| Gene Symbol | Pik3ap1 |
| Entrez Gene ID | 294048 |
| Full Name | phosphoinositide-3-kinase adaptor protein 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Rattus norvegicus(Norway rat) |
| Genome |
gRNAs
The following Pik3ap1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pik3ap1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ORa10921 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001106368.1 | |
| Accession Version | NM_001106368.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2373bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-09-30 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | phosphoinositide 3-kinase adapter protein 1 | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473986.1. On or before Oct 4, 2007 this sequence version replaced XM_001054196.1, XM_220008.4. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN01906355 [ECO:0000350] ##Evidence-Data-END## | |
1 | ATGGCAGCCT CAGGGTGGGG CTGGGGATGC GACATCCTCA TCTTCTACAG CCCAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001099838.1 |
| CDS | 87..2459 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001106368.1 |
1 | ATGGCAGCCT CAGGGTGGGG CTGGGGATGC GACATCCTCA TCTTCTACAG CCCAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa24086 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008760414.1 , XM_017589045.1 | |
| Accession Version | XM_008760414.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2439bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | phosphoinositide 3-kinase adapter protein 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCAGCCT CAGGGTGGGG CTGGGGATGC GACATCCTCA TCTTCTACAG CCCAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008758636.1 |
| CDS | 729..3167 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008760414.1 |
1 | ATGGCAGCCT CAGGGTGGGG CTGGGGATGC GACATCCTCA TCTTCTACAG CCCAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa24086 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008760414.1 , XM_017589045.1 | |
| Accession Version | XM_017589045.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2439bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | phosphoinositide 3-kinase adapter protein 1 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCAGCCT CAGGGTGGGG CTGGGGATGC GACATCCTCA TCTTCTACAG CCCAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_017444534.1 |
| CDS | 662..3100 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_017589045.1 |
1 | ATGGCAGCCT CAGGGTGGGG CTGGGGATGC GACATCCTCA TCTTCTACAG CCCAGATGCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ORa45183 | |
| Clone ID Related Accession (Same CDS sequence) | XM_008760416.2 | |
| Accession Version | XM_008760416.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2055bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2016-07-25 | |
| Organism | Rattus norvegicus(Norway rat) | |
| Product | phosphoinositide 3-kinase adapter protein 1 isoform X2 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_005100.4) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jul 26, 2016 this sequence version replaced XM_008760416.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Rattus norvegicus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCTGTTTC CCATCTCACA GGATGGTGGG GAGGATGACA CGGAGACGAA TTCTGGCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_008758638.1 |
| CDS | 1019..3073 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_008760416.2 |
1 | ATGCTGTTTC CCATCTCACA GGATGGTGGG GAGGATGACA CGGAGACGAA TTCTGGCTGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt. |
B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K. |
Identification of BCAP-(L) as a negative regulator of the TLR signaling-induced production of IL-6 and IL-10 in macrophages by tyrosine phosphoproteomics. |
Bioinformatics and cellular signaling. |
BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation. |
