Gene Symbol | RNGTT |
Entrez Gene ID | 8732 |
Full Name | RNA guanylyltransferase and 5'-phosphatase |
Synonyms | CAP1A,HCE,HCE1,hCAP |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » RNGTT cDNA ORF clone
gRNAs
Gene Symbol | RNGTT |
Entrez Gene ID | 8732 |
Full Name | RNA guanylyltransferase and 5'-phosphatase |
Synonyms | CAP1A,HCE,HCE1,hCAP |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001286426.1 | NP_001273355.1 | mRNA-capping enzyme isoform b |
NM_001286428.2 | NP_001273357.1 | mRNA-capping enzyme isoform c |
XM_017011401.2 | XP_016866890.1 | mRNA-capping enzyme isoform X1 |
NM_003800.4 | NP_003791.3 | mRNA-capping enzyme isoform a |
XM_017011402.2 | XP_016866891.1 | mRNA-capping enzyme isoform X2 |
NM_001286428.1 | NP_001273357.1 | mRNA-capping enzyme isoform c |
XM_017011402.1 | XP_016866891.1 | mRNA-capping enzyme isoform X2 |
XM_017011401.1 | XP_016866890.1 | mRNA-capping enzyme isoform X1 |
NM_001286426.2 | NP_001273355.1 | mRNA-capping enzyme isoform b |
NM_003800.5 | NP_003791.3 | mRNA-capping enzyme isoform a |
Canis lupus familiaris (dog) | RNGTT | XP_539035.3 |
Bos taurus (cattle) | RNGTT | NP_001039550.1 |
Mus musculus (house mouse) | Rngtt | NP_036014.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005142 | XP_314026.4 |
Caenorhabditis elegans (roundworm) | cel-1 | NP_001020979.1 |
Arabidopsis thaliana (thale cress) | AT3G09100 | NP_974263.1 |
Arabidopsis thaliana (thale cress) | AT5G01290 | NP_195749.2 |
Xenopus tropicalis (tropical clawed frog) | rngtt | NP_001001222.1 |
Pan troglodytes (chimpanzee) | RNGTT | XP_518633.3 |
Arabidopsis thaliana (thale cress) | AT5G28210 | NP_198173.1 |
Homo sapiens (human) | RNGTT | NP_003791.3 |
Danio rerio (zebrafish) | rngtt | NP_998032.1 |
Oryza sativa (rice) | Os12g0193200 | NP_001066345.1 |
Rattus norvegicus (Norway rat) | Rngtt | NP_001101393.1 |
Gallus gallus (chicken) | RNGTT | XP_419843.2 |
Drosophila melanogaster (fruit fly) | mRNA-cap | NP_572952.1 |
c-Myc deregulation induces mRNA capping enzyme dependency.
Lombardi O, Varshney D, Phillips NM, Cowling VH
Oncotarget7(50)82273-82288(2016 Dec)
The cytoplasmic capping complex assembles on adapter protein nck1 bound to the proline-rich C-terminus of Mammalian capping enzyme.
Mukherjee C, Bakthavachalu B, Schoenberg DR
PLoS biology12(8)e1001933(2014 Aug)
The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme.
Picard-Jean F, Bougie I, Shuto S, Bisaillon M
PloS one8(1)e54621(2013)
Structure of the guanylyltransferase domain of human mRNA capping enzyme.
Chu C, Das K, Tyminski JR, Bauman JD, Guan R, Qiu W, Montelione GT, Arnold E, Shatkin AJ
Proceedings of the National Academy of Sciences of the United States of America108(25)10104-8(2011 Jun)
Genome-wide association of lipid-lowering response to statins in combined study populations.
Barber MJ, Mangravite LM, Hyde CL, Chasman DI, Smith JD, McCarty CA, Li X, Wilke RA, Rieder MJ, Williams PT, Ridker PM, Chatterjee A, Rotter JI, Nickerson DA, Stephens M, Krauss RM
PloS one5(3)e9763(2010 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results identify a new domain of CE that is specific to its function in cytoplasmic capping, and a new role for Nck1 in regulating gene expression through its role as the scaffold for assembly of the cytoplasmic capping complex.
Title: The cytoplasmic capping complex assembles on adapter protein nck1 bound to the proline-rich C-terminus of Mammalian capping enzyme.
Our biochemical studies provide the first insight that MZP can inhibit the formation of the RNA cap structure catalyzed by HCE.
Title: The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme.
Data show that human capping enzyme residues 229-567 comprise the minimum enzymatically active human GTase (hGTase) domain and determine the structure by X-ray crystallography.
Title: Structure of the guanylyltransferase domain of human mRNA capping enzyme.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
The following RNGTT gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RNGTT cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
Online Only Promotion
Up to 50% OFF! Starting
from $49/clone
CloneID | OHu14323![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_003800.4 , NM_003800.5 | |
Accession Version | NM_003800.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-02 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP256840.1, AB009022.1, BX537450.1, BC019954.1, AI193199.1 and BP396964.1. On Nov 5, 2013 this sequence version replaced NM_003800.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.170631.1, SRR1803613.170068.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_003791.3 |
CDS | 221..2014 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu14323![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_003800.4 , NM_003800.5 | |
Accession Version | NM_003800.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1794bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-02 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP256840.1, AB009022.1, BX537450.1, BC019954.1, AI193199.1 and BP396964.1. On Nov 22, 2018 this sequence version replaced NM_003800.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.170631.1, SRR1803613.170068.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000369485.9/ ENSP00000358497.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_003791.3 |
CDS | 210..2003 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05556 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286426.1 , NM_001286426.2 | |
Accession Version | NM_001286426.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP256840.1, AB009023.1, BX537450.1, BC019954.1, AI193199.1 and BP396964.1. On Nov 5, 2013 this sequence version replaced XM_005248767.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.46989.1, SRR1660809.107814.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273355.1 |
CDS | 221..1945 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05556 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286426.1 , NM_001286426.2 | |
Accession Version | NM_001286426.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1725bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP256840.1, AB009023.1, BX537450.1, BC019954.1, AI193199.1 and BP396964.1. On May 31, 2019 this sequence version replaced NM_001286426.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803613.46989.1, SRR1660809.238709.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273355.1 |
CDS | 210..1934 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05558 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286428.2 , NM_001286428.1 | |
Accession Version | NM_001286428.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK299777.1, BX537450.1, BC019954.1, AI193199.1 and BP396964.1. On May 31, 2019 this sequence version replaced NM_001286428.1. Transcript Variant: This variant (3) differs in its 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream in-frame start codon, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299777.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCTTGT TGGTGGACCT GACAAATACT TCAAGGTTCT ATGACCGAAA TGACATAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273357.1 |
CDS | 280..1824 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCTTGT TGGTGGACCT GACAAATACT TCAAGGTTCT ATGACCGAAA TGACATAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05558 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286428.2 , NM_001286428.1 | |
Accession Version | NM_001286428.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1545bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-29 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP256840.1, AK299777.1, BX537450.1, BC019954.1, AI193199.1 and BP396964.1. Transcript Variant: This variant (3) differs in its 5' UTR, lacks a portion of the 5' coding region, initiates translation at a downstream in-frame start codon, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK299777.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCTTGT TGGTGGACCT GACAAATACT TCAAGGTTCT ATGACCGAAA TGACATAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273357.1 |
CDS | 291..1835 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGGCTTGT TGGTGGACCT GACAAATACT TCAAGGTTCT ATGACCGAAA TGACATAGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu96867 | |
Clone ID Related Accession (Same CDS sequence) | XM_017011401.2 , XM_017011401.1 | |
Accession Version | XM_017011401.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1812bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017011401.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016866890.1 |
CDS | 191..2002 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu96867 | |
Clone ID Related Accession (Same CDS sequence) | XM_017011401.2 , XM_017011401.1 | |
Accession Version | XM_017011401.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1812bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016866890.1 |
CDS | 308..2119 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu96868 | |
Clone ID Related Accession (Same CDS sequence) | XM_017011402.2 , XM_017011402.1 | |
Accession Version | XM_017011402.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1791bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017011402.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016866891.1 |
CDS | 191..1981 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu96868 | |
Clone ID Related Accession (Same CDS sequence) | XM_017011402.2 , XM_017011402.1 | |
Accession Version | XM_017011402.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1791bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | mRNA-capping enzyme isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016866891.1 |
CDS | 308..2098 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCTCACA ACAAGATCCC GCCGCGGTGG CTGAACTGTC CCCGGCGCGG CCAGCCGGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
c-Myc deregulation induces mRNA capping enzyme dependency. |
The cytoplasmic capping complex assembles on adapter protein nck1 bound to the proline-rich C-terminus of Mammalian capping enzyme. |
The immunosuppressive agent mizoribine monophosphate is an inhibitor of the human RNA capping enzyme. |
Structure of the guanylyltransferase domain of human mRNA capping enzyme. |
Genome-wide association of lipid-lowering response to statins in combined study populations. |