Gene Symbol | Sms |
Entrez Gene ID | 20603 |
Full Name | spermine synthase |
Synonyms | AI427066,Gy,SPMSY,SpmST,gyro |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Sms cDNA ORF clone
gRNAs
Gene Symbol | Sms |
Entrez Gene ID | 20603 |
Full Name | spermine synthase |
Synonyms | AI427066,Gy,SPMSY,SpmST,gyro |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_009214.3 | NP_033240.3 | spermine synthase |
NM_009214.4 | NP_033240.3 | spermine synthase isoform 1 |
XM_006528775.3 | XP_006528838.1 | spermine synthase isoform X1 |
NM_001359185.1 | NP_001346114.1 | spermine synthase isoform 2 |
Homo sapiens (human) | SMS | NP_004586.2 |
Pan troglodytes (chimpanzee) | SMS | XP_001142843.3 |
SMS | XP_001086702.2 | |
Gallus gallus (chicken) | SMS | NP_001025974.1 |
Canis lupus familiaris (dog) | SMS | XP_537978.3 |
Drosophila melanogaster (fruit fly) | CG4300 | NP_729798.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005325 | XP_315341.4 |
Mus musculus (house mouse) | Sms | NP_033240.3 |
Mus musculus (house mouse) | Gm14680 | XP_001473484.1 |
Rattus norvegicus (Norway rat) | Sms | NP_001029071.1 |
Xenopus tropicalis (tropical clawed frog) | sms | NP_001245351.1 |
Bos taurus (cattle) | SMS | NP_001030548.1 |
Danio rerio (zebrafish) | sms | NP_571831.1 |
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.
Adissu HA, Estabel J, Sunter D, Tuck E, Hooks Y, Carragher DM, Clarke K, Karp NA, , Newbigging S, Jones N, Morikawa L, White JK, McKerlie C
Disease models & mechanisms7(5)515-24(2014 May)
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes.
White JK, Gerdin AK, Karp NA, Ryder E, Buljan M, Bussell JN, Salisbury J, Clare S, Ingham NJ, Podrini C, Houghton R, Estabel J, Bottomley JR, Melvin DG, Sunter D, Adams NC, , Tannahill D, Logan DW, Macarthur DG, Flint J, Mahajan VB, Tsang SH, Smyth I, Watt FM, Skarnes WC, Dougan G, Adams DJ, Ramirez-Solis R, Bradley A, Steel KP
Cell154(2)452-64(2013 Jul)
Spermine synthase.
Pegg AE, Michael AJ
Cellular and molecular life sciences : CMLS67(1)113-21(2010 Jan)
Mouse models to investigate the function of spermine.
Pegg AE, Wang X
Communicative & integrative biology2(3)271-4(2009 May)
Transcriptomic analysis of polyamine-related genes and polyamine levels in placenta, yolk sac and fetus during the second half of mouse pregnancy.
Lopez-Garcia C, Lopez-Contreras AJ, Cremades A, Castells MT, Pe?afiel R
Placenta30(3)241-9(2009 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
alpha-difluoromethylornithine treatment of control mice or Gy-CAG/SpmS had no effect on balance
Title: Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine.
regulation of spermine synthase content is not required for spermine synthesis, which is needed for normal growth, viability, and fertility in male mice
Title: Spermine synthesis is required for normal viability, growth, and fertility in the mouse.
The following Sms gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Sms cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu56622 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528775.3 , NM_001359185.1 | |
Accession Version | NM_001359185.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-24 | |
Organism | Mus musculus(house mouse) | |
Product | spermine synthase isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL663072.12. On Dec 23, 2017 this sequence version replaced XM_006528775.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGACAGAGT CAGTGCACAC CTGGCAGGAC CATGGATATT TAGCAACTTA CACGAACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001346114.1 |
CDS | 131..1129 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGACAGAGT CAGTGCACAC CTGGCAGGAC CATGGATATT TAGCAACTTA CACGAACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu56622 | |
Clone ID Related Accession (Same CDS sequence) | XM_006528775.3 , NM_001359185.1 | |
Accession Version | XM_006528775.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 999bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | spermine synthase isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006528775.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACAGAGT CAGTGCACAC CTGGCAGGAC CATGGATATT TAGCAACTTA CACGAACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006528838.1 |
CDS | 434..1432 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGACAGAGT CAGTGCACAC CTGGCAGGAC CATGGATATT TAGCAACTTA CACGAACAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13002 | |
Clone ID Related Accession (Same CDS sequence) | NM_009214.3 , NM_009214.4 | |
Accession Version | NM_009214.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-04-28 | |
Organism | Mus musculus(House mouse) | |
Product | spermine synthase | |
Comment | VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK011542.1, AK017775.1, AK166665.1 and AK049787.1. On Dec 2, 2006 this sequence version replaced NM_009214.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK049787.1, AK166665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCAGCAG CAAGACACAG CACGCTCGAC TTCAAGCTCG GCGCCAAAGC TGATGGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033240.3 |
CDS | 94..1194 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCAG CAAGACACAG CACGCTCGAC TTCAAGCTCG GCGCCAAAGC TGATGGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu13002 | |
Clone ID Related Accession (Same CDS sequence) | NM_009214.3 , NM_009214.4 | |
Accession Version | NM_009214.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1101bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-25 | |
Organism | Mus musculus(house mouse) | |
Product | spermine synthase isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC058688.1 and AL663072.12. On Dec 23, 2017 this sequence version replaced NM_009214.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC058688.1, AK166665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164137 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCAGCAG CAAGACACAG CACGCTCGAC TTCAAGCTCG GCGCCAAAGC TGATGGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_033240.3 |
CDS | 335..1435 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGCAGCAG CAAGACACAG CACGCTCGAC TTCAAGCTCG GCGCCAAAGC TGATGGTGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen. |
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. |
Spermine synthase. |
Mouse models to investigate the function of spermine. |
Transcriptomic analysis of polyamine-related genes and polyamine levels in placenta, yolk sac and fetus during the second half of mouse pregnancy. |