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LAMP2 cDNA ORF clone, Homo sapiens (human)

Gene Symbol LAMP2
Entrez Gene ID 3920
Full Name lysosomal-associated membrane protein 2
Synonyms CD107b, LAMP-2, LAMPB, LGP110
General protein information
Preferred Names
lysosome-associated membrane glycoprotein 2
Names
lysosome-associated membrane glycoprotein 2
CD107 antigen-like family member B
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

X

Xq24

Summary The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

309060

Disorder Html: Glycogen storage disease IIb, 300257 (3)

mRNA and Protein(s)

mRNA Protein Name
NM_002294 NP_002285 lysosome-associated membrane glycoprotein 2 isoform A precursor
NM_013995 NP_054701 lysosome-associated membrane glycoprotein 2 isoform B precursor
NM_001122606 NP_001116078 lysosome-associated membrane glycoprotein 2 isoform C precursor



Homo sapiens (human) LAMP2 NP_002285.1
Pan troglodytes (chimpanzee) LAMP2 XP_003317709.1
Macaca mulatta (Rhesus monkey) LAMP2 XP_001084005.2
Canis lupus familiaris (dog) LAMP2 XP_005641822.1
Bos taurus (cattle) LAMP2 NP_001029742.1
Mus musculus (house mouse) Lamp2 NP_034815.2
Rattus norvegicus (Norway rat) Lamp2 NP_058764.2
Gallus gallus (chicken) LAMP2 NP_001001749.1
Xenopus (Silurana) tropicalis (western clawed frog) lamp2 NP_001116192.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following LAMP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LAMP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu23655
NM_002294 Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant A, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$159.50-$223.30
$319.00
OHu23847 NM_013995 Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant B, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu23862 NM_001122606 Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant C, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu23655
Clone ID Related Accession (Same CDS sequence) NM_002294
Accession Version NM_002294.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1233bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product lysosome-associated membrane glycoprotein 2 isoform A precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA405328.1, X77196.1, AC002476.1 and BC040653.2. This sequence is a reference standard in the RefSeqGene project. On Mar 12, 2008 this sequence version replaced gi:4504956. Transcript Variant: This variant (A) is the longest and predominant form of this gene. Variant A encodes isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X77196.1, AK291090.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGTGTGCT TCCGCCTCTT CCCGGTTCCG GGCTCAGGGC TCGTTCTGGT CTGCCTAGTC 
CTGGGAGCTG TGCGGTCTTA TGCATTGGAA CTTAATTTGA CAGATTCAGA AAATGCCACT
TGCCTTTATG CAAAATGGCA GATGAATTTC ACAGTACGCT ATGAAACTAC AAATAAAACT
TATAAAACTG TAACCATTTC AGACCATGGC ACTGTGACAT ATAATGGAAG CATTTGTGGG
GATGATCAGA ATGGTCCCAA AATAGCAGTG CAGTTCGGAC CTGGCTTTTC CTGGATTGCG
AATTTTACCA AGGCAGCATC TACTTATTCA ATTGACAGCG TCTCATTTTC CTACAACACT
GGTGATAACA CAACATTTCC TGATGCTGAA GATAAAGGAA TTCTTACTGT TGATGAACTT
TTGGCCATCA GAATTCCATT GAATGACCTT TTTAGATGCA ATAGTTTATC AACTTTGGAA
AAGAATGATG TTGTCCAACA CTACTGGGAT GTTCTTGTAC AAGCTTTTGT CCAAAATGGC
ACAGTGAGCA CAAATGAGTT CCTGTGTGAT AAAGACAAAA CTTCAACAGT GGCACCCACC
ATACACACCA CTGTGCCATC TCCTACTACA ACACCTACTC CAAAGGAAAA ACCAGAAGCT
GGAACCTATT CAGTTAATAA TGGCAATGAT ACTTGTCTGC TGGCTACCAT GGGGCTGCAG
CTGAACATCA CTCAGGATAA GGTTGCTTCA GTTATTAACA TCAACCCCAA TACAACTCAC
TCCACAGGCA GCTGCCGTTC TCACACTGCT CTACTTAGAC TCAATAGCAG CACCATTAAG
TATCTAGACT TTGTCTTTGC TGTGAAAAAT GAAAACCGAT TTTATCTGAA GGAAGTGAAC
ATCAGCATGT ATTTGGTTAA TGGCTCCGTT TTCAGCATTG CAAATAACAA TCTCAGCTAC
TGGGATGCCC CCCTGGGAAG TTCTTATATG TGCAACAAAG AGCAGACTGT TTCAGTGTCT
GGAGCATTTC AGATAAATAC CTTTGATCTA AGGGTTCAGC CTTTCAATGT GACACAAGGA
AAGTATTCTA CAGCTCAAGA CTGCAGTGCA GATGACGACA ACTTCCTTGT GCCCATAGCG
GTGGGAGCTG CCTTGGCAGG AGTACTTATT CTAGTGTTGC TGGCTTATTT TATTGGTCTC
AAGCACCATC ATGCTGGATA TGAGCAATTT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002285.1
CDS181..1413
Misc Feature(1)37..39(+)
Misc Feature(2)265..756(+)
Misc Feature(3)274..276(+)
Misc Feature(4)292..294(+)
Misc Feature(5)325..327(+)
Misc Feature(6)352..354(+)
Misc Feature(7)505..1410(+)
Misc Feature(8)757..864(+)
Misc Feature(9)763..765(+)
Misc Feature(10)766..768(+)
Misc Feature(11)778..780(+)
Misc Feature(12)787..789(+)
Misc Feature(13)790..792(+)
Misc Feature(14)799..801(+)
Misc Feature(15)805..807(+)
Misc Feature(16)808..810(+)
Misc Feature(17)811..813(+)
Misc Feature(18)865..1305(+)
Misc Feature(19)904..906(+)
Misc Feature(20)1099..1101(+)
Misc Feature(21)1303..1305(+)
Misc Feature(22)1306..1377(+)
Exon (1)1..244
Gene:LAMP2
Gene Synonym:
Exon (2)245..363
Gene:LAMP2
Gene Synonym:
Exon (3)364..577
Gene:LAMP2
Gene Synonym:
Exon (4)578..736
Gene:LAMP2
Gene Synonym:
Exon (5)737..921
Gene:LAMP2
Gene Synonym:
Exon (6)922..1044
Gene:LAMP2
Gene Synonym:
Exon (7)1045..1108
Gene:LAMP2
Gene Synonym:
Exon (8)1109..1273
Gene:LAMP2
Gene Synonym:
Exon (9)1274..6588
Gene:LAMP2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002294
Organism Homo sapiens (human)
Definition Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant A, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002294

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGTGTGCT TCCGCCTCTT CCCGGTTCCG GGCTCAGGGC TCGTTCTGGT CTGCCTAGTC 
CTGGGAGCTG TGCGGTCTTA TGCATTGGAA CTTAATTTGA CAGATTCAGA AAATGCCACT
TGCCTTTATG CAAAATGGCA GATGAATTTC ACAGTACGCT ATGAAACTAC AAATAAAACT
TATAAAACTG TAACCATTTC AGACCATGGC ACTGTGACAT ATAATGGAAG CATTTGTGGG
GATGATCAGA ATGGTCCCAA AATAGCAGTG CAGTTCGGAC CTGGCTTTTC CTGGATTGCG
AATTTTACCA AGGCAGCATC TACTTATTCA ATTGACAGCG TCTCATTTTC CTACAACACT
GGTGATAACA CAACATTTCC TGATGCTGAA GATAAAGGAA TTCTTACTGT TGATGAACTT
TTGGCCATCA GAATTCCATT GAATGACCTT TTTAGATGCA ATAGTTTATC AACTTTGGAA
AAGAATGATG TTGTCCAACA CTACTGGGAT GTTCTTGTAC AAGCTTTTGT CCAAAATGGC
ACAGTGAGCA CAAATGAGTT CCTGTGTGAT AAAGACAAAA CTTCAACAGT GGCACCCACC
ATACACACCA CTGTGCCATC TCCTACTACA ACACCTACTC CAAAGGAAAA ACCAGAAGCT
GGAACCTATT CAGTTAATAA TGGCAATGAT ACTTGTCTGC TGGCTACCAT GGGGCTGCAG
CTGAACATCA CTCAGGATAA GGTTGCTTCA GTTATTAACA TCAACCCCAA TACAACTCAC
TCCACAGGCA GCTGCCGTTC TCACACTGCT CTACTTAGAC TCAATAGCAG CACCATTAAG
TATCTAGACT TTGTCTTTGC TGTGAAAAAT GAAAACCGAT TTTATCTGAA GGAAGTGAAC
ATCAGCATGT ATTTGGTTAA TGGCTCCGTT TTCAGCATTG CAAATAACAA TCTCAGCTAC
TGGGATGCCC CCCTGGGAAG TTCTTATATG TGCAACAAAG AGCAGACTGT TTCAGTGTCT
GGAGCATTTC AGATAAATAC CTTTGATCTA AGGGTTCAGC CTTTCAATGT GACACAAGGA
AAGTATTCTA CAGCTCAAGA CTGCAGTGCA GATGACGACA ACTTCCTTGT GCCCATAGCG
GTGGGAGCTG CCTTGGCAGG AGTACTTATT CTAGTGTTGC TGGCTTATTT TATTGGTCTC
AAGCACCATC ATGCTGGATA TGAGCAATTT TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23847
Clone ID Related Accession (Same CDS sequence) NM_013995
Accession Version NM_013995.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1233bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product lysosome-associated membrane glycoprotein 2 isoform B precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA405328.1, S79873.1, AC002476.1 and BP386088.1. This sequence is a reference standard in the RefSeqGene project. On Mar 12, 2008 this sequence version replaced gi:7669502. Transcript Variant: This variant (B) results from alternative splicing of exon 9 and results in a shorter transcript, but not protein, as compared to variant A. Transcript variant B is over-expressed in muscle and encodes isoform B. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: S79873.1, U36336.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGTGTGCT TCCGCCTCTT CCCGGTTCCG GGCTCAGGGC TCGTTCTGGT CTGCCTAGTC 
CTGGGAGCTG TGCGGTCTTA TGCATTGGAA CTTAATTTGA CAGATTCAGA AAATGCCACT
TGCCTTTATG CAAAATGGCA GATGAATTTC ACAGTACGCT ATGAAACTAC AAATAAAACT
TATAAAACTG TAACCATTTC AGACCATGGC ACTGTGACAT ATAATGGAAG CATTTGTGGG
GATGATCAGA ATGGTCCCAA AATAGCAGTG CAGTTCGGAC CTGGCTTTTC CTGGATTGCG
AATTTTACCA AGGCAGCATC TACTTATTCA ATTGACAGCG TCTCATTTTC CTACAACACT
GGTGATAACA CAACATTTCC TGATGCTGAA GATAAAGGAA TTCTTACTGT TGATGAACTT
TTGGCCATCA GAATTCCATT GAATGACCTT TTTAGATGCA ATAGTTTATC AACTTTGGAA
AAGAATGATG TTGTCCAACA CTACTGGGAT GTTCTTGTAC AAGCTTTTGT CCAAAATGGC
ACAGTGAGCA CAAATGAGTT CCTGTGTGAT AAAGACAAAA CTTCAACAGT GGCACCCACC
ATACACACCA CTGTGCCATC TCCTACTACA ACACCTACTC CAAAGGAAAA ACCAGAAGCT
GGAACCTATT CAGTTAATAA TGGCAATGAT ACTTGTCTGC TGGCTACCAT GGGGCTGCAG
CTGAACATCA CTCAGGATAA GGTTGCTTCA GTTATTAACA TCAACCCCAA TACAACTCAC
TCCACAGGCA GCTGCCGTTC TCACACTGCT CTACTTAGAC TCAATAGCAG CACCATTAAG
TATCTAGACT TTGTCTTTGC TGTGAAAAAT GAAAACCGAT TTTATCTGAA GGAAGTGAAC
ATCAGCATGT ATTTGGTTAA TGGCTCCGTT TTCAGCATTG CAAATAACAA TCTCAGCTAC
TGGGATGCCC CCCTGGGAAG TTCTTATATG TGCAACAAAG AGCAGACTGT TTCAGTGTCT
GGAGCATTTC AGATAAATAC CTTTGATCTA AGGGTTCAGC CTTTCAATGT GACACAAGGA
AAGTATTCTA CAGCCCAAGA GTGTTCGCTG GATGATGACA CCATTCTAAT CCCAATTATA
GTTGGTGCTG GTCTTTCAGG CTTGATTATC GTTATAGTGA TTGCTTACGT AATTGGCAGA
AGAAAAAGTT ATGCTGGATA TCAGACTCTG TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_054701.1
CDS181..1413
Misc Feature(1)37..39(+)
Misc Feature(2)274..276(+)
Misc Feature(3)292..294(+)
Misc Feature(4)325..327(+)
Misc Feature(5)352..354(+)
Misc Feature(6)505..1410(+)
Misc Feature(7)763..765(+)
Misc Feature(8)766..768(+)
Misc Feature(9)778..780(+)
Misc Feature(10)787..789(+)
Misc Feature(11)790..792(+)
Misc Feature(12)799..801(+)
Misc Feature(13)805..807(+)
Misc Feature(14)808..810(+)
Misc Feature(15)811..813(+)
Misc Feature(16)904..906(+)
Misc Feature(17)1099..1101(+)
Exon (1)1..244
Gene:LAMP2
Gene Synonym:
Exon (2)245..363
Gene:LAMP2
Gene Synonym:
Exon (3)364..577
Gene:LAMP2
Gene Synonym:
Exon (4)578..736
Gene:LAMP2
Gene Synonym:
Exon (5)737..921
Gene:LAMP2
Gene Synonym:
Exon (6)922..1044
Gene:LAMP2
Gene Synonym:
Exon (7)1045..1108
Gene:LAMP2
Gene Synonym:
Exon (8)1109..1273
Gene:LAMP2
Gene Synonym:
Exon (9)1274..4073
Gene:LAMP2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_013995
Organism Homo sapiens (human)
Definition Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant B, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_013995

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGTGTGCT TCCGCCTCTT CCCGGTTCCG GGCTCAGGGC TCGTTCTGGT CTGCCTAGTC 
CTGGGAGCTG TGCGGTCTTA TGCATTGGAA CTTAATTTGA CAGATTCAGA AAATGCCACT
TGCCTTTATG CAAAATGGCA GATGAATTTC ACAGTACGCT ATGAAACTAC AAATAAAACT
TATAAAACTG TAACCATTTC AGACCATGGC ACTGTGACAT ATAATGGAAG CATTTGTGGG
GATGATCAGA ATGGTCCCAA AATAGCAGTG CAGTTCGGAC CTGGCTTTTC CTGGATTGCG
AATTTTACCA AGGCAGCATC TACTTATTCA ATTGACAGCG TCTCATTTTC CTACAACACT
GGTGATAACA CAACATTTCC TGATGCTGAA GATAAAGGAA TTCTTACTGT TGATGAACTT
TTGGCCATCA GAATTCCATT GAATGACCTT TTTAGATGCA ATAGTTTATC AACTTTGGAA
AAGAATGATG TTGTCCAACA CTACTGGGAT GTTCTTGTAC AAGCTTTTGT CCAAAATGGC
ACAGTGAGCA CAAATGAGTT CCTGTGTGAT AAAGACAAAA CTTCAACAGT GGCACCCACC
ATACACACCA CTGTGCCATC TCCTACTACA ACACCTACTC CAAAGGAAAA ACCAGAAGCT
GGAACCTATT CAGTTAATAA TGGCAATGAT ACTTGTCTGC TGGCTACCAT GGGGCTGCAG
CTGAACATCA CTCAGGATAA GGTTGCTTCA GTTATTAACA TCAACCCCAA TACAACTCAC
TCCACAGGCA GCTGCCGTTC TCACACTGCT CTACTTAGAC TCAATAGCAG CACCATTAAG
TATCTAGACT TTGTCTTTGC TGTGAAAAAT GAAAACCGAT TTTATCTGAA GGAAGTGAAC
ATCAGCATGT ATTTGGTTAA TGGCTCCGTT TTCAGCATTG CAAATAACAA TCTCAGCTAC
TGGGATGCCC CCCTGGGAAG TTCTTATATG TGCAACAAAG AGCAGACTGT TTCAGTGTCT
GGAGCATTTC AGATAAATAC CTTTGATCTA AGGGTTCAGC CTTTCAATGT GACACAAGGA
AAGTATTCTA CAGCCCAAGA GTGTTCGCTG GATGATGACA CCATTCTAAT CCCAATTATA
GTTGGTGCTG GTCTTTCAGG CTTGATTATC GTTATAGTGA TTGCTTACGT AATTGGCAGA
AGAAAAAGTT ATGCTGGATA TCAGACTCTG TAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23862
Clone ID Related Accession (Same CDS sequence) NM_001122606
Accession Version NM_001122606.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1236bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product lysosome-associated membrane glycoprotein 2 isoform C precursor
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC002476.1, AY561849.1 and BC040653.2. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (C) results from alternative splicing of exon 9 and results in a shorter transcript, but longer protein, as compared to variant A. Variant C encodes isoform C. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY561849.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGTGTGCT TCCGCCTCTT CCCGGTTCCG GGCTCAGGGC TCGTTCTGGT CTGCCTAGTC 
CTGGGAGCTG TGCGGTCTTA TGCATTGGAA CTTAATTTGA CAGATTCAGA AAATGCCACT
TGCCTTTATG CAAAATGGCA GATGAATTTC ACAGTACGCT ATGAAACTAC AAATAAAACT
TATAAAACTG TAACCATTTC AGACCATGGC ACTGTGACAT ATAATGGAAG CATTTGTGGG
GATGATCAGA ATGGTCCCAA AATAGCAGTG CAGTTCGGAC CTGGCTTTTC CTGGATTGCG
AATTTTACCA AGGCAGCATC TACTTATTCA ATTGACAGCG TCTCATTTTC CTACAACACT
GGTGATAACA CAACATTTCC TGATGCTGAA GATAAAGGAA TTCTTACTGT TGATGAACTT
TTGGCCATCA GAATTCCATT GAATGACCTT TTTAGATGCA ATAGTTTATC AACTTTGGAA
AAGAATGATG TTGTCCAACA CTACTGGGAT GTTCTTGTAC AAGCTTTTGT CCAAAATGGC
ACAGTGAGCA CAAATGAGTT CCTGTGTGAT AAAGACAAAA CTTCAACAGT GGCACCCACC
ATACACACCA CTGTGCCATC TCCTACTACA ACACCTACTC CAAAGGAAAA ACCAGAAGCT
GGAACCTATT CAGTTAATAA TGGCAATGAT ACTTGTCTGC TGGCTACCAT GGGGCTGCAG
CTGAACATCA CTCAGGATAA GGTTGCTTCA GTTATTAACA TCAACCCCAA TACAACTCAC
TCCACAGGCA GCTGCCGTTC TCACACTGCT CTACTTAGAC TCAATAGCAG CACCATTAAG
TATCTAGACT TTGTCTTTGC TGTGAAAAAT GAAAACCGAT TTTATCTGAA GGAAGTGAAC
ATCAGCATGT ATTTGGTTAA TGGCTCCGTT TTCAGCATTG CAAATAACAA TCTCAGCTAC
TGGGATGCCC CCCTGGGAAG TTCTTATATG TGCAACAAAG AGCAGACTGT TTCAGTGTCT
GGAGCATTTC AGATAAATAC CTTTGATCTA AGGGTTCAGC CTTTCAATGT GACACAAGGA
AAGTATTCTA CAGCTGAAGA ATGTTCTGCT GACTCTGACC TCAACTTTCT TATTCCTGTT
GCAGTGGGTG TGGCCTTGGG CTTCCTTATA ATTGTTGTCT TTATCTCTTA TATGATTGGA
AGAAGGAAAA GTCGTACTGG TTATCAGTCT GTGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001116078.1
CDS181..1416
Misc Feature(1)37..39(+)
Misc Feature(2)505..1413(+)
Exon (1)1..244
Gene:LAMP2
Gene Synonym:
Exon (2)245..363
Gene:LAMP2
Gene Synonym:
Exon (3)364..577
Gene:LAMP2
Gene Synonym:
Exon (4)578..736
Gene:LAMP2
Gene Synonym:
Exon (5)737..921
Gene:LAMP2
Gene Synonym:
Exon (6)922..1044
Gene:LAMP2
Gene Synonym:
Exon (7)1045..1108
Gene:LAMP2
Gene Synonym:
Exon (8)1109..1273
Gene:LAMP2
Gene Synonym:
Exon (9)1274..3752
Gene:LAMP2
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001122606
Organism Homo sapiens (human)
Definition Homo sapiens lysosomal-associated membrane protein 2 (LAMP2), transcript variant C, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001122606

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGTGTGCT TCCGCCTCTT CCCGGTTCCG GGCTCAGGGC TCGTTCTGGT CTGCCTAGTC 
CTGGGAGCTG TGCGGTCTTA TGCATTGGAA CTTAATTTGA CAGATTCAGA AAATGCCACT
TGCCTTTATG CAAAATGGCA GATGAATTTC ACAGTACGCT ATGAAACTAC AAATAAAACT
TATAAAACTG TAACCATTTC AGACCATGGC ACTGTGACAT ATAATGGAAG CATTTGTGGG
GATGATCAGA ATGGTCCCAA AATAGCAGTG CAGTTCGGAC CTGGCTTTTC CTGGATTGCG
AATTTTACCA AGGCAGCATC TACTTATTCA ATTGACAGCG TCTCATTTTC CTACAACACT
GGTGATAACA CAACATTTCC TGATGCTGAA GATAAAGGAA TTCTTACTGT TGATGAACTT
TTGGCCATCA GAATTCCATT GAATGACCTT TTTAGATGCA ATAGTTTATC AACTTTGGAA
AAGAATGATG TTGTCCAACA CTACTGGGAT GTTCTTGTAC AAGCTTTTGT CCAAAATGGC
ACAGTGAGCA CAAATGAGTT CCTGTGTGAT AAAGACAAAA CTTCAACAGT GGCACCCACC
ATACACACCA CTGTGCCATC TCCTACTACA ACACCTACTC CAAAGGAAAA ACCAGAAGCT
GGAACCTATT CAGTTAATAA TGGCAATGAT ACTTGTCTGC TGGCTACCAT GGGGCTGCAG
CTGAACATCA CTCAGGATAA GGTTGCTTCA GTTATTAACA TCAACCCCAA TACAACTCAC
TCCACAGGCA GCTGCCGTTC TCACACTGCT CTACTTAGAC TCAATAGCAG CACCATTAAG
TATCTAGACT TTGTCTTTGC TGTGAAAAAT GAAAACCGAT TTTATCTGAA GGAAGTGAAC
ATCAGCATGT ATTTGGTTAA TGGCTCCGTT TTCAGCATTG CAAATAACAA TCTCAGCTAC
TGGGATGCCC CCCTGGGAAG TTCTTATATG TGCAACAAAG AGCAGACTGT TTCAGTGTCT
GGAGCATTTC AGATAAATAC CTTTGATCTA AGGGTTCAGC CTTTCAATGT GACACAAGGA
AAGTATTCTA CAGCTGAAGA ATGTTCTGCT GACTCTGACC TCAACTTTCT TATTCCTGTT
GCAGTGGGTG TGGCCTTGGG CTTCCTTATA ATTGTTGTCT TTATCTCTTA TATGATTGGA
AGAAGGAAAA GTCGTACTGG TTATCAGTCT GTGTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Autoantibodies to hLAMP-2 in ANCA-negative pauci-immune focal necrotizing GN
J. Am. Soc. Nephrol. 25 (3), 455-463 (2014)
Peschel A, Basu N, Benharkou A, Brandes R, Brown M, Dieckmann R, Rees AJ and Kain R.


book

Lysosome-associated protein 1 (LAMP-1) and lysosome-associated protein 2 (LAMP-2) in a larger family carrier of Fabry disease
Gene 536 (1), 118-122 (2014)
Pereira EM, do Monte SJ, do Nascimento FF, de Castro JA, Sousa JL, Filho HC, da Silva RN, Labilloy A, Monte Neto JT and da Silva AS.


book

Lysosomal-associated membrane protein-2 plays an important role in the pathogenesis of primary cutaneous vasculitis
Rheumatology (Oxford) 52 (9), 1592-1598 (2013)
Takeuchi S, Kimura S, Soma Y, Waki M, Yamaguchi M, Nakazawa D, Tomaru U, Ishizu A and Kawakami T.


book

Stimulation of CD107 affects LPS-induced cytokine secretion and cellular adhesion through the ERK signaling pathway in the human macrophage-like cell line, THP-1
Cell. Immunol. 281 (2), 122-128 (2013)
Min BK, Suk K and Lee WH.


book

Influence of microRNA deregulation on chaperone-mediated autophagy and alpha-synuclein pathology in Parkinson's disease
Cell Death Dis 4, E545 (2013)
Alvarez-Erviti L, Seow Y, Schapira AH, Rodriguez-Oroz MC, Obeso JA and Cooper JM.


book

Unifying nomenclature for the isoforms of the lysosomal membrane protein LAMP-2
Traffic 6 (11), 1058-1061 (2005)
Eskelinen EL, Cuervo AM, Taylor MR, Nishino I, Blum JS, Dice JF, Sandoval IV, Lippincott-Schwartz J, August JT and Saftig P.


book

Isolation of dense granules from human platelets
Meth. Enzymol. 215, 36-42 (1992)
Fukami MH.


book

Confirmation of the chromosomal localization of human lamp genes and their exclusion as candidate genes for Salla disease
Hum. Genet. 88 (1), 95-97 (1991)
Schleutker J, Haataja L, Renlund M, Puhakka L, Viitala J, Peltonen L and Aula P.


book

The nucleotide sequence of a CpG island demonstrates the presence of the first exon of the gene encoding the human lysosomal membrane protein lamp2 and assigns the gene to Xq24
Genomics 9 (3), 551-554 (1991)
Manoni M, Tribioli C, Lazzari B, DeBellis G, Patrosso C, Pergolizzi R, Pellegrini M, Maestrini E, Rivella S and Vezzoni P.


book

The polylactosaminoglycans of human lysosomal membrane glycoproteins lamp-1 and lamp-2. Localization on the peptide backbones
J. Biol. Chem. 265 (33), 20488-20495 (1990)
Carlsson SR and Fukuda M.


 
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