Overview

About the MicroRNAs in cancer pathway

MicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or the inhibition of protein translation. Using high-throughput profiling, dysregulation of miRNAs has been widely observed in different stages of cancer.

The longest variant of each gene is displayed. Click the see gene variants link to see all gene variants.

297 geneClick for more »

Gene Symbol Full Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
APC adenomatous polyposis coli
RHOA ras homolog family member A
ATM ATM serine/threonine kinase
BAK1 BCL2-antagonist/killer 1
CCND1 cyclin D1
BCL2 B-cell CLL/lymphoma 2
BCL2L2 BCL2-like 2
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA1 breast cancer 1, early onset
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCND2 cyclin D2
CCNE1 cyclin E1
CCNG1 cyclin G1
CD44 CD44 molecule (Indian blood group)
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CREBBP CREB binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FGFR3 fibroblast growth factor receptor 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
GLS glutaminase
GRB2 growth factor receptor-bound protein 2
HDAC1 histone deacetylase 1
HMOX1 heme oxygenase 1
HNRNPK heterogeneous nuclear ribonucleoprotein K
HOXD10 homeobox D10
HRAS Harvey rat sarcoma viral oncogene homolog
TNC tenascin C
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IRS1 insulin receptor substrate 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KRAS Kirsten rat sarcoma viral oncogene homolog
STMN1 stathmin 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MMP9 matrix metallopeptidase 9
MMP16 matrix metallopeptidase 16 (membrane-inserted)
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLAU plasminogen activator, urokinase
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
MAPK1 mitogen-activated protein kinase 1
MAPK7 mitogen-activated protein kinase 7
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RDX radixin
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
FSCN1 fascin actin-bundling protein 1
SOS1 son of sevenless homolog 1 (Drosophila)

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