RABEP2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RABEP2
Entrez Gene ID	79874
Full Name	rabaptin, RAB GTPase binding effector protein 2
Synonyms	FRA
General protein information	Preferred Names rabaptin, RAB GTPase binding effector protein 2 Names rab GTPase-binding effector protein 2 Rabaptin-5 beta rabaptin-5beta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Disorder MIM:	611869

mRNA and Protein(s)

mRNA	Protein	Name
NM_024816.2	NP_079092.2	rab GTPase-binding effector protein 2
NM_024816.3	NP_079092.2	rab GTPase-binding effector protein 2

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RABEP2	NP_001076877.2
Mus musculus (house mouse)	Rabep2	NP_085043.2
Rattus norvegicus (Norway rat)	Rabep2	NP_085074.1
Homo sapiens (human)	RABEP2	NP_079092.2
Pan troglodytes (chimpanzee)	RABEP2	XP_003952863.1
Canis lupus familiaris (dog)	RABEP2	XP_547072.3

Gene Ontology
Bibliography

Related articles in PubMed

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3).
Logie L, Van Aalten L, Knebel A, Force T, Hastie CJ, MacLauchlan H, Campbell DG, Gourlay R, Prescott A, Davidson J, Fuller W, Sutherland C
Scientific reports7(1)17682(2017 Dec)

SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling.
Airik R, Schueler M, Airik M, Cho J, Ulanowicz KA, Porath JD, Hurd TW, Bekker-Jensen S, Schr?der JM, Andersen JS, Hildebrandt F
PloS one11(5)e0156081(2016)

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Berndt SI, Gustafsson S, M?gi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson ?, Johnson T, Kanoni S, Kleber ME, K?nig IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, M?ller-Nurasyid M, Ngwa JS, Nolte IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J, Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW, Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL, Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS, Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S, Estrada K, Evans DM, Farrall M, Ferrario MM, Ferri?res J, Franke L, Frau F, Gejman PV, Grallert H, Gr?nberg H, Gudnason V, Hall AS, Hall P, Hartikainen AL, Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE, Hypp?nen E, Iribarren C, Jacobs KB, Jansson JO, Jula A, K?h?nen M, Kathiresan S, Kee F, Khaw KT, Kivim?ki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindstr?m J, Liu J, Liuzzi A, Lokki ML, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D, M?rz W, Mateo Leach I, McKnight B, Medland SE, Mihailov E, Milani L, Montgomery GW, Mooser V, M?hleisen TW, Munroe PB, Musk AW, Narisu N, Navis G, Nicholson G, Nohr EA, Ong KK, Oostra BA, Palmer CN, Palotie A, Peden JF, Pedersen N, Peters A, Polasek O, Pouta A, Pramstaller PP, Prokopenko I, P?tter C, Radhakrishnan A, Raitakari O, Rendon A, Rivadeneira F, Rudan I, Saaristo TE, Sambrook JG, Sanders AR, Sanna S, Saramies J, Schipf S, Schreiber S, Schunkert H, Shin SY, Signorini S, Sinisalo J, Skrobek B, Soranzo N, Stan??kov? A, Stark K, Stephens JC, Stirrups K, Stolk RP, Stumvoll M, Swift AJ, Theodoraki EV, Thorand B, Tregouet DA, Tremoli E, Van der Klauw MM, van Meurs JB, Vermeulen SH, Viikari J, Virtamo J, Vitart V, Waeber G, Wang Z, Wid?n E, Wild SH, Willemsen G, Winkelmann BR, Witteman JC, Wolffenbuttel BH, Wong A, Wright AF, Zillikens MC, Amouyel P, Boehm BO, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Cupples LA, Cusi D, Dedoussis GV, Erdmann J, Eriksson JG, Franks PW, Froguel P, Gieger C, Gyllensten U, Hamsten A, Harris TB, Hengstenberg C, Hicks AA, Hingorani A, Hinney A, Hofman A, Hovingh KG, Hveem K, Illig T, Jarvelin MR, J?ckel KH, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kuh D, Laakso M, Lehtim?ki T, Levinson DF, Martin NG, Metspalu A, Morris AD, Nieminen MS, Nj?lstad I, Ohlsson C, Oldehinkel AJ, Ouwehand WH, Palmer LJ, Penninx B, Power C, Province MA, Psaty BM, Qi L, Rauramaa R, Ridker PM, Ripatti S, Salomaa V, Samani NJ, Snieder H, S?rensen TI, Spector TD, Stefansson K, T?njes A, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Vollenweider P, Wallaschofski H, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Abecasis GR, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunian T, Heid IM, Hunter D, Kaplan RC, Karpe F, Moffatt MF, Mohlke KL, O'Connell JR, Pawitan Y, Schadt EE, Schlessinger D, Steinthorsdottir V, Strachan DP, Thorsteinsdottir U, van Duijn CM, Visscher PM, Di Blasio AM, Hirschhorn JN, Lindgren CM, Morris AP, Meyre D, Scherag A, McCarthy MI, Speliotes EK, North KE, Loos RJ, Ingelsson E
Nature genetics45(5)501-12(2013 May)

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, B?ning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, , Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH
Nature491(7422)119-24(2012 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Pyk2 regulation is associated with increased expression of Fra-1 and JunD, activator protein-1 transcription factors known to be required for involucrin expression.
Title: The role of proline-rich protein tyrosine kinase 2 in differentiation-dependent signaling in human epidermal keratinocytes.

FRA-1 expression, including its intracellular localization, may be considered a useful marker for hyperplastic and neoplastic proliferative breast disorders
Title: FRA-1 protein overexpression is a feature of hyperplastic and neoplastic breast disorders.

The following RABEP2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RABEP2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu17297	NM_024816.3 Latest version!	Homo sapiens rabaptin, RAB GTPase binding effector protein 2 (RABEP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
View Old Accession Versions >>
OHu17297	NM_024816.2	Homo sapiens rabaptin, RAB GTPase binding effector protein 2 (RABEP2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RABEP2 ( NM_024816.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_079092.2 Homo sapiens rabaptin, RAB GTPase binding effector protein 2 (RABEP2), mRNA.

Price & Availability↑

CloneID	OHu17297
Clone ID Related Accession (Same CDS sequence)	NM_024816.2 , NM_024816.3
Accession Version	NM_024816.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	rab GTPase-binding effector protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK026935.1 and BC046118.1. On Nov 15, 2006 this sequence version replaced NM_024816.1. ##Evidence-Data-START## Transcript exon combination :: AK026935.1, AK092299.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGCGGCAG CTGCGCCGGT GGCCGCGGAC GACGATGAGC GGCGGCGGCG GCCGGGGGCT 
GCACTGGAGG ACTCCCGGTC CCAGGAAGGG GCAAATGGTG AGGCCGAGTC AGGTGAGCTC 
AGCCGGCTTC GGGCTGAGCT GGCAGGCGCC CTGGCAGAAA TGGAAACCAT GAAGGCTGTG 
GCAGAGGTGA GCGAGAGCAC GAAGGCCGAG GCTGTGGCTG CGGTGCAGCG GCAGTGCCAA 
GAGGAGGTGG CCTCGCTGCA GGCCATCCTG AAAGACTCCA TCAGCAGCTA TGAAGCCCAG 
ATCACCGCCC TGAAGCAGGA GCGACAGCAG CAGCAGCAGG ACTGTGAGGA GAAGGAGCGG 
GAGCTGGGCC GCCTGAAGCA GCTGCTGTCC CGGGCCTACC CCCTGGACTC CCTGGAGAAG 
CAGATGGAAA AGGCCCACGA GGACTCGGAG AAGCTGCGGG AGATCGTACT GCCCATGGAA 
AAGGAGATCG AGGAGCTGAA GGCGAAGCTG CTGAGGGCCG AGGAGCTGAT TCAGGAGATC 
CAGAGACGTC CCCGGCATGC CCCTTCCCTG CACGGCTCCA CGGAGTTGCT GCCCCTGTCC 
CGGGATCCAT CGCCCCCGCT GGAGCCTCTG GAGGAGCTGA GCGGAGATGG GGGTCCAGCC 
GCTGAGGCCT TCGCTCACAA CTGCGATGAC AGCGCCTCCA TCTCCTCCTT CTCCCTTGGC 
GGTGGGGTCG GCAGCAGCTC CTCCCTGCCC CAAAGCCGCC AGGGCCTGAG CCCTGAACAG 
GAAGAGACGG CCTCGCTGGT GTCTACGGGC ACCCTGGTTC CCGAGGGCAT CTACCTGCCC 
CCTCCTGGCT ACCAGCTCGT CCCAGACACT CAGTGGGAGC AGCTGCAGAC AGAGGGCCGA 
CAGCTGCAGA AGGACCTGGA GAGCGTCAGT CGCGAGCGGG ACGAGCTCCA AGAGGGCCTG 
AGACGGAGCA ATGAGGACTG TGCCAAGCAG ATGCAGGTGC TCCTGGCCCA GGTCCAGAAC 
TCAGAGCAGC TGCTGCGGAC CCTGCAAGGG ACCGTGAGCC AGGCCCAGGA GCGGGTGCAG 
CTGCAGATGG CGGAGCTGGT CACCACCCAC AAGTGCCTGC ACCATGAGGT AAAGCGGTTG 
AATGAGGAAA ACCAAGGGCT CCGGGCCGAG CAGCTGCCAT CCTCAGCCCC CCAGGGCTCG 
CAGCAGGAGC AGGGCGAGGA GGAATCACTG CCCAGCTCTG TGCCAGAGCT GCAGCAGCTG 
CTGTGCTGCA CGCGGCAAGA GGCGAGGGCC CGGCTGCAGG CCCAGGAGCA CGGGGCCGAG 
CGCCTGCGGA TCGAGATCGT GACGCTGCGG GAGGCTCTGG AGGAGGAGAC AGTGGCCAGG 
GCCAGCCTGG AGGGGCAGCT GAGGGTGCAG CGGGAGGAGA CAGAGGTGCT GGAGGCCTCC 
CTGTGCAGCC TGAGGACAGA GATGGAGCGG GTGCAGCAGG AACAGAGCAA GGCCCAGCTC 
CCAGACCTCC TCTCAGAACA GAGGGCCAAG GTGCTGCGGC TGCAGGCAGA GCTGGAGACC 
AGTGAGCAGG TGCAGAGGGA TTTCGTGCGA CTGTCCCAGG CCCTGCAGGT GCGCCTAGAG 
CGGATCCGCC AGGCTGAGAC CCTGGAGCAA GTGCGCAGCA TCATGGATGA GGCGCCACTC 
ACGGACGTCA GGGACATCAA GGACACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079092.2
CDS	49..1758
Translation	MAAAAPVAADDDERRRRPGAALEDSRSQEGANGEAESGELSRLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSISSYEAQITALKQERQQQQQDCEEKERELGRLKQLLSRAYPLDSLEKQMEKAHEDSEKLREIVLPMEKEIEELKAKLLRAEELIQEIQRRPRHAPSLHGSTELLPLSRDPSPPLEPLEELSGDGGPAAEAFAHNCDDSASISSFSLGGGVGSSSSLPQSRQGLSPEQEETASLVSTGTLVPEGIYLPPPGYQLVPDTQWEQLQTEGRQLQKDLESVSRERDELQEGLRRSNEDCAKQMQVLLAQVQNSEQLLRTLQGTVSQAQERVQLQMAELVTTHKCLHHEVKRLNEENQGLRAEQLPSSAPQGSQQEQGEEESLPSSVPELQQLLCCTRQEARARLQAQEHGAERLRIEIVTLREALEEETVARASLEGQLRVQREETEVLEASLCSLRTEMERVQQEQSKAQLPDLLSEQRAKVLRLQAELETSEQVQRDFVRLSQALQVRLERIRQAETLEQVRSIMDEAPLTDVRDIKDT

Target ORF information:

RefSeq Version	NM_024816.2
Organism	Homo sapiens(human)
Definition	Homo sapiens rabaptin, RAB GTPase binding effector protein 2 (RABEP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024816.2

ORF Insert Sequence:

ATGGCGGCAG CTGCGCCGGT GGCCGCGGAC GACGATGAGC GGCGGCGGCG GCCGGGGGCT 
GCACTGGAGG ACTCCCGGTC CCAGGAAGGG GCAAATGGTG AGGCCGAGTC AGGTGAGCTC 
AGCCGGCTTC GGGCTGAGCT GGCAGGCGCC CTGGCAGAAA TGGAAACCAT GAAGGCTGTG 
GCAGAGGTGA GCGAGAGCAC GAAGGCCGAG GCTGTGGCTG CGGTGCAGCG GCAGTGCCAA 
GAGGAGGTGG CCTCGCTGCA GGCCATCCTG AAAGACTCCA TCAGCAGCTA TGAAGCCCAG 
ATCACCGCCC TGAAGCAGGA GCGACAGCAG CAGCAGCAGG ACTGTGAGGA GAAGGAGCGG 
GAGCTGGGCC GCCTGAAGCA GCTGCTGTCC CGGGCCTACC CCCTGGACTC CCTGGAGAAG 
CAGATGGAAA AGGCCCACGA GGACTCGGAG AAGCTGCGGG AGATCGTACT GCCCATGGAA 
AAGGAGATCG AGGAGCTGAA GGCGAAGCTG CTGAGGGCCG AGGAGCTGAT TCAGGAGATC 
CAGAGACGTC CCCGGCATGC CCCTTCCCTG CACGGCTCCA CGGAGTTGCT GCCCCTGTCC 
CGGGATCCAT CGCCCCCGCT GGAGCCTCTG GAGGAGCTGA GCGGAGATGG GGGTCCAGCC 
GCTGAGGCCT TCGCTCACAA CTGCGATGAC AGCGCCTCCA TCTCCTCCTT CTCCCTTGGC 
GGTGGGGTCG GCAGCAGCTC CTCCCTGCCC CAAAGCCGCC AGGGCCTGAG CCCTGAACAG 
GAAGAGACGG CCTCGCTGGT GTCTACGGGC ACCCTGGTTC CCGAGGGCAT CTACCTGCCC 
CCTCCTGGCT ACCAGCTCGT CCCAGACACT CAGTGGGAGC AGCTGCAGAC AGAGGGCCGA 
CAGCTGCAGA AGGACCTGGA GAGCGTCAGT CGCGAGCGGG ACGAGCTCCA AGAGGGCCTG 
AGACGGAGCA ATGAGGACTG TGCCAAGCAG ATGCAGGTGC TCCTGGCCCA GGTCCAGAAC 
TCAGAGCAGC TGCTGCGGAC CCTGCAAGGG ACCGTGAGCC AGGCCCAGGA GCGGGTGCAG 
CTGCAGATGG CGGAGCTGGT CACCACCCAC AAGTGCCTGC ACCATGAGGT AAAGCGGTTG 
AATGAGGAAA ACCAAGGGCT CCGGGCCGAG CAGCTGCCAT CCTCAGCCCC CCAGGGCTCG 
CAGCAGGAGC AGGGCGAGGA GGAATCACTG CCCAGCTCTG TGCCAGAGCT GCAGCAGCTG 
CTGTGCTGCA CGCGGCAAGA GGCGAGGGCC CGGCTGCAGG CCCAGGAGCA CGGGGCCGAG 
CGCCTGCGGA TCGAGATCGT GACGCTGCGG GAGGCTCTGG AGGAGGAGAC AGTGGCCAGG 
GCCAGCCTGG AGGGGCAGCT GAGGGTGCAG CGGGAGGAGA CAGAGGTGCT GGAGGCCTCC 
CTGTGCAGCC TGAGGACAGA GATGGAGCGG GTGCAGCAGG AACAGAGCAA GGCCCAGCTC 
CCAGACCTCC TCTCAGAACA GAGGGCCAAG GTGCTGCGGC TGCAGGCAGA GCTGGAGACC 
AGTGAGCAGG TGCAGAGGGA TTTCGTGCGA CTGTCCCAGG CCCTGCAGGT GCGCCTAGAG 
CGGATCCGCC AGGCTGAGAC CCTGGAGCAA GTGCGCAGCA TCATGGATGA GGCGCCACTC 
ACGGACGTCA GGGACATCAA GGACACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RABEP2 ( NM_024816.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079092.2 Homo sapiens rabaptin, RAB GTPase binding effector protein 2 (RABEP2), mRNA.

Price & Availability↑

CloneID	OHu17297
Clone ID Related Accession (Same CDS sequence)	NM_024816.2 , NM_024816.3
Accession Version	NM_024816.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1710bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	rab GTPase-binding effector protein 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC109460.3, AK026935.1 and BC046118.1. On Nov 24, 2018 this sequence version replaced NM_024816.2. ##Evidence-Data-START## Transcript exon combination :: AK026935.1, AK092299.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000358201.9/ ENSP00000350934.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCAG CTGCGCCGGT GGCCGCGGAC GACGATGAGC GGCGGCGGCG GCCGGGGGCT 
GCACTGGAGG ACTCCCGGTC CCAGGAAGGG GCAAATGGTG AGGCCGAGTC AGGTGAGCTC 
AGCCGGCTTC GGGCTGAGCT GGCAGGCGCC CTGGCAGAAA TGGAAACCAT GAAGGCTGTG 
GCAGAGGTGA GCGAGAGCAC GAAGGCCGAG GCTGTGGCTG CGGTGCAGCG GCAGTGCCAA 
GAGGAGGTGG CCTCGCTGCA GGCCATCCTG AAAGACTCCA TCAGCAGCTA TGAAGCCCAG 
ATCACCGCCC TGAAGCAGGA GCGACAGCAG CAGCAGCAGG ACTGTGAGGA GAAGGAGCGG 
GAGCTGGGCC GCCTGAAGCA GCTGCTGTCC CGGGCCTACC CCCTGGACTC CCTGGAGAAG 
CAGATGGAAA AGGCCCACGA GGACTCGGAG AAGCTGCGGG AGATCGTACT GCCCATGGAA 
AAGGAGATCG AGGAGCTGAA GGCGAAGCTG CTGAGGGCCG AGGAGCTGAT TCAGGAGATC 
CAGAGACGTC CCCGGCATGC CCCTTCCCTG CACGGCTCCA CGGAGTTGCT GCCCCTGTCC 
CGGGATCCAT CGCCCCCGCT GGAGCCTCTG GAGGAGCTGA GCGGAGATGG GGGTCCAGCC 
GCTGAGGCCT TCGCTCACAA CTGCGATGAC AGCGCCTCCA TCTCCTCCTT CTCCCTTGGC 
GGTGGGGTCG GCAGCAGCTC CTCCCTGCCC CAAAGCCGCC AGGGCCTGAG CCCTGAACAG 
GAAGAGACGG CCTCGCTGGT GTCTACGGGC ACCCTGGTTC CCGAGGGCAT CTACCTGCCC 
CCTCCTGGCT ACCAGCTCGT CCCAGACACT CAGTGGGAGC AGCTGCAGAC AGAGGGCCGA 
CAGCTGCAGA AGGACCTGGA GAGCGTCAGT CGCGAGCGGG ACGAGCTCCA AGAGGGCCTG 
AGACGGAGCA ATGAGGACTG TGCCAAGCAG ATGCAGGTGC TCCTGGCCCA GGTCCAGAAC 
TCAGAGCAGC TGCTGCGGAC CCTGCAAGGG ACCGTGAGCC AGGCCCAGGA GCGGGTGCAG 
CTGCAGATGG CGGAGCTGGT CACCACCCAC AAGTGCCTGC ACCATGAGGT AAAGCGGTTG 
AATGAGGAAA ACCAAGGGCT CCGGGCCGAG CAGCTGCCAT CCTCAGCCCC CCAGGGCTCG 
CAGCAGGAGC AGGGCGAGGA GGAATCACTG CCCAGCTCTG TGCCAGAGCT GCAGCAGCTG 
CTGTGCTGCA CGCGGCAAGA GGCGAGGGCC CGGCTGCAGG CCCAGGAGCA CGGGGCCGAG 
CGCCTGCGGA TCGAGATCGT GACGCTGCGG GAGGCTCTGG AGGAGGAGAC AGTGGCCAGG 
GCCAGCCTGG AGGGGCAGCT GAGGGTGCAG CGGGAGGAGA CAGAGGTGCT GGAGGCCTCC 
CTGTGCAGCC TGAGGACAGA GATGGAGCGG GTGCAGCAGG AACAGAGCAA GGCCCAGCTC 
CCAGACCTCC TCTCAGAACA GAGGGCCAAG GTGCTGCGGC TGCAGGCAGA GCTGGAGACC 
AGTGAGCAGG TGCAGAGGGA TTTCGTGCGA CTGTCCCAGG CCCTGCAGGT GCGCCTAGAG 
CGGATCCGCC AGGCTGAGAC CCTGGAGCAA GTGCGCAGCA TCATGGATGA GGCGCCACTC 
ACGGACGTCA GGGACATCAA GGACACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079092.2
CDS	76..1785
Translation	MAAAAPVAADDDERRRRPGAALEDSRSQEGANGEAESGELSRLRAELAGALAEMETMKAVAEVSESTKAEAVAAVQRQCQEEVASLQAILKDSISSYEAQITALKQERQQQQQDCEEKERELGRLKQLLSRAYPLDSLEKQMEKAHEDSEKLREIVLPMEKEIEELKAKLLRAEELIQEIQRRPRHAPSLHGSTELLPLSRDPSPPLEPLEELSGDGGPAAEAFAHNCDDSASISSFSLGGGVGSSSSLPQSRQGLSPEQEETASLVSTGTLVPEGIYLPPPGYQLVPDTQWEQLQTEGRQLQKDLESVSRERDELQEGLRRSNEDCAKQMQVLLAQVQNSEQLLRTLQGTVSQAQERVQLQMAELVTTHKCLHHEVKRLNEENQGLRAEQLPSSAPQGSQQEQGEEESLPSSVPELQQLLCCTRQEARARLQAQEHGAERLRIEIVTLREALEEETVARASLEGQLRVQREETEVLEASLCSLRTEMERVQQEQSKAQLPDLLSEQRAKVLRLQAELETSEQVQRDFVRLSQALQVRLERIRQAETLEQVRSIMDEAPLTDVRDIKDT

Target ORF information:

RefSeq Version	NM_024816.3
Organism	Homo sapiens(human)
Definition	Homo sapiens rabaptin, RAB GTPase binding effector protein 2 (RABEP2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024816.3

ORF Insert Sequence:

ATGGCGGCAG CTGCGCCGGT GGCCGCGGAC GACGATGAGC GGCGGCGGCG GCCGGGGGCT 
GCACTGGAGG ACTCCCGGTC CCAGGAAGGG GCAAATGGTG AGGCCGAGTC AGGTGAGCTC 
AGCCGGCTTC GGGCTGAGCT GGCAGGCGCC CTGGCAGAAA TGGAAACCAT GAAGGCTGTG 
GCAGAGGTGA GCGAGAGCAC GAAGGCCGAG GCTGTGGCTG CGGTGCAGCG GCAGTGCCAA 
GAGGAGGTGG CCTCGCTGCA GGCCATCCTG AAAGACTCCA TCAGCAGCTA TGAAGCCCAG 
ATCACCGCCC TGAAGCAGGA GCGACAGCAG CAGCAGCAGG ACTGTGAGGA GAAGGAGCGG 
GAGCTGGGCC GCCTGAAGCA GCTGCTGTCC CGGGCCTACC CCCTGGACTC CCTGGAGAAG 
CAGATGGAAA AGGCCCACGA GGACTCGGAG AAGCTGCGGG AGATCGTACT GCCCATGGAA 
AAGGAGATCG AGGAGCTGAA GGCGAAGCTG CTGAGGGCCG AGGAGCTGAT TCAGGAGATC 
CAGAGACGTC CCCGGCATGC CCCTTCCCTG CACGGCTCCA CGGAGTTGCT GCCCCTGTCC 
CGGGATCCAT CGCCCCCGCT GGAGCCTCTG GAGGAGCTGA GCGGAGATGG GGGTCCAGCC 
GCTGAGGCCT TCGCTCACAA CTGCGATGAC AGCGCCTCCA TCTCCTCCTT CTCCCTTGGC 
GGTGGGGTCG GCAGCAGCTC CTCCCTGCCC CAAAGCCGCC AGGGCCTGAG CCCTGAACAG 
GAAGAGACGG CCTCGCTGGT GTCTACGGGC ACCCTGGTTC CCGAGGGCAT CTACCTGCCC 
CCTCCTGGCT ACCAGCTCGT CCCAGACACT CAGTGGGAGC AGCTGCAGAC AGAGGGCCGA 
CAGCTGCAGA AGGACCTGGA GAGCGTCAGT CGCGAGCGGG ACGAGCTCCA AGAGGGCCTG 
AGACGGAGCA ATGAGGACTG TGCCAAGCAG ATGCAGGTGC TCCTGGCCCA GGTCCAGAAC 
TCAGAGCAGC TGCTGCGGAC CCTGCAAGGG ACCGTGAGCC AGGCCCAGGA GCGGGTGCAG 
CTGCAGATGG CGGAGCTGGT CACCACCCAC AAGTGCCTGC ACCATGAGGT AAAGCGGTTG 
AATGAGGAAA ACCAAGGGCT CCGGGCCGAG CAGCTGCCAT CCTCAGCCCC CCAGGGCTCG 
CAGCAGGAGC AGGGCGAGGA GGAATCACTG CCCAGCTCTG TGCCAGAGCT GCAGCAGCTG 
CTGTGCTGCA CGCGGCAAGA GGCGAGGGCC CGGCTGCAGG CCCAGGAGCA CGGGGCCGAG 
CGCCTGCGGA TCGAGATCGT GACGCTGCGG GAGGCTCTGG AGGAGGAGAC AGTGGCCAGG 
GCCAGCCTGG AGGGGCAGCT GAGGGTGCAG CGGGAGGAGA CAGAGGTGCT GGAGGCCTCC 
CTGTGCAGCC TGAGGACAGA GATGGAGCGG GTGCAGCAGG AACAGAGCAA GGCCCAGCTC 
CCAGACCTCC TCTCAGAACA GAGGGCCAAG GTGCTGCGGC TGCAGGCAGA GCTGGAGACC 
AGTGAGCAGG TGCAGAGGGA TTTCGTGCGA CTGTCCCAGG CCCTGCAGGT GCGCCTAGAG 
CGGATCCGCC AGGCTGAGAC CCTGGAGCAA GTGCGCAGCA TCATGGATGA GGCGCCACTC 
ACGGACGTCA GGGACATCAA GGACACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rab-GTPase binding effector protein 2 (RABEP2) is a primed substrate for Glycogen Synthase kinase-3 (GSK3).
Scientific reports7(1)17682(2017 Dec)
Logie L,Van Aalten L,Knebel A,Force T,Hastie CJ,MacLauchlan H,Campbell DG,Gourlay R,Prescott A,Davidson J,Fuller W,Sutherland C

SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling.
PloS one11(5)e0156081(2016)
Airik R,Schueler M,Airik M,Cho J,Ulanowicz KA,Porath JD,Hurd TW,Bekker-Jensen S,Schr?der JM,Andersen JS,Hildebrandt F

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
Nature genetics45(5)501-12(2013 May)
Berndt SI,Gustafsson S,M?gi R,Ganna A,Wheeler E,Feitosa MF,Justice AE,Monda KL,Croteau-Chonka DC,Day FR,Esko T,Fall T,Ferreira T,Gentilini D,Jackson AU,Luan J,Randall JC,Vedantam S,Willer CJ,Winkler TW,Wood AR,Workalemahu T,Hu YJ,Lee SH,Liang L,Lin DY,Min JL,Neale BM,Thorleifsson G,Yang J,Albrecht E,Amin N,Bragg-Gresham JL,Cadby G,den Heijer M,Eklund N,Fischer K,Goel A,Hottenga JJ,Huffman JE,Jarick I,Johansson ?,Johnson T,Kanoni S,Kleber ME,K?nig IR,Kristiansson K,Kutalik Z,Lamina C,Lecoeur C,Li G,Mangino M,McArdle WL,Medina-Gomez C,M?ller-Nurasyid M,Ngwa JS,Nolte IM,Paternoster L,Pechlivanis S,Perola M,Peters MJ,Preuss M,Rose LM,Shi J,Shungin D,Smith AV,Strawbridge RJ,Surakka I,Teumer A,Trip MD,Tyrer J,Van Vliet-Ostaptchouk JV,Vandenput L,Waite LL,Zhao JH,Absher D,Asselbergs FW,Atalay M,Attwood AP,Balmforth AJ,Basart H,Beilby J,Bonnycastle LL,Brambilla P,Bruinenberg M,Campbell H,Chasman DI,Chines PS,Collins FS,Connell JM,Cookson WO,de Faire U,de Vegt F,Dei M,Dimitriou M,Edkins S,Estrada K,Evans DM,Farrall M,Ferrario MM,Ferri?res J,Franke L,Frau F,Gejman PV,Grallert H,Gr?nberg H,Gudnason V,Hall AS,Hall P,Hartikainen AL,Hayward C,Heard-Costa NL,Heath AC,Hebebrand J,Homuth G,Hu FB,Hunt SE,Hypp?nen E,Iribarren C,Jacobs KB,Jansson JO,Jula A,K?h?nen M,Kathiresan S,Kee F,Khaw KT,Kivim?ki M,Koenig W,Kraja AT,Kumari M,Kuulasmaa K,Kuusisto J,Laitinen JH,Lakka TA,Langenberg C,Launer LJ,Lind L,Lindstr?m J,Liu J,Liuzzi A,Lokki ML,Lorentzon M,Madden PA,Magnusson PK,Manunta P,Marek D,M?rz W,Mateo Leach I,McKnight B,Medland SE,Mihailov E,Milani L,Montgomery GW,Mooser V,M?hleisen TW,Munroe PB,Musk AW,Narisu N,Navis G,Nicholson G,Nohr EA,Ong KK,Oostra BA,Palmer CN,Palotie A,Peden JF,Pedersen N,Peters A,Polasek O,Pouta A,Pramstaller PP,Prokopenko I,P?tter C,Radhakrishnan A,Raitakari O,Rendon A,Rivadeneira F,Rudan I,Saaristo TE,Sambrook JG,Sanders AR,Sanna S,Saramies J,Schipf S,Schreiber S,Schunkert H,Shin SY,Signorini S,Sinisalo J,Skrobek B,Soranzo N,Stan??kov? A,Stark K,Stephens JC,Stirrups K,Stolk RP,Stumvoll M,Swift AJ,Theodoraki EV,Thorand B,Tregouet DA,Tremoli E,Van der Klauw MM,van Meurs JB,Vermeulen SH,Viikari J,Virtamo J,Vitart V,Waeber G,Wang Z,Wid?n E,Wild SH,Willemsen G,Winkelmann BR,Witteman JC,Wolffenbuttel BH,Wong A,Wright AF,Zillikens MC,Amouyel P,Boehm BO,Boerwinkle E,Boomsma DI,Caulfield MJ,Chanock SJ,Cupples LA,Cusi D,Dedoussis GV,Erdmann J,Eriksson JG,Franks PW,Froguel P,Gieger C,Gyllensten U,Hamsten A,Harris TB,Hengstenberg C,Hicks AA,Hingorani A,Hinney A,Hofman A,Hovingh KG,Hveem K,Illig T,Jarvelin MR,J?ckel KH,Keinanen-Kiukaanniemi SM,Kiemeney LA,Kuh D,Laakso M,Lehtim?ki T,Levinson DF,Martin NG,Metspalu A,Morris AD,Nieminen MS,Nj?lstad I,Ohlsson C,Oldehinkel AJ,Ouwehand WH,Palmer LJ,Penninx B,Power C,Province MA,Psaty BM,Qi L,Rauramaa R,Ridker PM,Ripatti S,Salomaa V,Samani NJ,Snieder H,S?rensen TI,Spector TD,Stefansson K,T?njes A,Tuomilehto J,Uitterlinden AG,Uusitupa M,van der Harst P,Vollenweider P,Wallaschofski H,Wareham NJ,Watkins H,Wichmann HE,Wilson JF,Abecasis GR,Assimes TL,Barroso I,Boehnke M,Borecki IB,Deloukas P,Fox CS,Frayling T,Groop LC,Haritunian T,Heid IM,Hunter D,Kaplan RC,Karpe F,Moffatt MF,Mohlke KL,O'Connell JR,Pawitan Y,Schadt EE,Schlessinger D,Steinthorsdottir V,Strachan DP,Thorsteinsdottir U,van Duijn CM,Visscher PM,Di Blasio AM,Hirschhorn JN,Lindgren CM,Morris AP,Meyre D,Scherag A,McCarthy MI,Speliotes EK,North KE,Loos RJ,Ingelsson E

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature491(7422)119-24(2012 Nov)
Jostins L,Ripke S,Weersma RK,Duerr RH,McGovern DP,Hui KY,Lee JC,Schumm LP,Sharma Y,Anderson CA,Essers J,Mitrovic M,Ning K,Cleynen I,Theatre E,Spain SL,Raychaudhuri S,Goyette P,Wei Z,Abraham C,Achkar JP,Ahmad T,Amininejad L,Ananthakrishnan AN,Andersen V,Andrews JM,Baidoo L,Balschun T,Bampton PA,Bitton A,Boucher G,Brand S,B?ning C,Cohain A,Cichon S,D'Amato M,De Jong D,Devaney KL,Dubinsky M,Edwards C,Ellinghaus D,Ferguson LR,Franchimont D,Fransen K,Gearry R,Georges M,Gieger C,Glas J,Haritunians T,Hart A,Hawkey C,Hedl M,Hu X,Karlsen TH,Kupcinskas L,Kugathasan S,Latiano A,Laukens D,Lawrance IC,Lees CW,Louis E,Mahy G,Mansfield J,Morgan AR,Mowat C,Newman W,Palmieri O,Ponsioen CY,Potocnik U,Prescott NJ,Regueiro M,Rotter JI,Russell RK,Sanderson JD,Sans M,Satsangi J,Schreiber S,Simms LA,Sventoraityte J,Targan SR,Taylor KD,Tremelling M,Verspaget HW,De Vos M,Wijmenga C,Wilson DC,Winkelmann J,Xavier RJ,Zeissig S,Zhang B,Zhang CK,Zhao H,,Silverberg MS,Annese V,Hakonarson H,Brant SR,Radford-Smith G,Mathew CG,Rioux JD,Schadt EE,Daly MJ,Franke A,Parkes M,Vermeire S,Barrett JC,Cho JH

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RABEP2 cDNA ORF clone, Homo sapiens(human)

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ORF Insert Sequence:

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ORF Insert Sequence:

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