HMGCL cDNA ORF clone, Homo sapiens(human)

  • Gene

  • Clones

  • gRNAs

The following HMGCL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HMGCL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu22369 NM_000191.3
Latest version!
Homo sapiens 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$99.50-$139.30
$199.00
OHu24855 NM_001166059.1
Latest version!
Homo sapiens 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $188.30
$269.00
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OHu22369 NM_000191.2 Homo sapiens 3-hydroxymethyl-3-methylglutaryl-CoA lyase (HMGCL), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $139.30
$199.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu22369
    Clone ID Related Accession (Same CDS sequence) NM_000191.2 , NM_000191.3
    Accession Version NM_000191.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 978bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2020-01-01
    Organism Homo sapiens(human)
    Product hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590728.26, AL031295.1 and AI202943.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000191.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.750542.1, SRR5189652.81976.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta MANE Ensembl match :: ENST00000374490.8/ ENSP00000363614.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCAGCAA TGAGGAAGGC GCTTCCGCGG CGACTGGTGG GCTTGGCGTC CCTCCGGGCT 
    GTCAGCACCT CATCTATGGG CACTTTACCA AAGCGGGTGA AAATTGTGGA AGTTGGTCCC
    CGAGATGGAC TACAAAATGA AAAGAATATC GTATCTACTC CAGTGAAAAT CAAGCTGATA
    GACATGCTTT CTGAAGCAGG ACTCTCTGTT ATAGAAACCA CCAGCTTTGT GTCTCCTAAG
    TGGGTTCCCC AGATGGGTGA CCACACTGAA GTCTTGAAGG GCATTCAGAA GTTTCCTGGC
    ATCAACTACC CAGTCCTGAC CCCAAATTTG AAAGGCTTCG AGGCAGCGGT TGCTGCTGGA
    GCCAAGGAAG TAGTCATCTT TGGAGCTGCC TCAGAGCTCT TCACCAAGAA GAACATCAAT
    TGTTCCATAG AGGAGAGTTT TCAGAGGTTT GACGCAATCC TGAAGGCAGC GCAGTCAGCC
    AATATTTCTG TGCGGGGGTA CGTCTCCTGT GCTCTTGGCT GCCCTTATGA AGGGAAGATC
    TCCCCAGCTA AAGTAGCTGA GGTCACCAAG AAGTTCTACT CAATGGGCTG CTACGAGATC
    TCCCTGGGGG ACACCATTGG TGTGGGCACC CCAGGGATCA TGAAAGACAT GCTATCTGCT
    GTCATGCAGG AAGTGCCTCT GGCTGCCCTG GCTGTCCACT GCCATGACAC CTATGGTCAA
    GCCCTGGCCA ACACCTTGAT GGCCCTGCAG ATGGGAGTGA GTGTCGTGGA CTCTTCTGTG
    GCAGGACTTG GAGGCTGTCC CTACGCACAG GGGGCATCAG GAAACTTGGC CACAGAAGAC
    CTGGTCTACA TGCTAGAGGG CTTGGGCATT CACACGGGTG TGAATCTCCA GAAGCTTCTG
    GAAGCTGGAA ACTTTATCTG TCAAGCCCTG AACAGAAAAA CTAGCTCCAA AGTGGCTCAG
    GCTACCTGTA AACTCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_000182.2
    CDS15..992
    Translation

    Target ORF information:

    RefSeq Version NM_000191.3
    Organism Homo sapiens(human)
    Definition Homo sapiens 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_000191.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCAGCAA TGAGGAAGGC GCTTCCGCGG CGACTGGTGG GCTTGGCGTC CCTCCGGGCT 
    GTCAGCACCT CATCTATGGG CACTTTACCA AAGCGGGTGA AAATTGTGGA AGTTGGTCCC
    CGAGATGGAC TACAAAATGA AAAGAATATC GTATCTACTC CAGTGAAAAT CAAGCTGATA
    GACATGCTTT CTGAAGCAGG ACTCTCTGTT ATAGAAACCA CCAGCTTTGT GTCTCCTAAG
    TGGGTTCCCC AGATGGGTGA CCACACTGAA GTCTTGAAGG GCATTCAGAA GTTTCCTGGC
    ATCAACTACC CAGTCCTGAC CCCAAATTTG AAAGGCTTCG AGGCAGCGGT TGCTGCTGGA
    GCCAAGGAAG TAGTCATCTT TGGAGCTGCC TCAGAGCTCT TCACCAAGAA GAACATCAAT
    TGTTCCATAG AGGAGAGTTT TCAGAGGTTT GACGCAATCC TGAAGGCAGC GCAGTCAGCC
    AATATTTCTG TGCGGGGGTA CGTCTCCTGT GCTCTTGGCT GCCCTTATGA AGGGAAGATC
    TCCCCAGCTA AAGTAGCTGA GGTCACCAAG AAGTTCTACT CAATGGGCTG CTACGAGATC
    TCCCTGGGGG ACACCATTGG TGTGGGCACC CCAGGGATCA TGAAAGACAT GCTATCTGCT
    GTCATGCAGG AAGTGCCTCT GGCTGCCCTG GCTGTCCACT GCCATGACAC CTATGGTCAA
    GCCCTGGCCA ACACCTTGAT GGCCCTGCAG ATGGGAGTGA GTGTCGTGGA CTCTTCTGTG
    GCAGGACTTG GAGGCTGTCC CTACGCACAG GGGGCATCAG GAAACTTGGC CACAGAAGAC
    CTGGTCTACA TGCTAGAGGG CTTGGGCATT CACACGGGTG TGAATCTCCA GAAGCTTCTG
    GAAGCTGGAA ACTTTATCTG TCAAGCCCTG AACAGAAAAA CTAGCTCCAA AGTGGCTCAG
    GCTACCTGTA AACTCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu22369
    Clone ID Related Accession (Same CDS sequence) NM_000191.2 , NM_000191.3
    Accession Version NM_000191.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 978bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-12-26
    Organism Homo sapiens(human)
    Product hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 1 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590728.26, AL031295.1 and AI202943.1. This sequence is a reference standard in the RefSeqGene project. On Apr 5, 2005 this sequence version replaced NM_000191.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.215326.1, SRR1163658.147548.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCAGCAA TGAGGAAGGC GCTTCCGCGG CGACTGGTGG GCTTGGCGTC CCTCCGGGCT 
    GTCAGCACCT CATCTATGGG CACTTTACCA AAGCGGGTGA AAATTGTGGA AGTTGGTCCC
    CGAGATGGAC TACAAAATGA AAAGAATATC GTATCTACTC CAGTGAAAAT CAAGCTGATA
    GACATGCTTT CTGAAGCAGG ACTCTCTGTT ATAGAAACCA CCAGCTTTGT GTCTCCTAAG
    TGGGTTCCCC AGATGGGTGA CCACACTGAA GTCTTGAAGG GCATTCAGAA GTTTCCTGGC
    ATCAACTACC CAGTCCTGAC CCCAAATTTG AAAGGCTTCG AGGCAGCGGT TGCTGCTGGA
    GCCAAGGAAG TAGTCATCTT TGGAGCTGCC TCAGAGCTCT TCACCAAGAA GAACATCAAT
    TGTTCCATAG AGGAGAGTTT TCAGAGGTTT GACGCAATCC TGAAGGCAGC GCAGTCAGCC
    AATATTTCTG TGCGGGGGTA CGTCTCCTGT GCTCTTGGCT GCCCTTATGA AGGGAAGATC
    TCCCCAGCTA AAGTAGCTGA GGTCACCAAG AAGTTCTACT CAATGGGCTG CTACGAGATC
    TCCCTGGGGG ACACCATTGG TGTGGGCACC CCAGGGATCA TGAAAGACAT GCTATCTGCT
    GTCATGCAGG AAGTGCCTCT GGCTGCCCTG GCTGTCCACT GCCATGACAC CTATGGTCAA
    GCCCTGGCCA ACACCTTGAT GGCCCTGCAG ATGGGAGTGA GTGTCGTGGA CTCTTCTGTG
    GCAGGACTTG GAGGCTGTCC CTACGCACAG GGGGCATCAG GAAACTTGGC CACAGAAGAC
    CTGGTCTACA TGCTAGAGGG CTTGGGCATT CACACGGGTG TGAATCTCCA GAAGCTTCTG
    GAAGCTGGAA ACTTTATCTG TCAAGCCCTG AACAGAAAAA CTAGCTCCAA AGTGGCTCAG
    GCTACCTGTA AACTCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_000182.2
    CDS45..1022
    Translation

    Target ORF information:

    RefSeq Version NM_000191.2
    Organism Homo sapiens(human)
    Definition Homo sapiens 3-hydroxymethyl-3-methylglutaryl-CoA lyase (HMGCL), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_000191.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGGCAGCAA TGAGGAAGGC GCTTCCGCGG CGACTGGTGG GCTTGGCGTC CCTCCGGGCT 
    GTCAGCACCT CATCTATGGG CACTTTACCA AAGCGGGTGA AAATTGTGGA AGTTGGTCCC
    CGAGATGGAC TACAAAATGA AAAGAATATC GTATCTACTC CAGTGAAAAT CAAGCTGATA
    GACATGCTTT CTGAAGCAGG ACTCTCTGTT ATAGAAACCA CCAGCTTTGT GTCTCCTAAG
    TGGGTTCCCC AGATGGGTGA CCACACTGAA GTCTTGAAGG GCATTCAGAA GTTTCCTGGC
    ATCAACTACC CAGTCCTGAC CCCAAATTTG AAAGGCTTCG AGGCAGCGGT TGCTGCTGGA
    GCCAAGGAAG TAGTCATCTT TGGAGCTGCC TCAGAGCTCT TCACCAAGAA GAACATCAAT
    TGTTCCATAG AGGAGAGTTT TCAGAGGTTT GACGCAATCC TGAAGGCAGC GCAGTCAGCC
    AATATTTCTG TGCGGGGGTA CGTCTCCTGT GCTCTTGGCT GCCCTTATGA AGGGAAGATC
    TCCCCAGCTA AAGTAGCTGA GGTCACCAAG AAGTTCTACT CAATGGGCTG CTACGAGATC
    TCCCTGGGGG ACACCATTGG TGTGGGCACC CCAGGGATCA TGAAAGACAT GCTATCTGCT
    GTCATGCAGG AAGTGCCTCT GGCTGCCCTG GCTGTCCACT GCCATGACAC CTATGGTCAA
    GCCCTGGCCA ACACCTTGAT GGCCCTGCAG ATGGGAGTGA GTGTCGTGGA CTCTTCTGTG
    GCAGGACTTG GAGGCTGTCC CTACGCACAG GGGGCATCAG GAAACTTGGC CACAGAAGAC
    CTGGTCTACA TGCTAGAGGG CTTGGGCATT CACACGGGTG TGAATCTCCA GAAGCTTCTG
    GAAGCTGGAA ACTTTATCTG TCAAGCCCTG AACAGAAAAA CTAGCTCCAA AGTGGCTCAG
    GCTACCTGTA AACTCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu24855
    Clone ID Related Accession (Same CDS sequence) NM_001166059.1
    Accession Version NM_001166059.1 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 765bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-12-24
    Organism Homo sapiens(human)
    Product hydroxymethylglutaryl-CoA lyase, mitochondrial isoform 2 precursor
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA425822.1, L07033.1, BC010570.1, CA306929.1 and BM981610.1. Transcript Variant: This variant is missing two consecutive in-frame coding exons compared to variant 1, resulting in a shorter isoform (2) lacking an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.459798.1, SRR1163657.34239.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGCAGCAA TGAGGAAGGC GCTTCCGCGG CGACTGGTGG GCTTGGCGTC CCTCCGGGCT 
    GTCAGCACCT CATCTATGGG CACTTTACCA AAGCGGGTGA AAATTGTGGA AGTTGGTCCC
    CGAGATGGAC TACAAAATGA AAAGAATATC GTATCTACTC CAGTGAAAAT CAAGCTGATA
    GACATGCTTT CTGAAGCAGG ACTCTCTGTT ATAGAAACCA CCAGCTTTGT GTCTCCTAAG
    TGGGTTCCCC AGATGGGTGA CCACACTGAA GTCTTGAAGG GCATTCAGAA GTTTCCTGGC
    ATCAACTACC CAGTCCTGAC CCCAAATTTG AAAGGCTTCG AGGCAGCGGT CACCAAGAAG
    TTCTACTCAA TGGGCTGCTA CGAGATCTCC CTGGGGGACA CCATTGGTGT GGGCACCCCA
    GGGATCATGA AAGACATGCT ATCTGCTGTC ATGCAGGAAG TGCCTCTGGC TGCCCTGGCT
    GTCCACTGCC ATGACACCTA TGGTCAAGCC CTGGCCAACA CCTTGATGGC CCTGCAGATG
    GGAGTGAGTG TCGTGGACTC TTCTGTGGCA GGACTTGGAG GCTGTCCCTA CGCACAGGGG
    GCATCAGGAA ACTTGGCCAC AGAAGACCTG GTCTACATGC TAGAGGGCTT GGGCATTCAC
    ACGGGTGTGA ATCTCCAGAA GCTTCTGGAA GCTGGAAACT TTATCTGTCA AGCCCTGAAC
    AGAAAAACTA GCTCCAAAGT GGCTCAGGCT ACCTGTAAAC TCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001159531.1
    CDS45..809
    Translation

    Target ORF information:

    RefSeq Version NM_001166059.1
    Organism Homo sapiens(human)
    Definition Homo sapiens 3-hydroxy-3-methylglutaryl-CoA lyase (HMGCL), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001166059.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGGCAGCAA TGAGGAAGGC GCTTCCGCGG CGACTGGTGG GCTTGGCGTC CCTCCGGGCT 
    GTCAGCACCT CATCTATGGG CACTTTACCA AAGCGGGTGA AAATTGTGGA AGTTGGTCCC
    CGAGATGGAC TACAAAATGA AAAGAATATC GTATCTACTC CAGTGAAAAT CAAGCTGATA
    GACATGCTTT CTGAAGCAGG ACTCTCTGTT ATAGAAACCA CCAGCTTTGT GTCTCCTAAG
    TGGGTTCCCC AGATGGGTGA CCACACTGAA GTCTTGAAGG GCATTCAGAA GTTTCCTGGC
    ATCAACTACC CAGTCCTGAC CCCAAATTTG AAAGGCTTCG AGGCAGCGGT CACCAAGAAG
    TTCTACTCAA TGGGCTGCTA CGAGATCTCC CTGGGGGACA CCATTGGTGT GGGCACCCCA
    GGGATCATGA AAGACATGCT ATCTGCTGTC ATGCAGGAAG TGCCTCTGGC TGCCCTGGCT
    GTCCACTGCC ATGACACCTA TGGTCAAGCC CTGGCCAACA CCTTGATGGC CCTGCAGATG
    GGAGTGAGTG TCGTGGACTC TTCTGTGGCA GGACTTGGAG GCTGTCCCTA CGCACAGGGG
    GCATCAGGAA ACTTGGCCAC AGAAGACCTG GTCTACATGC TAGAGGGCTT GGGCATTCAC
    ACGGGTGTGA ATCTCCAGAA GCTTCTGGAA GCTGGAAACT TTATCTGTCA AGCCCTGAAC
    AGAAAAACTA GCTCCAAAGT GGCTCAGGCT ACCTGTAAAC TCTGA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

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