CMTM6 cDNA ORF clone, Homo sapiens(human)

  • Gene

  • Clones

  • gRNAs

The following CMTM6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CMTM6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu24864 NM_017801.3
Latest version!
Homo sapiens CKLF like MARVEL transmembrane domain containing 6 (CMTM6), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
View Old Accession Versions >>
OHu24864 NM_017801.2 Homo sapiens CKLF like MARVEL transmembrane domain containing 6 (CMTM6), mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$49.50-$69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu24864
    Clone ID Related Accession (Same CDS sequence) NM_017801.3 , NM_017801.2
    Accession Version NM_017801.3 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 552bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-26
    Organism Homo sapiens(human)
    Product CKLF-like MARVEL transmembrane domain-containing protein 6
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC104306.2. On Nov 26, 2018 this sequence version replaced NM_017801.2. ##Evidence-Data-START## Transcript exon combination :: AF479261.1, SRR1660809.9855.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000205636.4/ ENSP00000205636.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGAGAACG GAGCGGTGTA CAGCCCCACT ACGGAGGAGG ACCCGGGCCC CGCCAGAGGC 
    CCCCGGAGCG GCCTCGCTGC CTACTTTTTC ATGGGCCGGC TCCCATTGCT CCGGCGCGTT
    CTCAAGGGCT TGCAGCTGTT GCTGTCTCTG CTGGCCTTCA TCTGTGAAGA AGTTGTATCA
    CAATGTACTT TATGTGGAGG ACTTTATTTT TTTGAGTTTG TAAGCTGCAG TGCCTTTCTT
    CTGAGTCTCC TTATACTGAT TGTGTATTGC ACTCCATTTT ATGAGAGAGT TGATACCACA
    AAAGTAAAAT CATCGGATTT TTATATTACT TTGGGAACAG GATGTGTGTT TTTGTTGGCA
    TCCATCATTT TTGTTTCCAC ACATGACAGG ACTTCAGCTG AGATTGCTGC AATTGTGTTT
    GGATTTATAG CAAGTTTTAT GTTCCTACTT GACTTTATCA CTATGCTGTA TGAAAAACGA
    CAGGAGTCCC AGCTGAGAAA ACCTGAAAAT ACCACTAGGG CTGAAGCCCT CACTGAGCCA
    CTTAATGCCT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_060271.1
    CDS108..659
    Translation

    Target ORF information:

    RefSeq Version NM_017801.3
    Organism Homo sapiens(human)
    Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 6 (CMTM6), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_017801.3

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGAGAACG GAGCGGTGTA CAGCCCCACT ACGGAGGAGG ACCCGGGCCC CGCCAGAGGC 
    CCCCGGAGCG GCCTCGCTGC CTACTTTTTC ATGGGCCGGC TCCCATTGCT CCGGCGCGTT
    CTCAAGGGCT TGCAGCTGTT GCTGTCTCTG CTGGCCTTCA TCTGTGAAGA AGTTGTATCA
    CAATGTACTT TATGTGGAGG ACTTTATTTT TTTGAGTTTG TAAGCTGCAG TGCCTTTCTT
    CTGAGTCTCC TTATACTGAT TGTGTATTGC ACTCCATTTT ATGAGAGAGT TGATACCACA
    AAAGTAAAAT CATCGGATTT TTATATTACT TTGGGAACAG GATGTGTGTT TTTGTTGGCA
    TCCATCATTT TTGTTTCCAC ACATGACAGG ACTTCAGCTG AGATTGCTGC AATTGTGTTT
    GGATTTATAG CAAGTTTTAT GTTCCTACTT GACTTTATCA CTATGCTGTA TGAAAAACGA
    CAGGAGTCCC AGCTGAGAAA ACCTGAAAAT ACCACTAGGG CTGAAGCCCT CACTGAGCCA
    CTTAATGCCT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu24864
    Clone ID Related Accession (Same CDS sequence) NM_017801.3 , NM_017801.2
    Accession Version NM_017801.2 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 552bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-09-30
    Organism Homo sapiens(human)
    Product CKLF-like MARVEL transmembrane domain-containing protein 6
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF479261.1. On Jun 20, 2003 this sequence version replaced NM_017801.1. ##Evidence-Data-START## Transcript exon combination :: AF479261.1, SRR1660809.9855.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGAGAACG GAGCGGTGTA CAGCCCCACT ACGGAGGAGG ACCCGGGCCC CGCCAGAGGC 
    CCCCGGAGCG GCCTCGCTGC CTACTTTTTC ATGGGCCGGC TCCCATTGCT CCGGCGCGTT
    CTCAAGGGCT TGCAGCTGTT GCTGTCTCTG CTGGCCTTCA TCTGTGAAGA AGTTGTATCA
    CAATGTACTT TATGTGGAGG ACTTTATTTT TTTGAGTTTG TAAGCTGCAG TGCCTTTCTT
    CTGAGTCTCC TTATACTGAT TGTGTATTGC ACTCCATTTT ATGAGAGAGT TGATACCACA
    AAAGTAAAAT CATCGGATTT TTATATTACT TTGGGAACAG GATGTGTGTT TTTGTTGGCA
    TCCATCATTT TTGTTTCCAC ACATGACAGG ACTTCAGCTG AGATTGCTGC AATTGTGTTT
    GGATTTATAG CAAGTTTTAT GTTCCTACTT GACTTTATCA CTATGCTGTA TGAAAAACGA
    CAGGAGTCCC AGCTGAGAAA ACCTGAAAAT ACCACTAGGG CTGAAGCCCT CACTGAGCCA
    CTTAATGCCT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_060271.1
    CDS167..718
    Translation

    Target ORF information:

    RefSeq Version NM_017801.2
    Organism Homo sapiens(human)
    Definition Homo sapiens CKLF like MARVEL transmembrane domain containing 6 (CMTM6), mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_017801.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGAGAACG GAGCGGTGTA CAGCCCCACT ACGGAGGAGG ACCCGGGCCC CGCCAGAGGC 
    CCCCGGAGCG GCCTCGCTGC CTACTTTTTC ATGGGCCGGC TCCCATTGCT CCGGCGCGTT
    CTCAAGGGCT TGCAGCTGTT GCTGTCTCTG CTGGCCTTCA TCTGTGAAGA AGTTGTATCA
    CAATGTACTT TATGTGGAGG ACTTTATTTT TTTGAGTTTG TAAGCTGCAG TGCCTTTCTT
    CTGAGTCTCC TTATACTGAT TGTGTATTGC ACTCCATTTT ATGAGAGAGT TGATACCACA
    AAAGTAAAAT CATCGGATTT TTATATTACT TTGGGAACAG GATGTGTGTT TTTGTTGGCA
    TCCATCATTT TTGTTTCCAC ACATGACAGG ACTTCAGCTG AGATTGCTGC AATTGTGTTT
    GGATTTATAG CAAGTTTTAT GTTCCTACTT GACTTTATCA CTATGCTGTA TGAAAAACGA
    CAGGAGTCCC AGCTGAGAAA ACCTGAAAAT ACCACTAGGG CTGAAGCCCT CACTGAGCCA
    CTTAATGCCT AA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.
    Nature549(7670)101-105(2017 09)
    Burr ML,Sparbier CE,Chan YC,Williamson JC,Woods K,Beavis PA,Lam EYN,Henderson MA,Bell CC,Stolzenburg S,Gilan O,Bloor S,Noori T,Morgens DW,Bassik MC,Neeson PJ,Behren A,Darcy PK,Dawson SJ,Voskoboinik I,Trapani JA,Cebon J,Lehner PJ,Dawson MA


    Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.
    Nature549(7670)106-110(2017 09)
    Mezzadra R,Sun C,Jae LT,Gomez-Eerland R,de Vries E,Wu W,Logtenberg MEW,Slagter M,Rozeman EA,Hofland I,Broeks A,Horlings HM,Wessels LFA,Blank CU,Xiao Y,Heck AJR,Borst J,Brummelkamp TR,Schumacher TNM


    Discovery and refinement of loci associated with lipid levels.
    Nature genetics45(11)1274-1283(2013 Nov)
    Willer CJ,Schmidt EM,Sengupta S,Peloso GM,Gustafsson S,Kanoni S,Ganna A,Chen J,Buchkovich ML,Mora S,Beckmann JS,Bragg-Gresham JL,Chang HY,Demirkan A,Den Hertog HM,Do R,Donnelly LA,Ehret GB,Esko T,Feitosa MF,Ferreira T,Fischer K,Fontanillas P,Fraser RM,Freitag DF,Gurdasani D,Heikkil? K,Hypp?nen E,Isaacs A,Jackson AU,Johansson ?,Johnson T,Kaakinen M,Kettunen J,Kleber ME,Li X,Luan J,Lyytik?inen LP,Magnusson PKE,Mangino M,Mihailov E,Montasser ME,M?ller-Nurasyid M,Nolte IM,O'Connell JR,Palmer CD,Perola M,Petersen AK,Sanna S,Saxena R,Service SK,Shah S,Shungin D,Sidore C,Song C,Strawbridge RJ,Surakka I,Tanaka T,Teslovich TM,Thorleifsson G,Van den Herik EG,Voight BF,Volcik KA,Waite LL,Wong A,Wu Y,Zhang W,Absher D,Asiki G,Barroso I,Been LF,Bolton JL,Bonnycastle LL,Brambilla P,Burnett MS,Cesana G,Dimitriou M,Doney ASF,D?ring A,Elliott P,Epstein SE,Ingi Eyjolfsson G,Gigante B,Goodarzi MO,Grallert H,Gravito ML,Groves CJ,Hallmans G,Hartikainen AL,Hayward C,Hernandez D,Hicks AA,Holm H,Hung YJ,Illig T,Jones MR,Kaleebu P,Kastelein JJP,Khaw KT,Kim E,Klopp N,Komulainen P,Kumari M,Langenberg C,Lehtim?ki T,Lin SY,Lindstr?m J,Loos RJF,Mach F,McArdle WL,Meisinger C,Mitchell BD,M?ller G,Nagaraja R,Narisu N,Nieminen TVM,Nsubuga RN,Olafsson I,Ong KK,Palotie A,Papamarkou T,Pomilla C,Pouta A,Rader DJ,Reilly MP,Ridker PM,Rivadeneira F,Rudan I,Ruokonen A,Samani N,Scharnagl H,Seeley J,Silander K,Stan??kov? A,Stirrups K,Swift AJ,Tiret L,Uitterlinden AG,van Pelt LJ,Vedantam S,Wainwright N,Wijmenga C,Wild SH,Willemsen G,Wilsgaard T,Wilson JF,Young EH,Zhao JH,Adair LS,Arveiler D,Assimes TL,Bandinelli S,Bennett F,Bochud M,Boehm BO,Boomsma DI,Borecki IB,Bornstein SR,Bovet P,Burnier M,Campbell H,Chakravarti A,Chambers JC,Chen YI,Collins FS,Cooper RS,Danesh J,Dedoussis G,de Faire U,Feranil AB,Ferri?res J,Ferrucci L,Freimer NB,Gieger C,Groop LC,Gudnason V,Gyllensten U,Hamsten A,Harris TB,Hingorani A,Hirschhorn JN,Hofman A,Hovingh GK,Hsiung CA,Humphries SE,Hunt SC,Hveem K,Iribarren C,J?rvelin MR,Jula A,K?h?nen M,Kaprio J,Kes?niemi A,Kivimaki M,Kooner JS,Koudstaal PJ,Krauss RM,Kuh D,Kuusisto J,Kyvik KO,Laakso M,Lakka TA,Lind L,Lindgren CM,Martin NG,M?rz W,McCarthy MI,McKenzie CA,Meneton P,Metspalu A,Moilanen L,Morris AD,Munroe PB,Nj?lstad I,Pedersen NL,Power C,Pramstaller PP,Price JF,Psaty BM,Quertermous T,Rauramaa R,Saleheen D,Salomaa V,Sanghera DK,Saramies J,Schwarz PEH,Sheu WH,Shuldiner AR,Siegbahn A,Spector TD,Stefansson K,Strachan DP,Tayo BO,Tremoli E,Tuomilehto J,Uusitupa M,van Duijn CM,Vollenweider P,Wallentin L,Wareham NJ,Whitfield JB,Wolffenbuttel BHR,Ordovas JM,Boerwinkle E,Palmer CNA,Thorsteinsdottir U,Chasman DI,Rotter JI,Franks PW,Ripatti S,Cupples LA,Sandhu MS,Rich SS,Boehnke M,Deloukas P,Kathiresan S,Mohlke KL,Ingelsson E,Abecasis GR,


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