PATE2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PATE2
Entrez Gene ID	399967
Full Name	prostate and testis expressed 2
Synonyms	C11orf38,PATE-M,UNQ3112
General protein information	Preferred Names prostate and testis expressed 2 Names prostate and testis expressed protein 2 LVLF3112 PATE-like protein M prostate and testis expression M
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q24.2

mRNA and Protein(s)

mRNA	Protein	Name
NM_212555.2	NP_997720.1	prostate and testis expressed protein 2 precursor
NM_212555.3	NP_997720.1	prostate and testis expressed protein 2 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	PATE2	XP_005619644.1
Mus musculus (house mouse)	Pate2	NP_001028593.1
Rattus norvegicus (Norway rat)	Pate2	NP_001254710.1
	PATE2	XP_001108287.2
Homo sapiens (human)	PATE2	NP_997720.1
Pan troglodytes (chimpanzee)	PATE2	XP_001148077.1
Bos taurus (cattle)	PATE2	XP_002699260.2

Gene Ontology
Bibliography

Related articles in PubMed

Involvement of the prostate and testis expression (PATE)-like proteins in sperm-oocyte interaction.
Margalit M, Yogev L, Yavetz H, Lehavi O, Hauser R, Botchan A, Barda S, Levitin F, Weiss M, Pastan I, Wreschner DH, Paz G, Kleiman SE
Human reproduction (Oxford, England)27(5)1238-48(2012 May)

PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.
Levitin F, Weiss M, Hahn Y, Stern O, Papke RL, Matusik R, Nandana SR, Ziv R, Pichinuk E, Salame S, Bera T, Vincent J, Lee B, Pastan I, Wreschner DH
The Journal of biological chemistry283(24)16928-39(2008 Jun)

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A
Genome research13(10)2265-70(2003 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

PATE proteins are involved in sperm-oolemma fusion and penetration but not sperm-zona binding.
Title: Involvement of the prostate and testis expression (PATE)-like proteins in sperm-oocyte interaction.

analysis of PATE, expressed primarily in prostate and less in testis, and additional PATE-like genes PATE-M, PATE-DJ, and PATE-B
Title: PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.

The following PATE2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PATE2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu01287	NM_212555.3 Latest version!	Homo sapiens prostate and testis expressed 2 (PATE2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu01287	NM_212555.2	Homo sapiens prostate and testis expressed 2 (PATE2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PATE2 ( NM_212555.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_997720.1 Homo sapiens prostate and testis expressed 2 (PATE2), mRNA.

Price & Availability↑

CloneID	OHu01287
Clone ID Related Accession (Same CDS sequence)	NM_212555.2 , NM_212555.3
Accession Version	NM_212555.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	prostate and testis expressed protein 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AY358105.1 and AP003087.2. On Jan 22, 2009 this sequence version replaced NM_212555.1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY358105.1, BC137190.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END##

ATGCTTGTTC TCTTTCTCCT GGGCACAGTC TTTCTGCTCT GCCCATATTG GGGTGAACTT 
CATGACCCTA TAAAAGCGAC TGAAATAATG TGTTATGAAT GTAAAAAATA TCATCTTGGG 
TTATGCTATG GTGTCATGAC ATCCTGCTCC CTGAAGCATA AACAGTCCTG TGCAGTTGAG 
AACTTTTACA TCCTTACAAG GAAAGGGCAG AGCATGTATC ATTATTCAAA ACTGTCGTGT 
ATGACCAGCT GTGAGGACAT CAACTTCCTG GGGTTCACGA AGAGGGTAGA GCTCATCTGT 
TGTGATCATA GTAACTACTG CAACCTCCCT GAGGGAGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997720.1
CDS	47..388
Translation	MLVLFLLGTVFLLCPYWGELHDPIKATEIMCYECKKYHLGLCYGVMTSCSLKHKQSCAVENFYILTRKGQSMYHYSKLSCMTSCEDINFLGFTKRVELICCDHSNYCNLPEGV

Target ORF information:

RefSeq Version	NM_212555.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prostate and testis expressed 2 (PATE2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212555.2

ORF Insert Sequence:

ATGCTTGTTC TCTTTCTCCT GGGCACAGTC TTTCTGCTCT GCCCATATTG GGGTGAACTT 
CATGACCCTA TAAAAGCGAC TGAAATAATG TGTTATGAAT GTAAAAAATA TCATCTTGGG 
TTATGCTATG GTGTCATGAC ATCCTGCTCC CTGAAGCATA AACAGTCCTG TGCAGTTGAG 
AACTTTTACA TCCTTACAAG GAAAGGGCAG AGCATGTATC ATTATTCAAA ACTGTCGTGT 
ATGACCAGCT GTGAGGACAT CAACTTCCTG GGGTTCACGA AGAGGGTAGA GCTCATCTGT 
TGTGATCATA GTAACTACTG CAACCTCCCT GAGGGAGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PATE2 ( NM_212555.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_997720.1 Homo sapiens prostate and testis expressed 2 (PATE2), mRNA.

Price & Availability↑

CloneID	OHu01287
Clone ID Related Accession (Same CDS sequence)	NM_212555.2 , NM_212555.3
Accession Version	NM_212555.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 342bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-24
Organism	Homo sapiens(human)
Product	prostate and testis expressed protein 2 precursor
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP003087.2 and AY358105.1. On May 17, 2019 this sequence version replaced NM_212555.2. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The extent of this RefSeq transcript is supported by transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY358105.1, SRR5189667.407643.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000358524.8/ ENSP00000351325.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGCTTGTTC TCTTTCTCCT GGGCACAGTC TTTCTGCTCT GCCCATATTG GGGTGAACTT 
CATGACCCTA TAAAAGCGAC TGAAATAATG TGTTATGAAT GTAAAAAATA TCATCTTGGG 
TTATGCTATG GTGTCATGAC ATCCTGCTCC CTGAAGCATA AACAGTCCTG TGCAGTTGAG 
AACTTTTACA TCCTTACAAG GAAAGGGCAG AGCATGTATC ATTATTCAAA ACTGTCGTGT 
ATGACCAGCT GTGAGGACAT CAACTTCCTG GGGTTCACGA AGAGGGTAGA GCTCATCTGT 
TGTGATCATA GTAACTACTG CAACCTCCCT GAGGGAGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_997720.1
CDS	56..397
Translation	MLVLFLLGTVFLLCPYWGELHDPIKATEIMCYECKKYHLGLCYGVMTSCSLKHKQSCAVENFYILTRKGQSMYHYSKLSCMTSCEDINFLGFTKRVELICCDHSNYCNLPEGV

Target ORF information:

RefSeq Version	NM_212555.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prostate and testis expressed 2 (PATE2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_212555.3

ORF Insert Sequence:

ATGCTTGTTC TCTTTCTCCT GGGCACAGTC TTTCTGCTCT GCCCATATTG GGGTGAACTT 
CATGACCCTA TAAAAGCGAC TGAAATAATG TGTTATGAAT GTAAAAAATA TCATCTTGGG 
TTATGCTATG GTGTCATGAC ATCCTGCTCC CTGAAGCATA AACAGTCCTG TGCAGTTGAG 
AACTTTTACA TCCTTACAAG GAAAGGGCAG AGCATGTATC ATTATTCAAA ACTGTCGTGT 
ATGACCAGCT GTGAGGACAT CAACTTCCTG GGGTTCACGA AGAGGGTAGA GCTCATCTGT 
TGTGATCATA GTAACTACTG CAACCTCCCT GAGGGAGTTT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Involvement of the prostate and testis expression (PATE)-like proteins in sperm-oocyte interaction.
Human reproduction (Oxford, England)27(5)1238-48(2012 May)
Margalit M,Yogev L,Yavetz H,Lehavi O,Hauser R,Botchan A,Barda S,Levitin F,Weiss M,Pastan I,Wreschner DH,Paz G,Kleiman SE

PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity.
The Journal of biological chemistry283(24)16928-39(2008 Jun)
Levitin F,Weiss M,Hahn Y,Stern O,Papke RL,Matusik R,Nandana SR,Ziv R,Pichinuk E,Salame S,Bera T,Vincent J,Lee B,Pastan I,Wreschner DH

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
Genome research13(10)2265-70(2003 Oct)
Clark HF,Gurney AL,Abaya E,Baker K,Baldwin D,Brush J,Chen J,Chow B,Chui C,Crowley C,Currell B,Deuel B,Dowd P,Eaton D,Foster J,Grimaldi C,Gu Q,Hass PE,Heldens S,Huang A,Kim HS,Klimowski L,Jin Y,Johnson S,Lee J,Lewis L,Liao D,Mark M,Robbie E,Sanchez C,Schoenfeld J,Seshagiri S,Simmons L,Singh J,Smith V,Stinson J,Vagts A,Vandlen R,Watanabe C,Wieand D,Woods K,Xie MH,Yansura D,Yi S,Yu G,Yuan J,Zhang M,Zhang Z,Goddard A,Wood WI,Godowski P,Gray A

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PATE2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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