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ITPA cDNA ORF clone, Homo sapiens (human)

Gene Symbol ITPA
Entrez Gene ID 3704
Full Name inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
Synonyms C20orf37, HLC14-06-P, My049, dJ794I6.3
General protein information
Preferred Names
inosine triphosphate pyrophosphatase
Names
inosine triphosphate pyrophosphatase
ITPase
NTPase
inosine triphosphatase-A
putative oncogene protein HLC14-06-P
nucleoside-triphosphate diphosphatase
non-standard purine NTP pyrophosphatase
non-canonical purine NTP pyrophosphatase
inosine triphosphate pyrophosphohydrolase
NP_001254552.1
NP_258412.1
NP_852470.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20p

Summary This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]. lac of sum
Disorder MIM:

147520

Disorder Html: [Inosine triphosphatase deficiency] (3)

mRNA and Protein(s)

mRNA Protein Name
XM_006723564 XP_006723627 inosine triphosphate pyrophosphatase isoform X1
XM_006723565 XP_006723628 inosine triphosphate pyrophosphatase isoform X2
XM_011529234 XP_011527536 inosine triphosphate pyrophosphatase isoform X3
XM_011529235 XP_011527537 inosine triphosphate pyrophosphatase isoform X4
NM_033453 NP_258412 inosine triphosphate pyrophosphatase isoform a
NM_181493 NP_852470 inosine triphosphate pyrophosphatase isoform b
NM_001267623 NP_001254552 inosine triphosphate pyrophosphatase isoform c



Homo sapiens (human) ITPA NP_258412.1
Pan troglodytes (chimpanzee) ITPA XP_003953718.1
Macaca mulatta (Rhesus monkey) ITPA XP_001115179.1
Canis lupus familiaris (dog) ITPA XP_851574.3
Bos taurus (cattle) ITPA NP_001069750.1
Mus musculus (house mouse) Itpa NP_080198.2
Rattus norvegicus (Norway rat) Itpa NP_001101244.1
Gallus gallus (chicken) ITPA NP_001258859.1
Danio rerio (zebrafish) itpa XP_005160503.1
Danio rerio (zebrafish) LOC101882233 XP_005160507.1
Drosophila melanogaster (fruit fly) CG8891 NP_608890.1
Caenorhabditis elegans hap-1 NP_498121.1
Arabidopsis thaliana (thale cress) AT4G13720 NP_567410.1
Xenopus (Silurana) tropicalis (western clawed frog) itpa XP_002934214.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following ITPA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITPA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu52713 XM_006723564 PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu52714 XM_006723565 PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu58519 XM_011529234 PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu58520 XM_011529235 PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu23700
NM_033453 Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00
OHu23830 NM_181493 Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu23901 NM_001267623 Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu52713
Clone ID Related Accession (Same CDS sequence) XM_006723564
Accession Version XM_006723564.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 717bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product inosine triphosphate pyrophosphatase isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011387.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578835408. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GGAACGCTGT
CATAGTAGCC GGCATCTGGC TTGTCCACGG AGTTCAGGGG CCGGATCGTG GCACCCAGAG
GCTGCCAGGA CTTTGGCTGG GACCCCTGCT TTCAGCCTGA TGGATATGAG CAGACGTACG
CAGAGATGCC TAAGGCGGAG AAGAACGCTG TCTCCCATCG CTTCCGGGCC CTGCTGGAGC
TGCAGGAGTA CTTTGGCAGT TTGGCAGCTT GACTTCTGCA GCTGGAGGAG GCCCCTCAGG
CCGGGGATCT GGGGAGGGCT AGCCCAAAAC CTCCCGCATC GGGCAGGCAC CCCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006723627.1
CDS489..1205
Misc Feature(1)516..>896(+)
Misc Feature(2)534..830(+)
Misc Feature(3)618..758(+)
Translation

Target ORF information:

RefSeq Version XM_006723564
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006723564

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GGAACGCTGT
CATAGTAGCC GGCATCTGGC TTGTCCACGG AGTTCAGGGG CCGGATCGTG GCACCCAGAG
GCTGCCAGGA CTTTGGCTGG GACCCCTGCT TTCAGCCTGA TGGATATGAG CAGACGTACG
CAGAGATGCC TAAGGCGGAG AAGAACGCTG TCTCCCATCG CTTCCGGGCC CTGCTGGAGC
TGCAGGAGTA CTTTGGCAGT TTGGCAGCTT GACTTCTGCA GCTGGAGGAG GCCCCTCAGG
CCGGGGATCT GGGGAGGGCT AGCCCAAAAC CTCCCGCATC GGGCAGGCAC CCCCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu52714
Clone ID Related Accession (Same CDS sequence) XM_006723565
Accession Version XM_006723565.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 594bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product inosine triphosphate pyrophosphatase isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011387.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578835410. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTAC AGGGGCCCGT GCTGGTTGAG GACACTTGTC TGTGCTTCAA TGCCCTTGGA
GGGCTCCCCG GCCCCTACAT AAAGTGGTTT CTGGAGAAGT TAAAGCCTGA AGGTCTCCAC
CAGCTCCTGG CCGGGTTCGA GGACAAGTCA GCCTATGCGC TCTGCACGTT TGCACTCAGC
ACCGGGGACC CAAGCCAGCC CGTGCGCCTG TTCAGGGGCC GGACCTCGGA ACGCTGTCAT
AGTAGCCGGC ATCTGGCTTG TCCACGGAGT TCAGGGGCCG GATCGTGGCA CCCAGAGGCT
GCCAGGACTT TGGCTGGGAC CCCTGCTTTC AGCCTGATGG ATATGAGCAG ACGTACGCAG
AGATGCCTAA GGCGGAGAAG AACGCTGTCT CCCATCGCTT CCGGGCCCTG CTGGAGCTGC
AGGAGTACTT TGGCAGTTTG GCAGCTTGAC TTCTGCAGCT GGAGGAGGCC CCTCAGGCCG
GGGATCTGGG GAGGGCTAGC CCAAAACCTC CCGCATCGGG CAGGCACCCC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006723628.1
CDS495..1088
Misc Feature(1)522..>779(+)
Misc Feature(2)534..587(+)
Translation

Target ORF information:

RefSeq Version XM_006723565
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006723565

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTAC AGGGGCCCGT GCTGGTTGAG GACACTTGTC TGTGCTTCAA TGCCCTTGGA
GGGCTCCCCG GCCCCTACAT AAAGTGGTTT CTGGAGAAGT TAAAGCCTGA AGGTCTCCAC
CAGCTCCTGG CCGGGTTCGA GGACAAGTCA GCCTATGCGC TCTGCACGTT TGCACTCAGC
ACCGGGGACC CAAGCCAGCC CGTGCGCCTG TTCAGGGGCC GGACCTCGGA ACGCTGTCAT
AGTAGCCGGC ATCTGGCTTG TCCACGGAGT TCAGGGGCCG GATCGTGGCA CCCAGAGGCT
GCCAGGACTT TGGCTGGGAC CCCTGCTTTC AGCCTGATGG ATATGAGCAG ACGTACGCAG
AGATGCCTAA GGCGGAGAAG AACGCTGTCT CCCATCGCTT CCGGGCCCTG CTGGAGCTGC
AGGAGTACTT TGGCAGTTTG GCAGCTTGAC TTCTGCAGCT GGAGGAGGCC CCTCAGGCCG
GGGATCTGGG GAGGGCTAGC CCAAAACCTC CCGCATCGGG CAGGCACCCC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58519
Clone ID Related Accession (Same CDS sequence) XM_011529234
Accession Version XM_011529234.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 444bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product inosine triphosphate pyrophosphatase isoform X3
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011387.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GGGAAACAGT
TGGCTAACAG CTCCTGAGGC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011527536.1
CDS488..931
Misc Feature(1)515..>901(+)
Misc Feature(2)533..829(+)
Misc Feature(3)617..757(+)
Translation

Target ORF information:

RefSeq Version XM_011529234
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011529234

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GGGAAACAGT
TGGCTAACAG CTCCTGAGGC CTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu58520
Clone ID Related Accession (Same CDS sequence) XM_011529235
Accession Version XM_011529235.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 417bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product inosine triphosphate pyrophosphatase isoform X4
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_011387.9) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GTTTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011527537.1
CDS485..901
Misc Feature(1)512..>892(+)
Misc Feature(2)530..826(+)
Misc Feature(3)614..754(+)
Translation

Target ORF information:

RefSeq Version XM_011529235
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011529235

ORF Insert Sequence:

1
61
121
181
241
301
361
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GTTTTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23700
Clone ID Related Accession (Same CDS sequence) NM_033453
Accession Version NM_033453.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 585bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product inosine triphosphate pyrophosphatase isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM560812.1, AF026816.2 and CA425905.1. This sequence is a reference standard in the RefSeqGene project. On Jun 9, 2012 this sequence version replaced gi:31657145. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM560812.1, AF219116.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GGGCCGGATC
GTGGCACCCA GAGGCTGCCA GGACTTTGGC TGGGACCCCT GCTTTCAGCC TGATGGATAT
GAGCAGACGT ACGCAGAGAT GCCTAAGGCG GAGAAGAACG CTGTCTCCCA TCGCTTCCGG
GCCCTGCTGG AGCTGCAGGA GTACTTTGGC AGTTTGGCAG CTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_258412.1
CDS193..777
Misc Feature(1)178..180(+)
Misc Feature(2)196..198(+)
Misc Feature(3)220..756(+)
Misc Feature(4)232..249(+)
Misc Feature(5)238..726(+)
Misc Feature(6)322..462(+)
Misc Feature(7)406..411(+)
Misc Feature(8)637..648(+)
Misc Feature(9)721..726(+)
Exon (1)1..258
Gene:ITPA
Gene Synonym:
Exon (2)259..316
Gene:ITPA
Gene Synonym:
Exon (3)317..381
Gene:ITPA
Gene Synonym:
Exon (4)382..455
Gene:ITPA
Gene Synonym:
Exon (5)456..487
Gene:ITPA
Gene Synonym:
Exon (6)488..603
Gene:ITPA
Gene Synonym:
Exon (7)604..680
Gene:ITPA
Gene Synonym:
Exon (8)681..1185
Gene:ITPA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_033453
Organism Homo sapiens (human)
Definition Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_033453

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTCG TTCAGATTCT AGGAGATAAG TTTCCATGCA CTTTGGTGGC ACAGAAAATT
GACCTGCCGG AGTACCAGGG GGAGCCGGAT GAGATTTCCA TACAGAAATG TCAGGAGGCA
GTTCGCCAGG TACAGGGGCC CGTGCTGGTT GAGGACACTT GTCTGTGCTT CAATGCCCTT
GGAGGGCTCC CCGGCCCCTA CATAAAGTGG TTTCTGGAGA AGTTAAAGCC TGAAGGTCTC
CACCAGCTCC TGGCCGGGTT CGAGGACAAG TCAGCCTATG CGCTCTGCAC GTTTGCACTC
AGCACCGGGG ACCCAAGCCA GCCCGTGCGC CTGTTCAGGG GCCGGACCTC GGGCCGGATC
GTGGCACCCA GAGGCTGCCA GGACTTTGGC TGGGACCCCT GCTTTCAGCC TGATGGATAT
GAGCAGACGT ACGCAGAGAT GCCTAAGGCG GAGAAGAACG CTGTCTCCCA TCGCTTCCGG
GCCCTGCTGG AGCTGCAGGA GTACTTTGGC AGTTTGGCAG CTTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23830
Clone ID Related Accession (Same CDS sequence) NM_181493
Accession Version NM_181493.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 534bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product inosine triphosphate pyrophosphatase isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AV694278.1, EF213026.1, AF026816.2 and CA425905.1. On Jun 9, 2012 this sequence version replaced gi:31657143. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region compared to variant 1, resulting in a shorter protein (isoform b) compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BM910626.1, BG332818.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

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ATGGCGGCCT CATTGGTCGT TCAGATTCTA GGAGATAAGT TTCCATGCAC TTTGGTGGCA 
CAGAAAATTG ACCTGCCGGA GTACCAGGGG GAGCCGGATG AGATTTCCAT ACAGAAATGT
CAGGAGGCAG TTCGCCAGGT ACAGGGGCCC GTGCTGGTTG AGGACACTTG TCTGTGCTTC
AATGCCCTTG GAGGGCTCCC CGGCCCCTAC ATAAAGTGGT TTCTGGAGAA GTTAAAGCCT
GAAGGTCTCC ACCAGCTCCT GGCCGGGTTC GAGGACAAGT CAGCCTATGC GCTCTGCACG
TTTGCACTCA GCACCGGGGA CCCAAGCCAG CCCGTGCGCC TGTTCAGGGG CCGGACCTCG
GGCCGGATCG TGGCACCCAG AGGCTGCCAG GACTTTGGCT GGGACCCCTG CTTTCAGCCT
GATGGATATG AGCAGACGTA CGCAGAGATG CCTAAGGCGG AGAAGAACGC TGTCTCCCAT
CGCTTCCGGG CCCTGCTGGA GCTGCAGGAG TACTTTGGCA GTTTGGCAGC TTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_852470.1
CDS65..598
Misc Feature(1)50..52(+)
Misc Feature(2)86..577(+)
Misc Feature(3)143..283(+)
Misc Feature(4)230..547(+)
Exon (1)1..79
Gene:ITPA
Gene Synonym:
Exon (2)80..137
Gene:ITPA
Gene Synonym:
Exon (3)138..202
Gene:ITPA
Gene Synonym:
Exon (4)203..276
Gene:ITPA
Gene Synonym:
Exon (5)277..308
Gene:ITPA
Gene Synonym:
Exon (6)309..424
Gene:ITPA
Gene Synonym:
Exon (7)425..501
Gene:ITPA
Gene Synonym:
Exon (8)502..1006
Gene:ITPA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_181493
Organism Homo sapiens (human)
Definition Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_181493

ORF Insert Sequence:

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181
241
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361
421
481
ATGGCGGCCT CATTGGTCGT TCAGATTCTA GGAGATAAGT TTCCATGCAC TTTGGTGGCA 
CAGAAAATTG ACCTGCCGGA GTACCAGGGG GAGCCGGATG AGATTTCCAT ACAGAAATGT
CAGGAGGCAG TTCGCCAGGT ACAGGGGCCC GTGCTGGTTG AGGACACTTG TCTGTGCTTC
AATGCCCTTG GAGGGCTCCC CGGCCCCTAC ATAAAGTGGT TTCTGGAGAA GTTAAAGCCT
GAAGGTCTCC ACCAGCTCCT GGCCGGGTTC GAGGACAAGT CAGCCTATGC GCTCTGCACG
TTTGCACTCA GCACCGGGGA CCCAAGCCAG CCCGTGCGCC TGTTCAGGGG CCGGACCTCG
GGCCGGATCG TGGCACCCAG AGGCTGCCAG GACTTTGGCT GGGACCCCTG CTTTCAGCCT
GATGGATATG AGCAGACGTA CGCAGAGATG CCTAAGGCGG AGAAGAACGC TGTCTCCCAT
CGCTTCCGGG CCCTGCTGGA GCTGCAGGAG TACTTTGGCA GTTTGGCAGC TTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23901
Clone ID Related Accession (Same CDS sequence) NM_001267623
Accession Version NM_001267623.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 462bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product inosine triphosphate pyrophosphatase isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BM560812.1, BI115811.1, AF026816.2 and CA425905.1. Transcript Variant: This variant (3) lacks two in-frame exons in the coding region, compared to variant 1. The encoded isoform (c) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI115811.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

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ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTAC AGGGGCCCGT GCTGGTTGAG GACACTTGTC TGTGCTTCAA TGCCCTTGGA
GGGCTCCCCG GCCCCTACAT AAAGTGGTTT CTGGAGAAGT TAAAGCCTGA AGGTCTCCAC
CAGCTCCTGG CCGGGTTCGA GGACAAGTCA GCCTATGCGC TCTGCACGTT TGCACTCAGC
ACCGGGGACC CAAGCCAGCC CGTGCGCCTG TTCAGGGGCC GGACCTCGGG CCGGATCGTG
GCACCCAGAG GCTGCCAGGA CTTTGGCTGG GACCCCTGCT TTCAGCCTGA TGGATATGAG
CAGACGTACG CAGAGATGCC TAAGGCGGAG AAGAACGCTG TCTCCCATCG CTTCCGGGCC
CTGCTGGAGC TGCAGGAGTA CTTTGGCAGT TTGGCAGCTT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001254552.1
CDS193..654
Misc Feature(1)178..180(+)
Misc Feature(2)220..633(+)
Misc Feature(3)238..603(+)
Misc Feature(4)307..339(+)
Exon (1)1..258
Gene:ITPA
Gene Synonym:
Exon (2)259..332
Gene:ITPA
Gene Synonym:
Exon (3)333..364
Gene:ITPA
Gene Synonym:
Exon (4)365..480
Gene:ITPA
Gene Synonym:
Exon (5)481..557
Gene:ITPA
Gene Synonym:
Exon (6)558..1062
Gene:ITPA
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001267623
Organism Homo sapiens (human)
Definition Homo sapiens inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001267623

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCGGCCT CATTGGTGGG GAAGAAGATC GTGTTTGTAA CGGGGAACGC CAAGAAGCTG 
GAGGAGGTAC AGGGGCCCGT GCTGGTTGAG GACACTTGTC TGTGCTTCAA TGCCCTTGGA
GGGCTCCCCG GCCCCTACAT AAAGTGGTTT CTGGAGAAGT TAAAGCCTGA AGGTCTCCAC
CAGCTCCTGG CCGGGTTCGA GGACAAGTCA GCCTATGCGC TCTGCACGTT TGCACTCAGC
ACCGGGGACC CAAGCCAGCC CGTGCGCCTG TTCAGGGGCC GGACCTCGGG CCGGATCGTG
GCACCCAGAG GCTGCCAGGA CTTTGGCTGG GACCCCTGCT TTCAGCCTGA TGGATATGAG
CAGACGTACG CAGAGATGCC TAAGGCGGAG AAGAACGCTG TCTCCCATCG CTTCCGGGCC
CTGCTGGAGC TGCAGGAGTA CTTTGGCAGT TTGGCAGCTT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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