Gene Symbol | CRELD2 |
Entrez Gene ID | 79174 |
Full Name | cysteine rich with EGF like domains 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » CRELD2 cDNA ORF clone
Gene Symbol | CRELD2 |
Entrez Gene ID | 79174 |
Full Name | cysteine rich with EGF like domains 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_024324.4 | NP_077300.3 | cysteine-rich with EGF-like domain protein 2 isoform b precursor |
NM_001135101.3 | NP_001128573.1 | protein disulfide isomerase CRELD2 isoform a precursor |
XM_011530372.2 | XP_011528674.1 | cysteine-rich with EGF-like domain protein 2 isoform X4 |
NM_001135101.2 | NP_001128573.1 | cysteine-rich with EGF-like domain protein 2 isoform a precursor |
NM_001284317.2 | NP_001271246.1 | protein disulfide isomerase CRELD2 isoform c precursor |
XM_005261737.3 | XP_005261794.1 | protein disulfide isomerase CRELD2 isoform X1 |
XM_017028938.1 | XP_016884427.1 | protein disulfide isomerase CRELD2 isoform X3 |
NM_024324.5 | NP_077300.3 | protein disulfide isomerase CRELD2 isoform b precursor |
NM_001284318.1 | NP_001271247.1 | cysteine-rich with EGF-like domain protein 2 isoform d precursor |
XM_005261738.4 | XP_005261795.1 | cysteine-rich with EGF-like domain protein 2 isoform X2 |
NM_001284318.2 | NP_001271247.1 | protein disulfide isomerase CRELD2 isoform d precursor |
XM_005261737.2 | XP_005261794.1 | cysteine-rich with EGF-like domain protein 2 isoform X1 |
NM_001284317.1 | NP_001271246.1 | cysteine-rich with EGF-like domain protein 2 isoform c precursor |
XM_005261738.5 | XP_005261795.1 | protein disulfide isomerase CRELD2 isoform X2 |
XM_011530372.3 | XP_011528674.1 | protein disulfide isomerase CRELD2 isoform X4 |
LOC720586 | XP_001116152.2 | |
Canis lupus familiaris (dog) | CRELD2 | XP_005625788.1 |
Bos taurus (cattle) | CRELD2 | NP_001039656.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100497878 | XP_002932231.1 |
Homo sapiens (human) | CRELD2 | NP_001128573.1 |
Pan troglodytes (chimpanzee) | CRELD2 | XP_001139663.1 |
Danio rerio (zebrafish) | creld2 | NP_956817.1 |
Caenorhabditis elegans (roundworm) | F09E8.2 | NP_502530.1 |
Rattus norvegicus (Norway rat) | Creld2 | NP_001032285.1 |
Gallus gallus (chicken) | CRELD2 | NP_001186426.1 |
Drosophila melanogaster (fruit fly) | CG11377 | NP_608490.1 |
Mus musculus (house mouse) | Creld2 | NP_083996.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007968 | XP_317502.3 |
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.
Navarini AA, Simpson MA, Weale M, Knight J, Carlavan I, Reiniche P, Burden DA, Layton A, Bataille V, Allen M, Pleass R, Pink A, Creamer D, English J, Munn S, Walton S, , Willis C, D?ret S, Voegel JJ, Spector T, Smith CH, Trembath RC, Barker JN
Nature communications54020(2014 Jun)
Characterization of V-ATPase inhibitor-induced secretion of cysteine-rich with EGF-like domains 2.
Oh-hashi K, Kanamori Y, Hirata Y, Kiuchi K
Cell biology and toxicology30(3)127-36(2014 Jun)
Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases.
Hartley CL, Edwards S, Mullan L, Bell PA, Fresquet M, Boot-Handford RP, Briggs MD
Human molecular genetics22(25)5262-75(2013 Dec)
Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells.
Zhang J, Weng Y, Liu X, Wang J, Zhang W, Kim SH, Zhang H, Li R, Kong Y, Chen X, Shui W, Wang N, Zhao C, Wu N, He Y, Nan G, Chen X, Wen S, Zhang H, Deng F, Wan L, Luu HH, Haydon RC, Shi LL, He TC, Shi Q
PloS one8(9)e73086(2013)
Toward an understanding of the protein interaction network of the human liver.
Wang J, Huo K, Ma L, Tang L, Li D, Huang X, Yuan Y, Li C, Wang W, Guan W, Chen H, Jin C, Wei J, Zhang W, Yang Y, Liu Q, Zhou Y, Zhang C, Wu Z, Xu W, Zhang Y, Liu T, Yu D, Zhang Y, Chen L, Zhu D, Zhong X, Kang L, Gan X, Yu X, Ma Q, Yan J, Zhou L, Liu Z, Zhu Y, Zhou T, He F, Yang X
Molecular systems biology7536(2011 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
intravesicular acidification by V-ATPase regulates the secretion of CRELD2 without relying on the balance of intracellular calcium ions and the expression of endoplasmic reticulum chaperones such as GRP78 and protein disulfide isomerase.
Title: Characterization of V-ATPase inhibitor-induced secretion of cysteine-rich with EGF-like domains 2.
We demonstrate that Armet and Creld2 are genotype-specific ER stress response proteins with substrate specificities, and that aggregation of mutant matrilin-3 is a key disease trigger in MED that could be exploited as a potential therapeutic target
Title: Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases.
results strongly suggest that Creld2 may be directly regulated by BMP9 and ER stress response may play an important role in regulating osteogenic differentiation
Title: Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells.
Mapping of CRELD2 by FISH shows that it maps to 22q13 rather than the GenBank reported locus of 22p13.
Title: CRELD2: gene mapping, alternate splicing, and comparative genomic identification of the promoter region.
CRELD2 can act as a specific regulator of alpha4beta2 nAChR expression
Title: The cysteine-rich with EGF-like domains 2 (CRELD2) protein interacts with the large cytoplasmic domain of human neuronal nicotinic acetylcholine receptor alpha4 and beta2 subunits.
The following CRELD2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CRELD2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu27576 | |
Clone ID Related Accession (Same CDS sequence) | NM_001284318.1 , NM_001284318.2 | |
Accession Version | NM_001284318.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | cysteine-rich with EGF-like domain protein 2 isoform d precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1, BC002894.1 and BQ003113.1. On Sep 27, 2013 this sequence version replaced XM_005261740.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in both the central and 3' coding regions, compared to variant 1, resulting in an isoform (d, also known as CRELD2-alpha) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: BC002894.1, DQ470676.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001271247.1 |
CDS | 141..1106 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001284318.1 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu27576 | |
Clone ID Related Accession (Same CDS sequence) | NM_001284318.1 , NM_001284318.2 | |
Accession Version | NM_001284318.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-28 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform d precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1, BC002894.1 and BQ003113.1. On Jun 2, 2019 this sequence version replaced NM_001284318.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in both the central and 3' coding regions, compared to variant 1, resulting in an isoform (d, also known as CRELD2-alpha) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: DQ470676.1, BC002894.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2144335, SAMEA2145240 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001271247.1 |
CDS | 137..1102 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001284318.2 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00475 | |
Clone ID Related Accession (Same CDS sequence) | NM_001135101.3 , NM_001135101.2 | |
Accession Version | NM_001135101.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-28 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform a precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1 and DQ470679.1. On Jun 2, 2019 this sequence version replaced NM_001135101.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as CRELD2-epsilon). ##Evidence-Data-START## Transcript exon combination :: DQ470679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001128573.1 |
CDS | 137..1345 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001135101.3 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00475 | |
Clone ID Related Accession (Same CDS sequence) | NM_001135101.3 , NM_001135101.2 | |
Accession Version | NM_001135101.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | cysteine-rich with EGF-like domain protein 2 isoform a precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1, DQ470679.1 and BQ003113.1. On Sep 27, 2013 this sequence version replaced NM_001135101.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a, also known as CRELD2-epsilon). ##Evidence-Data-START## Transcript exon combination :: DQ470679.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001128573.1 |
CDS | 141..1349 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001135101.2 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00580 | |
Clone ID Related Accession (Same CDS sequence) | NM_024324.4 , NM_024324.5 | |
Accession Version | NM_024324.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-23 | |
Organism | Homo sapiens(human) | |
Product | cysteine-rich with EGF-like domain protein 2 isoform b precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1, AY358355.1 and BQ003113.1. On Sep 27, 2013 this sequence version replaced NM_024324.3. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (b, also known as CRELD2-delta) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.375127.1, SRR1163655.346412.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_077300.3 |
CDS | 141..1202 |
Translation |
Target ORF information:
Target ORF information:
|
NM_024324.4 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00580 | |
Clone ID Related Accession (Same CDS sequence) | NM_024324.4 , NM_024324.5 | |
Accession Version | NM_024324.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1062bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-03 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform b precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1 and AY358355.1. On Jun 2, 2019 this sequence version replaced NM_024324.4. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (b, also known as CRELD2-delta) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: AY358355.1, SRR1163655.113924.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_077300.3 |
CDS | 137..1198 |
Translation |
Target ORF information:
Target ORF information:
|
NM_024324.5 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05330 | |
Clone ID Related Accession (Same CDS sequence) | NM_001284317.2 , NM_001284317.1 | |
Accession Version | NM_001284317.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-28 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform c precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1, DQ470677.1 and BQ003113.1. On Jun 2, 2019 this sequence version replaced NM_001284317.1. Transcript Variant: This variant (3) lacks two alternate in-frame exons in the central coding region, compared to variant 1, resulting in an isoform (c, also known as CRELD2-gamma) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: DQ470677.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001271246.1 |
CDS | 137..1114 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001284317.2 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05330 | |
Clone ID Related Accession (Same CDS sequence) | NM_001284317.2 , NM_001284317.1 | |
Accession Version | NM_001284317.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 978bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | cysteine-rich with EGF-like domain protein 2 isoform c precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BI462292.1, DQ470677.1 and BQ003113.1. On Sep 27, 2013 this sequence version replaced XM_005261739.1. Transcript Variant: This variant (3) lacks two alternate in-frame exons in the central coding region, compared to variant 1, resulting in an isoform (c, also known as CRELD2-gamma) that is shorter than isoform a. ##Evidence-Data-START## Transcript exon combination :: DQ470677.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001271246.1 |
CDS | 141..1118 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001284317.1 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53684 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261737.3 , XM_005261737.2 | |
Accession Version | XM_005261737.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005261737.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261794.1 |
CDS | 118..1329 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005261737.3 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53684 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261737.3 , XM_005261737.2 | |
Accession Version | XM_005261737.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | cysteine-rich with EGF-like domain protein 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005261737.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261794.1 |
CDS | 129..1340 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005261737.2 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53685 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261738.4 , XM_005261738.5 | |
Accession Version | XM_005261738.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | cysteine-rich with EGF-like domain protein 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005261738.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261795.1 |
CDS | 135..1256 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005261738.4 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53685 | |
Clone ID Related Accession (Same CDS sequence) | XM_005261738.4 , XM_005261738.5 | |
Accession Version | XM_005261738.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005261738.4. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005261795.1 |
CDS | 118..1239 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005261738.5 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu71820 | |
Clone ID Related Accession (Same CDS sequence) | XM_011530372.2 , XM_011530372.3 | |
Accession Version | XM_011530372.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | cysteine-rich with EGF-like domain protein 2 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011530372.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011528674.1 |
CDS | 129..755 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011530372.2 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu71820 | |
Clone ID Related Accession (Same CDS sequence) | XM_011530372.2 , XM_011530372.3 | |
Accession Version | XM_011530372.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 627bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011530372.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011528674.1 |
CDS | 118..744 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011530372.3 |
1 | ATGCGCCTGC CGCGCCGGGC CGCGCTGGGG CTCCTGCCGC TTCTGCTGCT GCTGCCGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu93580 | |
Clone ID Related Accession (Same CDS sequence) | XM_017028938.1 | |
Accession Version | XM_017028938.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 759bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | protein disulfide isomerase CRELD2 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000022.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTTTCCT CCATCCTCAG GAAGAGCGAA TATCCTGACT TATTCGAGTG GTTTTGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016884427.1 |
CDS | 368..1126 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017028938.1 |
1 | ATGTTTTCCT CCATCCTCAG GAAGAGCGAA TATCCTGACT TATTCGAGTG GTTTTGTGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. |
Characterization of V-ATPase inhibitor-induced secretion of cysteine-rich with EGF-like domains 2. |
Armet/Manf and Creld2 are components of a specialized ER stress response provoked by inappropriate formation of disulphide bonds: implications for genetic skeletal diseases. |
Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. |
Toward an understanding of the protein interaction network of the human liver. |