Gene Symbol | INPPL1 |
Entrez Gene ID | 16332 |
Full Name | inositol polyphosphate phosphatase-like 1 |
Synonyms | 51C,SHIP2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
ORF » Species Summary » Mus musculus » INPPL1 cDNA ORF clone
Gene Symbol | INPPL1 |
Entrez Gene ID | 16332 |
Full Name | inositol polyphosphate phosphatase-like 1 |
Synonyms | 51C,SHIP2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(House mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006507392.3 | XP_006507455.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2 |
XM_011241682.1 | XP_011239984.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 |
XM_011241682.3 | XP_011239984.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 |
XM_011241682.2 | XP_011239984.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 |
XM_017321991.1 | XP_017177480.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 |
NM_001122739.1 | NP_001116211.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 |
XM_030242165.1 | XP_030098025.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2 |
XM_006507391.3 | XP_006507454.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 |
NM_010567.2 | NP_034697.2 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 |
XM_006507391.2 | XP_006507454.1 | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 |
Homo sapiens (human) | INPPL1 | NP_001558.3 |
Pan troglodytes (chimpanzee) | INPPL1 | XP_508622.2 |
INPPL1 | XP_001114794.1 | |
Mus musculus (house mouse) | Inppl1 | NP_001116211.1 |
Canis lupus familiaris (dog) | INPPL1 | XP_542327.2 |
Bos taurus (cattle) | INPPL1 | NP_001178105.1 |
Rattus norvegicus (Norway rat) | Inppl1 | NP_075233.1 |
Danio rerio (zebrafish) | inppl1a | NP_001034893.1 |
Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase-Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance.
Watt NT, Gage MC, Patel PA, Viswambharan H, Sukumar P, Galloway S, Yuldasheva NY, Imrie H, Walker AMN, Griffin KJ, Makava N, Skromna A, Bridge K, Beech DJ, Schurmans S, Wheatcroft SB, Kearney MT, Cubbon RM
Diabetes66(11)2808-2821(2017 11)
Inhibition of SHIP2 in CD2AP-deficient podocytes ameliorates reactive oxygen species generation but aggravates apoptosis.
Saurus P, Tolvanen TA, Lindfors S, Kuusela S, Holth?fer H, Lehtonen E, Lehtonen S
Scientific reports7(1)10731(2017 Sep)
The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins.
Sayyed SG, Jouret F, Vermeersch M, P?rez-Morga D, Schurmans S
Kidney international92(1)125-139(2017 Jul)
Fc?RIIb-SHIP2 axis links A? to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.
Kam TI, Park H, Gwon Y, Song S, Kim SH, Moon SW, Jo DG, Jung YK
eLife5(2016 11)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
data suggest that endothelial SHIP2 is required to maintain normal systemic glucose homeostasis and prevent oxidative stress-induced endothelial dysfunction.
Title: Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase-Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance.
The authors concluded that the FcgammaRIIb-SHIP2 axis links Abeta neurotoxicity to tau pathology by dysregulating phosphoinositide metabolism, providing insight into therapeutic potential against Alzheimer's disease.
Title: Fc?RIIb-SHIP2 axis links A? to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model.
These findings suggest that palmitate contributes to SHIP2 overexpression in skeletal muscle via the mechanisms involving the activation of ceramide-JNK and NF-kappaB pathways.
Title: Palmitate induces SHIP2 expression via the ceramide-mediated activation of NF-?B, and JNK in skeletal muscle cells.
results suggest that SHIP2 contributes to the regulation of food intake mainly via the attenuation of insulin signalling in the hypothalamus of mice
Title: SH2-containing inositol 5'-phosphatase 2 selectively impairs hypothalamic insulin signalling and regulation of food intake in mice.
The catalytically-inactive Ship2 mutant protein in a context of reduced PtdIns(4,5)P2 3-kinase activity.
Title: Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse.
The following INPPL1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the INPPL1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | NM_001122739.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-20 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY016096.1, AK133359.1, BC063080.1 and CX208125.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK133359.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001116211.1 |
CDS | 304..4077 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001122739.1 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | NM_010567.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-20 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY060328.1, BC063080.1 and CX208125.1. On Mar 18, 2008 this sequence version replaced NM_010567.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF162781.1, BC063080.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_034697.2 |
CDS | 538..4311 |
Translation |
Target ORF information:
Target ORF information:
|
NM_010567.2 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | XM_011241682.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 | |
Comment |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239984.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241682.1 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | XM_011241682.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011241682.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239984.1 |
CDS | 337..4110 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241682.3 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | XM_011241682.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011241682.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011239984.1 |
CDS | 328..4101 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011241682.2 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | XM_017321991.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177480.1 |
CDS | 216..3989 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017321991.1 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | XM_006507391.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507391.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507454.1 |
CDS | 842..4615 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507391.3 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17680 | |
Clone ID Related Accession (Same CDS sequence) | XM_011241682.1 , XM_011241682.3 , XM_011241682.2 , XM_017321991.1 , NM_001122739.1 , XM_006507391.3 , NM_010567.2 , XM_006507391.2 | |
Accession Version | XM_006507391.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-08 | |
Organism | Mus musculus(House mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X1 | |
Comment |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507454.1 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507391.2 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39328 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507392.3 , XM_030242165.1 | |
Accession Version | XM_030242165.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3552bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030098025.1 |
CDS | 203..3754 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030242165.1 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39328 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507392.3 , XM_030242165.1 | |
Accession Version | XM_006507392.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3552bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507392.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507455.1 |
CDS | 842..4393 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507392.3 |
1 | ATGGCCTCAG TGTGTGGGAC ACCGAGTCCC GGGGGTGCGC TAGGCAGCCC GGCCCCAGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Endothelial SHIP2 Suppresses Nox2 NADPH Oxidase-Dependent Vascular Oxidative Stress, Endothelial Dysfunction, and Systemic Insulin Resistance. |
Inhibition of SHIP2 in CD2AP-deficient podocytes ameliorates reactive oxygen species generation but aggravates apoptosis. |
The lipid 5-phoshatase SHIP2 controls renal brush border ultrastructure and function by regulating the activation of ERM proteins. |
Fc?RIIb-SHIP2 axis links A? to tau pathology by disrupting phosphoinositide metabolism in Alzheimer's disease model. |