C6 cDNA ORF clone, Rattus norvegicus(Norway rat)

Gene
Clones
gRNAs

Summary

Gene Symbol	C6
Entrez Gene ID	24237
Full Name	complement C6
General protein information	Preferred Names complement C6 Names complement component C6 complement component 6
Gene Type	protein-coding
Organism	Rattus norvegicus(Norway rat)
Genome	Chromosome: 2 Map Location: 2q16
Summary	component of the complement cascade for immune response; may be a component of the membrane attack complex [RGD, Feb 2006].

mRNA and Protein(s)

mRNA	Protein	Name
NM_176074.3	NP_788263.1	complement component C6 precursor
XM_008760747.2	XP_008758969.1	complement component C6 isoform X1
XM_008760750.2	XP_008758972.1	complement component C6 isoform X2
XM_008760749.2	XP_008758971.1	complement component C6 isoform X1

Pathways from BioSystems

Homologies

Xenopus tropicalis (tropical clawed frog)	LOC100485342	XP_002940164.1
Homo sapiens (human)	C6	NP_000056.2
Gallus gallus (chicken)	C6	NP_001138321.1
	C6	XP_001087355.1
Canis lupus familiaris (dog)	C6	XP_536488.2
Xenopus tropicalis (tropical clawed frog)	c6.2	NP_001006864.1
Bos taurus (cattle)	C6	NP_001039444.1
Mus musculus (house mouse)	C6	NP_057913.2
Rattus norvegicus (Norway rat)	C6	NP_788263.1
Pan troglodytes (chimpanzee)	C6	NP_001009015.1
Danio rerio (zebrafish)	c6	NP_956932.1

Gene Ontology
Bibliography

Related articles in PubMed

C6 deficiency does not alter intrinsic regeneration speed after peripheral nerve crush injury.
Sta M, Cappaert NL, Ramekers D, Ramaglia V, Wadman WJ, Baas F
Neuroscience research8726-32(2014 Oct)

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.
Hadders MA, Bubeck D, Roversi P, Hakobyan S, Forneris F, Morgan BP, Pangburn MK, Llorca O, Lea SM, Gros P
Cell reports1(3)200-7(2012 Mar)

Complement protein 6 deficiency in PVG/c rats does not lead to neuroprotection against seizure induced cell death.
Holtman L, van Vliet EA, Baas F, Aronica E, Gorter JA
Neuroscience188109-16(2011 Aug)

Complement inhibition accelerates regeneration in a model of peripheral nerve injury.
Ramaglia V, Tannemaat MR, de Kok M, Wolterman R, Vigar MA, King RH, Morgan BP, Baas F
Molecular immunology47(2-3)302-9(2009 Dec)

Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.
Ruseva MM, Hughes TR, Donev RM, Sivasankar B, Pickering MC, Wu X, Harris CL, Morgan BP
Molecular immunology46(5)803-11(2009 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Findings suggest that C6 deficiency by itself does not alter the regrowth capacity of the peripheral nerve after crush injury.
Title: C6 deficiency does not alter intrinsic regeneration speed after peripheral nerve crush injury.

C6 deficiency did not lead to neuroprotection after status epilepticus
Title: Complement protein 6 deficiency in PVG/c rats does not lead to neuroprotection against seizure induced cell death.

Pathology showed improved nerve regeneration in tibials of C6 deficient animals compared to wildtypes.
Title: Complement inhibition accelerates regeneration in a model of peripheral nerve injury.

essential in the mechanism of hepatic ischemia/reperfusion injury
Title: The membrane attack complex (C5b-9) in liver cold ischemia and reperfusion injury.

The present study thus defines a novel role for ASK1 as a mediator of C5b-9-dependent cell injury.
Title: Role of apoptosis signal-regulating kinase 1 in complement-mediated glomerular epithelial cell injury.

The following C6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the C6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
ORa03981	NM_176074.3 Latest version!	Rattus norvegicus complement C6 (C6), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
ORa42869	XM_008760747.2 Latest version!	Rattus norvegicus complement component 6 (C6), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa42869	XM_008760749.2 Latest version!	Rattus norvegicus complement component 6 (C6), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
ORa42870	XM_008760750.2 Latest version!	Rattus norvegicus complement component 6 (C6), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

C6 ( NM_176074.3 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> NP_788263.1 Rattus norvegicus complement C6 (C6), mRNA.

Price & Availability↑

CloneID	ORa03981
Clone ID Related Accession (Same CDS sequence)	NM_176074.3
Accession Version	NM_176074.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Rattus norvegicus(Norway rat)
Product	complement component C6 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY230250.1. On Aug 31, 2012 this sequence version replaced NM_176074.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY230250.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2689598, SAMEA2689599 [ECO:0000348] ##Evidence-Data-END##

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGATCA TACTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAATC GTAGTGAACG ATTACTATCG GGATAACTCA 
TGCGATCAGC TCTGTACCAA GCAGGAGACC AGACAGTGCA ACGTGGAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGAACATGG TCAGACTGTG ACCCTTGTAT TAGAAAACAG 
GTTAAAGTTA GATCTGTTCT GCGCCCAAGT CAGTTTGGGG GACAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCATCT GAGCTCTGCA AAATTGAAGA GACTGATTGC 
AAGAATAAAT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAAA ATGCAATGGA 
GAAAATGACT GTGGAGACAA TTCAGACGAA AGGAACTGTG GGAGGACAAA GCCAGTATGC 
TCACGGACAT ACACTCCTAT CCCCAGTGTG CAGCTGATGG GCGCTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA TGTCCCTGAT AACTCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TCTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC GGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCGATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA AGCTGTGGGA 
TACCAGTACT TCAGATGCTT ACCAGACAGA ACCTGGAGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACTTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_788263.1
CDS	3..2807
Translation	MTRHLTLCFILLIILIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQIVVNDYYRDNSCDQLCTKQETRQCNVETCPINCVLGDYGTWSDCDPCIRKQVKVRSVLRPSQFGGQPCTEPLVTFQPCVPSELCKIEETDCKNKFLCDSGRCIPSKLKCNGENDCGDNSDERNCGRTKPVCSRTYTPIPSVQLMGAGFHFLAGEPRGDVPDNSFTGGICKSVRSSRTSNPHRVPANLENVNFEVQTIEDDLKTDFYKDLATIGKNKNEDRSLSGEKKDSFYVPIFYSSKKSENFQRNSGFKNAIEASHKKDSSFVRIHKVIKVLNFTMKTTDLQLSDVFLKALIHLPLEYNFALYSRIFDDFGTHYFTSGSLGGKYDLLYQFSRQELQNSGLTEEETRNCVRYETKKRFLFFTKTYKEDRCTTNRLSEKYKGSFLQGSEKSISLVQGGRSQQAAALAWEKGSSGPEANVFSEWLESVKENPAVVDYELAPIIDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCEKRSPDYKSNAVDGNWGCWSSWSACNAAYRRSRSRECNNPEPQRGGQRCEGKHWQEEDCTFSIMEKVGQPCISDDEEIKEVDLAEPEADSGCPQPPLPENAFVWNEKKLYSVGEEVEISCLTGFKAVGYQYFRCLPDRTWRQGDVECQRTECLKPVVQDVLTISPFQSVYKIGESIELTCPRGFVVAGPSRYTCKGDSWTPPIPNSLSCEKDILTKSKGLCQPGQKQSGSECVCMSPEEDCSSYSEDLCIFDEGSSQYFTSSACKFLAEKCLNSNQFHFVHAGSCQEGPQLEWGLERLKLAMKSTKRVPCGYDTCYDWEKCSAHTSNCVCLLPPQCPKDENQLHCVKMGSSMRGKTVNICTLGAVRCANRKVEILNPGRCLD

Target ORF information:

RefSeq Version	NM_176074.3
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus complement C6 (C6), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_176074.3

ORF Insert Sequence:

ATGACCAGAC ATCTCACCTT GTGTTTCATT TTGCTGATCA TACTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAATC GTAGTGAACG ATTACTATCG GGATAACTCA 
TGCGATCAGC TCTGTACCAA GCAGGAGACC AGACAGTGCA ACGTGGAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGAACATGG TCAGACTGTG ACCCTTGTAT TAGAAAACAG 
GTTAAAGTTA GATCTGTTCT GCGCCCAAGT CAGTTTGGGG GACAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCATCT GAGCTCTGCA AAATTGAAGA GACTGATTGC 
AAGAATAAAT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAAA ATGCAATGGA 
GAAAATGACT GTGGAGACAA TTCAGACGAA AGGAACTGTG GGAGGACAAA GCCAGTATGC 
TCACGGACAT ACACTCCTAT CCCCAGTGTG CAGCTGATGG GCGCTGGGTT TCATTTTCTG 
GCAGGAGAGC CCAGAGGAGA TGTCCCTGAT AACTCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TCTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC GGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCGATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA AGCTGTGGGA 
TACCAGTACT TCAGATGCTT ACCAGACAGA ACCTGGAGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACTTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C6 ( XM_008760747.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758969.1 Rattus norvegicus complement component 6 (C6), transcript variant X1, mRNA.

Price & Availability↑

CloneID	ORa42869
Clone ID Related Accession (Same CDS sequence)	XM_008760747.2 , XM_008760749.2
Accession Version	XM_008760747.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2265bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	complement component C6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760747.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACGG ACATACACTC CTATCCCCAG TGTGCAGCTG ATGGGCGCTG GGTTTCATTT 
CTGGCAGGAG AGCCCAGAGG AGATGCCTTG AAATCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TTTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC AGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCAATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA GAGCCTGTGG 
ATACCAGTAC TCAGATGCTT ACCAGCAGAA CCTGGAGGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACCTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758969.1
CDS	724..2988
Translation	MLTDIHSYPQCAADGRWVSFLAGEPRGDALKSFTGGICKSVRSSRTSNPHRVPANLENVNFEVQTIEDDLKTDFYKDLATIGKNKNEDRSLSGEKKDSFYVPIFYSSKKSENFQRNSGFKNAIEASHKKDSSFVRIHKVIKVLNFTMKTTDLQLSDVFLKALIHLPLEYNFALYSRIFDDFGTHYFTSGSLGGKYDLLYQFSRQELQNSGLTEEETRNCVRYETKKRFLFFTKTYKEDRCTTNRLSEKYKGSFLQGSEKSISLVQGGRSQQAAALAWEKGSSGPEANVFSEWLESVKENPAVVDYELAPIIDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCEKRSPDYKSNAVDGNWGCWSSWSACNAAYRRSRSRECNNPEPQRGGQRCEGKHWQEEDCTFSIMEKVGQPCISDDEEIKEVDLAEPEADSGCPQPPLPENAFVWNEKKLYSVGEEVEISCLTGFKSLWIPVLRCLPAEPGGQGDVECQRTECLKPVVQDVLTISPFQSVYKIGESIELTCPRGFVVAGPSRYTCKGDSWTPPIPNSLSCEKDILTKSKGLCQPGQKQSGSECVCMSPEEDCSSYSEDLCIFDEGSSQYFTSSACKFLAEKCLNSNQFHFVHAGSCQEGPQLEWGLERLKLAMKSTKRVPCGYDTCYDWEKCSAHTSNCVCLLPPQCPKDENQLHCVKMGSSMRGKTVNICTLGAVRCANRKVEILNPGRCLD

Target ORF information:

RefSeq Version	XM_008760747.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus complement component 6 (C6), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760747.2

ORF Insert Sequence:

ATGCTCACGG ACATACACTC CTATCCCCAG TGTGCAGCTG ATGGGCGCTG GGTTTCATTT 
CTGGCAGGAG AGCCCAGAGG AGATGCCTTG AAATCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TTTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC AGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCAATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA GAGCCTGTGG 
ATACCAGTAC TCAGATGCTT ACCAGCAGAA CCTGGAGGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACCTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C6 ( XM_008760749.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758971.1 Rattus norvegicus complement component 6 (C6), transcript variant X2, mRNA.

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CloneID	ORa42869
Clone ID Related Accession (Same CDS sequence)	XM_008760747.2 , XM_008760749.2
Accession Version	XM_008760749.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2265bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	complement component C6 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760749.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCACGG ACATACACTC CTATCCCCAG TGTGCAGCTG ATGGGCGCTG GGTTTCATTT 
CTGGCAGGAG AGCCCAGAGG AGATGCCTTG AAATCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TTTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC AGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCAATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA GAGCCTGTGG 
ATACCAGTAC TCAGATGCTT ACCAGCAGAA CCTGGAGGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACCTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758971.1
CDS	709..2973
Translation	MLTDIHSYPQCAADGRWVSFLAGEPRGDALKSFTGGICKSVRSSRTSNPHRVPANLENVNFEVQTIEDDLKTDFYKDLATIGKNKNEDRSLSGEKKDSFYVPIFYSSKKSENFQRNSGFKNAIEASHKKDSSFVRIHKVIKVLNFTMKTTDLQLSDVFLKALIHLPLEYNFALYSRIFDDFGTHYFTSGSLGGKYDLLYQFSRQELQNSGLTEEETRNCVRYETKKRFLFFTKTYKEDRCTTNRLSEKYKGSFLQGSEKSISLVQGGRSQQAAALAWEKGSSGPEANVFSEWLESVKENPAVVDYELAPIIDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCEKRSPDYKSNAVDGNWGCWSSWSACNAAYRRSRSRECNNPEPQRGGQRCEGKHWQEEDCTFSIMEKVGQPCISDDEEIKEVDLAEPEADSGCPQPPLPENAFVWNEKKLYSVGEEVEISCLTGFKSLWIPVLRCLPAEPGGQGDVECQRTECLKPVVQDVLTISPFQSVYKIGESIELTCPRGFVVAGPSRYTCKGDSWTPPIPNSLSCEKDILTKSKGLCQPGQKQSGSECVCMSPEEDCSSYSEDLCIFDEGSSQYFTSSACKFLAEKCLNSNQFHFVHAGSCQEGPQLEWGLERLKLAMKSTKRVPCGYDTCYDWEKCSAHTSNCVCLLPPQCPKDENQLHCVKMGSSMRGKTVNICTLGAVRCANRKVEILNPGRCLD

Target ORF information:

RefSeq Version	XM_008760749.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus complement component 6 (C6), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760749.2

ORF Insert Sequence:

ATGCTCACGG ACATACACTC CTATCCCCAG TGTGCAGCTG ATGGGCGCTG GGTTTCATTT 
CTGGCAGGAG AGCCCAGAGG AGATGCCTTG AAATCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TTTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC AGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCAATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA GAGCCTGTGG 
ATACCAGTAC TCAGATGCTT ACCAGCAGAA CCTGGAGGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACCTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

C6 ( XM_008760750.2 ) cDNA ORF clone, Rattus norvegicus(Norway rat) -> XP_008758972.1 Rattus norvegicus complement component 6 (C6), transcript variant X3, mRNA.

Price & Availability↑

CloneID	ORa42870
Clone ID Related Accession (Same CDS sequence)	XM_008760750.2
Accession Version	XM_008760750.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2805bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-07-25
Organism	Rattus norvegicus(Norway rat)
Product	complement component C6 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005101.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760750.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCAGAC ATCTCCCCTT GTGTTTCATT TTGCTGATCA TACTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAATC GTAGTGAACG ATTACTATCG GGATAACTCA 
TGCGATCAGC TCTGTACCAA GCAGGAGACC AGACAGTGCA ACGTGGAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGAACATGG TCAGACTGTG ACCCTTGTAT TAGAAAACAG 
GTTAAAGTTA GATCTGTTCT GCGCCCAAGT CAGTTTGGGG GACAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCATCT GAGCTCTGCA AAATTGAAGA GACTGATTGC 
AAGAATAAAT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAAAATGACT GTGGAGACAA TTCAGACGAA AGGAACTGTG GGAGGACAAA GCCAGTATGC 
TCACGGACAT ACACTCCTAT CCCCAGTGTG CAGCTGATGG GCGCTGGGTA TGTTTCATTT 
CTGGCAGGAG AGCCCAGAGG AGATGCCTTG AAATCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TTTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC AGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCAATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA GAGCCTGTGG 
ATACCAGTAC TCAGATGCTT ACCAGCAGAA CCTGGAGGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACCTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_008758972.1
CDS	188..2992
Translation	MTRHLPLCFILLIILIDKSEACFCDHYPWTHWSSCSKSCNSGTQSRQRQIVVNDYYRDNSCDQLCTKQETRQCNVETCPINCVLGDYGTWSDCDPCIRKQVKVRSVLRPSQFGGQPCTEPLVTFQPCVPSELCKIEETDCKNKFLCDSGRCIPSKLECNGENDCGDNSDERNCGRTKPVCSRTYTPIPSVQLMGAGYVSFLAGEPRGDALKSFTGGICKSVRSSRTSNPHRVPANLENVNFEVQTIEDDLKTDFYKDLATIGKNKNEDRSLSGEKKDSFYVPIFYSSKKSENFQRNSGFKNAIEASHKKDSSFVRIHKVIKVLNFTMKTTDLQLSDVFLKALIHLPLEYNFALYSRIFDDFGTHYFTSGSLGGKYDLLYQFSRQELQNSGLTEEETRNCVRYETKKRFLFFTKTYKEDRCTTNRLSEKYKGSFLQGSEKSISLVQGGRSQQAAALAWEKGSSGPEANVFSEWLESVKENPAVVDYELAPIIDLVRNIPCAVTKRNNLRKALQEYAAKFDPCQCAPCPNNGRPRLSGTECLCVCQSGTYGENCEKRSPDYKSNAVDGNWGCWSSWSACNAAYRRSRSRECNNPEPQRGGQRCEGKHWQEEDCTFSIMEKVGQPCISDDEEIKEVDLAEPEADSGCPQPPLPENAFVWNEKKLYSVGEEVEISCLTGFKSLWIPVLRCLPAEPGGQGDVECQRTECLKPVVQDVLTISPFQSVYKIGESIELTCPRGFVVAGPSRYTCKGDSWTPPIPNSLSCEKDILTKSKGLCQPGQKQSGSECVCMSPEEDCSSYSEDLCIFDEGSSQYFTSSACKFLAEKCLNSNQFHFVHAGSCQEGPQLEWGLERLKLAMKSTKRVPCGYDTCYDWEKCSAHTSNCVCLLPPQCPKDENQLHCVKMGSSMRGKTVNICTLGAVRCANRKVEILNPGRCLD

Target ORF information:

RefSeq Version	XM_008760750.2
Organism	Rattus norvegicus(Norway rat)
Definition	Rattus norvegicus complement component 6 (C6), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_008760750.2

ORF Insert Sequence:

ATGACCAGAC ATCTCCCCTT GTGTTTCATT TTGCTGATCA TACTGATTGA CAAGAGTGAA 
GCCTGTTTCT GTGACCACTA CCCATGGACT CACTGGTCCA GCTGTTCTAA GTCCTGCAAT 
TCTGGAACCC AGAGCAGACA GAGACAAATC GTAGTGAACG ATTACTATCG GGATAACTCA 
TGCGATCAGC TCTGTACCAA GCAGGAGACC AGACAGTGCA ACGTGGAGAC ATGTCCCATC 
AACTGTGTCC TAGGAGACTA TGGAACATGG TCAGACTGTG ACCCTTGTAT TAGAAAACAG 
GTTAAAGTTA GATCTGTTCT GCGCCCAAGT CAGTTTGGGG GACAACCATG CACAGAGCCC 
CTGGTGACCT TTCAACCATG TGTCCCATCT GAGCTCTGCA AAATTGAAGA GACTGATTGC 
AAGAATAAAT TCCTCTGTGA CAGTGGGCGC TGTATTCCCA GCAAGTTAGA ATGCAATGGA 
GAAAATGACT GTGGAGACAA TTCAGACGAA AGGAACTGTG GGAGGACAAA GCCAGTATGC 
TCACGGACAT ACACTCCTAT CCCCAGTGTG CAGCTGATGG GCGCTGGGTA TGTTTCATTT 
CTGGCAGGAG AGCCCAGAGG AGATGCCTTG AAATCCTTCA CTGGAGGAAT ATGTAAATCC 
GTCAGGAGCA GCCGAACGAG TAATCCACAC CGAGTTCCAG CCAATCTGGA AAATGTCAAC 
TTTGAGGTAC AAACTATAGA AGATGACTTG AAAACAGATT TCTACAAGGA TTTAGCCACT 
ATTGGAAAAA ATAAAAATGA AGACCGTTCA TTGTCTGGTG AGAAGAAAGA CTCTTTCTAC 
GTACCAATTT TTTATTCCTC AAAGAAAAGT GAAAATTTCC AACGTAACTC AGGCTTCAAA 
AACGCCATTG AAGCCTCCCA CAAGAAGGAT TCGAGCTTTG TTAGGATCCA TAAAGTGATA 
AAAGTCTTAA ACTTCACAAT GAAAACGACA GACCTGCAGC TTTCAGACGT CTTCCTAAAA 
GCCCTCATCC ACCTGCCTTT AGAATACAAC TTTGCTTTGT ACAGCCGGAT ATTTGATGAC 
TTTGGGACCC ACTATTTCAC CTCAGGCTCC CTTGGGGGCA AGTATGACCT TCTCTACCAA 
TTCAGCCGCC AGGAGCTACA GAACTCAGGT TTAACAGAAG AAGAAACTCG AAACTGTGTC 
CGGTATGAAA CAAAGAAACG TTTCTTATTT TTTACGAAAA CATACAAGGA AGACCGGTGT 
ACCACAAATA GGCTGTCTGA AAAGTACAAA GGTTCCTTTT TACAGGGATC AGAGAAATCT 
ATATCCCTGG TCCAGGGCGG GAGGAGTCAG CAGGCAGCAG CCTTGGCTTG GGAGAAGGGC 
AGCTCTGGTC CAGAGGCGAA TGTCTTCTCT GAGTGGTTAG AGTCGGTGAA GGAAAACCCT 
GCTGTGGTTG ATTATGAGCT TGCTCCAATC ATCGACTTGG TCAGAAACAT CCCATGTGCA 
GTGACAAAAC GGAACAACCT CAGGAAAGCC CTTCAAGAAT ATGCAGCCAA GTTTGACCCT 
TGCCAATGTG CTCCATGTCC TAATAATGGC CGCCCCAGGC TCTCAGGCAC AGAATGTTTG 
TGTGTGTGCC AGAGTGGTAC CTACGGTGAG AACTGTGAAA AACGGTCCCC AGATTATAAA 
TCGAATGCAG TGGATGGGAA CTGGGGCTGC TGGTCTTCCT GGAGCGCATG CAATGCTGCT 
TATAGGAGGT CAAGGAGCCG GGAGTGTAAT AACCCTGAGC CACAGCGAGG AGGGCAGCGC 
TGTGAGGGCA AGCATTGGCA AGAAGAAGAC TGTACATTCT CAATAATGGA AAAAGTTGGA 
CAACCGTGCA TCAGTGATGA TGAAGAAATA AAAGAAGTAG ACCTTGCTGA GCCAGAAGCA 
GATTCAGGGT GTCCTCAGCC ACCTCTCCCA GAAAATGCAT TTGTCTGGAA TGAAAAGAAA 
CTGTACTCAG TCGGGGAGGA AGTTGAAATT TCATGTCTCA CTGGATTCAA GAGCCTGTGG 
ATACCAGTAC TCAGATGCTT ACCAGCAGAA CCTGGAGGGC AAGGGGATGT CGAATGCCAA 
CGGACCGAGT GCCTCAAACC AGTCGTTCAG GATGTCCTGA CCATCTCCCC ATTTCAGAGT 
GTGTACAAGA TTGGGGAATC CATTGAGCTG ACCTGTCCCA GAGGCTTTGT TGTTGCTGGC 
CCATCGAGGT ATACATGCAA GGGAGACTCC TGGACACCTC CCATTCCAAA TTCACTGAGC 
TGTGAAAAAG ATATTCTGAC AAAGTCAAAG GGCCTTTGTC AACCAGGACA AAAGCAATCA 
GGATCCGAGT GTGTTTGTAT GTCCCCAGAA GAAGACTGTA GCAGTTATTC GGAAGATCTC 
TGTATATTTG ATGAGGGATC CAGTCAGTAC TTCACTTCAT CTGCTTGCAA ATTTTTGGCT 
GAAAAATGTT TAAACAGCAA CCAGTTCCAC TTTGTCCATG CTGGTTCCTG CCAAGAAGGC 
CCACAGTTAG AATGGGGTCT TGAGAGGCTA AAACTCGCAA TGAAGAGCAC AAAGAGAGTG 
CCCTGTGGAT ATGATACCTG CTATGACTGG GAAAAATGTT CAGCCCACAC CTCCAACTGT 
GTCTGCCTAT TGCCCCCACA ATGCCCCAAG GATGAAAACC AACTCCACTG TGTCAAAATG 
GGATCATCAA TGCGTGGGAA AACAGTAAAC ATCTGTACAC TGGGAGCCGT GAGGTGTGCA 
AACAGGAAGG TGGAAATACT GAATCCTGGG AGGTGCTTGG ATTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

C6 deficiency does not alter intrinsic regeneration speed after peripheral nerve crush injury.
Neuroscience research8726-32(2014 Oct)
Sta M,Cappaert NL,Ramekers D,Ramaglia V,Wadman WJ,Baas F

Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9.
Cell reports1(3)200-7(2012 Mar)
Hadders MA,Bubeck D,Roversi P,Hakobyan S,Forneris F,Morgan BP,Pangburn MK,Llorca O,Lea SM,Gros P

Complement protein 6 deficiency in PVG/c rats does not lead to neuroprotection against seizure induced cell death.
Neuroscience188109-16(2011 Aug)
Holtman L,van Vliet EA,Baas F,Aronica E,Gorter JA

Complement inhibition accelerates regeneration in a model of peripheral nerve injury.
Molecular immunology47(2-3)302-9(2009 Dec)
Ramaglia V,Tannemaat MR,de Kok M,Wolterman R,Vigar MA,King RH,Morgan BP,Baas F

Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.
Molecular immunology46(5)803-11(2009 Feb)
Ruseva MM,Hughes TR,Donev RM,Sivasankar B,Pickering MC,Wu X,Harris CL,Morgan BP

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C6 cDNA ORF clone, Rattus norvegicus(Norway rat)

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Target ORF information:

Target ORF information:

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ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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Target ORF information:

ORF Insert Sequence:

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