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MYH6 cDNA ORF clone, Homo sapiens (human)

Gene Symbol MYH6
Entrez Gene ID 4624
Full Name myosin, heavy chain 6, cardiac muscle, alpha
Synonyms ASD3, CMD1EE, CMH14, MYHC, MYHCA, SSS3, alpha-MHC
General protein information
Preferred Names
myosin-6
Names
myosin-6
myHC-alpha
myosin heavy chain 6
myosin heavy chain, cardiac muscle alpha isoform
myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q12

Summary Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. [provided by RefSeq, Mar 2010]. lac of sum
Disorder MIM:

160710

Disorder Html: Cardiomyopathy, familial hypertrophic, 14, 613251 (3); Atrial septal

mRNA and Protein(s)

mRNA Protein Name
NM_002471 NP_002462 myosin-6



Homo sapiens (human) MYH6 NP_002462.2
Pan troglodytes (chimpanzee) MYH6 XP_003952494.1
Macaca mulatta (Rhesus monkey) MYH6 XP_001102827.2
Canis lupus familiaris (dog) MYH6 XP_003435121.2
Bos taurus (cattle) MYH6 XP_002690549.1
Mus musculus (house mouse) Myh6 NP_034986.1
Rattus norvegicus (Norway rat) Myh6 NP_058935.2
Gallus gallus (chicken) MYH15 NP_990097.1
Danio rerio (zebrafish) myh6 NP_942118.1
Xenopus (Silurana) tropicalis (western clawed frog) myh6 XP_004910815.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following MYH6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYH6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu18394 NM_002471 Homo sapiens myosin, heavy chain 6, cardiac muscle, alpha (MYH6), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 25 $923.30
$1319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu18394
Clone ID Related Accession (Same CDS sequence) NM_002471
Accession Version NM_002471.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 5820bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product myosin-6
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BX501231.1, DA566231.1, BC132667.1, D00943.1 and M21664.1. This sequence is a reference standard in the RefSeqGene project. On Mar 2, 2010 this sequence version replaced gi:156104907. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## CDS exon combination :: BC132667.1, D00943.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA2155550, SAMEA2159607 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
ATGACCGATG CCCAGATGGC TGACTTTGGG GCAGCGGCCC AGTACCTCCG CAAGTCAGAG 
AAGGAGCGTC TAGAGGCCCA GACCCGGCCC TTTGACATTC GCACTGAGTG CTTCGTGCCC
GATGACAAGG AAGAGTTTGT CAAAGCCAAG ATTTTGTCCC GGGAGGGAGG CAAGGTCATT
GCTGAAACCG AGAATGGGAA GACGGTGACT GTGAAGGAGG ACCAGGTGTT GCAGCAGAAC
CCACCCAAGT TCGACAAGAT TGAGGACATG GCCATGCTGA CCTTCCTGCA CGAGCCCGCG
GTGCTTTTCA ACCTCAAGGA GCGCTACGCG GCCTGGATGA TATATACCTA CTCGGGCCTC
TTCTGTGTCA CTGTCAACCC CTACAAGTGG CTGCCGGTGT ACAATGCCGA GGTGGTGGCC
GCCTACCGGG GCAAGAAGAG GAGTGAGGCC CCGCCCCACA TCTTCTCCAT CTCCGACAAC
GCCTATCAGT ACATGCTGAC AGATCGGGAG AACCAGTCCA TCCTCATCAC GGGAGAATCC
GGGGCGGGGA AGACTGTGAA CACCAAGCGT GTCATCCAGT ACTTTGCCAG CATTGCAGCC
ATAGGTGACC GTGGCAAGAA GGACAATGCC AATGCGAACA AGGGCACCCT GGAGGACCAG
ATCATCCAGG CCAACCCCGC TCTGGAGGCC TTCGGCAATG CCAAGACTGT CCGGAACGAC
AACTCCTCCC GCTTTGGGAA ATTCATTAGG ATCCACTTTG GGGCCACTGG AAAGCTGGCT
TCTGCAGACA TAGAGACCTA CCTGCTGGAG AAGTCCCGGG TGATCTTCCA GCTGAAAGCT
GAGAGAAACT ACCACATCTT CTACCAGATT CTGTCCAACA AGAAGCCGGA GTTGCTGGAC
ATGCTGCTGG TCACCAACAA TCCCTACGAC TACGCCTTCG TGTCTCAGGG AGAGGTGTCC
GTGGCCTCCA TTGATGACTC CGAGGAGCTC ATGGCCACCG ATAGTGCCTT TGACGTGCTG
GGCTTCACTT CAGAGGAGAA AGCTGGCGTC TACAAGCTGA CGGGAGCCAT CATGCACTAC
GGGAACATGA AGTTCAAGCA GAAGCAGCGG GAGGAGCAGG CGGAGCCAGA CGGCACCGAA
GATGCTGACA AGTCGGCCTA CCTCATGGGG CTGAACTCAG CTGACCTGCT CAAGGGGCTG
TGCCACCCTC GGGTGAAAGT GGGCAACGAG TATGTCACCA AGGGGCAGAG CGTGCAGCAG
GTGTACTACT CCATCGGGGC TCTGGCCAAG GCAGTGTATG AGAAGATGTT CAACTGGATG
GTGACGCGCA TCAACGCCAC CCTGGAGACC AAGCAGCCAC GCCAGTACTT CATAGGAGTC
CTGGACATCG CTGGCTTCGA GATCTTCGAC TTCAACAGCT TTGAGCAGCT CTGCATCAAC
TTCACCAACG AGAAGCTGCA GCAGTTCTTC AACCACCACA TGTTCGTGCT GGAGCAGGAG
GAGTACAAGA AGGAGGGCAT TGAGTGGACA TTCATTGACT TTGGCATGGA CCTGCAGGCC
TGCATTGACC TCATCGAGAA GCCCATGGGC ATCATGTCCA TCCTGGAGGA GGAGTGCATG
TTCCCCAAGG CCACTGACAT GACCTTCAAG GCCAAGCTGT ACGACAACCA CCTGGGCAAG
TCCAACAATT TCCAGAAGCC ACGCAACATC AAGGGGAAGC AGGAAGCCCA CTTCTCCCTG
ATCCACTACG CCGGCACTGT GGACTACAAC ATCCTGGGCT GGCTGGAAAA AAACAAGGAT
CCTCTCAACG AGACTGTTGT GGCCCTGTAC CAGAAGTCCT CCCTCAAGCT CATGGCCACT
CTCTTCTCCT CCTACGCAAC TGCCGATACT GGGGACAGTG GTAAAAGCAA AGGAGGCAAG
AAAAAGGGCT CATCCTTCCA GACGGTGTCG GCTCTCCACC GGGAAAATCT CAACAAGCTA
ATGACCAACC TGAGGACCAC CCATCCTCAC TTTGTGCGTT GCATCATCCC CAATGAGCGG
AAGGCTCCAG GGGTGATGGA CAACCCCCTG GTCATGCACC AGCTGCGCTG CAATGGCGTG
CTGGAGGGCA TCCGCATCTG CAGGAAGGGC TTCCCCAACC GCATCCTCTA CGGGGACTTC
CGGCAGAGGT ATCGCATCCT GAACCCAGTG GCCATCCCTG AGGGACAGTT CATTGATAGC
AGGAAGGGGA CAGAGAAGCT GCTCAGCTCT CTGGACATTG ATCACAACCA GTACAAGTTT
GGCCACACCA AGGTGTTCTT CAAGGCAGGG CTGCTTGGGC TGCTGGAGGA GATGCGGGAT
GAGAGGCTGA GCCGCATCAT CACGCGCATG CAGGCCCAAG CCCGGGGCCA GCTCATGCGC
ATTGAGTTCA AGAAGATAGT GGAACGCAGG GATGCCCTGC TGGTAATCCA GTGGAACATT
CGGGCCTTCA TGGGGGTCAA GAATTGGCCC TGGATGAAGC TCTACTTCAA GATCAAGCCG
CTGCTGAAGA GCGCAGAGAC GGAGAAGGAG ATGGCCACCA TGAAGGAAGA GTTCGGGCGC
ATCAAAGAGA CGCTGGAGAA GTCCGAGGCT CGCCGCAAGG AGCTGGAGGA GAAGATGGTG
TCCCTGCTGC AGGAGAAGAA TGACCTGCAG CTCCAAGTGC AGGCGGAACA AGACAACCTC
AATGATGCTG AGGAGCGCTG CGACCAGCTG ATCAAAAACA AGATTCAGCT GGAGGCCAAA
GTAAAGGAGA TGAATGAGAG GCTGGAGGAT GAGGAGGAGA TGAACGCGGA GCTCACTGCC
AAGAAGCGCA AGCTGGAAGA CGAGTGCTCA GAGCTCAAGA AGGACATTGA TGACCTGGAG
CTGACACTGG CCAAGGTGGA GAAGGAGAAG CATGCAACAG AGAACAAGGT GAAGAACCTA
ACAGAGGAGA TGGCTGGGCT GGATGAAATC ATCGCTAAGC TGACCAAGGA GAAGAAAGCT
CTACAAGAGG CCCATCAGCA GGCCCTGGAT GACCTTCAGG TTGAGGAAGA CAAGGTCAAC
AGCCTGTCCA AGTCTAAGGT CAAGCTGGAG CAGCAGGTGG ATGATCTGGA GGGATCCCTA
GAGCAAGAGA AGAAGGTGCG CATGGACCTG GAGCGAGCAA AGCGGAAACT GGAGGGCGAC
CTGAAGCTGA CCCAGGAGAG CATCATGGAC CTGGAAAATG ATAAACTGCA GCTGGAAGAA
AAGCTTAAGA AGAAGGAGTT TGACATTAAT CAGCAGAACA GTAAGATTGA GGATGAGCAG
GTGCTGGCCC TTCAACTACA GAAGAAACTG AAGGAAAACC AGGCACGCAT CGAGGAGCTG
GAGGAGGAGC TGGAGGCCGA GCGCACCGCC AGGGCTAAGG TGGAGAAGCT GCGCTCAGAC
CTGTCTCGGG AGCTGGAGGA GATCAGCGAG CGGCTGGAAG AGGCCGGCGG GGCCACGTCC
GTGCAGATCG AGATGAACAA GAAGCGCGAG GCCGAGTTCC AGAAGATGCG GCGGGACCTG
GAGGAGGCCA CGCTGCAGCA CGAGGCCACT GCCGCGGCCC TGCGCAAGAA GCACGCCGAC
AGCGTGGCCG AGCTGGGCGA GCAGATCGAC AACCTGCAGC GGGTGAAGCA GAAGCTGGAG
AAGGAGAAGA GCGAGTTCAA GCTGGAGCTG GATGACGTCA CCTCCAACAT GGAGCAGATC
ATCAAGGCCA AGGCAAACCT GGAGAAAGTG TCTCGGACGC TGGAGGACCA GGCCAATGAG
TACCGCGTGA AGCTAGAAGA GGCCCAACGC TCCCTCAATG ATTTCACCAC CCAGCGAGCC
AAGCTGCAGA CCGAGAATGG AGAGTTGGCC CGGCAGCTAG AGGAAAAGGA GGCGCTAATC
TCGCAGCTGA CCCGGGGGAA GCTCTCTTAT ACCCAGCAAA TGGAGGACCT CAAAAGGCAG
CTGGAGGAGG AGGGCAAGGC GAAGAACGCC CTGGCCCATG CACTGCAGTC GGCCCGGCAT
GACTGCGACC TGCTGCGGGA GCAGTACGAG GAGGAGACAG AGGCCAAGGC CGAGCTGCAG
CGCGTCCTGT CCAAGGCCAA CTCGGAGGTG GCCCAGTGGA GGACCAAGTA TGAGACGGAC
GCCATTCAGC GGACTGAGGA GCTCGAAGAG GCCAAAAAGA AGCTGGCCCA GCGGCTGCAG
GATGCCGAGG AGGCCGTGGA GGCTGTTAAT GCCAAGTGCT CCTCACTGGA GAAGACCAAG
CACCGGCTAC AGAATGAGAT AGAGGACTTG ATGGTGGACG TAGAGCGCTC CAATGCTGCT
GCTGCAGCCC TGGACAAGAA GCAGAGAAAC TTTGACAAGA TCCTGGCCGA GTGGAAGCAG
AAGTATGAGG AGTCGCAGTC TGAGCTGGAG TCCTCACAGA AGGAGGCTCG CTCCCTCAGC
ACAGAGCTCT TCAAGCTCAA GAACGCCTAC GAGGAGTCCC TGGAGCACCT AGAGACCTTC
AAGCGGGAGA ACAAGAACCT TCAGGAGGAA ATCTCGGACC TTACTGAGCA GCTAGGAGAA
GGAGGAAAGA ATGTGCATGA GCTGGAGAAG GTCCGCAAAC AGCTGGAGGT GGAGAAGCTG
GAGCTGCAGT CAGCCCTGGA GGAGGCAGAG GCCTCCCTGG AGCACGAGGA GGGCAAGATC
CTCCGGGCCC AGCTAGAGTT CAACCAGATC AAGGCAGAGA TCGAGCGGAA GCTGGCAGAG
AAGGACGAGG AGATGGAACA GGCCAAGCGC AACCACCAGC GGGTGGTGGA CTCGCTGCAG
ACCTCCCTGG ATGCAGAGAC ACGCAGCCGC AACGAGGTCC TGAGGGTGAA GAAGAAGATG
GAAGGAGACC TCAATGAGAT GGAGATCCAG CTCAGCCACG CCAACCGCAT GGCTGCCGAG
GCCCAGAAGC AAGTCAAGAG CCTCCAGAGC TTGCTGAAGG ACACCCAGAT CCAGCTGGAC
GATGCGGTCC GTGCCAACGA CGACCTGAAG GAGAACATCG CCATCGTGGA GCGGCGCAAC
AACCTGCTGC AGGCTGAGCT GGAGGAGCTG CGTGCCGTGG TGGAGCAGAC AGAGCGGTCC
CGGAAGCTGG CGGAGCAGGA GCTGATTGAG ACCAGCGAGC GGGTGCAGCT GCTGCATTCC
CAGAACACCA GCCTCATCAA CCAGAAGAAG AAGATGGAGT CGGATCTGAC CCAGCTCCAG
TCGGAAGTGG AGGAGGCAGT GCAGGAGTGC AGAAACGCCG AGGAGAAGGC CAAGAAGGCC
ATCACGGATG CCGCCATGAT GGCAGAGGAG CTGAAGAAGG AGCAGGACAC CAGCGCCCAC
CTGGAGCGCA TGAAGAAGAA CATGGAGCAG ACCATTAAGG ACCTGCAGCA CCGGCTGGAC
GAGGCCGAGC AGATCGCCCT CAAGGGAGGC AAGAAGCAGC TGCAGAAGCT GGAAGCGCGG
GTGCGGGAGC TGGAGGGTGA GCTGGAGGCC GAGCAGAAGC GCAACGCAGA GTCGGTGAAG
GGCATGAGGA AGAGCGAGCG GCGCATCAAG GAGCTCACCT ACCAGACAGA GGAAGACAAA
AAGAACCTGC TGCGGCTACA GGACCTGGTG GACAAGCTGC AACTGAAGGT CAAGGCCTAC
AAGCGCCAGG CCGAGGAGGC GGAGGAGCAA GCCAACACCA ACCTGTCCAA GTTCCGCAAG
GTGCAGCATG AGCTGGATGA GGCAGAGGAG CGGGCGGACA TCGCTGAGTC CCAGGTCAAC
AAGCTTCGAG CCAAGAGCCG TGACATTGGT GCCAAGCAAA AAATGCACGA TGAGGAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002462.2
CDS72..5891
Misc Feature(1)171..296(+)
Misc Feature(2)309..2411(+)
Misc Feature(3)366..2375(+)
Misc Feature(4)447..1472(+)
Misc Feature(5)447..473(+)
Misc Feature(6)603..626(+)
Misc Feature(7)771..803(+)
Misc Feature(8)1455..1472(+)
Misc Feature(9)1542..1613(+)
Misc Feature(10)2040..2108(+)
Misc Feature(11)2166..2195(+)
Misc Feature(12)2202..2375(+)
Misc Feature(13)2346..2390(+)
Misc Feature(14)2616..3206(+)
Misc Feature(15)2712..3200(+)
Misc Feature(16)3279..5855(+)
Misc Feature(17)3471..3956(+)
Misc Feature(18)3960..>4298(+)
Misc Feature(19)3960..4295(+)
Misc Feature(20)5112..5480(+)
Exon (1)1..25
Gene:MYH6
Gene Synonym:
Exon (2)26..58
Gene:MYH6
Gene Synonym:
Exon (3)59..272
Gene:MYH6
Gene Synonym:
Exon (4)273..416
Gene:MYH6
Gene Synonym:
Exon (5)417..573
Gene:MYH6
Gene Synonym:
Exon (6)574..601
Gene:MYH6
Gene Synonym:
Exon (7)602..713
Gene:MYH6
Gene Synonym:
Exon (8)714..806
Gene:MYH6
Gene Synonym:
Exon (9)807..870
Gene:MYH6
Gene Synonym:
Exon (10)871..969
Gene:MYH6
Gene Synonym:
Exon (11)970..1073
Gene:MYH6
Gene Synonym:
Exon (12)1074..1212
Gene:MYH6
Gene Synonym:
Exon (13)1213..1481
Gene:MYH6
Gene Synonym:
Exon (14)1482..1652
Gene:MYH6
Gene Synonym:
Exon (15)1653..1962
Gene:MYH6
Gene Synonym:
Exon (16)1963..2033
Gene:MYH6
Gene Synonym:
Exon (17)2034..2121
Gene:MYH6
Gene Synonym:
Exon (18)2122..2239
Gene:MYH6
Gene Synonym:
Exon (19)2240..2363
Gene:MYH6
Gene Synonym:
Exon (20)2364..2500
Gene:MYH6
Gene Synonym:
Exon (21)2501..2756
Gene:MYH6
Gene Synonym:
Exon (22)2757..2999
Gene:MYH6
Gene Synonym:
Exon (23)3000..3176
Gene:MYH6
Gene Synonym:
Exon (24)3177..3322
Gene:MYH6
Gene Synonym:
Exon (25)3323..3413
Gene:MYH6
Gene Synonym:
Exon (26)3414..3803
Gene:MYH6
Gene Synonym:
Exon (27)3804..3930
Gene:MYH6
Gene Synonym:
Exon (28)3931..4049
Gene:MYH6
Gene Synonym:
Exon (29)4050..4246
Gene:MYH6
Gene Synonym:
Exon (30)4247..4430
Gene:MYH6
Gene Synonym:
Exon (31)4431..4596
Gene:MYH6
Gene Synonym:
Exon (32)4597..4721
Gene:MYH6
Gene Synonym:
Exon (33)4722..5030
Gene:MYH6
Gene Synonym:
Exon (34)5031..5234
Gene:MYH6
Gene Synonym:
Exon (35)5235..5360
Gene:MYH6
Gene Synonym:
Exon (36)5361..5636
Gene:MYH6
Gene Synonym:
Exon (37)5637..5732
Gene:MYH6
Gene Synonym:
Exon (38)5733..5867
Gene:MYH6
Gene Synonym:
Exon (39)5868..5941
Gene:MYH6
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002471
Organism Homo sapiens (human)
Definition Homo sapiens myosin, heavy chain 6, cardiac muscle, alpha (MYH6), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002471

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
3481
3541
3601
3661
3721
3781
3841
3901
3961
4021
4081
4141
4201
4261
4321
4381
4441
4501
4561
4621
4681
4741
4801
4861
4921
4981
5041
5101
5161
5221
5281
5341
5401
5461
5521
5581
5641
5701
5761
ATGACCGATG CCCAGATGGC TGACTTTGGG GCAGCGGCCC AGTACCTCCG CAAGTCAGAG 
AAGGAGCGTC TAGAGGCCCA GACCCGGCCC TTTGACATTC GCACTGAGTG CTTCGTGCCC
GATGACAAGG AAGAGTTTGT CAAAGCCAAG ATTTTGTCCC GGGAGGGAGG CAAGGTCATT
GCTGAAACCG AGAATGGGAA GACGGTGACT GTGAAGGAGG ACCAGGTGTT GCAGCAGAAC
CCACCCAAGT TCGACAAGAT TGAGGACATG GCCATGCTGA CCTTCCTGCA CGAGCCCGCG
GTGCTTTTCA ACCTCAAGGA GCGCTACGCG GCCTGGATGA TATATACCTA CTCGGGCCTC
TTCTGTGTCA CTGTCAACCC CTACAAGTGG CTGCCGGTGT ACAATGCCGA GGTGGTGGCC
GCCTACCGGG GCAAGAAGAG GAGTGAGGCC CCGCCCCACA TCTTCTCCAT CTCCGACAAC
GCCTATCAGT ACATGCTGAC AGATCGGGAG AACCAGTCCA TCCTCATCAC GGGAGAATCC
GGGGCGGGGA AGACTGTGAA CACCAAGCGT GTCATCCAGT ACTTTGCCAG CATTGCAGCC
ATAGGTGACC GTGGCAAGAA GGACAATGCC AATGCGAACA AGGGCACCCT GGAGGACCAG
ATCATCCAGG CCAACCCCGC TCTGGAGGCC TTCGGCAATG CCAAGACTGT CCGGAACGAC
AACTCCTCCC GCTTTGGGAA ATTCATTAGG ATCCACTTTG GGGCCACTGG AAAGCTGGCT
TCTGCAGACA TAGAGACCTA CCTGCTGGAG AAGTCCCGGG TGATCTTCCA GCTGAAAGCT
GAGAGAAACT ACCACATCTT CTACCAGATT CTGTCCAACA AGAAGCCGGA GTTGCTGGAC
ATGCTGCTGG TCACCAACAA TCCCTACGAC TACGCCTTCG TGTCTCAGGG AGAGGTGTCC
GTGGCCTCCA TTGATGACTC CGAGGAGCTC ATGGCCACCG ATAGTGCCTT TGACGTGCTG
GGCTTCACTT CAGAGGAGAA AGCTGGCGTC TACAAGCTGA CGGGAGCCAT CATGCACTAC
GGGAACATGA AGTTCAAGCA GAAGCAGCGG GAGGAGCAGG CGGAGCCAGA CGGCACCGAA
GATGCTGACA AGTCGGCCTA CCTCATGGGG CTGAACTCAG CTGACCTGCT CAAGGGGCTG
TGCCACCCTC GGGTGAAAGT GGGCAACGAG TATGTCACCA AGGGGCAGAG CGTGCAGCAG
GTGTACTACT CCATCGGGGC TCTGGCCAAG GCAGTGTATG AGAAGATGTT CAACTGGATG
GTGACGCGCA TCAACGCCAC CCTGGAGACC AAGCAGCCAC GCCAGTACTT CATAGGAGTC
CTGGACATCG CTGGCTTCGA GATCTTCGAC TTCAACAGCT TTGAGCAGCT CTGCATCAAC
TTCACCAACG AGAAGCTGCA GCAGTTCTTC AACCACCACA TGTTCGTGCT GGAGCAGGAG
GAGTACAAGA AGGAGGGCAT TGAGTGGACA TTCATTGACT TTGGCATGGA CCTGCAGGCC
TGCATTGACC TCATCGAGAA GCCCATGGGC ATCATGTCCA TCCTGGAGGA GGAGTGCATG
TTCCCCAAGG CCACTGACAT GACCTTCAAG GCCAAGCTGT ACGACAACCA CCTGGGCAAG
TCCAACAATT TCCAGAAGCC ACGCAACATC AAGGGGAAGC AGGAAGCCCA CTTCTCCCTG
ATCCACTACG CCGGCACTGT GGACTACAAC ATCCTGGGCT GGCTGGAAAA AAACAAGGAT
CCTCTCAACG AGACTGTTGT GGCCCTGTAC CAGAAGTCCT CCCTCAAGCT CATGGCCACT
CTCTTCTCCT CCTACGCAAC TGCCGATACT GGGGACAGTG GTAAAAGCAA AGGAGGCAAG
AAAAAGGGCT CATCCTTCCA GACGGTGTCG GCTCTCCACC GGGAAAATCT CAACAAGCTA
ATGACCAACC TGAGGACCAC CCATCCTCAC TTTGTGCGTT GCATCATCCC CAATGAGCGG
AAGGCTCCAG GGGTGATGGA CAACCCCCTG GTCATGCACC AGCTGCGCTG CAATGGCGTG
CTGGAGGGCA TCCGCATCTG CAGGAAGGGC TTCCCCAACC GCATCCTCTA CGGGGACTTC
CGGCAGAGGT ATCGCATCCT GAACCCAGTG GCCATCCCTG AGGGACAGTT CATTGATAGC
AGGAAGGGGA CAGAGAAGCT GCTCAGCTCT CTGGACATTG ATCACAACCA GTACAAGTTT
GGCCACACCA AGGTGTTCTT CAAGGCAGGG CTGCTTGGGC TGCTGGAGGA GATGCGGGAT
GAGAGGCTGA GCCGCATCAT CACGCGCATG CAGGCCCAAG CCCGGGGCCA GCTCATGCGC
ATTGAGTTCA AGAAGATAGT GGAACGCAGG GATGCCCTGC TGGTAATCCA GTGGAACATT
CGGGCCTTCA TGGGGGTCAA GAATTGGCCC TGGATGAAGC TCTACTTCAA GATCAAGCCG
CTGCTGAAGA GCGCAGAGAC GGAGAAGGAG ATGGCCACCA TGAAGGAAGA GTTCGGGCGC
ATCAAAGAGA CGCTGGAGAA GTCCGAGGCT CGCCGCAAGG AGCTGGAGGA GAAGATGGTG
TCCCTGCTGC AGGAGAAGAA TGACCTGCAG CTCCAAGTGC AGGCGGAACA AGACAACCTC
AATGATGCTG AGGAGCGCTG CGACCAGCTG ATCAAAAACA AGATTCAGCT GGAGGCCAAA
GTAAAGGAGA TGAATGAGAG GCTGGAGGAT GAGGAGGAGA TGAACGCGGA GCTCACTGCC
AAGAAGCGCA AGCTGGAAGA CGAGTGCTCA GAGCTCAAGA AGGACATTGA TGACCTGGAG
CTGACACTGG CCAAGGTGGA GAAGGAGAAG CATGCAACAG AGAACAAGGT GAAGAACCTA
ACAGAGGAGA TGGCTGGGCT GGATGAAATC ATCGCTAAGC TGACCAAGGA GAAGAAAGCT
CTACAAGAGG CCCATCAGCA GGCCCTGGAT GACCTTCAGG TTGAGGAAGA CAAGGTCAAC
AGCCTGTCCA AGTCTAAGGT CAAGCTGGAG CAGCAGGTGG ATGATCTGGA GGGATCCCTA
GAGCAAGAGA AGAAGGTGCG CATGGACCTG GAGCGAGCAA AGCGGAAACT GGAGGGCGAC
CTGAAGCTGA CCCAGGAGAG CATCATGGAC CTGGAAAATG ATAAACTGCA GCTGGAAGAA
AAGCTTAAGA AGAAGGAGTT TGACATTAAT CAGCAGAACA GTAAGATTGA GGATGAGCAG
GTGCTGGCCC TTCAACTACA GAAGAAACTG AAGGAAAACC AGGCACGCAT CGAGGAGCTG
GAGGAGGAGC TGGAGGCCGA GCGCACCGCC AGGGCTAAGG TGGAGAAGCT GCGCTCAGAC
CTGTCTCGGG AGCTGGAGGA GATCAGCGAG CGGCTGGAAG AGGCCGGCGG GGCCACGTCC
GTGCAGATCG AGATGAACAA GAAGCGCGAG GCCGAGTTCC AGAAGATGCG GCGGGACCTG
GAGGAGGCCA CGCTGCAGCA CGAGGCCACT GCCGCGGCCC TGCGCAAGAA GCACGCCGAC
AGCGTGGCCG AGCTGGGCGA GCAGATCGAC AACCTGCAGC GGGTGAAGCA GAAGCTGGAG
AAGGAGAAGA GCGAGTTCAA GCTGGAGCTG GATGACGTCA CCTCCAACAT GGAGCAGATC
ATCAAGGCCA AGGCAAACCT GGAGAAAGTG TCTCGGACGC TGGAGGACCA GGCCAATGAG
TACCGCGTGA AGCTAGAAGA GGCCCAACGC TCCCTCAATG ATTTCACCAC CCAGCGAGCC
AAGCTGCAGA CCGAGAATGG AGAGTTGGCC CGGCAGCTAG AGGAAAAGGA GGCGCTAATC
TCGCAGCTGA CCCGGGGGAA GCTCTCTTAT ACCCAGCAAA TGGAGGACCT CAAAAGGCAG
CTGGAGGAGG AGGGCAAGGC GAAGAACGCC CTGGCCCATG CACTGCAGTC GGCCCGGCAT
GACTGCGACC TGCTGCGGGA GCAGTACGAG GAGGAGACAG AGGCCAAGGC CGAGCTGCAG
CGCGTCCTGT CCAAGGCCAA CTCGGAGGTG GCCCAGTGGA GGACCAAGTA TGAGACGGAC
GCCATTCAGC GGACTGAGGA GCTCGAAGAG GCCAAAAAGA AGCTGGCCCA GCGGCTGCAG
GATGCCGAGG AGGCCGTGGA GGCTGTTAAT GCCAAGTGCT CCTCACTGGA GAAGACCAAG
CACCGGCTAC AGAATGAGAT AGAGGACTTG ATGGTGGACG TAGAGCGCTC CAATGCTGCT
GCTGCAGCCC TGGACAAGAA GCAGAGAAAC TTTGACAAGA TCCTGGCCGA GTGGAAGCAG
AAGTATGAGG AGTCGCAGTC TGAGCTGGAG TCCTCACAGA AGGAGGCTCG CTCCCTCAGC
ACAGAGCTCT TCAAGCTCAA GAACGCCTAC GAGGAGTCCC TGGAGCACCT AGAGACCTTC
AAGCGGGAGA ACAAGAACCT TCAGGAGGAA ATCTCGGACC TTACTGAGCA GCTAGGAGAA
GGAGGAAAGA ATGTGCATGA GCTGGAGAAG GTCCGCAAAC AGCTGGAGGT GGAGAAGCTG
GAGCTGCAGT CAGCCCTGGA GGAGGCAGAG GCCTCCCTGG AGCACGAGGA GGGCAAGATC
CTCCGGGCCC AGCTAGAGTT CAACCAGATC AAGGCAGAGA TCGAGCGGAA GCTGGCAGAG
AAGGACGAGG AGATGGAACA GGCCAAGCGC AACCACCAGC GGGTGGTGGA CTCGCTGCAG
ACCTCCCTGG ATGCAGAGAC ACGCAGCCGC AACGAGGTCC TGAGGGTGAA GAAGAAGATG
GAAGGAGACC TCAATGAGAT GGAGATCCAG CTCAGCCACG CCAACCGCAT GGCTGCCGAG
GCCCAGAAGC AAGTCAAGAG CCTCCAGAGC TTGCTGAAGG ACACCCAGAT CCAGCTGGAC
GATGCGGTCC GTGCCAACGA CGACCTGAAG GAGAACATCG CCATCGTGGA GCGGCGCAAC
AACCTGCTGC AGGCTGAGCT GGAGGAGCTG CGTGCCGTGG TGGAGCAGAC AGAGCGGTCC
CGGAAGCTGG CGGAGCAGGA GCTGATTGAG ACCAGCGAGC GGGTGCAGCT GCTGCATTCC
CAGAACACCA GCCTCATCAA CCAGAAGAAG AAGATGGAGT CGGATCTGAC CCAGCTCCAG
TCGGAAGTGG AGGAGGCAGT GCAGGAGTGC AGAAACGCCG AGGAGAAGGC CAAGAAGGCC
ATCACGGATG CCGCCATGAT GGCAGAGGAG CTGAAGAAGG AGCAGGACAC CAGCGCCCAC
CTGGAGCGCA TGAAGAAGAA CATGGAGCAG ACCATTAAGG ACCTGCAGCA CCGGCTGGAC
GAGGCCGAGC AGATCGCCCT CAAGGGAGGC AAGAAGCAGC TGCAGAAGCT GGAAGCGCGG
GTGCGGGAGC TGGAGGGTGA GCTGGAGGCC GAGCAGAAGC GCAACGCAGA GTCGGTGAAG
GGCATGAGGA AGAGCGAGCG GCGCATCAAG GAGCTCACCT ACCAGACAGA GGAAGACAAA
AAGAACCTGC TGCGGCTACA GGACCTGGTG GACAAGCTGC AACTGAAGGT CAAGGCCTAC
AAGCGCCAGG CCGAGGAGGC GGAGGAGCAA GCCAACACCA ACCTGTCCAA GTTCCGCAAG
GTGCAGCATG AGCTGGATGA GGCAGAGGAG CGGGCGGACA TCGCTGAGTC CCAGGTCAAC
AAGCTTCGAG CCAAGAGCCG TGACATTGGT GCCAAGCAAA AAATGCACGA TGAGGAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

All-atom molecular dynamics simulations of actin-myosin interactions: a comparative study of cardiac alpha myosin, beta myosin, and fast skeletal muscle myosin
Biochemistry 52 (47), 8393-8405 (2013)
Li M and Zheng W.


book

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
Nat. Genet. 45 (6), 621-631 (2013)
den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segre AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dorr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, Kaab S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, Muller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp S, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Jarvelin MR, Jula A, Kahonen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimaki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widen E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L, Erdmann J, Thompson JR, Pfeufer A, Sotoodehnia N, Newton-Cheh C, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ and Loos RJ.


book

Common genetic variation near the connexin-43 gene is associated with resting heart rate in African Americans: a genome-wide association study of 13,372 participants
Heart Rhythm 10 (3), 401-408 (2013)
Deo R, Nalls MA, Avery CL, Smith JG, Evans DS, Keller MF, Butler AM, Buxbaum SG, Li G, Miguel Quibrera P, Smith EN, Tanaka T, Akylbekova EL, Alonso A, Arking DE, Benjamin EJ, Berenson GS, Bis JC, Chen LY, Chen W, Cummings SR, Ellinor PT, Evans MK, Ferrucci L, Fox ER, Heckbert SR, Heiss G, Hsueh WC, Kerr KF, Limacher MC, Liu Y, Lubitz SA, Magnani JW, Mehra R, Marcus GM, Murray SS, Newman AB, Njajou O, North KE, Paltoo DN, Psaty BM, Redline SS, Reiner AP, Robinson JG, Rotter JI, Samdarshi TE, Schnabel RB, Schork NJ, Singleton AB, Siscovick D, Soliman EZ, Sotoodehnia N, Srinivasan SR, Taylor HA, Trevisan M, Zhang Z, Zonderman AB, Newton-Cheh C and Whitsel EA.


book

MYH9-related disorders: report on a patient of Greek origin presenting with macroscopic hematuria and presenile cataract, caused by an R1165C mutation
J. Pediatr. Hematol. Oncol. 34 (6), 412-415 (2012)
Economou M, Batzios SP, Pecci A, Printza N, Savoia A, Barozzi S, Theodoridou S, Teli A, Psillas G and Zafeiriou DI.


book

Hypertrophic Cardiomyopathy Overview
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Cirino,A.L. and Ho,C.


book

Dilated Cardiomyopathy Overview
(in) Pagon RA, Adam MP, Ardinger HH, Bird TD, Dolan CR, Fong CT, Smith RJH and Stephens K (Eds.); GENEREVIEWS(R); (1993)
Hershberger,R.E. and Morales,A.


book

Complete sequence of human cardiac alpha-myosin heavy chain gene and amino acid comparison to other myosins based on structural and functional differences
Am. J. Med. Genet. 41 (4), 537-547 (1991)
Matsuoka R, Beisel KW, Furutani M, Arai S and Takao A.


book

Determination of the 5' exon structure of the human cardiac alpha-myosin heavy chain gene
Biochem. Biophys. Res. Commun. 179 (3), 1255-1258 (1991)
Brand NJ, Dabhade N, Yacoub M and Barton PJ.


book

Nucleotide sequence of chimpanzee Fc and hinge regions
Mol. Immunol. 28 (4-5), 319-322 (1991)
Ehrlich PH, Moustafa ZA and Ostberg L.


book

A locus for familial hypertrophic cardiomyopathy is closely linked to the cardiac myosin heavy chain genes, CRI-L436, and CRI-L329 on chromosome 14 at q11-q12
Am. J. Hum. Genet. 47 (3), 389-394 (1990)
Solomon SD, Geisterfer-Lowrance AA, Vosberg HP, Hiller G, Jarcho JA, Morton CC, McBride WO, Mitchell AL, Bale AE and McKenna WJ.


 
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