Gene Symbol | CD33 |
Entrez Gene ID | 945 |
Full Name | CD33 molecule |
Synonyms | SIGLEC-3,SIGLEC3,p67 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » CD33 cDNA ORF clone
Gene Symbol | CD33 |
Entrez Gene ID | 945 |
Full Name | CD33 molecule |
Synonyms | SIGLEC-3,SIGLEC3,p67 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_017027508.1 | XP_016882997.1 | myeloid cell surface antigen CD33 isoform X1 |
NM_001082618.2 | NP_001076087.1 | myeloid cell surface antigen CD33 isoform 2 |
XM_011527531.2 | XP_011525833.1 | myeloid cell surface antigen CD33 isoform X1 |
NM_001177608.1 | NP_001171079.1 | myeloid cell surface antigen CD33 isoform 3 precursor |
XM_011527532.2 | XP_011525834.1 | myeloid cell surface antigen CD33 isoform X3 |
NM_001772.3 | NP_001763.3 | myeloid cell surface antigen CD33 isoform 1 precursor |
XM_017027509.1 | XP_016882998.1 | myeloid cell surface antigen CD33 isoform X2 |
XM_017027510.1 | XP_016882999.1 | myeloid cell surface antigen CD33 isoform X4 |
NM_001177608.2 | NP_001171079.1 | myeloid cell surface antigen CD33 isoform 3 precursor |
XM_011527532.1 | XP_011525834.1 | myeloid cell surface antigen CD33 isoform X1 |
NM_001082618.1 | NP_001076087.1 | myeloid cell surface antigen CD33 isoform 2 |
NM_001772.4 | NP_001763.3 | myeloid cell surface antigen CD33 isoform 1 precursor |
CD33 splicing SNP regulates expression levels of CD33 in normal regenerating monocytes in AML patients.
Lamba JK, Voigt AP, Chauhan L, Shin M, Aplenc R, Eidenschink Brodersen L, Gamis AS, Meshinchi S, Loken MR
Leukemia & lymphoma1-4(2018 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data suggest that two SNPs in CD33 (rs3865444A, rs12459419T) that are protective of Alzheimer disease result in splice variants (CD33M, CD33m); CD33M localizes predominantly at cell surface in macrophage cell line; CD33m is primary intracellular form in neutrophils and a microglia cell line; intracellular CD33m accumulates in peroxisomes; activation of macrophages/neutrophils does not mobilize CD33m to cell surface.
Title: The Alzheimer's disease-protective CD33 splice variant mediates adaptive loss of function via diversion to an intracellular pool.
patients with the CC genotype for rs12459419 have a substantial response to Gemtuzumab Ozogamicin, making this a potential biomarker for the selection of patients with a likelihood of significant response to Gemtuzumab Ozogamicin.
Title: CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.
In cutaneous diffuse large b-cell lymphoma, a considerable proportion of CD33(+) myeloid-derived suppressor cells (MDSCs) with PD-L1 coexpression was admixed. Tumor cells expressed CD33 to variable degrees (2% to 60%). We propose that PD-L1(+) tumor cells and PD-L1(+) MDSCs shield the tumor against PD-1(+) tumor-infiltrating lymphocytes, consequently leading to inhibition and diminution of tumor-infiltrating lymphocytes.
Title: Tumor Microenvironment and Checkpoint Molecules in Primary Cutaneous Diffuse Large B-Cell Lymphoma-New Therapeutic Targets.
The use of CD33(+)CD11b(+)HLA-DR(-) cells as a predictive and prognostic biomarker.
Title: Clinical Significance of Circulating CD33+CD11b+HLA-DR- Myeloid Cells in Patients with Stage IV Melanoma Treated with Ipilimumab.
High efficacy of CD33/CD3 TandAbs in various preclinical models of human AML.
Title: Characterization of CD33/CD3 Tetravalent Bispecific Tandem Diabodies (TandAbs) for the Treatment of Acute Myeloid Leukemia.
The following CD33 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD33 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu17282 | |
Clone ID Related Accession (Same CDS sequence) | XM_011527532.2 , NM_001772.3 , XM_011527532.1 , NM_001772.4 | |
Accession Version | NM_001772.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-02 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP303860.1, BC028152.1 and AW007749.1. On Mar 14, 2007 this sequence version replaced NM_001772.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1), also known as CD33M. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M23197.1, ERR279873.843.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001763.3 |
CDS | 41..1135 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001772.3 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu17282 | |
Clone ID Related Accession (Same CDS sequence) | XM_011527532.2 , NM_001772.3 , XM_011527532.1 , NM_001772.4 | |
Accession Version | NM_001772.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-30 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP303860.1, BC028152.1 and AW007749.1. On Nov 23, 2018 this sequence version replaced NM_001772.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1), also known as CD33M. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.990782.1, SRR5189658.70557.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000262262.5/ ENSP00000262262.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001763.3 |
CDS | 40..1134 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001772.4 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu17386 | |
Clone ID Related Accession (Same CDS sequence) | NM_001082618.2 , NM_001082618.1 | |
Accession Version | NM_001082618.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-03 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP303860.1, AY162464.1 and AW007749.1. On Jun 1, 2019 this sequence version replaced NM_001082618.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2, also known as CD33m), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DRR138517.1083234.1, AY162464.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGACT TGACCCACAG GCCCAAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076087.1 |
CDS | 40..753 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001082618.2 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGACT TGACCCACAG GCCCAAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu17386 | |
Clone ID Related Accession (Same CDS sequence) | NM_001082618.2 , NM_001082618.1 | |
Accession Version | NM_001082618.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 714bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-10-19 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP303860.1, AY162464.1 and AW007749.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2, also known as CD33m), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY162464.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGACT TGACCCACAG GCCCAAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001076087.1 |
CDS | 41..754 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001082618.1 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGACT TGACCCACAG GCCCAAAATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu17282 | |
Clone ID Related Accession (Same CDS sequence) | XM_011527532.2 , NM_001772.3 , XM_011527532.1 , NM_001772.4 | |
Accession Version | XM_011527532.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527532.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011525834.1 |
CDS | 1078..2172 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011527532.2 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu17282 | |
Clone ID Related Accession (Same CDS sequence) | XM_011527532.2 , NM_001772.3 , XM_011527532.1 , NM_001772.4 | |
Accession Version | XM_011527532.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-11 | |
Organism | Homo sapiens(Human) | |
Product | myeloid cell surface antigen CD33 isoform X1 | |
Comment |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011525834.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011527532.1 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu17567 | |
Clone ID Related Accession (Same CDS sequence) | NM_001177608.1 , NM_001177608.2 | |
Accession Version | NM_001177608.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 933bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-21 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP295158.1, AK309558.1 and AK304810.1. Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304810.1, AK309558.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001171079.1 |
CDS | 41..973 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001177608.1 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu17567 | |
Clone ID Related Accession (Same CDS sequence) | NM_001177608.1 , NM_001177608.2 | |
Accession Version | NM_001177608.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 933bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-03 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP295158.1, AK309558.1 and AK304810.1. On May 31, 2019 this sequence version replaced NM_001177608.1. Transcript Variant: This variant (3) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK304810.1, AK309558.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001171079.1 |
CDS | 40..972 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001177608.2 |
1 | ATGCCGCTGC TGCTACTGCT GCCCCTGCTG TGGGCAGGGG CCCTGGCTAT GGATCCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu56721 | |
Clone ID Related Accession (Same CDS sequence) | XM_017027508.1 , XM_011527531.2 | |
Accession Version | XM_017027508.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016882997.1 |
CDS | 1089..2345 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017027508.1 |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu56721 | |
Clone ID Related Accession (Same CDS sequence) | XM_017027508.1 , XM_011527531.2 | |
Accession Version | XM_011527531.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1257bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011527531.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011525833.1 |
CDS | 953..2209 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011527531.2 |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu88842 | |
Clone ID Related Accession (Same CDS sequence) | XM_017027509.1 | |
Accession Version | XM_017027509.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1209bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016882998.1 |
CDS | 1041..2249 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017027509.1 |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu88843 | |
Clone ID Related Accession (Same CDS sequence) | XM_017027510.1 | |
Accession Version | XM_017027510.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | myeloid cell surface antigen CD33 isoform X4 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016882999.1 |
CDS | 1041..1916 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017027510.1 |
1 | ATGGATCTAG GTGAGGCTGC GACTCGGGCC AGGCCAGCAG TGATCAGCCC TGGTGTAAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CD33 splicing SNP regulates expression levels of CD33 in normal regenerating monocytes in AML patients. |