Gene Symbol | Noc2l |
Entrez Gene ID | 57741 |
Full Name | NOC2 like nucleolar associated transcriptional repressor |
Synonyms | AA410003,AF155546,NIR |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Noc2l cDNA ORF clone
gRNAs
Gene Symbol | Noc2l |
Entrez Gene ID | 57741 |
Full Name | NOC2 like nucleolar associated transcriptional repressor |
Synonyms | AA410003,AF155546,NIR |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_001369270.1 | NP_001356199.1 | nucleolar complex protein 2 homolog isoform 2 |
NM_021303.2 | NP_067278.2 | nucleolar complex protein 2 homolog isoform 1 |
XM_030253688.1 | XP_030109548.1 | nucleolar complex protein 2 homolog isoform X1 |
Homo sapiens (human) | NOC2L | NP_056473.2 |
Bos taurus (cattle) | NOC2L | NP_001029498.1 |
Eremothecium gossypii | AGOS_ADL277W | NP_983819.1 |
Neurospora crassa | NCU02066 | XP_964593.1 |
Arabidopsis thaliana (thale cress) | AT2G18220 | NP_179414.2 |
Xenopus tropicalis (tropical clawed frog) | noc2l | XP_002936424.2 |
NOC2L | XP_001089937.2 | |
Gallus gallus (chicken) | NOC2L | NP_001026047.1 |
Drosophila melanogaster (fruit fly) | CG9246 | NP_610095.1 |
Caenorhabditis elegans (roundworm) | pro-2 | NP_496224.1 |
Saccharomyces cerevisiae (baker's yeast) | NOC2 | NP_014849.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_08867 | XP_003713893.1 |
Danio rerio (zebrafish) | noc2l | NP_001003830.1 |
Oryza sativa (rice) | Os10g0495500 | NP_001064951.2 |
Pan troglodytes (chimpanzee) | LOC100608665 | XP_003318995.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010536 | XP_001237567.2 |
Schizosaccharomyces pombe (fission yeast) | SPAC1142.04 | NP_594268.1 |
Canis lupus familiaris (dog) | NOC2L | XP_546728.3 |
Mus musculus (house mouse) | Noc2l | NP_067278.2 |
Rattus norvegicus (Norway rat) | Noc2l | NP_001029069.1 |
Kluyveromyces lactis | KLLA0F01122g | XP_455130.1 |
Novel INHAT repressor (NIR) is required for early lymphocyte development.
Ma CA, Pusso A, Wu L, Zhao Y, Hoffmann V, Notarangelo LD, Fowlkes BJ, Jain A
Proceedings of the National Academy of Sciences of the United States of America111(38)13930-5(2014 Sep)
NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.
Hublitz P, Kunowska N, Mayer UP, M?ller JM, Heyne K, Yin N, Fritzsche C, Poli C, Miguet L, Schupp IW, van Grunsven LA, Potiers N, van Dorsselaer A, Metzger E, Roemer K, Sch?le R
Genes & development19(23)2912-24(2005 Dec)
Genomic analysis of mouse retinal development.
Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL
PLoS biology2(9)E247(2004 Sep)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
results show that NIR cooperate with p53 to impose checkpoint for the generation of mature B and T lymphocytes.
Title: Novel INHAT repressor (NIR) is required for early lymphocyte development.
Upon recruitment by p53, NIR represses transcription of both p53-dependent reporters and endogenous target genes
Title: NIR is a novel INHAT repressor that modulates the transcriptional activity of p53.
The following Noc2l gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Noc2l cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu84733 | |
Clone ID Related Accession (Same CDS sequence) | NM_001369270.1 | |
Accession Version | NM_001369270.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1782bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | nucleolar complex protein 2 homolog isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CAAA01066806.1 and CAAA01066805.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR7345562.676698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 5' end. |
1 | ATGGTGGAAA GGTGGAGGCA GGGCTCCAGG CACCACCTTA GTCCCAGGCT GTTCCATGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001356199.1 |
CDS | 659..2440 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGTGGAAA GGTGGAGGCA GGGCTCCAGG CACCACCTTA GTCCCAGGCT GTTCCATGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu88595 | |
Clone ID Related Accession (Same CDS sequence) | XM_030253688.1 | |
Accession Version | XM_030253688.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2334bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | nucleolar complex protein 2 homolog isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000070.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCGGGG CTCGCGGGAG GAAGTCGGAG GGCGCAAGGC ATTCTGGGCC CGGAAGTGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030109548.1 |
CDS | 849..3182 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGGCGGGG CTCGCGGGAG GAAGTCGGAG GGCGCAAGGC ATTCTGGGCC CGGAAGTGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu20822 | |
Clone ID Related Accession (Same CDS sequence) | NM_021303.2 | |
Accession Version | NM_021303.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2253bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-03 | |
Organism | Mus musculus(house mouse) | |
Product | nucleolar complex protein 2 homolog isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK133834.1 and AK157765.1. On Jan 31, 2007 this sequence version replaced NM_021303.1. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: AK157765.1, BC020013.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCTGCGT CTCGCGCTCC CCGCAGGCGC CTGGAGGACC TCAGTGTGGA CGAGTTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_067278.2 |
CDS | 36..2288 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGCGT CTCGCGCTCC CCGCAGGCGC CTGGAGGACC TCAGTGTGGA CGAGTTCCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Novel INHAT repressor (NIR) is required for early lymphocyte development. |
NIR is a novel INHAT repressor that modulates the transcriptional activity of p53. |
Genomic analysis of mouse retinal development. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |