| Gene Symbol | SPRY4 |
| Entrez Gene ID | 81848 |
| Full Name | sprouty RTK signaling antagonist 4 |
| Synonyms | HH17 |
| General protein information |
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| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a member of a family of cysteine- and proline-rich proteins. The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. Activity of this protein impairs the formation of active GTP-RAS. Nucleotide variation in this gene has been associated with hypogonadotropic hypogonadism 17 with or without anosmia. Alternative splicing results in a multiple transcript variants. [provided by RefSeq, Jun 2014]. |
| Disorder MIM: | |
| Disorder Html: | Hypogonadotropic hypogonadism 17 with or without anosmia, 615266 (3) |

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