Ppp2r1b cDNA ORF clone, Mus musculus(house mouse)
Gene Symbol | Ppp2r1b |
Entrez Gene ID | 73699 |
Full Name | protein phosphatase 2, regulatory subunit A, beta |
Synonyms | 2410091N08Rik,AI790395 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
XM_006510642.3 | XP_006510705.1 | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2 |
XM_006510641.4 | XP_006510704.2 | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 |
XM_006510642.4 | XP_006510705.2 | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2 |
NM_001286553.1 | NP_001273482.1 | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform c |
XM_006510641.3 | XP_006510704.1 | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 |
NM_001034085.2 | NP_001029257.1 | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform a |
NM_028614.3 | NP_082890.2 | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform b |

Canis lupus familiaris (dog) | PPP2R1B | XP_005619844.1 |
Mus musculus (house mouse) | Ppp2r1b | NP_001273482.1 |
LOC710387 | XP_002808132.1 | |
Rattus norvegicus (Norway rat) | Ppp2r1b | NP_001020589.1 |
Arabidopsis thaliana (thale cress) | PP2AA2 | NP_189208.1 |
Oryza sativa (rice) | Os09g0249700 | NP_001062674.1 |
Danio rerio (zebrafish) | ppp2r1b | NP_001005590.1 |
Arabidopsis thaliana (thale cress) | PP2AA3 | NP_172790.2 |
Homo sapiens (human) | PPP2R1B | NP_859050.1 |
Bos taurus (cattle) | PPP2R1B | XP_002693055.3 |
Xenopus tropicalis (tropical clawed frog) | pdgfb | NP_001006775.1 |
Pan troglodytes (chimpanzee) | PPP2R1B | XP_003313334.1 |

Related articles in PubMed
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting.
Biesemann C, Gr?nborg M, Luquet E, Wichert SP, Bernard V, Bungers SR, Cooper B, Varoqueaux F, Li L, Byrne JA, Urlaub H, Jahn O, Brose N, Herzog E
The EMBO journal33(2)157-70(2014 Jan)
The PP2A-A? gene is regulated by multiple transcriptional factors including Ets-1, SP1/SP3, and RXR?/?.
Liu J, Ji W, Sun S, Zhang L, Chen HG, Mao Y, Liu L, Zhang X, Gong L, Deng M, Chen L, Han WJ, Chen PC, Hu WF, Hu X, Woodward Z, Liu WB, Xiao YM, Liang SP, Liu Y, Liu SJ, Li DW
Current molecular medicine12(8)982-94(2012 Sep)
Gene expression analysis of the embryonic subplate.
Oeschger FM, Wang WZ, Lee S, Garc?a-Moreno F, Goffinet AM, Arbon?s ML, Rakic S, Moln?r Z
Cerebral cortex (New York, N.Y. : 1991)22(6)1343-59(2012 Jun)
Protein phosphatase 2A catalytic subunit ? (PP2Ac?) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway.
Chen W, Gu P, Jiang X, Ruan HB, Li C, Gao X
The American journal of pathology178(5)2333-43(2011 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Multiple transcription factors regulate the PP2A-Abeta gene.
Title: The PP2A-A? gene is regulated by multiple transcriptional factors including Ets-1, SP1/SP3, and RXR?/?.
PP-2A is less abundant than PP-1 in the mouse eye and appear to be highly regulated by various regulatory subunits; the genes encoding PP-1alpha/beta, PP-2Aalpha/beta, PP-2A-Aalpha/beta, and PP-2A-B alpha/beta/gamma are all differentially expressed.
Title: Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye.
The following Ppp2r1b gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Ppp2r1b cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu05858 | |
Clone ID Related Accession (Same CDS sequence) | NM_028614.3 | |
Accession Version | NM_028614.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1806bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123614.6, AK136106.1, AK077158.1, BC056218.1, AK010754.1, BM932667.1, CX566645.1 and BY687256.1. On Nov 8, 2013 this sequence version replaced NM_028614.2. Transcript Variant: This variant (2) uses an alternate 3' structure and contains a 3' terminal exon which extends past a splice site that is used in variant 3. It encodes isoform b, which has a shorter and distinct C-terminus, compared to isoform c. ##Evidence-Data-START## Transcript exon combination :: BC056218.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_082890.2 |
CDS | 62..1867 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu21896 | |
Clone ID Related Accession (Same CDS sequence) | NM_001034085.2 | |
Accession Version | NM_001034085.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1977bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123614.6 and AK161392.1. On Nov 8, 2013 this sequence version replaced NM_001034085.1. Transcript Variant: This variant (1) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 3. It encodes isoform a, which has a shorter and distinct C-terminus, compared to isoform c. ##Evidence-Data-START## Transcript exon combination :: AK161392.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164135 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001029257.1 |
CDS | 62..2038 |
Translation |

Target ORF information:
Target ORF information:
|
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ORF Insert Sequence:
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu42425 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510641.3 | |
Accession Version | XM_006510641.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2220bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006510641.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCCCT GCCCTTGTTT CTTTCGGCTG GGGAAAGGAT GCAGGGGTTC CATTGGTTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510704.1 |
CDS | 67..2286 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGAATCCCT GCCCTTGTTT CTTTCGGCTG GGGAAAGGAT GCAGGGGTTC CATTGGTTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu42426 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510642.3 | |
Accession Version | XM_006510642.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2196bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006510642.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAATCCCT GCCCTTGTTT CTTTCGGCTG GGGAAAGGAT GCAGGGGTTC CATTGGTTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510705.1 |
CDS | 67..2262 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGAATCCCT GCCCTTGTTT CTTTCGGCTG GGGAAAGGAT GCAGGGGTTC CATTGGTTTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu16978 | |
Clone ID Related Accession (Same CDS sequence) | NM_001286553.1 | |
Accession Version | NM_001286553.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2085bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC123614.6, AK136106.1, AK077158.1 and AK161392.1. Transcript Variant: This variant (3) encodes the longest isoform (c). ##Evidence-Data-START## Transcript exon combination :: AK077158.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849384, SAMN01164143 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001273482.1 |
CDS | 62..2146 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90286 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510641.4 | |
Accession Version | XM_006510641.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1926bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006510641.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510704.2 |
CDS | 83..2008 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu90287 | |
Clone ID Related Accession (Same CDS sequence) | XM_006510642.4 | |
Accession Version | XM_006510642.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1902bp) Protein sequence SNP |
|
Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006510642.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006510705.2 |
CDS | 82..1983 |
Translation |

Target ORF information:
Target ORF information:
|
![]() |

ORF Insert Sequence:
1 | ATGGCGGGCG CAGCAGGGCC AGGGTCCGGT CCGGGGGCAG CGGGTGGAGA TGGAGACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
High-throughput discovery of novel developmental phenotypes. |
![]() |
Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting. |
![]() |
The PP2A-A? gene is regulated by multiple transcriptional factors including Ets-1, SP1/SP3, and RXR?/?. |
![]() |
Gene expression analysis of the embryonic subplate. |
![]() |
Protein phosphatase 2A catalytic subunit ? (PP2Ac?) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway. |