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Kremen2 cDNA ORF clone, Rattus norvegicus(Norway rat)

Summary

Gene Symbol Kremen2
Entrez Gene ID 287102
Full Name kringle containing transmembrane protein 2
General protein information
Preferred Names

kringle containing transmembrane protein 2

Names

kremen protein 2
Gene Type protein-coding
Organism Rattus norvegicus(Norway rat)
Genome

10

10q12

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001105767.1 NP_001099237.1 kremen protein 2 precursor
XM_017597062.1 XP_017452551.1 kremen protein 2 isoform X1
XM_017597061.1 XP_017452550.1 kremen protein 2 isoform X1
XM_008767550.2 XP_008765772.1 kremen protein 2 isoform X2
XM_008767551.2 XP_008765773.1 kremen protein 2 isoform X3

Pathways from BioSystems


Homologies


Mus musculus (house mouse) Kremen2 NP_082692.1
Homo sapiens (human) KREMEN2 NP_757384.1
Canis lupus familiaris (dog) KREMEN2 XP_005621717.1
Rattus norvegicus (Norway rat) Kremen2 NP_001099237.1

Gene Ontology


Bibliography

Related articles in PubMed

Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density.
Ellwanger K, Saito H, Cl?ment-Lacroix P, Maltry N, Niedermeyer J, Lee WK, Baron R, Rawadi G, Westphal H, Niehrs C
Molecular and cellular biology28(15)4875-82(2008 Aug)

Function and biological roles of the Dickkopf family of Wnt modulators.
Niehrs C
Oncogene25(57)7469-81(2006 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Kremen2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Kremen2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
ORa04286 NM_001105767.1
Latest version!		 Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
ORa04286 XM_017597061.1
Latest version!		 Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
ORa04286 XM_017597062.1
Latest version!		 Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
ORa32808 XM_008767550.2
Latest version!		 Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
ORa44562 XM_008767551.2
Latest version!		 Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X4, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID ORa04286
Clone ID Related Accession (Same CDS sequence) NM_001105767.1 , XM_017597062.1 , XM_017597061.1
Accession Version NM_001105767.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1407bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Rattus norvegicus(Norway rat)
Product kremen protein 2 precursor
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Oct 3, 2007 this sequence version replaced XM_001056095.1, XM_220206.4. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN01906350 [ECO:0000350] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGGTGA GGCTGATTTG CAAGCCCGAG TCTTCTCCAC CGTGATGGCC 
ATCTCTGTGC TGCTGCTGCT GCTGCTCCTG TCGCTACTGC GTTTGCTGCG TCGACGGAGC 
TGTCTGCTGG CTCCAGGAAA AGGGTCTCTG GCCATGGGAC CTTCCCGGGG CCCCGGGAGA 
AGCTGGGCTG TGTGGTACCG CCGGCCCCGA GGGGTGGCCC TGCCCTGTCC CCCAGGGGAC 
TCTCAGGCTG AGGGTCCTGC TGCGGGCTAC CGGCCCCTGA GTGCCTCCAG CCAGAGCTCC 
TTGCGCTCGC TCGTCTCTGC TCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001099237.1
CDS140..1546
Translation

Target ORF information:

RefSeq Version NM_001105767.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001105767.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGGTGA GGCTGATTTG CAAGCCCGAG TCTTCTCCAC CGTGATGGCC 
ATCTCTGTGC TGCTGCTGCT GCTGCTCCTG TCGCTACTGC GTTTGCTGCG TCGACGGAGC 
TGTCTGCTGG CTCCAGGAAA AGGGTCTCTG GCCATGGGAC CTTCCCGGGG CCCCGGGAGA 
AGCTGGGCTG TGTGGTACCG CCGGCCCCGA GGGGTGGCCC TGCCCTGTCC CCCAGGGGAC 
TCTCAGGCTG AGGGTCCTGC TGCGGGCTAC CGGCCCCTGA GTGCCTCCAG CCAGAGCTCC 
TTGCGCTCGC TCGTCTCTGC TCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa04286
Clone ID Related Accession (Same CDS sequence) NM_001105767.1 , XM_017597062.1 , XM_017597061.1
Accession Version XM_017597062.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1407bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product kremen protein 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGGTGA GGCTGATTTG CAAGCCCGAG TCTTCTCCAC CGTGATGGCC 
ATCTCTGTGC TGCTGCTGCT GCTGCTCCTG TCGCTACTGC GTTTGCTGCG TCGACGGAGC 
TGTCTGCTGG CTCCAGGAAA AGGGTCTCTG GCCATGGGAC CTTCCCGGGG CCCCGGGAGA 
AGCTGGGCTG TGTGGTACCG CCGGCCCCGA GGGGTGGCCC TGCCCTGTCC CCCAGGGGAC 
TCTCAGGCTG AGGGTCCTGC TGCGGGCTAC CGGCCCCTGA GTGCCTCCAG CCAGAGCTCC 
TTGCGCTCGC TCGTCTCTGC TCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017452551.1
CDS647..2053
Translation

Target ORF information:

RefSeq Version XM_017597062.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017597062.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGGTGA GGCTGATTTG CAAGCCCGAG TCTTCTCCAC CGTGATGGCC 
ATCTCTGTGC TGCTGCTGCT GCTGCTCCTG TCGCTACTGC GTTTGCTGCG TCGACGGAGC 
TGTCTGCTGG CTCCAGGAAA AGGGTCTCTG GCCATGGGAC CTTCCCGGGG CCCCGGGAGA 
AGCTGGGCTG TGTGGTACCG CCGGCCCCGA GGGGTGGCCC TGCCCTGTCC CCCAGGGGAC 
TCTCAGGCTG AGGGTCCTGC TGCGGGCTAC CGGCCCCTGA GTGCCTCCAG CCAGAGCTCC 
TTGCGCTCGC TCGTCTCTGC TCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa04286
Clone ID Related Accession (Same CDS sequence) NM_001105767.1 , XM_017597062.1 , XM_017597061.1
Accession Version XM_017597061.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1407bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product kremen protein 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGGTGA GGCTGATTTG CAAGCCCGAG TCTTCTCCAC CGTGATGGCC 
ATCTCTGTGC TGCTGCTGCT GCTGCTCCTG TCGCTACTGC GTTTGCTGCG TCGACGGAGC 
TGTCTGCTGG CTCCAGGAAA AGGGTCTCTG GCCATGGGAC CTTCCCGGGG CCCCGGGAGA 
AGCTGGGCTG TGTGGTACCG CCGGCCCCGA GGGGTGGCCC TGCCCTGTCC CCCAGGGGAC 
TCTCAGGCTG AGGGTCCTGC TGCGGGCTAC CGGCCCCTGA GTGCCTCCAG CCAGAGCTCC 
TTGCGCTCGC TCGTCTCTGC TCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_017452550.1
CDS850..2256
Translation

Target ORF information:

RefSeq Version XM_017597061.1
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017597061.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGGTGA GGCTGATTTG CAAGCCCGAG TCTTCTCCAC CGTGATGGCC 
ATCTCTGTGC TGCTGCTGCT GCTGCTCCTG TCGCTACTGC GTTTGCTGCG TCGACGGAGC 
TGTCTGCTGG CTCCAGGAAA AGGGTCTCTG GCCATGGGAC CTTCCCGGGG CCCCGGGAGA 
AGCTGGGCTG TGTGGTACCG CCGGCCCCGA GGGGTGGCCC TGCCCTGTCC CCCAGGGGAC 
TCTCAGGCTG AGGGTCCTGC TGCGGGCTAC CGGCCCCTGA GTGCCTCCAG CCAGAGCTCC 
TTGCGCTCGC TCGTCTCTGC TCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa32808
Clone ID Related Accession (Same CDS sequence) XM_008767550.2
Accession Version XM_008767550.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1389bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product kremen protein 2 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767550.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGCCCG AGTCTTCTCC ACCGTGATGG CCATCTCTGT GCTGCTGCTG 
CTGCTGCTCC TGTCGCTACT GCGTTTGCTG CGTCGACGGA GCTGTCTGCT GGCTCCAGGA 
AAAGGGTCTC TGGCCATGGG ACCTTCCCGG GGCCCCGGGA GAAGCTGGGC TGTGTGGTAC 
CGCCGGCCCC GAGGGGTGGC CCTGCCCTGT CCCCCAGGGG ACTCTCAGGC TGAGGGTCCT 
GCTGCGGGCT ACCGGCCCCT GAGTGCCTCC AGCCAGAGCT CCTTGCGCTC GCTCGTCTCT 
GCTCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008765772.1
CDS850..2238
Translation

Target ORF information:

RefSeq Version XM_008767550.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008767550.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGCCCG AGTCTTCTCC ACCGTGATGG CCATCTCTGT GCTGCTGCTG 
CTGCTGCTCC TGTCGCTACT GCGTTTGCTG CGTCGACGGA GCTGTCTGCT GGCTCCAGGA 
AAAGGGTCTC TGGCCATGGG ACCTTCCCGG GGCCCCGGGA GAAGCTGGGC TGTGTGGTAC 
CGCCGGCCCC GAGGGGTGGC CCTGCCCTGT CCCCCAGGGG ACTCTCAGGC TGAGGGTCCT 
GCTGCGGGCT ACCGGCCCCT GAGTGCCTCC AGCCAGAGCT CCTTGCGCTC GCTCGTCTCT 
GCTCTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID ORa44562
Clone ID Related Accession (Same CDS sequence) XM_008767551.2
Accession Version XM_008767551.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1203bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-07-25
Organism Rattus norvegicus(Norway rat)
Product kremen protein 2 isoform X3
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005109.4) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008767551.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGCCCG AGTCTTCTCC ACCGTGATGG CCATCTCTGT GCTGCTGCTG 
CTGCTGCTCC TGTCGCTACT GCGTTTGCTG CGTCGACGGT GCGGGCGCTG GGGCAGGGCC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_008765773.1
CDS850..2052
Translation

Target ORF information:

RefSeq Version XM_008767551.2
Organism Rattus norvegicus(Norway rat)
Definition Rattus norvegicus kringle containing transmembrane protein 2 (Kremen2), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_008767551.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
ATGGGGACAC CAGATCTGCA GGGCCTCCTC CTCCTCTTCC CGTTGCTGCT GCCGCCGCAC 
GGGGCCTCAG CAGGGAGCCT GCACAGTCCA GGCCTGTCCG AATGCTTCCA GGTGAACGGC 
GCTGACTACC GCGGCCACCA GAACTACACC GGCCCGCGCG GAGCTGGACG CCCTTGTCTT 
TTCTGGGACC AGACGCAGCA GCACAGCTAC AGCAGCGCCA GCGATCCCCA GGGCCGCTGG 
GGGCTGGGTG CGCACAACTT CTGTAGGAAC CCGGACGGCG ATGTGCAGCC CTGGTGCTAT 
GTGGCAGAGA CAGAAGAAGG CATCTACTGG CGCTACTGTG ATATCCCCAC GTGTCACATG 
CCTGGGTACC TGGGCTGCTT CGTAGACTCT GGGGCACCCC CTGCTCTCAG TGGTCCCAGT 
GGCACCTCCA CAAAGCTCAC AGTCCAGGTG TGCCTTCGAT TCTGCCGCAT GAAGGGCTAC 
CAGCTGGCTG GCGTGGAGGC TGGTTATGCC TGCTTCTGTG GCTCTGAAAG TGACCTGGCC 
CGGGGACGTC CAGCCCCTGC CACCGACTGT GACCAGATCT GTTTTGGCCA CCCAGGCCAA 
CTGTGTGGAG GTGATGGACG ACTGGGTATC TATGAAGTGT CTGTGGGTTC CTGCCAGGGA 
AACTGGACGG CTCCTCAGGG TGTCATCTAC TCCCCGGATT TTCCGGATGA GTATGGACCA 
GACCGGAACT GCAGCTGGGT ACTGGGCCAA CTGGGCGCTG TGCTAGAGCT CACCTTCCGC 
CTCTTCGAGT TGGCTGACTC TCGAGACCGG CTGGAGCTAC GCGACGCCTC ATCTGGCAAC 
CTGCTCCGTG CCTTCGACGG CGCCCATCCG CCGCCGCCCG GGCCGCTGCA CCTGCGCACT 
GCTGCACTGC TGCTCACCTT CCGCAGCGAC GCACGAGGCC ATGCTCAAGG CTTCGCGCTC 
ACCTACCGGG GGCTGCAGGA TACAGTGGAG GACAGAGCGT CTCCAGAGGA TTCAGCTGAG 
ACTCTCGCAG GGAACCCCGA TGGGGCTAAC GTGAGCTGCA GCCCCAAGCC TGGAGCGGCA 
CAGGCTTCCA TAGGTGCCCG AGTCTTCTCC ACCGTGATGG CCATCTCTGT GCTGCTGCTG 
CTGCTGCTCC TGTCGCTACT GCGTTTGCTG CGTCGACGGT GCGGGCGCTG GGGCAGGGCC 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density.
Molecular and cellular biology28(15)4875-82(2008 Aug)
Ellwanger K,Saito H,Cl?ment-Lacroix P,Maltry N,Niedermeyer J,Lee WK,Baron R,Rawadi G,Westphal H,Niehrs C


book

Function and biological roles of the Dickkopf family of Wnt modulators.
Oncogene25(57)7469-81(2006 Dec)
Niehrs C