Gene Symbol | NDST4 |
Entrez Gene ID | 64579 |
Full Name | N-deacetylase and N-sulfotransferase 4 |
Synonyms | N-HSST,N-HSST 4,NDST-4,NHSST4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » NDST4 cDNA ORF clone
gRNAs
Gene Symbol | NDST4 |
Entrez Gene ID | 64579 |
Full Name | N-deacetylase and N-sulfotransferase 4 |
Synonyms | N-HSST,N-HSST 4,NDST-4,NHSST4 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_022569.1 | NP_072091.1 | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 |
XM_017008545.2 | XP_016864034.1 | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 isoform X1 |
NM_022569.3 | NP_072091.1 | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 |
XM_017008546.1 | XP_016864035.1 | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 isoform X1 |
XM_017008545.1 | XP_016864034.1 | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 isoform X1 |
NM_022569.2 | NP_072091.1 | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 |
NDST4 | XP_001097335.1 | |
Rattus norvegicus (Norway rat) | Ndst4 | NP_001178778.1 |
Gallus gallus (chicken) | NDST4 | XP_420638.2 |
Xenopus tropicalis (tropical clawed frog) | ndst4 | XP_002934293.1 |
Homo sapiens (human) | NDST4 | NP_072091.1 |
Mus musculus (house mouse) | Ndst4 | NP_072087.2 |
Bos taurus (cattle) | NDST4 | NP_001179602.1 |
Pan troglodytes (chimpanzee) | NDST4 | XP_526668.1 |
Canis lupus familiaris (dog) | NDST4 | XP_005639369.1 |
Danio rerio (zebrafish) | ndst3 | XP_002660470.1 |
Characterization of heparan sulfate N-deacetylase/N-sulfotransferase isoform 4 using synthetic oligosaccharide substrates.
Li YJ, Yin FX, Zhang XK, Yu J, Zheng S, Song XL, Wang FS, Sheng JZ
Biochimica et biophysica acta1862(3)547-556(2017 Nov)
Genome-wide association studies of maximum number of drinks.
Pan Y, Luo X, Liu X, Wu LY, Zhang Q, Wang L, Wang W, Zuo L, Wang KS
Journal of psychiatric research47(11)1717-24(2013 Nov)
A genome-wide association study (GWAS) for bronchopulmonary dysplasia.
Wang H, St Julien KR, Stevenson DK, Hoffmann TJ, Witte JS, Lazzeroni LC, Krasnow MA, Quaintance CC, Oehlert JW, Jelliffe-Pawlowski LL, Gould JB, Shaw GM, O'Brodovich HM
Pediatrics132(2)290-7(2013 Aug)
NDST4 is a novel candidate tumor suppressor gene at chromosome 4q26 and its genetic loss predicts adverse prognosis in colorectal cancer.
Tzeng ST, Tsai MH, Chen CL, Lee JX, Jao TM, Yu SL, Yen SJ, Yang YC
PloS one8(6)e67040(2013)
Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels.
Qi Q, Menzaghi C, Smith S, Liang L, de Rekeneire N, Garcia ME, Lohman KK, Miljkovic I, Strotmeyer ES, Cummings SR, Kanaya AM, Tylavsky FA, Satterfield S, Ding J, Rimm EB, Trischitta V, Hu FB, Liu Y, Qi L
Human molecular genetics21(21)4774-80(2012 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The rs12108602 near NDST4 showed significant associations with MaxDrinks.
Title: Genome-wide association studies of maximum number of drinks.
NDST4 gene is a novel candidate tumor suppressor gene in human cancer.
Title: NDST4 is a novel candidate tumor suppressor gene at chromosome 4q26 and its genetic loss predicts adverse prognosis in colorectal cancer.
Our results suggest that genetic variants in TYW3/CRYZ and NDST4 loci may be involved in the regulation of circulating resistin levels
Title: Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Observational study of gene-disease association. (HuGE Navigator)
Title: A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
The following NDST4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NDST4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu95377 | |
Clone ID Related Accession (Same CDS sequence) | XM_017008545.2 , XM_017008546.1 , XM_017008545.1 | |
Accession Version | XM_017008545.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017008545.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGAGCC ACATGCAGCC CCACCTCTTC CACAACGAGT CATCTTTAGT AGAGCAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016864034.1 |
CDS | 850..2331 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTGGAGCC ACATGCAGCC CCACCTCTTC CACAACGAGT CATCTTTAGT AGAGCAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu95377 | |
Clone ID Related Accession (Same CDS sequence) | XM_017008545.2 , XM_017008546.1 , XM_017008545.1 | |
Accession Version | XM_017008546.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGAGCC ACATGCAGCC CCACCTCTTC CACAACGAGT CATCTTTAGT AGAGCAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016864035.1 |
CDS | 121..1602 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTGGAGCC ACATGCAGCC CCACCTCTTC CACAACGAGT CATCTTTAGT AGAGCAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu95377 | |
Clone ID Related Accession (Same CDS sequence) | XM_017008545.2 , XM_017008546.1 , XM_017008545.1 | |
Accession Version | XM_017008545.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1482bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGGAGCC ACATGCAGCC CCACCTCTTC CACAACGAGT CATCTTTAGT AGAGCAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016864034.1 |
CDS | 815..2296 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTGGAGCC ACATGCAGCC CCACCTCTTC CACAACGAGT CATCTTTAGT AGAGCAGATG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25508 | |
Clone ID Related Accession (Same CDS sequence) | NM_022569.1 , NM_022569.3 , NM_022569.2 | |
Accession Version | NM_022569.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2619bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-14 | |
Organism | Homo sapiens(Human) | |
Product | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 | |
Comment |
1 | ATGAATCTTA TTGTGAAACT TCGGAGAAGT TTTCGAACAT TGATTGTTCT CTTAGCTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_072091.1 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAATCTTA TTGTGAAACT TCGGAGAAGT TTTCGAACAT TGATTGTTCT CTTAGCTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25508 | |
Clone ID Related Accession (Same CDS sequence) | NM_022569.1 , NM_022569.3 , NM_022569.2 | |
Accession Version | NM_022569.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2619bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-01 | |
Organism | Homo sapiens(human) | |
Product | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB036429.1, BC012326.1, AK289670.1 and AC110777.3. On May 17, 2019 this sequence version replaced NM_022569.2. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.260201.1, SRR1803612.146520.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMN03267773 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000264363.7/ ENSP00000264363.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## |
1 | ATGAATCTTA TTGTGAAACT TCGGAGAAGT TTTCGAACAT TGATTGTTCT CTTAGCTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_072091.1 |
CDS | 424..3042 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAATCTTA TTGTGAAACT TCGGAGAAGT TTTCGAACAT TGATTGTTCT CTTAGCTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu25508 | |
Clone ID Related Accession (Same CDS sequence) | NM_022569.1 , NM_022569.3 , NM_022569.2 | |
Accession Version | NM_022569.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2619bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-24 | |
Organism | Homo sapiens(human) | |
Product | bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AB036429.1, BC012326.1 and AK289670.1. On Dec 9, 2015 this sequence version replaced NM_022569.1. ##Evidence-Data-START## Transcript exon combination :: AB036429.1, SRR1803613.260201.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2157437, SAMN03267773 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAATCTTA TTGTGAAACT TCGGAGAAGT TTTCGAACAT TGATTGTTCT CTTAGCTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_072091.1 |
CDS | 680..3298 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAATCTTA TTGTGAAACT TCGGAGAAGT TTTCGAACAT TGATTGTTCT CTTAGCTACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Characterization of heparan sulfate N-deacetylase/N-sulfotransferase isoform 4 using synthetic oligosaccharide substrates. |
Genome-wide association studies of maximum number of drinks. |
A genome-wide association study (GWAS) for bronchopulmonary dysplasia. |
NDST4 is a novel candidate tumor suppressor gene at chromosome 4q26 and its genetic loss predicts adverse prognosis in colorectal cancer. |
Genome-wide association analysis identifies TYW3/CRYZ and NDST4 loci associated with circulating resistin levels. |