTT TTGGGATGCA
TCCAAAACTT TGAGAACTCT CCTTGAGGAA GAATATTTTA GGGAAAAGCT AAGTGATGGC
ATTGGGGTGA TGTTACCCCA GGTGCTTAAA GGTATGACTT CAGAGTCTGA TTCCATTGGG
TTGACACCAG GAGAGAAAAG TGAATTGGCC CTCTCTGCTC TAGGTGGTTG TGTCTTCTAC
CTCAAAAAAT GCCTTATTGA TCAGGAGCTT TTATCAATGG CTAATTTTGA AGAATATATT
CCCTTGGATT CTGACACAGT CAGCACTACA AGATCTGGTG CTATCTTCAC CAAAGCCTAT
CAACGAATGG TGCTAGATGC AGTGACATTA AACAACTTGG AGATTTTTCT GAATGGAACA
AATGGTTCTA CTGAAGGAAC CCTACTAGAG AGGGTTGATA CTTGCCATAC TCCTTTTGGT
AAGCGGCTCC TAAAGCAATG GCTTTGTGCC CCACTCTGTA ACCATTATGC TATTAATGAT
CGTCTAGATG CCATAGAAGA CCTCATGGTT GTGCCTGACA AAATCTCCGA AGTTGTAGAG
CTTCTAAAGA AGCTTCCAGA TCTTGAGAGG CTACTCAGTA AAATTCATAA TGTTGGGTCT
CCCCTGAAGA GTCAGAACCA CCCAGACAGC AGGGCTATAA TGTATGAAGA AACTACATAC
AGCAAGAAGA AGATTATTGA TTTTCTTTCT GCTCTGGAAG GATTCAAAGT AATGTGTAAA
ATTATAGGGA TCATGGAAGA AGTTGCTGAT GGTTTTAAGT CTAAAATCCT TAAGCAGGTC
ATCTCTCTGC AGACAAAAAA TCCTGAAGGT CGTTTTCCTG ATTTGACTGT AGAATTGAAC
CGATGGGATA CAGCCTTTGA CCATGAAAAG GCTCGAAAGA CTGGACTTAT TACTCCCAAA
GCAGGCTTTG ACTCTGATTA TGACCAAGCT CTTGCTGACA TAAGAGAAAA TGAACAGAGC
CTCCTGGAAT ACCTAGAGAA ACAGCGCAAC AGAATTGGCT GTAGGACCAT AGTCTATTGG
GGGATTGGTA GGAACCGTTA CCAGCTGGAA ATTCCTGAGA ATTTCACCAC TCGCAATTTG
CCAGAAGAAT ACGAGTTGAA ATCTACCAAG AAGGGCTGTA AACGATACTG GACCAAAACT
ATTGAAAAGA AGTTGGCTAA TCTCATAAAT GCTGAAGAAC GGAGGGATGT ATCATTGAAG
GACTGCATGC GGCGACTGTT CTATAACTTT GATAAAAATT ACAAGGACTG GCAGTCTGCT
GTAGAGTGTA TCGCAGTGTT GGATGTTTTA CTGTGCCTGG CTAACTATAG TCGAGGGGGT
GATGGTCCTA TGTGTCGCCC AGTAATTCTG TTGCCGGAAG ATACCCCCCC CTTCTTAGAG
CTTAAAGGAT CACGCCATCC TTGCATTACG AAGACTTTTT TTGGAGATGA TTTTATTCCT
AATGACATTC TAATAGGCTG TGAGGAAGAG GAGCAGGAAA ATGGCAAAGC CTATTGTGTG
CTTGTTACTG GACCAAATAT GGGGGGCAAG TCTACGCTTA TGAGACAGGC TGGCTTATTA
GCTGTAATGG CCCAGATGGG TTGTTACGTC CCTGCTGAAG TGTGCAGGCT CACACCAATT
GATAGAGTGT TTACTAGACT TGGTGCCTCA GACAGAATAA TGTCAGGTGA AAGTACATTT
TTTGTTGAAT TAAGTGAAAC TGCCAGCATA CTCATGCATG CAACAGCACA TTCTCTGGTG
CTTGTGGATG AATTAGGAAG AGGTACTGCA ACATTTGATG GGACGGCAAT AGCAAATGCA
GTTGTTAAAG AACTTGCTGA GACTATAAAA TGTCGTACAT TATTTTCAAC TCACTACCAT
TCATTAGTAG AAGATTATTC TCAAAATGTT GCTGTGCGCC TAGGACATAT GGCATGCATG
GTAGAAAATG AATGTGAAGA CCCCAGCCAG GAGACTATTA CGTTCCTCTA TAAATTCATT
AAGGGAGCTT GTCCTAAAAG CTATGGCTTT AATGCAGCAA GGCTTGCTAA TCTCCCAGAG
GAAGTTATTC AAAAGGGACA TAGAAAAGCA AGAGAATTTG AGAAGATGAA TCAGTCACTA
CGATTATTTC GGGAAGTTTG CCTGGCTAGT GAAAGGTCAA CTGTAGATGC TGAAGCTGTC
CATAAATTGC TGACTTTGAT TAAGGAATTA TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001268421.1
CDS153..3845
Misc Feature(1)15..17
Misc Feature(2)192..194
Misc Feature(3)273..275
Misc Feature(4)279..281
Misc Feature(5)360..362
Misc Feature(6)387..389
Misc Feature(7)981..3770
Misc Feature(8)981..1337
Misc Feature(9)1374..1838
Misc Feature(10)1977..>2243
Misc Feature(11)2556..2834
Misc Feature(12)3033..3701
Misc Feature(13)3162..3185
Misc Feature(14)order(3171..3176,3180..3188,3294..3296,3399..3404,3504..3506)
Misc Feature(15)3285..3296
Misc Feature(16)3309..3350
Misc Feature(17)3387..3404
Misc Feature(18)3411..3422
Misc Feature(19)3492..3512
Exon (1)1..389
Exon (2)390..2934
Exon (3)2935..3200
Exon (4)3201..3318
Exon (5)3319..3408
Exon (6)3409..3563
Exon (7)3564..3763
Exon (8)3764..3938
Translation

Target ORF information:

RefSeq Version NM_001281492.1
Organism Homo sapiens(Human)
Definition Homo sapiens mutS homolog 6 (MSH6), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001281492.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
ATGTCGCGAC AGAGCACCCT GTACAGCTTC TTCCCCAAGT CTCCGGCGCT GAGTGATGCC 
AACAAGGCCT CGGCCAGGGC CTCACGCGAA GGCGGCCGTG CCGCCGCTGC CCCCGGGGCC
TCTCCTTCCC CAGGCGGGGA TGCGGCCTGG AGCGAGGCTG GGCCTGGGCC CAGGCCCTTG
GCGCGCTCCG CGTCACCGCC CAAGGCGAAG AACCTCAACG GAGGGCTGCG GAGATCGGTA
GGCACAACTT ACGTAACAGA TAAGAGTGAA GAAGATAATG AAATTGAGAG TGAAGAGGAA
GTACAGCCTA AGACACAAGG ATCTAGGCGA AGTAGCCGCC AAATAAAAAA ACGAAGGGTC
ATATCAGATT CTGAGAGTGA CATTGGTGGC TCTGATGTGG AATTTAAGCC AGACACTAAG
GAGGAAGGAA GCAGTGATGA AATAAGCAGT GGAGTGGGGG ATAGTGAGAG TGAAGGCCTG
AACAGCCCTG TCAAAGTTGC TCGAAAGCGG AAGAGAATGG TGACTGGAAA TGGCTCTCTT
AAAAGGAAAA GCTCTAGGAA GGAAACGCCC TCAGCCACCA AACAAGCAAC TAGCATTTCA
TCAGAAACCA AGAATACTTT GAGAGCTTTC TCTGCCCCTC AAAATTCTGA ATCCCAAGCC
CACGTTAGTG GAGGTGGTGA TGACAGTAGT CGCCCTACTG TTTGGTATCA TGAAACTTTA
GAATGGCTTA AGGAGGAAAA GAGAAGAGAT GAGCACAGGA GGAGGCCTGA TCACCCCGAT
TTTGATGCAT CTACACTCTA TGTGCCTGAG GATTTCCTCA ATTCTTGTAC TCCTGGGATG
AGGAAGTGGT GGCAGATTAA GTCTCAGAAC TTTGATCTTG TCATCTGTTA CAAGGTGGGG
AAATTTTATG AGCTGTACCA CATGGATGCT CTTATTGGAG TCAGTGAACT GGGGCTGGTA
TTCATGAAAG GCAACTGGGC CCATTCTGGC TTTCCTGAAA TTGCATTTGG CCGTTATTCA
GATTCCCTGG TGCAGAAGGG CTATAAAGTA GCACGAGTGG AACAGACTGA GACTCCAGAA
ATGATGGAGG CACGATGTAG AAAGATGGCA CATATATCCA AGTATGATAG AGTGGTGAGG
AGGGAGATCT GTAGGATCAT TACCAAGGGT ACACAGACTT ACAGTGTGCT GGAAGGTGAT
CCCTCTGAGA ACTACAGTAA GTATCTTCTT AGCCTCAAAG AAAAAGAGGA AGATTCTTCT
GGCCATACTC GTGCATATGG TGTGTGCTTT GTTGATACTT CACTGGGAAA GTTTTTCATA
GGTCAGTTTT CAGATGATCG CCATTGTTCG AGATTTAGGA CTCTAGTGGC ACACTATCCC
CCAGTACAAG TTTTATTTGA AAAAGGAAAT CTCTCAAAGG AAACTAAAAC AATTCTAAAG
AGTTCATTGT CCTGTTCTCT TCAGGAAGGT CTGATACCCG GCTCCCAGTT TTGGGATGCA
TCCAAAACTT TGAGAACTCT CCTTGAGGAA GAATATTTTA GGGAAAAGCT AAGTGATGGC
ATTGGGGTGA TGTTACCCCA GGTGCTTAAA GGTATGACTT CAGAGTCTGA TTCCATTGGG
TTGACACCAG GAGAGAAAAG TGAATTGGCC CTCTCTGCTC TAGGTGGTTG TGTCTTCTAC
CTCAAAAAAT GCCTTATTGA TCAGGAGCTT TTATCAATGG CTAATTTTGA AGAATATATT
CCCTTGGATT CTGACACAGT CAGCACTACA AGATCTGGTG CTATCTTCAC CAAAGCCTAT
CAACGAATGG TGCTAGATGC AGTGACATTA AACAACTTGG AGATTTTTCT GAATGGAACA
AATGGTTCTA CTGAAGGAAC CCTACTAGAG AGGGTTGATA CTTGCCATAC TCCTTTTGGT
AAGCGGCTCC TAAAGCAATG GCTTTGTGCC CCACTCTGTA ACCATTATGC TATTAATGAT
CGTCTAGATG CCATAGAAGA CCTCATGGTT GTGCCTGACA AAATCTCCGA AGTTGTAGAG
CTTCTAAAGA AGCTTCCAGA TCTTGAGAGG CTACTCAGTA AAATTCATAA TGTTGGGTCT
CCCCTGAAGA GTCAGAACCA CCCAGACAGC AGGGCTATAA TGTATGAAGA AACTACATAC
AGCAAGAAGA AGATTATTGA TTTTCTTTCT GCTCTGGAAG GATTCAAAGT AATGTGTAAA
ATTATAGGGA TCATGGAAGA AGTTGCTGAT GGTTTTAAGT CTAAAATCCT TAAGCAGGTC
ATCTCTCTGC AGACAAAAAA TCCTGAAGGT CGTTTTCCTG ATTTGACTGT AGAATTGAAC
CGATGGGATA CAGCCTTTGA CCATGAAAAG GCTCGAAAGA CTGGACTTAT TACTCCCAAA
GCAGGCTTTG ACTCTGATTA TGACCAAGCT CTTGCTGACA TAAGAGAAAA TGAACAGAGC
CTCCTGGAAT ACCTAGAGAA ACAGCGCAAC AGAATTGGCT GTAGGACCAT AGTCTATTGG
GGGATTGGTA GGAACCGTTA CCAGCTGGAA ATTCCTGAGA ATTTCACCAC TCGCAATTTG
CCAGAAGAAT ACGAGTTGAA ATCTACCAAG AAGGGCTGTA AACGATACTG GACCAAAACT
ATTGAAAAGA AGTTGGCTAA TCTCATAAAT GCTGAAGAAC GGAGGGATGT ATCATTGAAG
GACTGCATGC GGCGACTGTT CTATAACTTT GATAAAAATT ACAAGGACTG GCAGTCTGCT
GTAGAGTGTA TCGCAGTGTT GGATGTTTTA CTGTGCCTGG CTAACTATAG TCGAGGGGGT
GATGGTCCTA TGTGTCGCCC AGTAATTCTG TTGCCGGAAG ATACCCCCCC CTTCTTAGAG
CTTAAAGGAT CACGCCATCC TTGCATTACG AAGACTTTTT TTGGAGATGA TTTTATTCCT
AATGACATTC TAATAGGCTG TGAGGAAGAG GAGCAGGAAA ATGGCAAAGC CTATTGTGTG
CTTGTTACTG GACCAAATAT GGGGGGCAAG TCTACGCTTA TGAGACAGGC TGGCTTATTA
GCTGTAATGG CCCAGATGGG TTGTTACGTC CCTGCTGAAG TGTGCAGGCT CACACCAATT
GATAGAGTGT TTACTAGACT TGGTGCCTCA GACAGAATAA TGTCAGGTGA AAGTACATTT
TTTGTTGAAT TAAGTGAAAC TGCCAGCATA CTCATGCATG CAACAGCACA TTCTCTGGTG
CTTGTGGATG AATTAGGAAG AGGTACTGCA ACATTTGATG GGACGGCAAT AGCAAATGCA
GTTGTTAAAG AACTTGCTGA GACTATAAAA TGTCGTACAT TATTTTCAAC TCACTACCAT
TCATTAGTAG AAGATTATTC TCAAAATGTT GCTGTGCGCC TAGGACATAT GGCATGCATG
GTAGAAAATG AATGTGAAGA CCCCAGCCAG GAGACTATTA CGTTCCTCTA TAAATTCATT
AAGGGAGCTT GTCCTAAAAG CTATGGCTTT AATGCAGCAA GGCTTGCTAA TCTCCCAGAG
GAAGTTATTC AAAAGGGACA TAGAAAAGCA AGAGAATTTG AGAAGATGAA TCAGTCACTA
CGATTATTTC GGGAAGTTTG CCTGGCTAGT GAAAGGTCAA CTGTAGATGC TGAAGCTGTC
CATAAATTGC TGACTTTGAT TAAGGAATTA TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu35371
Clone ID Related Accession (Same CDS sequence) XM_011532799.1
Accession Version XM_011532799.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3786bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product DNA mismatch repair protein Msh6 isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
ATGGAGGGTT ACCCCTGGTG GCCTTGTCTG GTTTACAACC ACCCCTTTGA TGGAACATTC 
ATCCGCGAGA AAGGGAAATC AGTCCGTGTT CATGTACAGT TTTTTGATGA CAGCCCAACA
AGGGGCTGGG TTAGCAAAAG GCTTTTAAAG CCATATACAG GTTCAAAATC AAAGGAAGCC
CAGAAGGGAG GTCATTTTTA CAGTGCAAAG CCTGAAATAC TGAGAGCAAT GCAACGTGCA
GATGAAGCCT TAAATAAAGA CAAGATTAAG AGGCTTGAAT TGGCAGTTTG TGATGAGCCC
TCAGAGCCAG AAGAGGAAGA AGAGATGGAG GTAGGCACAA CTTACGTAAC AGATAAGAGT
GAAGAAGATA ATGAAATTGA GAGTGAAGAG GAAGTACAGC CTAAGACACA AGGATCTAGG
CGAAGTAGCC GCCAAATAAA AAAACGAAGG GTCATATCAG ATTCTGAGAG TGACATTGGT
GGCTCTGATG TGGAATTTAA GCCAGACACT AAGGAGGAAG GAAGCAGTGA TGAAATAAGC
AGTGGAGTGG GGGATAGTGA GAGTGAAGGC CTGAACAGCC CTGTCAAAGT TGCTCGAAAG
CGGAAGAGAA TGGTGACTGG AAATGGCTCT CTTAAAAGGA AAAGCTCTAG GAAGGAAACG
CCCTCAGCCA CCAAACAAGC AACTAGCATT TCATCAGAAA CCAAGAATAC TTTGAGAGCT
TTCTCTGCCC CTCAAAATTC TGAATCCCAA GCCCACGTTA GTGGAGGTGG TGATGACAGT
AGTCGCCCTA CTGTTTGGTA TCATGAAACT TTAGAATGGC TTAAGGAGGA AAAGAGAAGA
GATGAGCACA GGAGGAGGCC TGATCACCCC GATTTTGATG CATCTACACT CTATGTGCCT
GAGGATTTCC TCAATTCTTG TACTCCTGGG ATGAGGAAGT GGTGGCAGAT TAAGTCTCAG
AACTTTGATC TTGTCATCTG TTACAAGGTG GGGAAATTTT ATGAGCTGTA CCACATGGAT
GCTCTTATTG GAGTCAGTGA ACTGGGGCTG GTATTCATGA AAGGCAACTG GGCCCATTCT
GGCTTTCCTG AAATTGCATT TGGCCGTTAT TCAGATTCCC TGGTGCAGAA GGGCTATAAA
GTAGCACGAG TGGAACAGAC TGAGACTCCA GAAATGATGG AGGCACGATG TAGAAAGATG
GCACATATAT CCAAGTATGA TAGAGTGGTG AGGAGGGAGA TCTGTAGGAT CATTACCAAG
GGTACACAGA CTTACAGTGT GCTGGAAGGT GATCCCTCTG AGAACTACAG TAAGTATCTT
CTTAGCCTCA AAGAAAAAGA GGAAGATTCT TCTGGCCATA CTCGTGCATA TGGTGTGTGC
TTTGTTGATA CTTCACTGGG AAAGTTTTTC ATAGGTCAGT TTTCAGATGA TCGCCATTGT
TCGAGATTTA GGACTCTAGT GGCACACTAT CCCCCAGTAC AAGTTTTATT TGAAAAAGGA
AATCTCTCAA AGGAAACTAA AACAATTCTA AAGAGTTCAT TGTCCTGTTC TCTTCAGGAA
GGTCTGATAC CCGGCTCCCA GTTTTGGGAT GCATCCAAAA CTTTGAGAAC TCTCCTTGAG
GAAGAATATT TTAGGGAAAA GCTAAGTGAT GGCATTGGGG TGATGTTACC CCAGGTGCTT
AAAGGTATGA CTTCAGAGTC TGATTCCATT GGGTTGACAC CAGGAGAGAA AAGTGAATTG
GCCCTCTCTG CTCTAGGTGG TTGTGTCTTC TACCTCAAAA AATGCCTTAT TGATCAGGAG
CTTTTATCAA TGGCTAATTT TGAAGAATAT ATTCCCTTGG ATTCTGACAC AGTCAGCACT
ACAAGATCTG GTGCTATCTT CACCAAAGCC TATCAACGAA TGGTGCTAGA TGCAGTGACA
TTAAACAACT TGGAGATTTT TCTGAATGGA ACAAATGGTT CTACTGAAGG AACCCTACTA
GAGAGGGTTG ATACTTGCCA TACTCCTTTT GGTAAGCGGC TCCTAAAGCA ATGGCTTTGT
GCCCCACTCT GTAACCATTA TGCTATTAAT GATCGTCTAG ATGCCATAGA AGACCTCATG
GTTGTGCCTG ACAAAATCTC CGAAGTTGTA GAGCTTCTAA AGAAGCTTCC AGATCTTGAG
AGGCTACTCA GTAAAATTCA TAATGTTGGG TCTCCCCTGA AGAGTCAGAA CCACCCAGAC
AGCAGGGCTA TAATGTATGA AGAAACTACA TACAGCAAGA AGAAGATTAT TGATTTTCTT
TCTGCTCTGG AAGGATTCAA AGTAATGTGT AAAATTATAG GGATCATGGA AGAAGTTGCT
GATGGTTTTA AGTCTAAAAT CCTTAAGCAG GTCATCTCTC TGCAGACAAA AAATCCTGAA
GGTCGTTTTC CTGATTTGAC TGTAGAATTG AACCGATGGG ATACAGCCTT TGACCATGAA
AAGGCTCGAA AGACTGGACT TATTACTCCC AAAGCAGGCT TTGACTCTGA TTATGACCAA
GCTCTTGCTG ACATAAGAGA AAATGAACAG AGCCTCCTGG AATACCTAGA GAAACAGCGC
AACAGAATTG GCTGTAGGAC CATAGTCTAT TGGGGGATTG GTAGGAACCG TTACCAGCTG
GAAATTCCTG AGAATTTCAC CACTCGCAAT TTGCCAGAAG AATACGAGTT GAAATCTACC
AAGAAGGGCT GTAAACGATA CTGGACCAAA ACTATTGAAA AGAAGTTGGC TAATCTCATA
AATGCTGAAG AACGGAGGGA TGTATCATTG AAGGACTGCA TGCGGCGACT GTTCTATAAC
TTTGATAAAA ATTACAAGGA CTGGCAGTCT GCTGTAGAGT GTATCGCAGT GTTGGATGTT
TTACTGTGCC TGGCTAACTA TAGTCGAGGG GGTGATGGTC CTATGTGTCG CCCAGTAATT
CTGTTGCCGG AAGATACCCC CCCCTTCTTA GAGCTTAAAG GATCACGCCA TCCTTGCATT
ACGAAGACTT TTTTTGGAGA TGATTTTATT CCTAATGACA TTCTAATAGG CTGTGAGGAA
GAGGAGCAGG AAAATGGCAA AGCCTATTGT GTGCTTGTTA CTGGACCAAA TATGGGGGGC
AAGTCTACGC TTATGAGACA GGCTGGCTTA TTAGCTGTAA TGGCCCAGAT GGGTTGTTAC
GTCCCTGCTG AAGTGTGCAG GCTCACACCA ATTGATAGAG TGTTTACTAG ACTTGGTGCC
TCAGACAGAA TAATGTCAGG TGAAAGTACA TTTTTTGTTG AATTAAGTGA AACTGCCAGC
ATACTCATGC ATGCAACAGC ACATTCTCTG GTGCTTGTGG ATGAATTAGG AAGAGGTACT
GCAACATTTG ATGGGACGGC AATAGCAAAT GCAGTTGTTA AAGAACTTGC TGAGACTATA
AAATGTCGTA CATTATTTTC AACTCACTAC CATTCATTAG TAGAAGATTA TTCTCAAAAT
GTTGCTGTGC GCCTAGGACA TATGGCATGC ATGGTAGAAA ATGAATGTGA AGACCCCAGC
CAGGAGACTA TTACGTTCCT CTATAAATTC ATTAAGGGAG CTTGTCCTAA AAGCTATGGC
TTTAATGCAG CAAGGCTTGC TAATCTCCCA GAGGAAGTTA TTCAAAAGGG ACATAGAAAA
GCAAGAGAAT TTGAGAAGAT GAATCAGTCA CTACGATTAT TTCGGGAAGT TTGCCTGGCT
AGTGAAAGGT CAACTGTAGA TGCTGAAGCT GTCCATAAAT TGCTGACTTT GATTAAGGAA
TTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011531101.1
CDS232..4017
Misc Feature(1)232..519
Misc Feature(2)order(232..234,241..243,250..252,331..333,343..345,349..351)
Misc Feature(3)1153..3942
Misc Feature(4)1153..1509
Misc Feature(5)1546..2010
Misc Feature(6)2149..>2415
Misc Feature(7)2728..3006
Misc Feature(8)3205..3873
Misc Feature(9)3334..3357
Misc Feature(10)order(3343..3348,3352..3360,3466..3468,3571..3576,3676..3678)
Misc Feature(11)3457..3468
Misc Feature(12)3481..3522
Misc Feature(13)3559..3576
Misc Feature(14)3583..3594
Misc Feature(15)3664..3684
Translation

Target ORF information:

RefSeq Version XM_011532799.1
Organism Homo sapiens(Human)
Definition Homo sapiens mutS homolog 6 (MSH6), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532799.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
ATGGAGGGTT ACCCCTGGTG GCCTTGTCTG GTTTACAACC ACCCCTTTGA TGGAACATTC 
ATCCGCGAGA AAGGGAAATC AGTCCGTGTT CATGTACAGT TTTTTGATGA CAGCCCAACA
AGGGGCTGGG TTAGCAAAAG GCTTTTAAAG CCATATACAG GTTCAAAATC AAAGGAAGCC
CAGAAGGGAG GTCATTTTTA CAGTGCAAAG CCTGAAATAC TGAGAGCAAT GCAACGTGCA
GATGAAGCCT TAAATAAAGA CAAGATTAAG AGGCTTGAAT TGGCAGTTTG TGATGAGCCC
TCAGAGCCAG AAGAGGAAGA AGAGATGGAG GTAGGCACAA CTTACGTAAC AGATAAGAGT
GAAGAAGATA ATGAAATTGA GAGTGAAGAG GAAGTACAGC CTAAGACACA AGGATCTAGG
CGAAGTAGCC GCCAAATAAA AAAACGAAGG GTCATATCAG ATTCTGAGAG TGACATTGGT
GGCTCTGATG TGGAATTTAA GCCAGACACT AAGGAGGAAG GAAGCAGTGA TGAAATAAGC
AGTGGAGTGG GGGATAGTGA GAGTGAAGGC CTGAACAGCC CTGTCAAAGT TGCTCGAAAG
CGGAAGAGAA TGGTGACTGG AAATGGCTCT CTTAAAAGGA AAAGCTCTAG GAAGGAAACG
CCCTCAGCCA CCAAACAAGC AACTAGCATT TCATCAGAAA CCAAGAATAC TTTGAGAGCT
TTCTCTGCCC CTCAAAATTC TGAATCCCAA GCCCACGTTA GTGGAGGTGG TGATGACAGT
AGTCGCCCTA CTGTTTGGTA TCATGAAACT TTAGAATGGC TTAAGGAGGA AAAGAGAAGA
GATGAGCACA GGAGGAGGCC TGATCACCCC GATTTTGATG CATCTACACT CTATGTGCCT
GAGGATTTCC TCAATTCTTG TACTCCTGGG ATGAGGAAGT GGTGGCAGAT TAAGTCTCAG
AACTTTGATC TTGTCATCTG TTACAAGGTG GGGAAATTTT ATGAGCTGTA CCACATGGAT
GCTCTTATTG GAGTCAGTGA ACTGGGGCTG GTATTCATGA AAGGCAACTG GGCCCATTCT
GGCTTTCCTG AAATTGCATT TGGCCGTTAT TCAGATTCCC TGGTGCAGAA GGGCTATAAA
GTAGCACGAG TGGAACAGAC TGAGACTCCA GAAATGATGG AGGCACGATG TAGAAAGATG
GCACATATAT CCAAGTATGA TAGAGTGGTG AGGAGGGAGA TCTGTAGGAT CATTACCAAG
GGTACACAGA CTTACAGTGT GCTGGAAGGT GATCCCTCTG AGAACTACAG TAAGTATCTT
CTTAGCCTCA AAGAAAAAGA GGAAGATTCT TCTGGCCATA CTCGTGCATA TGGTGTGTGC
TTTGTTGATA CTTCACTGGG AAAGTTTTTC ATAGGTCAGT TTTCAGATGA TCGCCATTGT
TCGAGATTTA GGACTCTAGT GGCACACTAT CCCCCAGTAC AAGTTTTATT TGAAAAAGGA
AATCTCTCAA AGGAAACTAA AACAATTCTA AAGAGTTCAT TGTCCTGTTC TCTTCAGGAA
GGTCTGATAC CCGGCTCCCA GTTTTGGGAT GCATCCAAAA CTTTGAGAAC TCTCCTTGAG
GAAGAATATT TTAGGGAAAA GCTAAGTGAT GGCATTGGGG TGATGTTACC CCAGGTGCTT
AAAGGTATGA CTTCAGAGTC TGATTCCATT GGGTTGACAC CAGGAGAGAA AAGTGAATTG
GCCCTCTCTG CTCTAGGTGG TTGTGTCTTC TACCTCAAAA AATGCCTTAT TGATCAGGAG
CTTTTATCAA TGGCTAATTT TGAAGAATAT ATTCCCTTGG ATTCTGACAC AGTCAGCACT
ACAAGATCTG GTGCTATCTT CACCAAAGCC TATCAACGAA TGGTGCTAGA TGCAGTGACA
TTAAACAACT TGGAGATTTT TCTGAATGGA ACAAATGGTT CTACTGAAGG AACCCTACTA
GAGAGGGTTG ATACTTGCCA TACTCCTTTT GGTAAGCGGC TCCTAAAGCA ATGGCTTTGT
GCCCCACTCT GTAACCATTA TGCTATTAAT GATCGTCTAG ATGCCATAGA AGACCTCATG
GTTGTGCCTG ACAAAATCTC CGAAGTTGTA GAGCTTCTAA AGAAGCTTCC AGATCTTGAG
AGGCTACTCA GTAAAATTCA TAATGTTGGG TCTCCCCTGA AGAGTCAGAA CCACCCAGAC
AGCAGGGCTA TAATGTATGA AGAAACTACA TACAGCAAGA AGAAGATTAT TGATTTTCTT
TCTGCTCTGG AAGGATTCAA AGTAATGTGT AAAATTATAG GGATCATGGA AGAAGTTGCT
GATGGTTTTA AGTCTAAAAT CCTTAAGCAG GTCATCTCTC TGCAGACAAA AAATCCTGAA
GGTCGTTTTC CTGATTTGAC TGTAGAATTG AACCGATGGG ATACAGCCTT TGACCATGAA
AAGGCTCGAA AGACTGGACT TATTACTCCC AAAGCAGGCT TTGACTCTGA TTATGACCAA
GCTCTTGCTG ACATAAGAGA AAATGAACAG AGCCTCCTGG AATACCTAGA GAAACAGCGC
AACAGAATTG GCTGTAGGAC CATAGTCTAT TGGGGGATTG GTAGGAACCG TTACCAGCTG
GAAATTCCTG AGAATTTCAC CACTCGCAAT TTGCCAGAAG AATACGAGTT GAAATCTACC
AAGAAGGGCT GTAAACGATA CTGGACCAAA ACTATTGAAA AGAAGTTGGC TAATCTCATA
AATGCTGAAG AACGGAGGGA TGTATCATTG AAGGACTGCA TGCGGCGACT GTTCTATAAC
TTTGATAAAA ATTACAAGGA CTGGCAGTCT GCTGTAGAGT GTATCGCAGT GTTGGATGTT
TTACTGTGCC TGGCTAACTA TAGTCGAGGG GGTGATGGTC CTATGTGTCG CCCAGTAATT
CTGTTGCCGG AAGATACCCC CCCCTTCTTA GAGCTTAAAG GATCACGCCA TCCTTGCATT
ACGAAGACTT TTTTTGGAGA TGATTTTATT CCTAATGACA TTCTAATAGG CTGTGAGGAA
GAGGAGCAGG AAAATGGCAA AGCCTATTGT GTGCTTGTTA CTGGACCAAA TATGGGGGGC
AAGTCTACGC TTATGAGACA GGCTGGCTTA TTAGCTGTAA TGGCCCAGAT GGGTTGTTAC
GTCCCTGCTG AAGTGTGCAG GCTCACACCA ATTGATAGAG TGTTTACTAG ACTTGGTGCC
TCAGACAGAA TAATGTCAGG TGAAAGTACA TTTTTTGTTG AATTAAGTGA AACTGCCAGC
ATACTCATGC ATGCAACAGC ACATTCTCTG GTGCTTGTGG ATGAATTAGG AAGAGGTACT
GCAACATTTG ATGGGACGGC AATAGCAAAT GCAGTTGTTA AAGAACTTGC TGAGACTATA
AAATGTCGTA CATTATTTTC AACTCACTAC CATTCATTAG TAGAAGATTA TTCTCAAAAT
GTTGCTGTGC GCCTAGGACA TATGGCATGC ATGGTAGAAA ATGAATGTGA AGACCCCAGC
CAGGAGACTA TTACGTTCCT CTATAAATTC ATTAAGGGAG CTTGTCCTAA AAGCTATGGC
TTTAATGCAG CAAGGCTTGC TAATCTCCCA GAGGAAGTTA TTCAAAAGGG ACATAGAAAA
GCAAGAGAAT TTGAGAAGAT GAATCAGTCA CTACGATTAT TTCGGGAAGT TTGCCTGGCT
AGTGAAAGGT CAACTGTAGA TGCTGAAGCT GTCCATAAAT TGCTGACTTT GATTAAGGAA
TTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58146
Clone ID Related Accession (Same CDS sequence) XM_011532798.1
Accession Version XM_011532798.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3900bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product DNA mismatch repair protein Msh6 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
ATGCCTGCGG GAGGCCGAAC GGGGAGAGTC CGGTGGTGTG GGGTGCGAAA GGAGGTTCCT 
CGGCCGGCGC GGAGATATTG TGACTTCTCA CCAGGAGATT TGGTTTGGGC CAAGATGGAG
GGTTACCCCT GGTGGCCTTG TCTGGTTTAC AACCACCCCT TTGATGGAAC ATTCATCCGC
GAGAAAGGGA AATCAGTCCG TGTTCATGTA CAGTTTTTTG ATGACAGCCC AACAAGGGGC
TGGGTTAGCA AAAGGCTTTT AAAGCCATAT ACAGGTTCAA AATCAAAGGA AGCCCAGAAG
GGAGGTCATT TTTACAGTGC AAAGCCTGAA ATACTGAGAG CAATGCAACG TGCAGATGAA
GCCTTAAATA AAGACAAGAT TAAGAGGCTT GAATTGGCAG TTTGTGATGA GCCCTCAGAG
CCAGAAGAGG AAGAAGAGAT GGAGGTAGGC ACAACTTACG TAACAGATAA GAGTGAAGAA
GATAATGAAA TTGAGAGTGA AGAGGAAGTA CAGCCTAAGA CACAAGGATC TAGGCGAAGT
AGCCGCCAAA TAAAAAAACG AAGGGTCATA TCAGATTCTG AGAGTGACAT TGGTGGCTCT
GATGTGGAAT TTAAGCCAGA CACTAAGGAG GAAGGAAGCA GTGATGAAAT AAGCAGTGGA
GTGGGGGATA GTGAGAGTGA AGGCCTGAAC AGCCCTGTCA AAGTTGCTCG AAAGCGGAAG
AGAATGGTGA CTGGAAATGG CTCTCTTAAA AGGAAAAGCT CTAGGAAGGA AACGCCCTCA
GCCACCAAAC AAGCAACTAG CATTTCATCA GAAACCAAGA ATACTTTGAG AGCTTTCTCT
GCCCCTCAAA ATTCTGAATC CCAAGCCCAC GTTAGTGGAG GTGGTGATGA CAGTAGTCGC
CCTACTGTTT GGTATCATGA AACTTTAGAA TGGCTTAAGG AGGAAAAGAG AAGAGATGAG
CACAGGAGGA GGCCTGATCA CCCCGATTTT GATGCATCTA CACTCTATGT GCCTGAGGAT
TTCCTCAATT CTTGTACTCC TGGGATGAGG AAGTGGTGGC AGATTAAGTC TCAGAACTTT
GATCTTGTCA TCTGTTACAA GGTGGGGAAA TTTTATGAGC TGTACCACAT GGATGCTCTT
ATTGGAGTCA GTGAACTGGG GCTGGTATTC ATGAAAGGCA ACTGGGCCCA TTCTGGCTTT
CCTGAAATTG CATTTGGCCG TTATTCAGAT TCCCTGGTGC AGAAGGGCTA TAAAGTAGCA
CGAGTGGAAC AGACTGAGAC TCCAGAAATG ATGGAGGCAC GATGTAGAAA GATGGCACAT
ATATCCAAGT ATGATAGAGT GGTGAGGAGG GAGATCTGTA GGATCATTAC CAAGGGTACA
CAGACTTACA GTGTGCTGGA AGGTGATCCC TCTGAGAACT ACAGTAAGTA TCTTCTTAGC
CTCAAAGAAA AAGAGGAAGA TTCTTCTGGC CATACTCGTG CATATGGTGT GTGCTTTGTT
GATACTTCAC TGGGAAAGTT TTTCATAGGT CAGTTTTCAG ATGATCGCCA TTGTTCGAGA
TTTAGGACTC TAGTGGCACA CTATCCCCCA GTACAAGTTT TATTTGAAAA AGGAAATCTC
TCAAAGGAAA CTAAAACAAT TCTAAAGAGT TCATTGTCCT GTTCTCTTCA GGAAGGTCTG
ATACCCGGCT CCCAGTTTTG GGATGCATCC AAAACTTTGA GAACTCTCCT TGAGGAAGAA
TATTTTAGGG AAAAGCTAAG TGATGGCATT GGGGTGATGT TACCCCAGGT GCTTAAAGGT
ATGACTTCAG AGTCTGATTC CATTGGGTTG ACACCAGGAG AGAAAAGTGA ATTGGCCCTC
TCTGCTCTAG GTGGTTGTGT CTTCTACCTC AAAAAATGCC TTATTGATCA GGAGCTTTTA
TCAATGGCTA ATTTTGAAGA ATATATTCCC TTGGATTCTG ACACAGTCAG CACTACAAGA
TCTGGTGCTA TCTTCACCAA AGCCTATCAA CGAATGGTGC TAGATGCAGT GACATTAAAC
AACTTGGAGA TTTTTCTGAA TGGAACAAAT GGTTCTACTG AAGGAACCCT ACTAGAGAGG
GTTGATACTT GCCATACTCC TTTTGGTAAG CGGCTCCTAA AGCAATGGCT TTGTGCCCCA
CTCTGTAACC ATTATGCTAT TAATGATCGT CTAGATGCCA TAGAAGACCT CATGGTTGTG
CCTGACAAAA TCTCCGAAGT TGTAGAGCTT CTAAAGAAGC TTCCAGATCT TGAGAGGCTA
CTCAGTAAAA TTCATAATGT TGGGTCTCCC CTGAAGAGTC AGAACCACCC AGACAGCAGG
GCTATAATGT ATGAAGAAAC TACATACAGC AAGAAGAAGA TTATTGATTT TCTTTCTGCT
CTGGAAGGAT TCAAAGTAAT GTGTAAAATT ATAGGGATCA TGGAAGAAGT TGCTGATGGT
TTTAAGTCTA AAATCCTTAA GCAGGTCATC TCTCTGCAGA CAAAAAATCC TGAAGGTCGT
TTTCCTGATT TGACTGTAGA ATTGAACCGA TGGGATACAG CCTTTGACCA TGAAAAGGCT
CGAAAGACTG GACTTATTAC TCCCAAAGCA GGCTTTGACT CTGATTATGA CCAAGCTCTT
GCTGACATAA GAGAAAATGA ACAGAGCCTC CTGGAATACC TAGAGAAACA GCGCAACAGA
ATTGGCTGTA GGACCATAGT CTATTGGGGG ATTGGTAGGA ACCGTTACCA GCTGGAAATT
CCTGAGAATT TCACCACTCG CAATTTGCCA GAAGAATACG AGTTGAAATC TACCAAGAAG
GGCTGTAAAC GATACTGGAC CAAAACTATT GAAAAGAAGT TGGCTAATCT CATAAATGCT
GAAGAACGGA GGGATGTATC ATTGAAGGAC TGCATGCGGC GACTGTTCTA TAACTTTGAT
AAAAATTACA AGGACTGGCA GTCTGCTGTA GAGTGTATCG CAGTGTTGGA TGTTTTACTG
TGCCTGGCTA ACTATAGTCG AGGGGGTGAT GGTCCTATGT GTCGCCCAGT AATTCTGTTG
CCGGAAGATA CCCCCCCCTT CTTAGAGCTT AAAGGATCAC GCCATCCTTG CATTACGAAG
ACTTTTTTTG GAGATGATTT TATTCCTAAT GACATTCTAA TAGGCTGTGA GGAAGAGGAG
CAGGAAAATG GCAAAGCCTA TTGTGTGCTT GTTACTGGAC CAAATATGGG GGGCAAGTCT
ACGCTTATGA GACAGGCTGG CTTATTAGCT GTAATGGCCC AGATGGGTTG TTACGTCCCT
GCTGAAGTGT GCAGGCTCAC ACCAATTGAT AGAGTGTTTA CTAGACTTGG TGCCTCAGAC
AGAATAATGT CAGGTGAAAG TACATTTTTT GTTGAATTAA GTGAAACTGC CAGCATACTC
ATGCATGCAA CAGCACATTC TCTGGTGCTT GTGGATGAAT TAGGAAGAGG TACTGCAACA
TTTGATGGGA CGGCAATAGC AAATGCAGTT GTTAAAGAAC TTGCTGAGAC TATAAAATGT
CGTACATTAT TTTCAACTCA CTACCATTCA TTAGTAGAAG ATTATTCTCA AAATGTTGCT
GTGCGCCTAG GACATATGGC ATGCATGGTA GAAAATGAAT GTGAAGACCC CAGCCAGGAG
ACTATTACGT TCCTCTATAA ATTCATTAAG GGAGCTTGTC CTAAAAGCTA TGGCTTTAAT
GCAGCAAGGC TTGCTAATCT CCCAGAGGAA GTTATTCAAA AGGGACATAG AAAAGCAAGA
GAATTTGAGA AGATGAATCA GTCACTACGA TTATTTCGGG AAGTTTGCCT GGCTAGTGAA
AGGTCAACTG TAGATGCTGA AGCTGTCCAT AAATTGCTGA CTTTGATTAA GGAATTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011531100.1
CDS43..3942
Misc Feature(1)121..444
Misc Feature(2)order(157..159,166..168,175..177,256..258,268..270,274..276)
Misc Feature(3)1078..3867
Misc Feature(4)1078..1434
Misc Feature(5)1471..1935
Misc Feature(6)2074..>2340
Misc Feature(7)2653..2931
Misc Feature(8)3130..3798
Misc Feature(9)3259..3282
Misc Feature(10)order(3268..3273,3277..3285,3391..3393,3496..3501,3601..3603)
Misc Feature(11)3382..3393
Misc Feature(12)3406..3447
Misc Feature(13)3484..3501
Misc Feature(14)3508..3519
Misc Feature(15)3589..3609
Translation

Target ORF information:

RefSeq Version XM_011532798.1
Organism Homo sapiens(Human)
Definition Homo sapiens mutS homolog 6 (MSH6), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011532798.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
ATGCCTGCGG GAGGCCGAAC GGGGAGAGTC CGGTGGTGTG GGGTGCGAAA GGAGGTTCCT 
CGGCCGGCGC GGAGATATTG TGACTTCTCA CCAGGAGATT TGGTTTGGGC CAAGATGGAG
GGTTACCCCT GGTGGCCTTG TCTGGTTTAC AACCACCCCT TTGATGGAAC ATTCATCCGC
GAGAAAGGGA AATCAGTCCG TGTTCATGTA CAGTTTTTTG ATGACAGCCC AACAAGGGGC
TGGGTTAGCA AAAGGCTTTT AAAGCCATAT ACAGGTTCAA AATCAAAGGA AGCCCAGAAG
GGAGGTCATT TTTACAGTGC AAAGCCTGAA ATACTGAGAG CAATGCAACG TGCAGATGAA
GCCTTAAATA AAGACAAGAT TAAGAGGCTT GAATTGGCAG TTTGTGATGA GCCCTCAGAG
CCAGAAGAGG AAGAAGAGAT GGAGGTAGGC ACAACTTACG TAACAGATAA GAGTGAAGAA
GATAATGAAA TTGAGAGTGA AGAGGAAGTA CAGCCTAAGA CACAAGGATC TAGGCGAAGT
AGCCGCCAAA TAAAAAAACG AAGGGTCATA TCAGATTCTG AGAGTGACAT TGGTGGCTCT
GATGTGGAAT TTAAGCCAGA CACTAAGGAG GAAGGAAGCA GTGATGAAAT AAGCAGTGGA
GTGGGGGATA GTGAGAGTGA AGGCCTGAAC AGCCCTGTCA AAGTTGCTCG AAAGCGGAAG
AGAATGGTGA CTGGAAATGG CTCTCTTAAA AGGAAAAGCT CTAGGAAGGA AACGCCCTCA
GCCACCAAAC AAGCAACTAG CATTTCATCA GAAACCAAGA ATACTTTGAG AGCTTTCTCT
GCCCCTCAAA ATTCTGAATC CCAAGCCCAC GTTAGTGGAG GTGGTGATGA CAGTAGTCGC
CCTACTGTTT GGTATCATGA AACTTTAGAA TGGCTTAAGG AGGAAAAGAG AAGAGATGAG
CACAGGAGGA GGCCTGATCA CCCCGATTTT GATGCATCTA CACTCTATGT GCCTGAGGAT
TTCCTCAATT CTTGTACTCC TGGGATGAGG AAGTGGTGGC AGATTAAGTC TCAGAACTTT
GATCTTGTCA TCTGTTACAA GGTGGGGAAA TTTTATGAGC TGTACCACAT GGATGCTCTT
ATTGGAGTCA GTGAACTGGG GCTGGTATTC ATGAAAGGCA ACTGGGCCCA TTCTGGCTTT
CCTGAAATTG CATTTGGCCG TTATTCAGAT TCCCTGGTGC AGAAGGGCTA TAAAGTAGCA
CGAGTGGAAC AGACTGAGAC TCCAGAAATG ATGGAGGCAC GATGTAGAAA GATGGCACAT
ATATCCAAGT ATGATAGAGT GGTGAGGAGG GAGATCTGTA GGATCATTAC CAAGGGTACA
CAGACTTACA GTGTGCTGGA AGGTGATCCC TCTGAGAACT ACAGTAAGTA TCTTCTTAGC
CTCAAAGAAA AAGAGGAAGA TTCTTCTGGC CATACTCGTG CATATGGTGT GTGCTTTGTT
GATACTTCAC TGGGAAAGTT TTTCATAGGT CAGTTTTCAG ATGATCGCCA TTGTTCGAGA
TTTAGGACTC TAGTGGCACA CTATCCCCCA GTACAAGTTT TATTTGAAAA AGGAAATCTC
TCAAAGGAAA CTAAAACAAT TCTAAAGAGT TCATTGTCCT GTTCTCTTCA GGAAGGTCTG
ATACCCGGCT CCCAGTTTTG GGATGCATCC AAAACTTTGA GAACTCTCCT TGAGGAAGAA
TATTTTAGGG AAAAGCTAAG TGATGGCATT GGGGTGATGT TACCCCAGGT GCTTAAAGGT
ATGACTTCAG AGTCTGATTC CATTGGGTTG ACACCAGGAG AGAAAAGTGA ATTGGCCCTC
TCTGCTCTAG GTGGTTGTGT CTTCTACCTC AAAAAATGCC TTATTGATCA GGAGCTTTTA
TCAATGGCTA ATTTTGAAGA ATATATTCCC TTGGATTCTG ACACAGTCAG CACTACAAGA
TCTGGTGCTA TCTTCACCAA AGCCTATCAA CGAATGGTGC TAGATGCAGT GACATTAAAC
AACTTGGAGA TTTTTCTGAA TGGAACAAAT GGTTCTACTG AAGGAACCCT ACTAGAGAGG
GTTGATACTT GCCATACTCC TTTTGGTAAG CGGCTCCTAA AGCAATGGCT TTGTGCCCCA
CTCTGTAACC ATTATGCTAT TAATGATCGT CTAGATGCCA TAGAAGACCT CATGGTTGTG
CCTGACAAAA TCTCCGAAGT TGTAGAGCTT CTAAAGAAGC TTCCAGATCT TGAGAGGCTA
CTCAGTAAAA TTCATAATGT TGGGTCTCCC CTGAAGAGTC AGAACCACCC AGACAGCAGG
GCTATAATGT ATGAAGAAAC TACATACAGC AAGAAGAAGA TTATTGATTT TCTTTCTGCT
CTGGAAGGAT TCAAAGTAAT GTGTAAAATT ATAGGGATCA TGGAAGAAGT TGCTGATGGT
TTTAAGTCTA AAATCCTTAA GCAGGTCATC TCTCTGCAGA CAAAAAATCC TGAAGGTCGT
TTTCCTGATT TGACTGTAGA ATTGAACCGA TGGGATACAG CCTTTGACCA TGAAAAGGCT
CGAAAGACTG GACTTATTAC TCCCAAAGCA GGCTTTGACT CTGATTATGA CCAAGCTCTT
GCTGACATAA GAGAAAATGA ACAGAGCCTC CTGGAATACC TAGAGAAACA GCGCAACAGA
ATTGGCTGTA GGACCATAGT CTATTGGGGG ATTGGTAGGA ACCGTTACCA GCTGGAAATT
CCTGAGAATT TCACCACTCG CAATTTGCCA GAAGAATACG AGTTGAAATC TACCAAGAAG
GGCTGTAAAC GATACTGGAC CAAAACTATT GAAAAGAAGT TGGCTAATCT CATAAATGCT
GAAGAACGGA GGGATGTATC ATTGAAGGAC TGCATGCGGC GACTGTTCTA TAACTTTGAT
AAAAATTACA AGGACTGGCA GTCTGCTGTA GAGTGTATCG CAGTGTTGGA TGTTTTACTG
TGCCTGGCTA ACTATAGTCG AGGGGGTGAT GGTCCTATGT GTCGCCCAGT AATTCTGTTG
CCGGAAGATA CCCCCCCCTT CTTAGAGCTT AAAGGATCAC GCCATCCTTG CATTACGAAG
ACTTTTTTTG GAGATGATTT TATTCCTAAT GACATTCTAA TAGGCTGTGA GGAAGAGGAG
CAGGAAAATG GCAAAGCCTA TTGTGTGCTT GTTACTGGAC CAAATATGGG GGGCAAGTCT
ACGCTTATGA GACAGGCTGG CTTATTAGCT GTAATGGCCC AGATGGGTTG TTACGTCCCT
GCTGAAGTGT GCAGGCTCAC ACCAATTGAT AGAGTGTTTA CTAGACTTGG TGCCTCAGAC
AGAATAATGT CAGGTGAAAG TACATTTTTT GTTGAATTAA GTGAAACTGC CAGCATACTC
ATGCATGCAA CAGCACATTC TCTGGTGCTT GTGGATGAAT TAGGAAGAGG TACTGCAACA
TTTGATGGGA CGGCAATAGC AAATGCAGTT GTTAAAGAAC TTGCTGAGAC TATAAAATGT
CGTACATTAT TTTCAACTCA CTACCATTCA TTAGTAGAAG ATTATTCTCA AAATGTTGCT
GTGCGCCTAG GACATATGGC ATGCATGGTA GAAAATGAAT GTGAAGACCC CAGCCAGGAG
ACTATTACGT TCCTCTATAA ATTCATTAAG GGAGCTTGTC CTAAAAGCTA TGGCTTTAAT
GCAGCAAGGC TTGCTAATCT CCCAGAGGAA GTTATTCAAA AGGGACATAG AAAAGCAAGA
GAATTTGAGA AGATGAATCA GTCACTACGA TTATTTCGGG AAGTTTGCCT GGCTAGTGAA
AGGTCAACTG TAGATGCTGA AGCTGTCCAT AAATTGCTGA CTTTGATTAA GGAATTATAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25314
Clone ID Related Accession (Same CDS sequence) NM_000179.2
Accession Version NM_000179.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 4083bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-30
Organism Homo sapiens(Human)
Product DNA mismatch repair protein Msh6 isoform 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC071594.1, DA857066.1, U28946.1 and BC104665.1. This sequence is a reference standard in the RefSeqGene project. On Sep 22, 2007 this sequence version replaced NM_000179.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U28946.1, SRR1803616.101095.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
ATGTCGCGAC AGAGCACCCT GTACAGCTTC TTCCCCAAGT CTCCGGCGCT GAGTGATGCC 
AACAAGGCCT CGGCCAGGGC CTCACGCGAA GGCGGCCGTG CCGCCGCTGC CCCCGGGGCC
TCTCCTTCCC CAGGCGGGGA TGCGGCCTGG AGCGAGGCTG GGCCTGGGCC CAGGCCCTTG
GCGCGCTCCG CGTCACCGCC CAAGGCGAAG AACCTCAACG GAGGGCTGCG GAGATCGGTA
GCGCCTGCTG CCCCCACCAG TTGTGACTTC TCACCAGGAG ATTTGGTTTG GGCCAAGATG
GAGGGTTACC CCTGGTGGCC TTGTCTGGTT TACAACCACC CCTTTGATGG AACATTCATC
CGCGAGAAAG GGAAATCAGT CCGTGTTCAT GTACAGTTTT TTGATGACAG CCCAACAAGG
GGCTGGGTTA GCAAAAGGCT TTTAAAGCCA TATACAGGTT CAAAATCAAA GGAAGCCCAG
AAGGGAGGTC ATTTTTACAG TGCAAAGCCT GAAATACTGA GAGCAATGCA ACGTGCAGAT
GAAGCCTTAA ATAAAGACAA GATTAAGAGG CTTGAATTGG CAGTTTGTGA TGAGCCCTCA
GAGCCAGAAG AGGAAGAAGA GATGGAGGTA GGCACAACTT ACGTAACAGA TAAGAGTGAA
GAAGATAATG AAATTGAGAG TGAAGAGGAA GTACAGCCTA AGACACAAGG ATCTAGGCGA
AGTAGCCGCC AAATAAAAAA ACGAAGGGTC ATATCAGATT CTGAGAGTGA CATTGGTGGC
TCTGATGTGG AATTTAAGCC AGACACTAAG GAGGAAGGAA GCAGTGATGA AATAAGCAGT
GGAGTGGGGG ATAGTGAGAG TGAAGGCCTG AACAGCCCTG TCAAAGTTGC TCGAAAGCGG
AAGAGAATGG TGACTGGAAA TGGCTCTCTT AAAAGGAAAA GCTCTAGGAA GGAAACGCCC
TCAGCCACCA AACAAGCAAC TAGCATTTCA TCAGAAACCA AGAATACTTT GAGAGCTTTC
TCTGCCCCTC AAAATTCTGA ATCCCAAGCC CACGTTAGTG GAGGTGGTGA TGACAGTAGT
CGCCCTACTG TTTGGTATCA TGAAACTTTA GAATGGCTTA AGGAGGAAAA GAGAAGAGAT
GAGCACAGGA GGAGGCCTGA TCACCCCGAT TTTGATGCAT CTACACTCTA TGTGCCTGAG
GATTTCCTCA ATTCTTGTAC TCCTGGGATG AGGAAGTGGT GGCAGATTAA GTCTCAGAAC
TTTGATCTTG TCATCTGTTA CAAGGTGGGG AAATTTTATG AGCTGTACCA CATGGATGCT
CTTATTGGAG TCAGTGAACT GGGGCTGGTA TTCATGAAAG GCAACTGGGC CCATTCTGGC
TTTCCTGAAA TTGCATTTGG CCGTTATTCA GATTCCCTGG TGCAGAAGGG CTATAAAGTA
GCACGAGTGG AACAGACTGA GACTCCAGAA ATGATGGAGG CACGATGTAG AAAGATGGCA
CATATATCCA AGTATGATAG AGTGGTGAGG AGGGAGATCT GTAGGATCAT TACCAAGGGT
ACACAGACTT ACAGTGTGCT GGAAGGTGAT CCCTCTGAGA ACTACAGTAA GTATCTTCTT
AGCCTCAAAG AAAAAGAGGA AGATTCTTCT GGCCATACTC GTGCATATGG TGTGTGCTTT
GTTGATACTT CACTGGGAAA GTTTTTCATA GGTCAGTTTT CAGATGATCG CCATTGTTCG
AGATTTAGGA CTCTAGTGGC ACACTATCCC CCAGTACAAG TTTTATTTGA AAAAGGAAAT
CTCTCAAAGG AAACTAAAAC AATTCTAAAG AGTTCATTGT CCTGTTCTCT TCAGGAAGGT
CTGATACCCG GCTCCCAGTT TTGGGATGCA TCCAAAACTT TGAGAACTCT CCTTGAGGAA
GAATATTTTA GGGAAAAGCT AAGTGATGGC ATTGGGGTGA TGTTACCCCA GGTGCTTAAA
GGTATGACTT CAGAGTCTGA TTCCATTGGG TTGACACCAG GAGAGAAAAG TGAATTGGCC
CTCTCTGCTC TAGGTGGTTG TGTCTTCTAC CTCAAAAAAT GCCTTATTGA TCAGGAGCTT
TTATCAATGG CTAATTTTGA AGAATATATT CCCTTGGATT CTGACACAGT CAGCACTACA
AGATCTGGTG CTATCTTCAC CAAAGCCTAT CAACGAATGG TGCTAGATGC AGTGACATTA
AACAACTTGG AGATTTTTCT GAATGGAACA AATGGTTCTA CTGAAGGAAC CCTACTAGAG
AGGGTTGATA CTTGCCATAC TCCTTTTGGT AAGCGGCTCC TAAAGCAATG GCTTTGTGCC
CCACTCTGTA ACCATTATGC TATTAATGAT CGTCTAGATG CCATAGAAGA CCTCATGGTT
GTGCCTGACA AAATCTCCGA AGTTGTAGAG CTTCTAAAGA AGCTTCCAGA TCTTGAGAGG
CTACTCAGTA AAATTCATAA TGTTGGGTCT CCCCTGAAGA GTCAGAACCA CCCAGACAGC
AGGGCTATAA TGTATGAAGA AACTACATAC AGCAAGAAGA AGATTATTGA TTTTCTTTCT
GCTCTGGAAG GATTCAAAGT AATGTGTAAA ATTATAGGGA TCATGGAAGA AGTTGCTGAT
GGTTTTAAGT CTAAAATCCT TAAGCAGGTC ATCTCTCTGC AGACAAAAAA TCCTGAAGGT
CGTTTTCCTG ATTTGACTGT AGAATTGAAC CGATGGGATA CAGCCTTTGA CCATGAAAAG
GCTCGAAAGA CTGGACTTAT TACTCCCAAA GCAGGCTTTG ACTCTGATTA TGACCAAGCT
CTTGCTGACA TAAGAGAAAA TGAACAGAGC CTCCTGGAAT ACCTAGAGAA ACAGCGCAAC
AGAATTGGCT GTAGGACCAT AGTCTATTGG GGGATTGGTA GGAACCGTTA CCAGCTGGAA
ATTCCTGAGA ATTTCACCAC TCGCAATTTG CCAGAAGAAT ACGAGTTGAA ATCTACCAAG
AAGGGCTGTA AACGATACTG GACCAAAACT ATTGAAAAGA AGTTGGCTAA TCTCATAAAT
GCTGAAGAAC GGAGGGATGT ATCATTGAAG GACTGCATGC GGCGACTGTT CTATAACTTT
GATAAAAATT ACAAGGACTG GCAGTCTGCT GTAGAGTGTA TCGCAGTGTT GGATGTTTTA
CTGTGCCTGG CTAACTATAG TCGAGGGGGT GATGGTCCTA TGTGTCGCCC AGTAATTCTG
TTGCCGGAAG ATACCCCCCC CTTCTTAGAG CTTAAAGGAT CACGCCATCC TTGCATTACG
AAGACTTTTT TTGGAGATGA TTTTATTCCT AATGACATTC TAATAGGCTG TGAGGAAGAG
GAGCAGGAAA ATGGCAAAGC CTATTGTGTG CTTGTTACTG GACCAAATAT GGGGGGCAAG
TCTACGCTTA TGAGACAGGC TGGCTTATTA GCTGTAATGG CCCAGATGGG TTGTTACGTC
CCTGCTGAAG TGTGCAGGCT CACACCAATT GATAGAGTGT TTACTAGACT TGGTGCCTCA
GACAGAATAA TGTCAGGTGA AAGTACATTT TTTGTTGAAT TAAGTGAAAC TGCCAGCATA
CTCATGCATG CAACAGCACA TTCTCTGGTG CTTGTGGATG AATTAGGAAG AGGTACTGCA
ACATTTGATG GGACGGCAAT AGCAAATGCA GTTGTTAAAG AACTTGCTGA GACTATAAAA
TGTCGTACAT TATTTTCAAC TCACTACCAT TCATTAGTAG AAGATTATTC TCAAAATGTT
GCTGTGCGCC TAGGACATAT GGCATGCATG GTAGAAAATG AATGTGAAGA CCCCAGCCAG
GAGACTATTA CGTTCCTCTA TAAATTCATT AAGGGAGCTT GTCCTAAAAG CTATGGCTTT
AATGCAGCAA GGCTTGCTAA TCTCCCAGAG GAAGTTATTC AAAAGGGACA TAGAAAAGCA
AGAGAATTTG AGAAGATGAA TCAGTCACTA CGATTATTTC GGGAAGTTTG CCTGGCTAGT
GAAAGGTCAA CTGTAGATGC TGAAGCTGTC CATAAATTGC TGACTTTGAT TAAGGAATTA
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_000170.1
CDS153..4235
Misc Feature(1)15..17
Misc Feature(2)192..194
Misc Feature(3)273..275
Misc Feature(4)279..281
Misc Feature(5)360..362
Misc Feature(6)387..389
Misc Feature(7)414..737
Misc Feature(8)423..425
Misc Feature(9)order(450..452,459..461,468..470,549..551,561..563,567..569)
Misc Feature(10)561..563
Misc Feature(11)561..563
Misc Feature(12)561..563
Misc Feature(13)567..569
Misc Feature(14)582..584
Misc Feature(15)750..752
Misc Feature(16)807..809
Misc Feature(17)807..809
Misc Feature(18)831..833
Misc Feature(19)831..833
Misc Feature(20)906..908
Misc Feature(21)906..908
Misc Feature(22)912..914
Misc Feature(23)912..914
Misc Feature(24)918..920
Misc Feature(25)918..920
Misc Feature(26)933..935
Misc Feature(27)933..935
Misc Feature(28)957..959
Misc Feature(29)972..974
Misc Feature(30)975..977
Misc Feature(31)987..989
Misc Feature(32)990..992
Misc Feature(33)1077..1079
Misc Feature(34)1194..1196
Misc Feature(35)1371..4160
Misc Feature(36)1371..1727
Misc Feature(37)1614..1616
Misc Feature(38)1662..1664
Misc Feature(39)1764..2228
Misc Feature(40)2367..>2633
Misc Feature(41)2640..2642
Misc Feature(42)2640..2642
Misc Feature(43)2922..2924
Misc Feature(44)2946..3224
Misc Feature(45)2955..2957
Misc Feature(46)3180..3182
Misc Feature(47)3423..4091
Misc Feature(48)3552..3575
Misc Feature(49)order(3561..3566,3570..3578,3684..3686,3789..3794,3894..3896)
Misc Feature(50)3675..3686
Misc Feature(51)3699..3740
Misc Feature(52)3777..3794
Misc Feature(53)3801..3812
Misc Feature(54)3882..3902
Exon (1)1..412
Exon (2)413..609
Exon (3)610..779
Exon (4)780..3324
Exon (5)3325..3590
Exon (6)3591..3708
Exon (7)3709..3798
Exon (8)3799..3953
Exon (9)3954..4153
Exon (10)4154..4328
Translation

Target ORF information:

RefSeq Version NM_000179.2
Organism Homo sapiens(Human)
Definition Homo sapiens mutS homolog 6 (MSH6), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_000179.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
ATGTCGCGAC AGAGCACCCT GTACAGCTTC TTCCCCAAGT CTCCGGCGCT GAGTGATGCC 
AACAAGGCCT CGGCCAGGGC CTCACGCGAA GGCGGCCGTG CCGCCGCTGC CCCCGGGGCC
TCTCCTTCCC CAGGCGGGGA TGCGGCCTGG AGCGAGGCTG GGCCTGGGCC CAGGCCCTTG
GCGCGCTCCG CGTCACCGCC CAAGGCGAAG AACCTCAACG GAGGGCTGCG GAGATCGGTA
GCGCCTGCTG CCCCCACCAG TTGTGACTTC TCACCAGGAG ATTTGGTTTG GGCCAAGATG
GAGGGTTACC CCTGGTGGCC TTGTCTGGTT TACAACCACC CCTTTGATGG AACATTCATC
CGCGAGAAAG GGAAATCAGT CCGTGTTCAT GTACAGTTTT TTGATGACAG CCCAACAAGG
GGCTGGGTTA GCAAAAGGCT TTTAAAGCCA TATACAGGTT CAAAATCAAA GGAAGCCCAG
AAGGGAGGTC ATTTTTACAG TGCAAAGCCT GAAATACTGA GAGCAATGCA ACGTGCAGAT
GAAGCCTTAA ATAAAGACAA GATTAAGAGG CTTGAATTGG CAGTTTGTGA TGAGCCCTCA
GAGCCAGAAG AGGAAGAAGA GATGGAGGTA GGCACAACTT ACGTAACAGA TAAGAGTGAA
GAAGATAATG AAATTGAGAG TGAAGAGGAA GTACAGCCTA AGACACAAGG ATCTAGGCGA
AGTAGCCGCC AAATAAAAAA ACGAAGGGTC ATATCAGATT CTGAGAGTGA CATTGGTGGC
TCTGATGTGG AATTTAAGCC AGACACTAAG GAGGAAGGAA GCAGTGATGA AATAAGCAGT
GGAGTGGGGG ATAGTGAGAG TGAAGGCCTG AACAGCCCTG TCAAAGTTGC TCGAAAGCGG
AAGAGAATGG TGACTGGAAA TGGCTCTCTT AAAAGGAAAA GCTCTAGGAA GGAAACGCCC
TCAGCCACCA AACAAGCAAC TAGCATTTCA TCAGAAACCA AGAATACTTT GAGAGCTTTC
TCTGCCCCTC AAAATTCTGA ATCCCAAGCC CACGTTAGTG GAGGTGGTGA TGACAGTAGT
CGCCCTACTG TTTGGTATCA TGAAACTTTA GAATGGCTTA AGGAGGAAAA GAGAAGAGAT
GAGCACAGGA GGAGGCCTGA TCACCCCGAT TTTGATGCAT CTACACTCTA TGTGCCTGAG
GATTTCCTCA ATTCTTGTAC TCCTGGGATG AGGAAGTGGT GGCAGATTAA GTCTCAGAAC
TTTGATCTTG TCATCTGTTA CAAGGTGGGG AAATTTTATG AGCTGTACCA CATGGATGCT
CTTATTGGAG TCAGTGAACT GGGGCTGGTA TTCATGAAAG GCAACTGGGC CCATTCTGGC
TTTCCTGAAA TTGCATTTGG CCGTTATTCA GATTCCCTGG TGCAGAAGGG CTATAAAGTA
GCACGAGTGG AACAGACTGA GACTCCAGAA ATGATGGAGG CACGATGTAG AAAGATGGCA
CATATATCCA AGTATGATAG AGTGGTGAGG AGGGAGATCT GTAGGATCAT TACCAAGGGT
ACACAGACTT ACAGTGTGCT GGAAGGTGAT CCCTCTGAGA ACTACAGTAA GTATCTTCTT
AGCCTCAAAG AAAAAGAGGA AGATTCTTCT GGCCATACTC GTGCATATGG TGTGTGCTTT
GTTGATACTT CACTGGGAAA GTTTTTCATA GGTCAGTTTT CAGATGATCG CCATTGTTCG
AGATTTAGGA CTCTAGTGGC ACACTATCCC CCAGTACAAG TTTTATTTGA AAAAGGAAAT
CTCTCAAAGG AAACTAAAAC AATTCTAAAG AGTTCATTGT CCTGTTCTCT TCAGGAAGGT
CTGATACCCG GCTCCCAGTT TTGGGATGCA TCCAAAACTT TGAGAACTCT CCTTGAGGAA
GAATATTTTA GGGAAAAGCT AAGTGATGGC ATTGGGGTGA TGTTACCCCA GGTGCTTAAA
GGTATGACTT CAGAGTCTGA TTCCATTGGG TTGACACCAG GAGAGAAAAG TGAATTGGCC
CTCTCTGCTC TAGGTGGTTG TGTCTTCTAC CTCAAAAAAT GCCTTATTGA TCAGGAGCTT
TTATCAATGG CTAATTTTGA AGAATATATT CCCTTGGATT CTGACACAGT CAGCACTACA
AGATCTGGTG CTATCTTCAC CAAAGCCTAT CAACGAATGG TGCTAGATGC AGTGACATTA
AACAACTTGG AGATTTTTCT GAATGGAACA AATGGTTCTA CTGAAGGAAC CCTACTAGAG
AGGGTTGATA CTTGCCATAC TCCTTTTGGT AAGCGGCTCC TAAAGCAATG GCTTTGTGCC
CCACTCTGTA ACCATTATGC TATTAATGAT CGTCTAGATG CCATAGAAGA CCTCATGGTT
GTGCCTGACA AAATCTCCGA AGTTGTAGAG CTTCTAAAGA AGCTTCCAGA TCTTGAGAGG
CTACTCAGTA AAATTCATAA TGTTGGGTCT CCCCTGAAGA GTCAGAACCA CCCAGACAGC
AGGGCTATAA TGTATGAAGA AACTACATAC AGCAAGAAGA AGATTATTGA TTTTCTTTCT
GCTCTGGAAG GATTCAAAGT AATGTGTAAA ATTATAGGGA TCATGGAAGA AGTTGCTGAT
GGTTTTAAGT CTAAAATCCT TAAGCAGGTC ATCTCTCTGC AGACAAAAAA TCCTGAAGGT
CGTTTTCCTG ATTTGACTGT AGAATTGAAC CGATGGGATA CAGCCTTTGA CCATGAAAAG
GCTCGAAAGA CTGGACTTAT TACTCCCAAA GCAGGCTTTG ACTCTGATTA TGACCAAGCT
CTTGCTGACA TAAGAGAAAA TGAACAGAGC CTCCTGGAAT ACCTAGAGAA ACAGCGCAAC
AGAATTGGCT GTAGGACCAT AGTCTATTGG GGGATTGGTA GGAACCGTTA CCAGCTGGAA
ATTCCTGAGA ATTTCACCAC TCGCAATTTG CCAGAAGAAT ACGAGTTGAA ATCTACCAAG
AAGGGCTGTA AACGATACTG GACCAAAACT ATTGAAAAGA AGTTGGCTAA TCTCATAAAT
GCTGAAGAAC GGAGGGATGT ATCATTGAAG GACTGCATGC GGCGACTGTT CTATAACTTT
GATAAAAATT ACAAGGACTG GCAGTCTGCT GTAGAGTGTA TCGCAGTGTT GGATGTTTTA
CTGTGCCTGG CTAACTATAG TCGAGGGGGT GATGGTCCTA TGTGTCGCCC AGTAATTCTG
TTGCCGGAAG ATACCCCCCC CTTCTTAGAG CTTAAAGGAT CACGCCATCC TTGCATTACG
AAGACTTTTT TTGGAGATGA TTTTATTCCT AATGACATTC TAATAGGCTG TGAGGAAGAG
GAGCAGGAAA ATGGCAAAGC CTATTGTGTG CTTGTTACTG GACCAAATAT GGGGGGCAAG
TCTACGCTTA TGAGACAGGC TGGCTTATTA GCTGTAATGG CCCAGATGGG TTGTTACGTC
CCTGCTGAAG TGTGCAGGCT CACACCAATT GATAGAGTGT TTACTAGACT TGGTGCCTCA
GACAGAATAA TGTCAGGTGA AAGTACATTT TTTGTTGAAT TAAGTGAAAC TGCCAGCATA
CTCATGCATG CAACAGCACA TTCTCTGGTG CTTGTGGATG AATTAGGAAG AGGTACTGCA
ACATTTGATG GGACGGCAAT AGCAAATGCA GTTGTTAAAG AACTTGCTGA GACTATAAAA
TGTCGTACAT TATTTTCAAC TCACTACCAT TCATTAGTAG AAGATTATTC TCAAAATGTT
GCTGTGCGCC TAGGACATAT GGCATGCATG GTAGAAAATG AATGTGAAGA CCCCAGCCAG
GAGACTATTA CGTTCCTCTA TAAATTCATT AAGGGAGCTT GTCCTAAAAG CTATGGCTTT
AATGCAGCAA GGCTTGCTAA TCTCCCAGAG GAAGTTATTC AAAAGGGACA TAGAAAAGCA
AGAGAATTTG AGAAGATGAA TCAGTCACTA CGATTATTTC GGGAAGTTTG CCTGGCTAGT
GAAAGGTCAA CTGTAGATGC TGAAGCTGTC CATAAATTGC TGACTTTGAT TAAGGAATTA
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology43(2)311-321(2017 Feb)
Ghanipour L,Jirström K,Sundström M,Glimelius B,Birgisson H


book

WT1, MSH6, GATA5 and PAX5 as epigenetic oral squamous cell carcinoma biomarkers - a short report.
Cellular oncology (Dordrecht)39(6)573-582(2016 Dec)
Ribeiro IP,Caramelo F,Marques F,Domingues A,Mesquita M,Barroso L,Prazeres H,Julião MJ,Baptista IP,Ferreira A,Melo JB,Carreira IM


book

Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population.
Oncology reports36(5)2823-2835(2016 Nov)
Lagerstedt-Robinson K,Rohlin A,Aravidis C,Melin B,Nordling M,Stenmark-Askmalm M,Lindblom A,Nilbert M


book

HMSH2 and HMSH6 gene expression profiles in colorectal adenocarcinoma in patients up to 50 years of age.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie83602-606(2016 Oct)
Germini D,Gehrke F,Lira D,Alves B,Azzalis L,Perez M,Fonseca F,Waisberg J


 
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