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UBP1 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol UBP1
Entrez Gene ID 7342
Full Name upstream binding protein 1
Synonyms LBP-1B,LBP-1a,LBP1A,LBP1B
General protein information
Preferred Names

upstream binding protein 1

Names

upstream-binding protein 1
transcription factor LBP-1
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

3

3p22.3
Disorder MIM:

609784


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_014517.4 NP_055332.3 upstream-binding protein 1 isoform LBP-1b
NM_001128160.1 NP_001121632.1 upstream-binding protein 1 isoform LBP-1a
NM_001128161.1 NP_001121633.1 upstream-binding protein 1 isoform LBP-1b
NM_014517.5 NP_055332.3 upstream-binding protein 1 isoform LBP-1b

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) Ubp1 NP_001178748.1
Canis lupus familiaris (dog) UBP1 XP_005634259.1
Danio rerio (zebrafish) ubp1 NP_001108046.1
UBP1 XP_001099731.1
Bos taurus (cattle) UBP1 XP_003587658.1
Mus musculus (house mouse) Ubp1 NP_001076788.1
Pan troglodytes (chimpanzee) UBP1 XP_001168549.2
Homo sapiens (human) UBP1 NP_001121633.1
Gallus gallus (chicken) UBP1 XP_426018.3
Anopheles gambiae (African malaria mosquito) AgaP_AGAP007065 XP_308698.4

Gene Ontology


Bibliography

Related articles in PubMed

Transactivation activity of LBP-1 proteins and their dimerization in living cells.
Katsura A, Kimura K, Hosoi K, Tomokuni Y, Nesori M, Goryo K, Numayama-Tsuruta K, Torii S, Yasumoto K, Gotoh O, Takada M, Fukumura H, Sogawa K
Genes to cells : devoted to molecular & cellular mechanisms14(10)1183-96(2009 Oct)

Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
Koutnikova H, Laakso M, Lu L, Combe R, Paananen J, Kuulasmaa T, Kuusisto J, H?ring HU, Hansen T, Pedersen O, Smith U, Hanefeld M, Williams RW, Auwerx J
PLoS genetics5(8)e1000591(2009 Aug)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from first-trimester human placental tissue and their transcriptional regulation.
Henderson YC, Frederick MJ, Wang MT, Hollier LM, Clayman GL
DNA and cell biology27(2)71-9(2008 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data revealed that dimers composed of LBP-1a and LBP-1c were re-formed probably by a partner-exchange of LBP-1b-containing heterodimers.
Title: Transactivation activity of LBP-1 proteins and their dimerization in living cells.

UBP1 is a critical blood pressure determinant using a combination of mouse and human genetics.
Title: Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.

LBP-1b and LBP-9 both stimulate LBP-32/MGR promoter activity.
Title: LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from first-trimester human placental tissue and their transcriptional regulation.

LBP-1b is an important SF1-independent transcriptional activator stimulating P450scc expression in human placental JEG-3 cells, whereas LBP-9 modulates the action of LBP-1b, exerting both positive and negative effects
Title: LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells.

The following UBP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UBP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu06451 NM_014517.5
Latest version!		 Homo sapiens upstream binding protein 1 (UBP1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu06451 NM_001128161.1
Latest version!		 Homo sapiens upstream binding protein 1 (UBP1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu06798 NM_001128160.1
Latest version!		 Homo sapiens upstream binding protein 1 (UBP1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
View Old Accession Versions >>
OHu06451 NM_014517.4 Homo sapiens upstream binding protein 1 (UBP1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu06451
Clone ID Related Accession (Same CDS sequence) NM_014517.4 , NM_001128161.1 , NM_014517.5
Accession Version NM_014517.4 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1623bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product upstream-binding protein 1 isoform LBP-1b
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC047235.1, AK023274.1, AF198487.1 and AL831847.1. On Jun 7, 2008 this sequence version replaced NM_014517.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (LBP-1b). Variants 1 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: BC047235.1, SRR1803612.115907.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGA TGAGGCTTGA GCCTATAATT 
GAAGATGCAG TTGAACATGA GCAGAAAAAG TCCAGCAAGC GGACTTTGCC AGCAGACTAC 
GGTGATTCTC TGGCAAAGCG AGGCAGTTGT TCTCCGTGGC CCGATGCCCC CACAGCCTAT 
GTGAATAACA GCCCTTCCCC AGCGCCCACT TTCACCTCCC CACAGCAGAG CACTTGCAGT 
GTCCCAGACA GCAATTCTTC TTCCCCAAAT CATCAGGGAG ATGGAGCTTC ACAGACCTCT 
GGTGAACAAA TTCAGCCTTC AGCTACGATC CAGGAAACAC AGCAATGGCT GCTCAAAAAC 
AGATTCTCTT CCTACACAAG ACTGTTCTCT AATTTTTCAG GTGCCGACTT ATTAAAACTG 
ACAAAGGAGG ATTTAGTTCA AATTTGTGGT GCAGCCGATG GAATTCGGCT CTATAATTCA 
CTGAAGTCAA GGTCGGTTAG ACCCCGTTTA ACCATCTATG TCTGCCGGGA GCAGCCAAGC 
AGCACAGTGC TGCAAGGGCA GCAGCAAGCT GCAAGCAGTG CAAGCGAGAA TGGCAGTGGG 
GCACCCTATG TTTATCATGC AATCTACTTG GAAGAAATGA TTGCCTCAGA AGTTGCTCGA 
AAACTTGCGC TGGTGTTTAA TATCCCTCTC CACCAAATTA ATCAGGTTTA CAGACAGGGT 
CCCACCGGTA TTCACATTCT TGTTAGTGAT CAGATGGTTC AGAATTTTCA AGATGAGAGT 
TGTTTTTTAT TCTCCACAGT AAAAGCTGAA AGTAGTGATG GCATCCACAT AATTTTGAAG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_055332.3
CDS531..2153
Translation

Target ORF information:

RefSeq Version NM_014517.4
Organism Homo sapiens(human)
Definition Homo sapiens upstream binding protein 1 (UBP1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_014517.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGA TGAGGCTTGA GCCTATAATT 
GAAGATGCAG TTGAACATGA GCAGAAAAAG TCCAGCAAGC GGACTTTGCC AGCAGACTAC 
GGTGATTCTC TGGCAAAGCG AGGCAGTTGT TCTCCGTGGC CCGATGCCCC CACAGCCTAT 
GTGAATAACA GCCCTTCCCC AGCGCCCACT TTCACCTCCC CACAGCAGAG CACTTGCAGT 
GTCCCAGACA GCAATTCTTC TTCCCCAAAT CATCAGGGAG ATGGAGCTTC ACAGACCTCT 
GGTGAACAAA TTCAGCCTTC AGCTACGATC CAGGAAACAC AGCAATGGCT GCTCAAAAAC 
AGATTCTCTT CCTACACAAG ACTGTTCTCT AATTTTTCAG GTGCCGACTT ATTAAAACTG 
ACAAAGGAGG ATTTAGTTCA AATTTGTGGT GCAGCCGATG GAATTCGGCT CTATAATTCA 
CTGAAGTCAA GGTCGGTTAG ACCCCGTTTA ACCATCTATG TCTGCCGGGA GCAGCCAAGC 
AGCACAGTGC TGCAAGGGCA GCAGCAAGCT GCAAGCAGTG CAAGCGAGAA TGGCAGTGGG 
GCACCCTATG TTTATCATGC AATCTACTTG GAAGAAATGA TTGCCTCAGA AGTTGCTCGA 
AAACTTGCGC TGGTGTTTAA TATCCCTCTC CACCAAATTA ATCAGGTTTA CAGACAGGGT 
CCCACCGGTA TTCACATTCT TGTTAGTGAT CAGATGGTTC AGAATTTTCA AGATGAGAGT 
TGTTTTTTAT TCTCCACAGT AAAAGCTGAA AGTAGTGATG GCATCCACAT AATTTTGAAG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu06451
Clone ID Related Accession (Same CDS sequence) NM_014517.4 , NM_001128161.1 , NM_014517.5
Accession Version NM_001128161.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1623bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-01
Organism Homo sapiens(human)
Product upstream-binding protein 1 isoform LBP-1b
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK293100.1, DB131031.1, BC047235.1 and AL831847.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 encode the same isoform (LBP-1b). ##Evidence-Data-START## Transcript exon combination :: AK293100.1, SRR1803616.86184.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGA TGAGGCTTGA GCCTATAATT 
GAAGATGCAG TTGAACATGA GCAGAAAAAG TCCAGCAAGC GGACTTTGCC AGCAGACTAC 
GGTGATTCTC TGGCAAAGCG AGGCAGTTGT TCTCCGTGGC CCGATGCCCC CACAGCCTAT 
GTGAATAACA GCCCTTCCCC AGCGCCCACT TTCACCTCCC CACAGCAGAG CACTTGCAGT 
GTCCCAGACA GCAATTCTTC TTCCCCAAAT CATCAGGGAG ATGGAGCTTC ACAGACCTCT 
GGTGAACAAA TTCAGCCTTC AGCTACGATC CAGGAAACAC AGCAATGGCT GCTCAAAAAC 
AGATTCTCTT CCTACACAAG ACTGTTCTCT AATTTTTCAG GTGCCGACTT ATTAAAACTG 
ACAAAGGAGG ATTTAGTTCA AATTTGTGGT GCAGCCGATG GAATTCGGCT CTATAATTCA 
CTGAAGTCAA GGTCGGTTAG ACCCCGTTTA ACCATCTATG TCTGCCGGGA GCAGCCAAGC 
AGCACAGTGC TGCAAGGGCA GCAGCAAGCT GCAAGCAGTG CAAGCGAGAA TGGCAGTGGG 
GCACCCTATG TTTATCATGC AATCTACTTG GAAGAAATGA TTGCCTCAGA AGTTGCTCGA 
AAACTTGCGC TGGTGTTTAA TATCCCTCTC CACCAAATTA ATCAGGTTTA CAGACAGGGT 
CCCACCGGTA TTCACATTCT TGTTAGTGAT CAGATGGTTC AGAATTTTCA AGATGAGAGT 
TGTTTTTTAT TCTCCACAGT AAAAGCTGAA AGTAGTGATG GCATCCACAT AATTTTGAAG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121633.1
CDS150..1772
Translation

Target ORF information:

RefSeq Version NM_001128161.1
Organism Homo sapiens(human)
Definition Homo sapiens upstream binding protein 1 (UBP1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001128161.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGA TGAGGCTTGA GCCTATAATT 
GAAGATGCAG TTGAACATGA GCAGAAAAAG TCCAGCAAGC GGACTTTGCC AGCAGACTAC 
GGTGATTCTC TGGCAAAGCG AGGCAGTTGT TCTCCGTGGC CCGATGCCCC CACAGCCTAT 
GTGAATAACA GCCCTTCCCC AGCGCCCACT TTCACCTCCC CACAGCAGAG CACTTGCAGT 
GTCCCAGACA GCAATTCTTC TTCCCCAAAT CATCAGGGAG ATGGAGCTTC ACAGACCTCT 
GGTGAACAAA TTCAGCCTTC AGCTACGATC CAGGAAACAC AGCAATGGCT GCTCAAAAAC 
AGATTCTCTT CCTACACAAG ACTGTTCTCT AATTTTTCAG GTGCCGACTT ATTAAAACTG 
ACAAAGGAGG ATTTAGTTCA AATTTGTGGT GCAGCCGATG GAATTCGGCT CTATAATTCA 
CTGAAGTCAA GGTCGGTTAG ACCCCGTTTA ACCATCTATG TCTGCCGGGA GCAGCCAAGC 
AGCACAGTGC TGCAAGGGCA GCAGCAAGCT GCAAGCAGTG CAAGCGAGAA TGGCAGTGGG 
GCACCCTATG TTTATCATGC AATCTACTTG GAAGAAATGA TTGCCTCAGA AGTTGCTCGA 
AAACTTGCGC TGGTGTTTAA TATCCCTCTC CACCAAATTA ATCAGGTTTA CAGACAGGGT 
CCCACCGGTA TTCACATTCT TGTTAGTGAT CAGATGGTTC AGAATTTTCA AGATGAGAGT 
TGTTTTTTAT TCTCCACAGT AAAAGCTGAA AGTAGTGATG GCATCCACAT AATTTTGAAG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu06451
Clone ID Related Accession (Same CDS sequence) NM_014517.4 , NM_001128161.1 , NM_014517.5
Accession Version NM_014517.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1623bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-02
Organism Homo sapiens(human)
Product upstream-binding protein 1 isoform LBP-1b
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC093114.2, BC047235.1, AK023274.1, AF198487.1 and AL831847.1. On Nov 23, 2018 this sequence version replaced NM_014517.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (LBP-1b). Variants 1 and 3 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: BC047235.1, SRR1803612.115907.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000283629.8/ ENSP00000283629.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGA TGAGGCTTGA GCCTATAATT 
GAAGATGCAG TTGAACATGA GCAGAAAAAG TCCAGCAAGC GGACTTTGCC AGCAGACTAC 
GGTGATTCTC TGGCAAAGCG AGGCAGTTGT TCTCCGTGGC CCGATGCCCC CACAGCCTAT 
GTGAATAACA GCCCTTCCCC AGCGCCCACT TTCACCTCCC CACAGCAGAG CACTTGCAGT 
GTCCCAGACA GCAATTCTTC TTCCCCAAAT CATCAGGGAG ATGGAGCTTC ACAGACCTCT 
GGTGAACAAA TTCAGCCTTC AGCTACGATC CAGGAAACAC AGCAATGGCT GCTCAAAAAC 
AGATTCTCTT CCTACACAAG ACTGTTCTCT AATTTTTCAG GTGCCGACTT ATTAAAACTG 
ACAAAGGAGG ATTTAGTTCA AATTTGTGGT GCAGCCGATG GAATTCGGCT CTATAATTCA 
CTGAAGTCAA GGTCGGTTAG ACCCCGTTTA ACCATCTATG TCTGCCGGGA GCAGCCAAGC 
AGCACAGTGC TGCAAGGGCA GCAGCAAGCT GCAAGCAGTG CAAGCGAGAA TGGCAGTGGG 
GCACCCTATG TTTATCATGC AATCTACTTG GAAGAAATGA TTGCCTCAGA AGTTGCTCGA 
AAACTTGCGC TGGTGTTTAA TATCCCTCTC CACCAAATTA ATCAGGTTTA CAGACAGGGT 
CCCACCGGTA TTCACATTCT TGTTAGTGAT CAGATGGTTC AGAATTTTCA AGATGAGAGT 
TGTTTTTTAT TCTCCACAGT AAAAGCTGAA AGTAGTGATG GCATCCACAT AATTTTGAAG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_055332.3
CDS558..2180
Translation

Target ORF information:

RefSeq Version NM_014517.5
Organism Homo sapiens(human)
Definition Homo sapiens upstream binding protein 1 (UBP1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_014517.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGA TGAGGCTTGA GCCTATAATT 
GAAGATGCAG TTGAACATGA GCAGAAAAAG TCCAGCAAGC GGACTTTGCC AGCAGACTAC 
GGTGATTCTC TGGCAAAGCG AGGCAGTTGT TCTCCGTGGC CCGATGCCCC CACAGCCTAT 
GTGAATAACA GCCCTTCCCC AGCGCCCACT TTCACCTCCC CACAGCAGAG CACTTGCAGT 
GTCCCAGACA GCAATTCTTC TTCCCCAAAT CATCAGGGAG ATGGAGCTTC ACAGACCTCT 
GGTGAACAAA TTCAGCCTTC AGCTACGATC CAGGAAACAC AGCAATGGCT GCTCAAAAAC 
AGATTCTCTT CCTACACAAG ACTGTTCTCT AATTTTTCAG GTGCCGACTT ATTAAAACTG 
ACAAAGGAGG ATTTAGTTCA AATTTGTGGT GCAGCCGATG GAATTCGGCT CTATAATTCA 
CTGAAGTCAA GGTCGGTTAG ACCCCGTTTA ACCATCTATG TCTGCCGGGA GCAGCCAAGC 
AGCACAGTGC TGCAAGGGCA GCAGCAAGCT GCAAGCAGTG CAAGCGAGAA TGGCAGTGGG 
GCACCCTATG TTTATCATGC AATCTACTTG GAAGAAATGA TTGCCTCAGA AGTTGCTCGA 
AAACTTGCGC TGGTGTTTAA TATCCCTCTC CACCAAATTA ATCAGGTTTA CAGACAGGGT 
CCCACCGGTA TTCACATTCT TGTTAGTGAT CAGATGGTTC AGAATTTTCA AGATGAGAGT 
TGTTTTTTAT TCTCCACAGT AAAAGCTGAA AGTAGTGATG GCATCCACAT AATTTTGAAG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu06798
Clone ID Related Accession (Same CDS sequence) NM_001128160.1
Accession Version NM_001128160.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1515bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-01
Organism Homo sapiens(human)
Product upstream-binding protein 1 isoform LBP-1a
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC047235.1, AK023274.1 and AL831847.1. Transcript Variant: This variant (2) lacks an in-frame exon in the mid-coding region compared to variant 1. The resulting isoform (LBP-1a) is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: AK023274.1, SRR1660809.229268.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGT GTTCTCCGTG GCCCGATGCC 
CCCACAGCCT ATGTGAATAA CAGCCCTTCC CCAGCGCCCA CTTTCACCTC CCCACAGCAG 
AGCACTTGCA GTGTCCCAGA CAGCAATTCT TCTTCCCCAA ATCATCAGGG AGATGGAGCT 
TCACAGACCT CTGGTGAACA AATTCAGCCT TCAGCTACGA TCCAGGAAAC ACAGCAATGG 
CTGCTCAAAA ACAGATTCTC TTCCTACACA AGACTGTTCT CTAATTTTTC AGGTGCCGAC 
TTATTAAAAC TGACAAAGGA GGATTTAGTT CAAATTTGTG GTGCAGCCGA TGGAATTCGG 
CTCTATAATT CACTGAAGTC AAGGTCGGTT AGACCCCGTT TAACCATCTA TGTCTGCCGG 
GAGCAGCCAA GCAGCACAGT GCTGCAAGGG CAGCAGCAAG CTGCAAGCAG TGCAAGCGAG 
AATGGCAGTG GGGCACCCTA TGTTTATCAT GCAATCTACT TGGAAGAAAT GATTGCCTCA 
GAAGTTGCTC GAAAACTTGC GCTGGTGTTT AATATCCCTC TCCACCAAAT TAATCAGGTT 
TACAGACAGG GTCCCACCGG TATTCACATT CTTGTTAGTG ATCAGATGGT TCAGAATTTT 
CAAGATGAGA GTTGTTTTTT ATTCTCCACA GTAAAAGCTG AAAGTAGTGA TGGCATCCAC 
ATAATTTTGA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001121632.1
CDS531..2045
Translation

Target ORF information:

RefSeq Version NM_001128160.1
Organism Homo sapiens(human)
Definition Homo sapiens upstream binding protein 1 (UBP1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001128160.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGCCTGGG TGCTCAAGAT GGACGAGGTG ATCGAGTCCG GGCTGGTGCA CGACTTCGAC 
GCCAGCCTCT CGGGCATCGG GCAGGAACTG GGCGCCGGCG CTTACAGCAT GAGTGATGTC 
TTGGCATTGC CCATTTTCAA GCAGGAAGAT TCCAGCCTTC CATTGGATGG TGAAACAGAG 
CACCCACCCT TTCAGTATGT GATGTGTGCT GCAACGTCAC CAGCAGTAAA ACTGCATGAT 
GAAACGCTTA CTTATTTGAA CCAAGGTCAG TCATATGAAA TTCGGATGCT GGATAATCGG 
AAAATGGGTG ATATGCCTGA GATCAATGGA AAATTAGTAA AGAGCATCAT AAGGGTTGTA 
TTCCATGACA GACGGCTACA ATACACAGAG CATCAGCAAC TTGAAGGATG GAAGTGGAAT 
CGCCCAGGAG ACAGACTTCT TGATTTAGAT ATTCCAATGT CTGTGGGAAT AATTGACACA 
AGGACGAATC CAAGCCAGTT AAATGCGGTT GAATTTCTGT GGGACCCAGC AAAACGCACC 
TCTGCTTTCA TTCAGGTACA CTGCATCAGC ACAGAATTTA CTCCACGGAA GCACGGAGGT 
GAAAAGGGAG TGCCCTTTAG GATCCAGGTT GACACCTTTA AGCAGAATGA AAATGGAGAA 
TACACAGATC ATCTACACTC AGCTAGCTGC CAAATCAAAG TTTTTAAGCC TAAAGGTGCA 
GACAGGAAAC AAAAAACTGA CCGAGAGAAG ATGGAGAAGA GAACAGCTCA TGAAAAAGAA 
AAGTATCAGC CGTCCTATGA TACCACAATC CTCACAGAGT GTTCTCCGTG GCCCGATGCC 
CCCACAGCCT ATGTGAATAA CAGCCCTTCC CCAGCGCCCA CTTTCACCTC CCCACAGCAG 
AGCACTTGCA GTGTCCCAGA CAGCAATTCT TCTTCCCCAA ATCATCAGGG AGATGGAGCT 
TCACAGACCT CTGGTGAACA AATTCAGCCT TCAGCTACGA TCCAGGAAAC ACAGCAATGG 
CTGCTCAAAA ACAGATTCTC TTCCTACACA AGACTGTTCT CTAATTTTTC AGGTGCCGAC 
TTATTAAAAC TGACAAAGGA GGATTTAGTT CAAATTTGTG GTGCAGCCGA TGGAATTCGG 
CTCTATAATT CACTGAAGTC AAGGTCGGTT AGACCCCGTT TAACCATCTA TGTCTGCCGG 
GAGCAGCCAA GCAGCACAGT GCTGCAAGGG CAGCAGCAAG CTGCAAGCAG TGCAAGCGAG 
AATGGCAGTG GGGCACCCTA TGTTTATCAT GCAATCTACT TGGAAGAAAT GATTGCCTCA 
GAAGTTGCTC GAAAACTTGC GCTGGTGTTT AATATCCCTC TCCACCAAAT TAATCAGGTT 
TACAGACAGG GTCCCACCGG TATTCACATT CTTGTTAGTG ATCAGATGGT TCAGAATTTT 
CAAGATGAGA GTTGTTTTTT ATTCTCCACA GTAAAAGCTG AAAGTAGTGA TGGCATCCAC 
ATAATTTTGA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Transactivation activity of LBP-1 proteins and their dimerization in living cells.
Genes to cells : devoted to molecular & cellular mechanisms14(10)1183-96(2009 Oct)
Katsura A,Kimura K,Hosoi K,Tomokuni Y,Nesori M,Goryo K,Numayama-Tsuruta K,Torii S,Yasumoto K,Gotoh O,Takada M,Fukumura H,Sogawa K


book

Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics.
PLoS genetics5(8)e1000591(2009 Aug)
Koutnikova H,Laakso M,Lu L,Combe R,Paananen J,Kuulasmaa T,Kuusisto J,H?ring HU,Hansen T,Pedersen O,Smith U,Hanefeld M,Williams RW,Auwerx J


book

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM


book

LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from first-trimester human placental tissue and their transcriptional regulation.
DNA and cell biology27(2)71-9(2008 Feb)
Henderson YC,Frederick MJ,Wang MT,Hollier LM,Clayman GL