| Gene Symbol | Scin |
| Entrez Gene ID | 20259 |
| Full Name | scinderin |
| Synonyms | AW545522,adseverin |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
The following Scin gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Scin cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu03575 | |
| Clone ID Related Accession (Same CDS sequence) | NM_009132.2 | |
| Accession Version | NM_009132.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1848bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-11-15 | |
| Organism | Mus musculus(house mouse) | |
| Product | adseverin isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY201136.1, Y13971.1 and AK136080.1. On Apr 2, 2009 this sequence version replaced NM_009132.1. Transcript Variant: This variant (2) lacks two exons in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Y13971.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGCAGG AGCTGCAGCA CCCCGAGTTC GCGCGCGCAG GCCAGCAGGC TGGGCTGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_033158.2 |
| CDS | 121..1968 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_009132.2 |
1 | ATGGCGCAGG AGCTGCAGCA CCCCGAGTTC GCGCGCGCAG GCCAGCAGGC TGGGCTGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu07259 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001146196.1 | |
| Accession Version | NM_001146196.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2148bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-27 | |
| Organism | Mus musculus(house mouse) | |
| Product | adseverin isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY201136.1, BC063328.1 and Y13971.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC063328.1, AK173295.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGCGCAGG AGCTGCAGCA CCCCGAGTTC GCGCGCGCAG GCCAGCAGGC TGGGCTGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001139668.1 |
| CDS | 121..2268 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001146196.1 |
1 | ATGGCGCAGG AGCTGCAGCA CCCCGAGTTC GCGCGCGCAG GCCAGCAGGC TGGGCTGCAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Deletion of Adseverin in Osteoclasts Affects Cell Structure But Not Bone Metabolism. |
Adseverin mediates RANKL-induced osteoclastogenesis by regulating NFATc1. |
Adseverin plays a role in osteoclast differentiation and periodontal disease-mediated bone loss. |
The actin binding protein adseverin regulates osteoclastogenesis. |
