Acmsd cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Summary

Gene Symbol	Acmsd
Entrez Gene ID	266645
Full Name	amino carboxymuconate semialdehyde decarboxylase
General protein information	Preferred Names amino carboxymuconate semialdehyde decarboxylase Names 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase picolinate carboxylase
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 1 Map Location: 1\|1 E3

mRNA and Protein(s)

mRNA	Protein	Name
NM_001033041.2	NP_001028213.1	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase

Pathways from BioSystems

Homologies

Homo sapiens (human)	ACMSD	NP_612199.2
Mus musculus (house mouse)	Acmsd	NP_001028213.1
Neurospora crassa	NCU06417	XP_957308.1
Pan troglodytes (chimpanzee)	ACMSD	XP_515804.1
	ACMSD	XP_001097996.1
Rattus norvegicus (Norway rat)	Acmsd	NP_599199.1
Caenorhabditis elegans (roundworm)	Y71D11A.3	NP_497336.3
Magnaporthe oryzae (rice blast fungus)	MGG_06488	XP_003717072.1
Canis lupus familiaris (dog)	ACMSD	XP_533332.3
Bos taurus (cattle)	ACMSD	NP_001069162.1
Gallus gallus (chicken)	ACMSD	XP_422133.2
Danio rerio (zebrafish)	acmsd	NP_001082963.1
Xenopus tropicalis (tropical clawed frog)	acmsd	XP_002941468.2

Gene Ontology
Bibliography

Related articles in PubMed

Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha.
Shin M, Kim I, Inoue Y, Kimura S, Gonzalez FJ
Molecular pharmacology70(4)1281-90(2006 Oct)

Identification and expression of a cDNA encoding human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD). A key enzyme for the tryptophan-niacine pathway and "quinolinate hypothesis".
Fukuoka S, Ishiguro K, Yanagihara K, Tanabe A, Egashira Y, Sanada H, Shibata K
The Journal of biological chemistry277(38)35162-7(2002 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Acmsd gene expression was found to be under the control of both hepatocyte nuclear factor 4alpha (HNF4alpha) and peroxisome proliferator-activated receptor alpha (PPARalpha).
Title: Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha.

The following Acmsd gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Acmsd cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu12419	NM_001033041.2 Latest version!	Mus musculus amino carboxymuconate semialdehyde decarboxylase (Acmsd), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Acmsd ( NM_001033041.2 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_001028213.1 Mus musculus amino carboxymuconate semialdehyde decarboxylase (Acmsd), mRNA.

Price & Availability↑

CloneID	OMu12419
Clone ID Related Accession (Same CDS sequence)	NM_001033041.2
Accession Version	NM_001033041.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1011bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Mus musculus(house mouse)
Product	2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK143962.1. On Apr 6, 2007 this sequence version replaced NM_001033041.1. ##Evidence-Data-START## Transcript exon combination :: AK143962.1, BC139281.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849385, SAMN00849386 [ECO:0000348] ##Evidence-Data-END##

ATGAAAATTG ACATCCACAC TCATATTCTA CCAAAGGAAT GGCCCGATCT AGAAAAGAGG 
TTTGGCTATG GAGGCTGGGT GCAGCTCCAA CAGCAAGGCA AGGGAGAAGC AAAGATGATA 
AAAGATGGGA AGCTCTTCAG AGTGATCCAA CAGAACTGCT GGGACCCAGA AGTTCGTATC 
AGAGAAATGA ACCAGAAAGG AGTGACAGTC CAAGCTCTTT CCACAGTTCC TGTCATGTTT 
AGCTACTGGG CCAAACCTAA GGATACTTTG GAGCTGTGCC AGTTTTTAAA CAATGACCTA 
GCTGCCACCG TTGCCAGATA CCCTCGAAGG TTTGTGGGTT TGGGGACGTT GCCTATGCAA 
GCCCCGGAGC TGGCCGTCGA GGAGATGGAG CGTTGTGTTA AGGCGCTAGG ATTTCCAGGA 
ATCCAGATTG GCTCCCACAT CAACACATGG GACCTGAATG ACCCGGAACT CTTCCCAATC 
TATGCTGCGG CCGAGAGGCT GAACTGTTCT CTGTTCGTGC ATCCCTGGGA TATGCAGATG 
GATGGACGAA TGGCCAAATA CTGGCTGCCT TGGCTCGTAG GAATGCCATC GGAGACCACC 
ATGGCCATTT GCTCCATGAT CATGGGTGGG GTGTTTGAGA AGTTTCCCAA ACTCAAAGTG 
TGCTTCGCAC ACGGAGGTGG TGCTTTCCCC TTCACCATAG GAAGAATTGC CCATGGATTC 
AACATGCGCC CAGATCTCTG TGCCCAGGAC AATCCGTCTG ACCCCAGAAA ATACCTTGGC 
TCCTTCTACA CAGACTCCCT GGTTCACGAT CCTCTGTCTC TCAAGCTATT GACAGATGTC 
ATAGGAAAGG ATAAAGTCAT GCTGGGAACT GATTACCCCT TTCCTCTGGG CGAGCAGGAG 
CCTGGGAAGC TGATAGAGTC CATGGCAGAG TTTGATGAAG AAACAAAGGA TAAACTTACA 
GCTGGCAATG CCTTGGCTTT TTTGGGTCTT GAGAGAAAAC TATTTGAATG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001028213.1
CDS	74..1084
Translation	MKIDIHTHILPKEWPDLEKRFGYGGWVQLQQQGKGEAKMIKDGKLFRVIQQNCWDPEVRIREMNQKGVTVQALSTVPVMFSYWAKPKDTLELCQFLNNDLAATVARYPRRFVGLGTLPMQAPELAVEEMERCVKALGFPGIQIGSHINTWDLNDPELFPIYAAAERLNCSLFVHPWDMQMDGRMAKYWLPWLVGMPSETTMAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTIGRIAHGFNMRPDLCAQDNPSDPRKYLGSFYTDSLVHDPLSLKLLTDVIGKDKVMLGTDYPFPLGEQEPGKLIESMAEFDEETKDKLTAGNALAFLGLERKLFE

Target ORF information:

RefSeq Version	NM_001033041.2
Organism	Mus musculus(house mouse)
Definition	Mus musculus amino carboxymuconate semialdehyde decarboxylase (Acmsd), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001033041.2

ORF Insert Sequence:

ATGAAAATTG ACATCCACAC TCATATTCTA CCAAAGGAAT GGCCCGATCT AGAAAAGAGG 
TTTGGCTATG GAGGCTGGGT GCAGCTCCAA CAGCAAGGCA AGGGAGAAGC AAAGATGATA 
AAAGATGGGA AGCTCTTCAG AGTGATCCAA CAGAACTGCT GGGACCCAGA AGTTCGTATC 
AGAGAAATGA ACCAGAAAGG AGTGACAGTC CAAGCTCTTT CCACAGTTCC TGTCATGTTT 
AGCTACTGGG CCAAACCTAA GGATACTTTG GAGCTGTGCC AGTTTTTAAA CAATGACCTA 
GCTGCCACCG TTGCCAGATA CCCTCGAAGG TTTGTGGGTT TGGGGACGTT GCCTATGCAA 
GCCCCGGAGC TGGCCGTCGA GGAGATGGAG CGTTGTGTTA AGGCGCTAGG ATTTCCAGGA 
ATCCAGATTG GCTCCCACAT CAACACATGG GACCTGAATG ACCCGGAACT CTTCCCAATC 
TATGCTGCGG CCGAGAGGCT GAACTGTTCT CTGTTCGTGC ATCCCTGGGA TATGCAGATG 
GATGGACGAA TGGCCAAATA CTGGCTGCCT TGGCTCGTAG GAATGCCATC GGAGACCACC 
ATGGCCATTT GCTCCATGAT CATGGGTGGG GTGTTTGAGA AGTTTCCCAA ACTCAAAGTG 
TGCTTCGCAC ACGGAGGTGG TGCTTTCCCC TTCACCATAG GAAGAATTGC CCATGGATTC 
AACATGCGCC CAGATCTCTG TGCCCAGGAC AATCCGTCTG ACCCCAGAAA ATACCTTGGC 
TCCTTCTACA CAGACTCCCT GGTTCACGAT CCTCTGTCTC TCAAGCTATT GACAGATGTC 
ATAGGAAAGG ATAAAGTCAT GCTGGGAACT GATTACCCCT TTCCTCTGGG CGAGCAGGAG 
CCTGGGAAGC TGATAGAGTC CATGGCAGAG TTTGATGAAG AAACAAAGGA TAAACTTACA 
GCTGGCAATG CCTTGGCTTT TTTGGGTCTT GAGAGAAAAC TATTTGAATG A